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Volumn 70, Issue 3, 2012, Pages 471-475

A phase i trial of oral administration of panobinostat in combination with paclitaxel and carboplatin in patients with solid tumors

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; PACLITAXEL; PANOBINOSTAT; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

EID: 84866358085     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-012-1931-x     Document Type: Article
Times cited : (20)

References (9)
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  • 3
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    • Cytotoxicity mediated by histone deacetylase inhibitors in cancer cells: Mechanisms and potential clinical implications
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    • Schrump, D.S.1
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    • 67349228774 scopus 로고    scopus 로고
    • Development of the pan-DAC inhibitor panobinostat (LBH589): Successes and challenges
    • Atadja P (2009) Development of the pan-DAC inhibitor panobinostat (LBH589): successes and challenges. Cancer Lett 280(2): 233-241
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    • Atadja, P.1
  • 5
    • 77649171884 scopus 로고    scopus 로고
    • Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents
    • Tan J, Cang S, Ma Y, Petrillo RL, Liu D (2010) Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents. J Hematol Oncol 3:5
    • (2010) J Hematol Oncol , vol.3 , pp. 5
    • Tan, J.1    Cang, S.2    Ma, Y.3    Petrillo, R.L.4    Liu, D.5
  • 6
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    • Clinical studies of histone deacetylase inhibitors
    • Prince HM, Bishton MJ, Harrison SJ (2009) Clinical studies of histone deacetylase inhibitors. Clin Cancer Res 15:3958-3969
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    • Prince, H.M.1    Bishton, M.J.2    Harrison, S.J.3
  • 7
    • 84856038056 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor panobinostat demonstrates marked synergy with conventional chemotherapeutic agents in human ovarian cancer cell lines
    • Budman DR, Tai J, Calabro A, John V (2010) The histone deacetylase inhibitor panobinostat demonstrates marked synergy with conventional chemotherapeutic agents in human ovarian cancer cell lines. Invest New Drugs 29:1224-1229
    • (2010) Invest New Drugs , vol.29 , pp. 1224-1229
    • Budman, D.R.1    Tai, J.2    Calabro, A.3    John, V.4
  • 8
    • 79953725710 scopus 로고    scopus 로고
    • Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia
    • Bishton MJ, Harrison SJ, Martin BP et al (2011) Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia. Blood 117:3658-3668
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  • 9
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    • Clinically relevant QTc prolongation is not associated with current dose schedules of LBH589 (panobinostat)
    • Zhang L, Lebwohl D, Masson E et al (2008) Clinically relevant QTc prolongation is not associated with current dose schedules of LBH589 (panobinostat). J Clin Oncol 28:332-334
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    • Zhang, L.1    Lebwohl, D.2    Masson, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.