-
1
-
-
77956632843
-
Moving from prognostic to predictive factors in chronic lymphocytic leukaemia (CLL)
-
Zenz T., et al. Moving from prognostic to predictive factors in chronic lymphocytic leukaemia (CLL). Best Pract. Res. Clin. Haematol. 2010, 23(1):71-84.
-
(2010)
Best Pract. Res. Clin. Haematol.
, vol.23
, Issue.1
, pp. 71-84
-
-
Zenz, T.1
-
2
-
-
84891001835
-
Diffuse large B-cell lymphoma-treatment approaches in the molecular era
-
Roschewski M., Staudt L.M., Wilson W.H. Diffuse large B-cell lymphoma-treatment approaches in the molecular era. Nat Rev Clin Oncol 2014, 11(1):12-23.
-
(2014)
Nat Rev Clin Oncol
, vol.11
, Issue.1
, pp. 12-23
-
-
Roschewski, M.1
Staudt, L.M.2
Wilson, W.H.3
-
3
-
-
84874102335
-
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
-
Landau D.A., et al. Evolution and impact of subclonal mutations in chronic lymphocytic leukemia. Cell 2013, 152(4):714-726.
-
(2013)
Cell
, vol.152
, Issue.4
, pp. 714-726
-
-
Landau, D.A.1
-
4
-
-
84872856782
-
Genetic heterogeneity of diffuse large B-cell lymphoma
-
Zhang J., et al. Genetic heterogeneity of diffuse large B-cell lymphoma. Proc. Natl. Acad. Sci. U. S. A. 2013, 110(4):1398-1403.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, Issue.4
, pp. 1398-1403
-
-
Zhang, J.1
-
5
-
-
84907200622
-
Entering the era of targeted therapy for chronic lymphocytic leukemia: impact on the practicing clinician
-
Byrd J.C., et al. Entering the era of targeted therapy for chronic lymphocytic leukemia: impact on the practicing clinician. J. Clin. Oncol. 2014, 32(27):3039-3047.
-
(2014)
J. Clin. Oncol.
, vol.32
, Issue.27
, pp. 3039-3047
-
-
Byrd, J.C.1
-
6
-
-
84926137490
-
Life after ibrutinib? A new unmet need in CLL
-
Pinilla-Ibarz J., Chavez J.C. Life after ibrutinib? A new unmet need in CLL. Blood 2015, 125(13):2013-2014.
-
(2015)
Blood
, vol.125
, Issue.13
, pp. 2013-2014
-
-
Pinilla-Ibarz, J.1
Chavez, J.C.2
-
7
-
-
84941343751
-
Secondary mutations as mediators of resistance to targeted therapy in leukemia
-
Daver N., et al. Secondary mutations as mediators of resistance to targeted therapy in leukemia. Blood 2015, 125(21):3236-3245.
-
(2015)
Blood
, vol.125
, Issue.21
, pp. 3236-3245
-
-
Daver, N.1
-
8
-
-
84925611946
-
Microenvironmental regulation of therapeutic response in cancer
-
Klemm F., Joyce J.A. Microenvironmental regulation of therapeutic response in cancer. Trends Cell Biol. 2015, 25(4):198-213.
-
(2015)
Trends Cell Biol.
, vol.25
, Issue.4
, pp. 198-213
-
-
Klemm, F.1
Joyce, J.A.2
-
9
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144(5):646-674.
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
10
-
-
84928062583
-
Immune checkpoint blockade: a common denominator approach to cancer therapy
-
Topalian S.L., Drake C.G., Pardoll D.M. Immune checkpoint blockade: a common denominator approach to cancer therapy. Cancer Cell 2015, 27(4):450-461.
-
(2015)
Cancer Cell
, vol.27
, Issue.4
, pp. 450-461
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
11
-
-
84880507665
-
Mutational heterogeneity in cancer and the search for new cancer-associated genes
-
Lawrence M.S., et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature 2013, 499(7457):214-218.
-
(2013)
Nature
, vol.499
, Issue.7457
, pp. 214-218
-
-
Lawrence, M.S.1
-
12
-
-
84928770388
-
Neoantigens in cancer immunotherapy
-
Schumacher T.N., Schreiber R.D. Neoantigens in cancer immunotherapy. Science 2015, 348(6230):69-74.
-
(2015)
Science
, vol.348
, Issue.6230
, pp. 69-74
-
-
Schumacher, T.N.1
Schreiber, R.D.2
-
13
-
-
79953151458
-
Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion
-
Schreiber R.D., Old L.J., Smyth M.J. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 2011, 331(6024):1565-1570.
-
(2011)
Science
, vol.331
, Issue.6024
, pp. 1565-1570
-
-
Schreiber, R.D.1
Old, L.J.2
Smyth, M.J.3
-
14
-
-
0029924107
-
Human tumor antigens recognized by T lymphocytes
-
Boon T., van der Bruggen P. Human tumor antigens recognized by T lymphocytes. J Exp Med 1996, 183(3):725-729.
-
(1996)
J Exp Med
, vol.183
, Issue.3
, pp. 725-729
-
-
Boon, T.1
van der Bruggen, P.2
-
15
-
-
35548936833
-
Models, mechanisms and clinical evidence for cancer dormancy
-
Aguirre-Ghiso J.A. Models, mechanisms and clinical evidence for cancer dormancy. Nat. Rev. Cancer 2007, 7(11):834-846.
-
(2007)
Nat. Rev. Cancer
, vol.7
, Issue.11
, pp. 834-846
-
-
Aguirre-Ghiso, J.A.1
-
16
-
-
84875463042
-
Molecular mechanisms of T cell co-stimulation and co-inhibition
-
Chen L., Flies D.B. Molecular mechanisms of T cell co-stimulation and co-inhibition. Nat. Rev. Immunol. 2013, 13(4):227-242.
-
(2013)
Nat. Rev. Immunol.
, vol.13
, Issue.4
, pp. 227-242
-
-
Chen, L.1
Flies, D.B.2
-
17
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian S.L., et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 2012, 366(26):2443-2454.
-
(2012)
N. Engl. J. Med.
, vol.366
, Issue.26
, pp. 2443-2454
-
-
Topalian, S.L.1
-
18
-
-
0027087331
-
Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy
-
Schwartz R.H. Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell 1992, 71(7):1065-1068.
-
(1992)
Cell
, vol.71
, Issue.7
, pp. 1065-1068
-
-
Schwartz, R.H.1
-
19
-
-
65349119978
-
CD28 and CTLA-4 coreceptor expression and signal transduction
-
Rudd C.E., Taylor A., Schneider H. CD28 and CTLA-4 coreceptor expression and signal transduction. Immunol. Rev. 2009, 229(1):12-26.
-
(2009)
Immunol. Rev.
, vol.229
, Issue.1
, pp. 12-26
-
-
Rudd, C.E.1
Taylor, A.2
Schneider, H.3
-
20
-
-
84880305809
-
Immune checkpoint blockade immunotherapy to activate anti-tumour T-cell immunity
-
Ramsay A.G. Immune checkpoint blockade immunotherapy to activate anti-tumour T-cell immunity. Br. J. Haematol. 2013, 162(3):313-325.
-
(2013)
Br. J. Haematol.
, vol.162
, Issue.3
, pp. 313-325
-
-
Ramsay, A.G.1
-
21
-
-
79955529454
-
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4
-
Qureshi O.S., et al. Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. Science 2011, 332(6029):600-603.
-
(2011)
Science
, vol.332
, Issue.6029
, pp. 600-603
-
-
Qureshi, O.S.1
-
22
-
-
68149155982
-
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies
-
Peggs K.S., et al. Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies. J Exp Med 2009, 206(8):1717-1725.
-
(2009)
J Exp Med
, vol.206
, Issue.8
, pp. 1717-1725
-
-
Peggs, K.S.1
-
23
-
-
0031678645
-
Secondary but not primary T cell responses are enhanced in CTLA-4-deficient CD8+ T cells
-
Chambers C.A., et al. Secondary but not primary T cell responses are enhanced in CTLA-4-deficient CD8+ T cells. Eur. J. Immunol. 1998, 28(10):3137-3143.
-
(1998)
Eur. J. Immunol.
, vol.28
, Issue.10
, pp. 3137-3143
-
-
Chambers, C.A.1
-
24
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi F.S., et al. Improved survival with ipilimumab in patients with metastatic melanoma. N. Engl. J. Med. 2010, 363(8):711-723.
-
(2010)
N. Engl. J. Med.
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
-
25
-
-
27144559654
-
Increased expression of CD152 (CTLA-4) by normal T lymphocytes in untreated patients with B-cell chronic lymphocytic leukemia
-
Motta M., et al. Increased expression of CD152 (CTLA-4) by normal T lymphocytes in untreated patients with B-cell chronic lymphocytic leukemia. Leukemia 2005, 19(10):1788-1793.
-
(2005)
Leukemia
, vol.19
, Issue.10
, pp. 1788-1793
-
-
Motta, M.1
-
26
-
-
70350244852
-
Phase I study of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with relapsed and refractory B-cell non-Hodgkin lymphoma
-
Ansell S.M., et al. Phase I study of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with relapsed and refractory B-cell non-Hodgkin lymphoma. Clin. Cancer Res. 2009, 15(20):6446-6453.
-
(2009)
Clin. Cancer Res.
, vol.15
, Issue.20
, pp. 6446-6453
-
-
Ansell, S.M.1
-
27
-
-
84864324543
-
Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2
-
Yokosuka T., et al. Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2. J Exp Med 2012, 209(6):1201-1217.
-
(2012)
J Exp Med
, vol.209
, Issue.6
, pp. 1201-1217
-
-
Yokosuka, T.1
-
28
-
-
42649125225
-
PD-1 and its ligands in tolerance and immunity
-
Keir M.E., et al. PD-1 and its ligands in tolerance and immunity. Annu. Rev. Immunol. 2008, 26:677-704.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
-
29
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
Barber D.L., et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 2006, 439(7077):682-687.
-
(2006)
Nature
, vol.439
, Issue.7077
, pp. 682-687
-
-
Barber, D.L.1
-
30
-
-
73949088551
-
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
-
Francisco L.M., et al. PD-L1 regulates the development, maintenance, and function of induced regulatory T cells. J Exp Med 2009, 206(13):3015-3029.
-
(2009)
J Exp Med
, vol.206
, Issue.13
, pp. 3015-3029
-
-
Francisco, L.M.1
-
31
-
-
61349139964
-
Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells
-
Liu Y., et al. Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells. Cancer Immunol. Immunother. 2009, 58(5):687-697.
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, Issue.5
, pp. 687-697
-
-
Liu, Y.1
-
32
-
-
55249113863
-
B7-H1 on myeloid-derived suppressor cells in immune suppression by a mouse model of ovarian cancer
-
Liu Y., et al. B7-H1 on myeloid-derived suppressor cells in immune suppression by a mouse model of ovarian cancer. Clin. Immunol. 2008, 129(3):471-481.
-
(2008)
Clin. Immunol.
, vol.129
, Issue.3
, pp. 471-481
-
-
Liu, Y.1
-
33
-
-
34447646310
-
Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses
-
Butte M.J., et al. Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity 2007, 27(1):111-122.
-
(2007)
Immunity
, vol.27
, Issue.1
, pp. 111-122
-
-
Butte, M.J.1
-
34
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer J.R., et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N. Engl. J. Med. 2012, 366(26):2455-2465.
-
(2012)
N. Engl. J. Med.
, vol.366
, Issue.26
, pp. 2455-2465
-
-
Brahmer, J.R.1
-
35
-
-
84925221855
-
PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma
-
Ansell S.M., et al. PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma. N. Engl. J. Med. 2015, 372(4):311-319.
-
(2015)
N. Engl. J. Med.
, vol.372
, Issue.4
, pp. 311-319
-
-
Ansell, S.M.1
-
36
-
-
49649114804
-
Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
-
Berger R., et al. Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin. Cancer Res. 2008, 14(10):3044-3051.
-
(2008)
Clin. Cancer Res.
, vol.14
, Issue.10
, pp. 3044-3051
-
-
Berger, R.1
-
37
-
-
84930960194
-
Immune checkpoint blockade in hematologic malignancies
-
Armand P. Immune checkpoint blockade in hematologic malignancies. Blood 2015.
-
(2015)
Blood
-
-
Armand, P.1
-
38
-
-
84890096527
-
Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: results of an international phase II trial
-
Armand P., et al. Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: results of an international phase II trial. J. Clin. Oncol. 2013, 31(33):4199-4206.
-
(2013)
J. Clin. Oncol.
, vol.31
, Issue.33
, pp. 4199-4206
-
-
Armand, P.1
-
39
-
-
0034667624
-
Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1
-
Burger J.A., et al. Blood-derived nurse-like cells protect chronic lymphocytic leukemia B cells from spontaneous apoptosis through stromal cell-derived factor-1. Blood 2000, 96(8):2655-2663.
-
(2000)
Blood
, vol.96
, Issue.8
, pp. 2655-2663
-
-
Burger, J.A.1
-
40
-
-
0030048565
-
Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro
-
Panayiotidis P., et al. Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro. Br. J. Haematol. 1996, 92(1):97-103.
-
(1996)
Br. J. Haematol.
, vol.92
, Issue.1
, pp. 97-103
-
-
Panayiotidis, P.1
-
41
-
-
0032055818
-
Chronic lymphocytic leukemic B cells but not normal B cells are rescued from apoptosis by contact with normal bone marrow stromal cells
-
Lagneaux L., et al. Chronic lymphocytic leukemic B cells but not normal B cells are rescued from apoptosis by contact with normal bone marrow stromal cells. Blood 1998, 91(7):2387-2396.
-
(1998)
Blood
, vol.91
, Issue.7
, pp. 2387-2396
-
-
Lagneaux, L.1
-
42
-
-
84892868891
-
The microenvironment in chronic lymphocytic leukemia (CLL) and other B cell malignancies: insight into disease biology and new targeted therapies
-
Burger J.A., Gribben J.G. The microenvironment in chronic lymphocytic leukemia (CLL) and other B cell malignancies: insight into disease biology and new targeted therapies. Semin. Cancer Biol. 2014, 24:71-81.
-
(2014)
Semin. Cancer Biol.
, vol.24
, pp. 71-81
-
-
Burger, J.A.1
Gribben, J.G.2
-
43
-
-
84930976043
-
The classical Hodgkin lymphoma tumor microenvironment: macrophages and gene expression-based modeling
-
Scott D.W., Steidl C. The classical Hodgkin lymphoma tumor microenvironment: macrophages and gene expression-based modeling. Hematol. Am. Sociol. Hematol. Educ. Prog. 2014, 2014(1):144-150.
-
(2014)
Hematol. Am. Sociol. Hematol. Educ. Prog.
, vol.2014
, Issue.1
, pp. 144-150
-
-
Scott, D.W.1
Steidl, C.2
-
44
-
-
0028335475
-
Proliferation centres in B-cell malignant lymphoma, lymphocytic (B-CLL): an immunophenotypic study
-
Schmid C., Isaacson P.G. Proliferation centres in B-cell malignant lymphoma, lymphocytic (B-CLL): an immunophenotypic study. Histopathology 1994, 24(5):445-451.
-
(1994)
Histopathology
, vol.24
, Issue.5
, pp. 445-451
-
-
Schmid, C.1
Isaacson, P.G.2
-
45
-
-
23044514711
-
Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha
-
Nishio M., et al. Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha. Blood 2005, 106(3):1012-1020.
-
(2005)
Blood
, vol.106
, Issue.3
, pp. 1012-1020
-
-
Nishio, M.1
-
46
-
-
17044406054
-
CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival
-
Deaglio S., et al. CD38 and CD100 lead a network of surface receptors relaying positive signals for B-CLL growth and survival. Blood 2005, 105(8):3042-3050.
-
(2005)
Blood
, vol.105
, Issue.8
, pp. 3042-3050
-
-
Deaglio, S.1
-
47
-
-
77953517375
-
Monocytes/macrophages but not T lymphocytes are the major targets of the CCL3/CCL4 chemokines produced by CD38(+)CD49d(+) chronic lymphocytic leukaemia cells
-
Zucchetto A., et al. Monocytes/macrophages but not T lymphocytes are the major targets of the CCL3/CCL4 chemokines produced by CD38(+)CD49d(+) chronic lymphocytic leukaemia cells. Br. J. Haematol. 2010, 150(1):111-113.
-
(2010)
Br. J. Haematol.
, vol.150
, Issue.1
, pp. 111-113
-
-
Zucchetto, A.1
-
48
-
-
64049093376
-
High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation
-
Burger J.A., et al. High-level expression of the T-cell chemokines CCL3 and CCL4 by chronic lymphocytic leukemia B cells in nurselike cell cocultures and after BCR stimulation. Blood 2009, 113(13):3050-3058.
-
(2009)
Blood
, vol.113
, Issue.13
, pp. 3050-3058
-
-
Burger, J.A.1
-
49
-
-
84964310837
-
Tumor-associated macrophages in diffuse large B-cell lymphoma
-
Kridel R., Steidl C., Gascoyne R.D. Tumor-associated macrophages in diffuse large B-cell lymphoma. Haematologica 2015, 100(2):143-145.
-
(2015)
Haematologica
, vol.100
, Issue.2
, pp. 143-145
-
-
Kridel, R.1
Steidl, C.2
Gascoyne, R.D.3
-
50
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
Qian B.Z., Pollard J.W. Macrophage diversity enhances tumor progression and metastasis. Cell 2010, 141(1):39-51.
-
(2010)
Cell
, vol.141
, Issue.1
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
51
-
-
84856515333
-
Expansion of a CD8(+)PD-1(+) replicative senescence phenotype in early stage CLL patients is associated with inverted CD4:CD8 ratios and disease progression
-
Nunes C., et al. Expansion of a CD8(+)PD-1(+) replicative senescence phenotype in early stage CLL patients is associated with inverted CD4:CD8 ratios and disease progression. Clin. Cancer Res. 2012, 18(3):678-687.
-
(2012)
Clin. Cancer Res.
, vol.18
, Issue.3
, pp. 678-687
-
-
Nunes, C.1
-
52
-
-
46749145421
-
CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment
-
Patten P.E., et al. CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment. Blood 2008, 111(10):5173-5181.
-
(2008)
Blood
, vol.111
, Issue.10
, pp. 5173-5181
-
-
Patten, P.E.1
-
53
-
-
0036099832
-
Chronic lymphocytic leukemia B cells are endowed with the capacity to attract CD4+, CD40L+ T cells by producing CCL22
-
Ghia P., et al. Chronic lymphocytic leukemia B cells are endowed with the capacity to attract CD4+, CD40L+ T cells by producing CCL22. Eur. J. Immunol. 2002, 32(5):1403-1413.
-
(2002)
Eur. J. Immunol.
, vol.32
, Issue.5
, pp. 1403-1413
-
-
Ghia, P.1
-
54
-
-
84891724073
-
IL-21 and CD40L signals from autologous T cells can induce antigen-independent proliferation of CLL cells
-
Pascutti M.F., et al. IL-21 and CD40L signals from autologous T cells can induce antigen-independent proliferation of CLL cells. Blood 2013, 122(17):3010-3019.
-
(2013)
Blood
, vol.122
, Issue.17
, pp. 3010-3019
-
-
Pascutti, M.F.1
-
55
-
-
84865165316
-
Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer
-
Ramsay A.G., et al. Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer. Blood 2012, 120(7):1412-1421.
-
(2012)
Blood
, vol.120
, Issue.7
, pp. 1412-1421
-
-
Ramsay, A.G.1
-
56
-
-
84876478036
-
T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production
-
Riches J.C., et al. T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production. Blood 2013, 121(9):1612-1621.
-
(2013)
Blood
, vol.121
, Issue.9
, pp. 1612-1621
-
-
Riches, J.C.1
-
57
-
-
0035253726
-
Cd4+ T-cell immune response to large B-cell non-Hodgkin's lymphoma predicts patient outcome
-
Ansell S.M., et al. Cd4+ T-cell immune response to large B-cell non-Hodgkin's lymphoma predicts patient outcome. J. Clin. Oncol. 2001, 19(3):720-726.
-
(2001)
J. Clin. Oncol.
, vol.19
, Issue.3
, pp. 720-726
-
-
Ansell, S.M.1
-
58
-
-
84875599182
-
CD4(+) tumor infiltrating lymphocytes are prognostic and independent of R-IPI in patients with DLBCL receiving R-CHOP chemo-immunotherapy
-
Keane C., et al. CD4(+) tumor infiltrating lymphocytes are prognostic and independent of R-IPI in patients with DLBCL receiving R-CHOP chemo-immunotherapy. Am. J. Hematol. 2013, 88(4):273-276.
-
(2013)
Am. J. Hematol.
, vol.88
, Issue.4
, pp. 273-276
-
-
Keane, C.1
-
59
-
-
77956324601
-
CD40 is a potential marker of favorable prognosis in patients with diffuse large B-cell lymphoma treated with immunochemotherapy
-
Rydstrom K., et al. CD40 is a potential marker of favorable prognosis in patients with diffuse large B-cell lymphoma treated with immunochemotherapy. Leuk. Lymphoma 2010, 51(9):1643-1648.
-
(2010)
Leuk. Lymphoma
, vol.51
, Issue.9
, pp. 1643-1648
-
-
Rydstrom, K.1
-
60
-
-
36749013021
-
Distribution patterns of dendritic cells and T cells in diffuse large B-cell lymphomas correlate with prognoses
-
Chang K.C., et al. Distribution patterns of dendritic cells and T cells in diffuse large B-cell lymphomas correlate with prognoses. Clin. Cancer Res. 2007, 13(22 Pt 1):6666-6672.
-
(2007)
Clin. Cancer Res.
, vol.13
, Issue.22
, pp. 6666-6672
-
-
Chang, K.C.1
-
61
-
-
20144382754
-
Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response
-
Monti S., et al. Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response. Blood 2005, 105(5):1851-1861.
-
(2005)
Blood
, vol.105
, Issue.5
, pp. 1851-1861
-
-
Monti, S.1
-
62
-
-
84880747672
-
Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance
-
Zitvogel L., et al. Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance. Immunity 2013, 39(1):74-88.
-
(2013)
Immunity
, vol.39
, Issue.1
, pp. 74-88
-
-
Zitvogel, L.1
-
63
-
-
84924661679
-
Revisiting the immune microenvironment of diffuse large B-cell lymphoma using a tissue microarray and immunohistochemistry: robust semi-automated analysis reveals CD3 and FoxP3 as potential predictors of response to R-CHOP
-
Coutinho R., et al. Revisiting the immune microenvironment of diffuse large B-cell lymphoma using a tissue microarray and immunohistochemistry: robust semi-automated analysis reveals CD3 and FoxP3 as potential predictors of response to R-CHOP. Haematologica 2015, 100(3):363-369.
-
(2015)
Haematologica
, vol.100
, Issue.3
, pp. 363-369
-
-
Coutinho, R.1
-
64
-
-
70249085585
-
Stromal cell contributions to the homeostasis and functionality of the immune system
-
Mueller S.N., Germain R.N. Stromal cell contributions to the homeostasis and functionality of the immune system. Nat. Rev. Immunol. 2009, 9(9):618-629.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, Issue.9
, pp. 618-629
-
-
Mueller, S.N.1
Germain, R.N.2
-
65
-
-
33750301858
-
Magnitude of stromal hemangiogenesis correlates with histologic subtype of non-Hodgkin's lymphoma
-
Ruan J., et al. Magnitude of stromal hemangiogenesis correlates with histologic subtype of non-Hodgkin's lymphoma. Clin. Cancer Res. 2006, 12(19):5622-5631.
-
(2006)
Clin. Cancer Res.
, vol.12
, Issue.19
, pp. 5622-5631
-
-
Ruan, J.1
-
66
-
-
73349126115
-
Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance
-
Kurtova A.V., et al. Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance. Blood 2009, 114(20):4441-4450.
-
(2009)
Blood
, vol.114
, Issue.20
, pp. 4441-4450
-
-
Kurtova, A.V.1
-
67
-
-
84872387409
-
Protein kinase c-beta-dependent activation of NF-kappaB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo
-
Lutzny G., et al. Protein kinase c-beta-dependent activation of NF-kappaB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo. Cancer Cell 2013, 23(1):77-92.
-
(2013)
Cancer Cell
, vol.23
, Issue.1
, pp. 77-92
-
-
Lutzny, G.1
-
68
-
-
77950352713
-
Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression
-
Ghosh A.K., et al. Circulating microvesicles in B-cell chronic lymphocytic leukemia can stimulate marrow stromal cells: implications for disease progression. Blood 2010, 115(9):1755-1764.
-
(2010)
Blood
, vol.115
, Issue.9
, pp. 1755-1764
-
-
Ghosh, A.K.1
-
69
-
-
77958178317
-
Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch
-
Ding W., et al. Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch. Blood 2010, 116(16):2984-2993.
-
(2010)
Blood
, vol.116
, Issue.16
, pp. 2984-2993
-
-
Ding, W.1
-
70
-
-
70350459031
-
Bi-directional activation between mesenchymal stem cells and CLL B-cells: implication for CLL disease progression
-
Ding W., et al. Bi-directional activation between mesenchymal stem cells and CLL B-cells: implication for CLL disease progression. Br. J. Haematol. 2009, 147(4):471-483.
-
(2009)
Br. J. Haematol.
, vol.147
, Issue.4
, pp. 471-483
-
-
Ding, W.1
-
71
-
-
79960735663
-
Bone marrow stromal cell-derived vascular endothelial growth factor (VEGF) rather than chronic lymphocytic leukemia (CLL) cell-derived VEGF is essential for the apoptotic resistance of cultured CLL cells
-
Gehrke I., et al. Bone marrow stromal cell-derived vascular endothelial growth factor (VEGF) rather than chronic lymphocytic leukemia (CLL) cell-derived VEGF is essential for the apoptotic resistance of cultured CLL cells. Mol. Med. 2011, 17(7-8):619-627.
-
(2011)
Mol. Med.
, vol.17
, Issue.7-8
, pp. 619-627
-
-
Gehrke, I.1
-
72
-
-
84942457204
-
Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts
-
Paggetti J., et al. Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts. Blood 2015.
-
(2015)
Blood
-
-
Paggetti, J.1
-
73
-
-
57149089307
-
Stromal gene signatures in large-B-cell lymphomas
-
Lenz G., et al. Stromal gene signatures in large-B-cell lymphomas. N. Engl. J. Med. 2008, 359(22):2313-2323.
-
(2008)
N. Engl. J. Med.
, vol.359
, Issue.22
, pp. 2313-2323
-
-
Lenz, G.1
-
74
-
-
84860309799
-
Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis: a study of the Osaka lymphoma study group
-
Wada N., et al. Diffuse large B cell lymphoma with an interfollicular pattern of proliferation shows a favourable prognosis: a study of the Osaka lymphoma study group. Histopathology 2012, 60(6):924-932.
-
(2012)
Histopathology
, vol.60
, Issue.6
, pp. 924-932
-
-
Wada, N.1
-
75
-
-
84909980026
-
Microvascular density, CD68 and tryptase expression in human diffuse large B-cell lymphoma
-
Marinaccio C., et al. Microvascular density, CD68 and tryptase expression in human diffuse large B-cell lymphoma. Leuk. Res. 2014, 38(11):1374-1377.
-
(2014)
Leuk. Res.
, vol.38
, Issue.11
, pp. 1374-1377
-
-
Marinaccio, C.1
-
76
-
-
80955133848
-
Cross-talk between chronic lymphocytic leukemia cells and bone marrow endothelial cells: role of signal transducer and activator of transcription 3
-
Badoux X., et al. Cross-talk between chronic lymphocytic leukemia cells and bone marrow endothelial cells: role of signal transducer and activator of transcription 3. Hum. Pathol. 2011, 42(12):1989-2000.
-
(2011)
Hum. Pathol.
, vol.42
, Issue.12
, pp. 1989-2000
-
-
Badoux, X.1
-
77
-
-
0037154156
-
Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization
-
Suzuma K., et al. Characterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization. Proc. Natl. Acad. Sci. U. S. A. 2002, 99(2):721-726.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, Issue.2
, pp. 721-726
-
-
Suzuma, K.1
-
78
-
-
84862627044
-
Stromal endothelial cells establish a bidirectional crosstalk with chronic lymphocytic leukemia cells through the TNF-related factors BAFF, APRIL, and CD40L
-
Cols M., et al. Stromal endothelial cells establish a bidirectional crosstalk with chronic lymphocytic leukemia cells through the TNF-related factors BAFF, APRIL, and CD40L. J. Immunol. 2012, 188(12):6071-6083.
-
(2012)
J. Immunol.
, vol.188
, Issue.12
, pp. 6071-6083
-
-
Cols, M.1
-
79
-
-
84862121791
-
Physical contact with endothelial cells through beta1- and beta2-integrins rescues chronic lymphocytic leukemia cells from spontaneous and drug-induced apoptosis and induces a peculiar gene expression profile in leukemic cells
-
Maffei R., et al. Physical contact with endothelial cells through beta1- and beta2-integrins rescues chronic lymphocytic leukemia cells from spontaneous and drug-induced apoptosis and induces a peculiar gene expression profile in leukemic cells. Haematologica 2012, 97(6):952-960.
-
(2012)
Haematologica
, vol.97
, Issue.6
, pp. 952-960
-
-
Maffei, R.1
-
80
-
-
77949524521
-
Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion
-
Huang X., et al. Lymphoma endothelium preferentially expresses Tim-3 and facilitates the progression of lymphoma by mediating immune evasion. J Exp Med 2010, 207(3):505-520.
-
(2010)
J Exp Med
, vol.207
, Issue.3
, pp. 505-520
-
-
Huang, X.1
-
81
-
-
0036720390
-
Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1
-
Pedersen I.M., et al. Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1. Blood 2002, 100(5):1795-1801.
-
(2002)
Blood
, vol.100
, Issue.5
, pp. 1795-1801
-
-
Pedersen, I.M.1
-
82
-
-
84915745531
-
Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B-cell activation and proliferation
-
Heinig K., et al. Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B-cell activation and proliferation. Cancer Discov 2014, 4(12):1448-1465.
-
(2014)
Cancer Discov
, vol.4
, Issue.12
, pp. 1448-1465
-
-
Heinig, K.1
-
84
-
-
0037080021
-
Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism
-
Mazzoni A., et al. Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism. J. Immunol. 2002, 168(2):689-695.
-
(2002)
J. Immunol.
, vol.168
, Issue.2
, pp. 689-695
-
-
Mazzoni, A.1
-
85
-
-
0035339932
-
Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells
-
Gabrilovich D.I., et al. Mechanism of immune dysfunction in cancer mediated by immature Gr-1+ myeloid cells. J. Immunol. 2001, 166(9):5398-5406.
-
(2001)
J. Immunol.
, vol.166
, Issue.9
, pp. 5398-5406
-
-
Gabrilovich, D.I.1
-
86
-
-
11844277698
-
Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease
-
Sinha P., Clements V.K., Ostrand-Rosenberg S. Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease. J. Immunol. 2005, 174(2):636-645.
-
(2005)
J. Immunol.
, vol.174
, Issue.2
, pp. 636-645
-
-
Sinha, P.1
Clements, V.K.2
Ostrand-Rosenberg, S.3
-
87
-
-
34248342290
-
Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host
-
Liu C., et al. Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host. Blood 2007, 109(10):4336-4342.
-
(2007)
Blood
, vol.109
, Issue.10
, pp. 4336-4342
-
-
Liu, C.1
-
88
-
-
84905112825
-
CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs
-
Jitschin R., et al. CLL-cells induce IDOhi CD14+HLA-DRlo myeloid-derived suppressor cells that inhibit T-cell responses and promote TRegs. Blood 2014, 124(5):750-760.
-
(2014)
Blood
, vol.124
, Issue.5
, pp. 750-760
-
-
Jitschin, R.1
-
89
-
-
78751689059
-
Immunosuppressive CD14+HLA-DR(low)/- monocytes in B-cell non-Hodgkin lymphoma
-
Lin Y., et al. Immunosuppressive CD14+HLA-DR(low)/- monocytes in B-cell non-Hodgkin lymphoma. Blood 2011, 117(3):872-881.
-
(2011)
Blood
, vol.117
, Issue.3
, pp. 872-881
-
-
Lin, Y.1
-
90
-
-
33750535641
-
Attenuation of CD8(+) T-cell function by CD4(+)CD25(+) regulatory T cells in B-cell non-Hodgkin's lymphoma
-
Yang Z.Z., et al. Attenuation of CD8(+) T-cell function by CD4(+)CD25(+) regulatory T cells in B-cell non-Hodgkin's lymphoma. Cancer Res. 2006, 66(20):10145-10152.
-
(2006)
Cancer Res.
, vol.66
, Issue.20
, pp. 10145-10152
-
-
Yang, Z.Z.1
-
91
-
-
58549108182
-
Disruption of T cell suppression in chronic lymphocytic leukemia by CD200 blockade
-
Pallasch C.P., et al. Disruption of T cell suppression in chronic lymphocytic leukemia by CD200 blockade. Leuk. Res. 2009, 33(3):460-464.
-
(2009)
Leuk. Res.
, vol.33
, Issue.3
, pp. 460-464
-
-
Pallasch, C.P.1
-
92
-
-
24744432528
-
Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine
-
Beyer M., et al. Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine. Blood 2005, 106(6):2018-2025.
-
(2005)
Blood
, vol.106
, Issue.6
, pp. 2018-2025
-
-
Beyer, M.1
-
93
-
-
0021336528
-
Impaired natural killer activity in patients with chronic lymphocytic leukemia is associated with a deficiency of azurophilic cytoplasmic granules in putative NK cells
-
Kay N.E., Zarling J.M. Impaired natural killer activity in patients with chronic lymphocytic leukemia is associated with a deficiency of azurophilic cytoplasmic granules in putative NK cells. Blood 1984, 63(2):305-309.
-
(1984)
Blood
, vol.63
, Issue.2
, pp. 305-309
-
-
Kay, N.E.1
Zarling, J.M.2
-
94
-
-
0024505340
-
Malignant chronic lymphocytic leukemia B cells elaborate soluble factors that down-regulate T cell and NK function
-
Burton J.D., Weitz C.H., Kay N.E. Malignant chronic lymphocytic leukemia B cells elaborate soluble factors that down-regulate T cell and NK function. Am. J. Hematol. 1989, 30(2):61-67.
-
(1989)
Am. J. Hematol.
, vol.30
, Issue.2
, pp. 61-67
-
-
Burton, J.D.1
Weitz, C.H.2
Kay, N.E.3
-
95
-
-
0029934177
-
Defective natural killer cell activity in B-cell chronic lymphocytic leukaemia is associated with impaired release of natural killer cytotoxic factor(s) but not of tumour necrosis factor-alpha
-
Katrinakis G., et al. Defective natural killer cell activity in B-cell chronic lymphocytic leukaemia is associated with impaired release of natural killer cytotoxic factor(s) but not of tumour necrosis factor-alpha. Acta Haematol. 1996, 96(1):16-23.
-
(1996)
Acta Haematol.
, vol.96
, Issue.1
, pp. 16-23
-
-
Katrinakis, G.1
-
96
-
-
43749089136
-
NK resistance of tumor cells from multiple myeloma and chronic lymphocytic leukemia patients: implication of HLA-G
-
Maki G., et al. NK resistance of tumor cells from multiple myeloma and chronic lymphocytic leukemia patients: implication of HLA-G. Leukemia 2008, 22(5):998-1006.
-
(2008)
Leukemia
, vol.22
, Issue.5
, pp. 998-1006
-
-
Maki, G.1
-
97
-
-
84859495391
-
4-1BB ligand modulates direct and rituximab-induced NK-cell reactivity in chronic lymphocytic leukemia
-
Buechele C., et al. 4-1BB ligand modulates direct and rituximab-induced NK-cell reactivity in chronic lymphocytic leukemia. Eur. J. Immunol. 2012, 42(3):737-748.
-
(2012)
Eur. J. Immunol.
, vol.42
, Issue.3
, pp. 737-748
-
-
Buechele, C.1
-
98
-
-
77955172722
-
Cord blood natural killer cells exhibit impaired lytic immunological synapse formation that is reversed with IL-2 exvivo expansion
-
Xing D., et al. Cord blood natural killer cells exhibit impaired lytic immunological synapse formation that is reversed with IL-2 exvivo expansion. J. Immunother. 2010, 33(7):684-696.
-
(2010)
J. Immunother.
, vol.33
, Issue.7
, pp. 684-696
-
-
Xing, D.1
-
99
-
-
2542429298
-
Loss of MHC class II gene and protein expression in diffuse large B-cell lymphoma is related to decreased tumor immunosurveillance and poor patient survival regardless of other prognostic factors: a follow-up study from the Leukemia and Lymphoma Molecular Profiling Project
-
Rimsza L.M., et al. Loss of MHC class II gene and protein expression in diffuse large B-cell lymphoma is related to decreased tumor immunosurveillance and poor patient survival regardless of other prognostic factors: a follow-up study from the Leukemia and Lymphoma Molecular Profiling Project. Blood 2004, 103(11):4251-4258.
-
(2004)
Blood
, vol.103
, Issue.11
, pp. 4251-4258
-
-
Rimsza, L.M.1
-
100
-
-
0034669309
-
Extensive genetic alterations of the HLA region, including homozygous deletions of HLA class II genes in B-cell lymphomas arising in immune-privileged sites
-
Riemersma S.A., et al. Extensive genetic alterations of the HLA region, including homozygous deletions of HLA class II genes in B-cell lymphomas arising in immune-privileged sites. Blood 2000, 96(10):3569-3577.
-
(2000)
Blood
, vol.96
, Issue.10
, pp. 3569-3577
-
-
Riemersma, S.A.1
-
101
-
-
79952816655
-
MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers
-
Steidl C., et al. MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers. Nature 2011, 471(7338):377-381.
-
(2011)
Nature
, vol.471
, Issue.7338
, pp. 377-381
-
-
Steidl, C.1
-
102
-
-
84856882081
-
Partial plasma cell differentiation as a mechanism of lost major histocompatibility complex class II expression in diffuse large B-cell lymphoma
-
Wilkinson S.T., et al. Partial plasma cell differentiation as a mechanism of lost major histocompatibility complex class II expression in diffuse large B-cell lymphoma. Blood 2012, 119(6):1459-1467.
-
(2012)
Blood
, vol.119
, Issue.6
, pp. 1459-1467
-
-
Wilkinson, S.T.1
-
103
-
-
83555173561
-
Combined genetic inactivation of beta2-microglobulin and CD58 reveals frequent escape from immune recognition in diffuse large B cell lymphoma
-
Challa-Malladi M., et al. Combined genetic inactivation of beta2-microglobulin and CD58 reveals frequent escape from immune recognition in diffuse large B cell lymphoma. Cancer Cell 2011, 20(6):728-740.
-
(2011)
Cancer Cell
, vol.20
, Issue.6
, pp. 728-740
-
-
Challa-Malladi, M.1
-
104
-
-
0035412359
-
The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis
-
Straus S.E., et al. The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis. Blood 2001, 98(1):194-200.
-
(2001)
Blood
, vol.98
, Issue.1
, pp. 194-200
-
-
Straus, S.E.1
-
105
-
-
0033759326
-
Loss of B7.2 (CD86) and intracellular adhesion molecule 1 (CD54) expression is associated with decreased tumor-infiltrating T lymphocytes in diffuse B-cell large-cell lymphoma
-
Stopeck A.T., et al. Loss of B7.2 (CD86) and intracellular adhesion molecule 1 (CD54) expression is associated with decreased tumor-infiltrating T lymphocytes in diffuse B-cell large-cell lymphoma. Clin. Cancer Res. 2000, 6(10):3904-3909.
-
(2000)
Clin. Cancer Res.
, vol.6
, Issue.10
, pp. 3904-3909
-
-
Stopeck, A.T.1
-
107
-
-
0028927836
-
Failure of B cells of chronic lymphocytic leukemia in presenting soluble and alloantigens
-
Dazzi F., et al. Failure of B cells of chronic lymphocytic leukemia in presenting soluble and alloantigens. Clin. Immunol. Immunopathol. 1995, 75(1):26-32.
-
(1995)
Clin. Immunol. Immunopathol.
, vol.75
, Issue.1
, pp. 26-32
-
-
Dazzi, F.1
-
108
-
-
46749132717
-
Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug
-
Ramsay A.G., et al. Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug. J. Clin. Invest. 2008, 118(7):2427-2437.
-
(2008)
J. Clin. Invest.
, vol.118
, Issue.7
, pp. 2427-2437
-
-
Ramsay, A.G.1
-
109
-
-
73949116990
-
Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy
-
Ramsay A.G., et al. Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy. Blood 2009, 114(21):4713-4720.
-
(2009)
Blood
, vol.114
, Issue.21
, pp. 4713-4720
-
-
Ramsay, A.G.1
-
110
-
-
84878263355
-
Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering rho GTPase signaling that is reversible with lenalidomide
-
Ramsay A.G., et al. Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering rho GTPase signaling that is reversible with lenalidomide. Blood 2013, 121(14):2704-2714.
-
(2013)
Blood
, vol.121
, Issue.14
, pp. 2704-2714
-
-
Ramsay, A.G.1
-
111
-
-
84890531605
-
Follicular lymphoma cells induce changes in T-cell gene expression and function: potential impact on survival and risk of transformation
-
Kiaii S., et al. Follicular lymphoma cells induce changes in T-cell gene expression and function: potential impact on survival and risk of transformation. J. Clin. Oncol. 2013, 31(21):2654-2661.
-
(2013)
J. Clin. Oncol.
, vol.31
, Issue.21
, pp. 2654-2661
-
-
Kiaii, S.1
-
112
-
-
0141672946
-
Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma
-
Rosenwald A., et al. Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma. J Exp Med 2003, 198(6):851-862.
-
(2003)
J Exp Med
, vol.198
, Issue.6
, pp. 851-862
-
-
Rosenwald, A.1
-
113
-
-
78049370405
-
Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma
-
Green M.R., et al. Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma. Blood 2010, 116(17):3268-3277.
-
(2010)
Blood
, vol.116
, Issue.17
, pp. 3268-3277
-
-
Green, M.R.1
-
114
-
-
84858206832
-
Constitutive AP-1 activity and EBV infection induce PD-L1 in Hodgkin lymphomas and posttransplant lymphoproliferative disorders: implications for targeted therapy
-
Green M.R., et al. Constitutive AP-1 activity and EBV infection induce PD-L1 in Hodgkin lymphomas and posttransplant lymphoproliferative disorders: implications for targeted therapy. Clin. Cancer Res. 2012, 18(6):1611-1618.
-
(2012)
Clin. Cancer Res.
, vol.18
, Issue.6
, pp. 1611-1618
-
-
Green, M.R.1
-
115
-
-
44349150012
-
Inhibitory B7-family molecules in the tumour microenvironment
-
Zou W., Chen L. Inhibitory B7-family molecules in the tumour microenvironment. Nat. Rev. Immunol. 2008, 8(6):467-477.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, Issue.6
, pp. 467-477
-
-
Zou, W.1
Chen, L.2
-
116
-
-
80052269038
-
Analysis of the coding genome of diffuse large B-cell lymphoma
-
Pasqualucci L., et al. Analysis of the coding genome of diffuse large B-cell lymphoma. Nat. Genet. 2011, 43(9):830-837.
-
(2011)
Nat. Genet.
, vol.43
, Issue.9
, pp. 830-837
-
-
Pasqualucci, L.1
-
117
-
-
84937780079
-
PD-L1 checkpoint blockade prevents immune dysfunction and leukemia development in a mouse model of chronic lymphocytic leukemia
-
McClanahan F., et al. PD-L1 checkpoint blockade prevents immune dysfunction and leukemia development in a mouse model of chronic lymphocytic leukemia. Blood 2015.
-
(2015)
Blood
-
-
McClanahan, F.1
-
118
-
-
79960318715
-
Programmed death ligand 1 is expressed by non-hodgkin lymphomas and inhibits the activity of tumor-associated T cells
-
Andorsky D.J., et al. Programmed death ligand 1 is expressed by non-hodgkin lymphomas and inhibits the activity of tumor-associated T cells. Clin. Cancer Res. 2011, 17(13):4232-4244.
-
(2011)
Clin. Cancer Res.
, vol.17
, Issue.13
, pp. 4232-4244
-
-
Andorsky, D.J.1
-
119
-
-
0038273853
-
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
-
Curiel T.J., et al. Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nat. Med. 2003, 9(5):562-567.
-
(2003)
Nat. Med.
, vol.9
, Issue.5
, pp. 562-567
-
-
Curiel, T.J.1
-
120
-
-
84928774156
-
The future of immune checkpoint therapy
-
Sharma P., Allison J.P. The future of immune checkpoint therapy. Science 2015, 348(6230):56-61.
-
(2015)
Science
, vol.348
, Issue.6230
, pp. 56-61
-
-
Sharma, P.1
Allison, J.P.2
-
121
-
-
84920956732
-
PD-1 blockade induces responses by inhibiting adaptive immune resistance
-
Tumeh P.C., et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature 2014, 515(7528):568-571.
-
(2014)
Nature
, vol.515
, Issue.7528
, pp. 568-571
-
-
Tumeh, P.C.1
-
122
-
-
84879866976
-
PD-L1 expression is characteristic of a subset of aggressive B-cell lymphomas and virus-associated malignancies
-
Chen B.J., et al. PD-L1 expression is characteristic of a subset of aggressive B-cell lymphomas and virus-associated malignancies. Clin. Cancer Res. 2013, 19(13):3462-3473.
-
(2013)
Clin. Cancer Res.
, vol.19
, Issue.13
, pp. 3462-3473
-
-
Chen, B.J.1
-
123
-
-
84907497893
-
High level of soluble programmed cell death ligand 1 in blood impacts overall survival in aggressive diffuse large B-cell lymphoma: results from a French multicenter clinical trial
-
Rossille D., et al. High level of soluble programmed cell death ligand 1 in blood impacts overall survival in aggressive diffuse large B-cell lymphoma: results from a French multicenter clinical trial. Leukemia 2014, 28(12):2367-2375.
-
(2014)
Leukemia
, vol.28
, Issue.12
, pp. 2367-2375
-
-
Rossille, D.1
-
124
-
-
84880310548
-
Four-year survival rates for patients with metastatic melanoma who received Ipilimumab in phase II clinical trials
-
Wolchok J.D., et al. Four-year survival rates for patients with metastatic melanoma who received Ipilimumab in phase II clinical trials. Ann. Oncol. 2013, 24(8):2174-2180.
-
(2013)
Ann. Oncol.
, vol.24
, Issue.8
, pp. 2174-2180
-
-
Wolchok, J.D.1
-
125
-
-
84924033378
-
Therapeutic antitumor immunity by checkpoint blockade is enhanced by ibrutinib, an inhibitor of both BTK and ITK
-
Sagiv-Barfi I., et al. Therapeutic antitumor immunity by checkpoint blockade is enhanced by ibrutinib, an inhibitor of both BTK and ITK. Proc. Natl. Acad. Sci. U. S. A. 2015, 112(9):E966-E972.
-
(2015)
Proc. Natl. Acad. Sci. U. S. A.
, vol.112
, Issue.9
, pp. E966-E972
-
-
Sagiv-Barfi, I.1
-
126
-
-
84888216911
-
Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes
-
Dubovsky J.A., et al. Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes. Blood 2013, 122(15):2539-2549.
-
(2013)
Blood
, vol.122
, Issue.15
, pp. 2539-2549
-
-
Dubovsky, J.A.1
-
127
-
-
84907680751
-
How does lenalidomide target the chronic lymphocytic leukemia microenvironment?
-
Kater A.P., et al. How does lenalidomide target the chronic lymphocytic leukemia microenvironment?. Blood 2014, 124(14):2184-2189.
-
(2014)
Blood
, vol.124
, Issue.14
, pp. 2184-2189
-
-
Kater, A.P.1
-
128
-
-
84928024740
-
Lenalidomide in non-Hodgkin lymphoma: biological perspectives and therapeutic opportunities
-
Kritharis A., et al. Lenalidomide in non-Hodgkin lymphoma: biological perspectives and therapeutic opportunities. Blood 2015, 125(16):2471-2476.
-
(2015)
Blood
, vol.125
, Issue.16
, pp. 2471-2476
-
-
Kritharis, A.1
-
129
-
-
84892576029
-
Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells
-
Kronke J., et al. Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells. Science 2014, 343(6168):301-305.
-
(2014)
Science
, vol.343
, Issue.6168
, pp. 301-305
-
-
Kronke, J.1
-
130
-
-
84892593087
-
The myeloma drug lenalidomide promotes the cereblon-dependent destruction of ikaros proteins
-
Lu G., et al. The myeloma drug lenalidomide promotes the cereblon-dependent destruction of ikaros proteins. Science 2014, 343(6168):305-309.
-
(2014)
Science
, vol.343
, Issue.6168
, pp. 305-309
-
-
Lu, G.1
-
131
-
-
84894754079
-
Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors ikaros and aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.)
-
Gandhi A.K., et al. Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors ikaros and aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.). Br. J. Haematol. 2014, 164(6):811-821.
-
(2014)
Br. J. Haematol.
, vol.164
, Issue.6
, pp. 811-821
-
-
Gandhi, A.K.1
-
132
-
-
84907047022
-
Lenalidomide inhibits the proliferation of CLL cells via a cereblon/p21(WAF1/Cip1)-dependent mechanism independent of functional p53
-
Fecteau J.F., et al. Lenalidomide inhibits the proliferation of CLL cells via a cereblon/p21(WAF1/Cip1)-dependent mechanism independent of functional p53. Blood 2014, 124(10):1637-1644.
-
(2014)
Blood
, vol.124
, Issue.10
, pp. 1637-1644
-
-
Fecteau, J.F.1
-
133
-
-
84878690962
-
Enhanced cross-priming of naive CD8+ T cells by dendritic cells treated by the IMiDs(R) immunomodulatory compounds lenalidomide and pomalidomide
-
Henry J.Y., et al. Enhanced cross-priming of naive CD8+ T cells by dendritic cells treated by the IMiDs(R) immunomodulatory compounds lenalidomide and pomalidomide. Immunology 2013, 139(3):377-385.
-
(2013)
Immunology
, vol.139
, Issue.3
, pp. 377-385
-
-
Henry, J.Y.1
-
134
-
-
80051928145
-
Treatment with lenalidomide modulates T-cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia
-
Lee B.N., et al. Treatment with lenalidomide modulates T-cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia. Cancer 2011, 117(17):3999-4008.
-
(2011)
Cancer
, vol.117
, Issue.17
, pp. 3999-4008
-
-
Lee, B.N.1
-
135
-
-
84897490051
-
How will B-cell-receptor-targeted therapies change future CLL therapy?
-
Jones J.A., Byrd J.C. How will B-cell-receptor-targeted therapies change future CLL therapy?. Blood 2014, 123(10):1455-1460.
-
(2014)
Blood
, vol.123
, Issue.10
, pp. 1455-1460
-
-
Jones, J.A.1
Byrd, J.C.2
-
136
-
-
84896727745
-
Endothelium-mediated survival of leukemic cells and angiogenesis-related factors are affected by lenalidomide treatment in chronic lymphocytic leukemia
-
e1
-
Maffei R., et al. Endothelium-mediated survival of leukemic cells and angiogenesis-related factors are affected by lenalidomide treatment in chronic lymphocytic leukemia. Exp. Hematol. 2014, 42(2):126-136. e1.
-
(2014)
Exp. Hematol.
, vol.42
, Issue.2
, pp. 126-136
-
-
Maffei, R.1
-
137
-
-
84921764017
-
Lenalidomide combined with R-CHOP overcomes negative prognostic impact of non-germinal center B-cell phenotype in newly diagnosed diffuse large B-cell lymphoma: a phase II study
-
Nowakowski G.S., et al. Lenalidomide combined with R-CHOP overcomes negative prognostic impact of non-germinal center B-cell phenotype in newly diagnosed diffuse large B-cell lymphoma: a phase II study. J. Clin. Oncol. 2015, 33(3):251-257.
-
(2015)
J. Clin. Oncol.
, vol.33
, Issue.3
, pp. 251-257
-
-
Nowakowski, G.S.1
-
138
-
-
0035280238
-
Integrin-associated protein (CD47) and its ligands
-
Brown E.J., Frazier W.A. Integrin-associated protein (CD47) and its ligands. Trends Cell Biol. 2001, 11(3):130-135.
-
(2001)
Trends Cell Biol.
, vol.11
, Issue.3
, pp. 130-135
-
-
Brown, E.J.1
Frazier, W.A.2
-
139
-
-
77953020880
-
Macrophages as mediators of tumor immunosurveillance
-
Jaiswal S., et al. Macrophages as mediators of tumor immunosurveillance. Trends Immunol. 2010, 31(6):212-219.
-
(2010)
Trends Immunol.
, vol.31
, Issue.6
, pp. 212-219
-
-
Jaiswal, S.1
-
140
-
-
67650632683
-
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells
-
Majeti R., et al. CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell 2009, 138(2):286-299.
-
(2009)
Cell
, vol.138
, Issue.2
, pp. 286-299
-
-
Majeti, R.1
-
141
-
-
77956150056
-
Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma
-
Chao M.P., et al. Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma. Cell 2010, 142(5):699-713.
-
(2010)
Cell
, vol.142
, Issue.5
, pp. 699-713
-
-
Chao, M.P.1
-
142
-
-
80855128780
-
Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy
-
Chao M.P., et al. Extranodal dissemination of non-Hodgkin lymphoma requires CD47 and is inhibited by anti-CD47 antibody therapy. Blood 2011, 118(18):4890-4901.
-
(2011)
Blood
, vol.118
, Issue.18
, pp. 4890-4901
-
-
Chao, M.P.1
|