Discovery of a new method for potent drug development using power function of stoichiometry of homomeric biocomplexes or biological nanomotors

Expert Opinion on Drug Delivery

Volumn 13, Issue 1, 2016, Pages 23-36

  Pi, Fengmei ^a,b   Vieweger, Mario ^a,b   Zhao, Zhengyi ^a,b   Wang, Shaoying ^a,b   Guo, Peixuan ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

antibacterial; antivirus; binomial distribution; cancer drug development; drug development; drug target; hexameric ATPase; phi29 dsDNA packaging motor; viral assembly

Indexed keywords

ANTIBIOTIC AGENT; DRUG; ENZYME; G PROTEIN COUPLED RECEPTOR; PURINERGIC P2X7 RECEPTOR; VIRUS DNA;

ARTICLE; BINOMIAL DISTRIBUTION; DNA PACKAGING; DRUG DESIGN; DRUG DEVELOPMENT; DRUG INHIBITION; DRUG POTENCY; DRUG TARGETING; HUMAN; IC50; IN VITRO STUDY; NANOMOTOR; NONHUMAN; STOICHIOMETRY; PHARMACEUTICS; PROCEDURES;

DRUG DESIGN; DRUG DISCOVERY; HUMANS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84955189930     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2015.1082544     Document Type: Article

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