-
2
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646-74.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
80054046029
-
Aerobic glycolysis: Meeting the metabolic requirements of cell proliferation
-
Lunt SY, Vander Heiden MG. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. Annu Rev Cell Dev Biol. 2011;27:441-64.
-
(2011)
Annu Rev Cell Dev Biol
, vol.27
, pp. 441-464
-
-
Lunt, S.Y.1
Vander Heiden, M.G.2
-
4
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science. 1956;123: 309-14.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
5
-
-
33744783432
-
Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance
-
Fantin VR, St-Pierre J, Leder P. Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance. Cancer Cell. 2006;9:425-34.
-
(2006)
Cancer Cell
, vol.9
, pp. 425-434
-
-
Fantin, V.R.1
St-Pierre, J.2
Leder, P.3
-
6
-
-
76649126249
-
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
-
Le A, Cooper CR, Gouw AM, et al. Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression. Proc Nat Acad Sci. 2010;107:2037-42.
-
(2010)
Proc Nat Acad Sci
, vol.107
, pp. 2037-2042
-
-
Le, A.1
Cooper, C.R.2
Gouw, A.M.3
-
7
-
-
33846002728
-
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
-
Bonnet S, Archer SL, Allalunis-Turner J, et al. A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell. 2007;11:37-51.
-
(2007)
Cancer Cell
, vol.11
, pp. 37-51
-
-
Bonnet, S.1
Archer, S.L.2
Allalunis-Turner, J.3
-
8
-
-
84877771859
-
Evaluation of mitochondrial function and metabolic reprogramming during tumor progression in a cell model of skin carcinogenesis
-
Jan 22, [Epub ahead of print]
-
Vallejo CG, Cruz-Bermúdez A, Clemente P, et al. Evaluation of mitochondrial function and metabolic reprogramming during tumor progression in a cell model of skin carcinogenesis. Biochimie. 2013 Jan 22. [Epub ahead of print]
-
(2013)
Biochimie
-
-
Vallejo, C.G.1
Cruz-Bermúdez, A.2
Clemente, P.3
-
9
-
-
37449034854
-
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
DeBerardinis RJ, Mancuso A, Daikhin E, et al. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Nat Acad Sci. 2007;104:19345-50.
-
(2007)
Proc Nat Acad Sci
, vol.104
, pp. 19345-19350
-
-
Deberardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
-
10
-
-
79955398591
-
Otto Warburgs contributions to current concepts of cancer metabolism
-
Koppenol W H, Bounds PL, Dang CV. Otto Warburgs contributions to current concepts of cancer metabolism. Nature Rev Cancer. 2011;11:325-37.
-
(2011)
Nature Rev Cancer
, vol.11
, pp. 325-337
-
-
Koppenol, W.H.1
Bounds, P.L.2
Dang, C.V.3
-
11
-
-
84858604270
-
Metabolic reprogramming: A cancer hallmark even Warburg did not anticipate
-
Ward PS, Thompson CB. Metabolic reprogramming: a cancer hallmark even Warburg did not anticipate. Cancer Cell. 2012;21:297-308.
-
(2012)
Cancer Cell
, vol.21
, pp. 297-308
-
-
Ward, P.S.1
Thompson, C.B.2
-
13
-
-
0032788570
-
Acidic environment causes apoptosis by increasing caspase activity
-
Park HJ, Lyons JC, Ohtsubo T, Song CW. Acidic environment causes apoptosis by increasing caspase activity. Br J Cancer. 1999;80:1892.
-
(1999)
Br J Cancer
, vol.80
, pp. 1892
-
-
Park, H.J.1
Lyons, J.C.2
Ohtsubo, T.3
Song, C.W.4
-
14
-
-
0033609365
-
An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carinoma cell lines: Implications for clonal selection during colorectal carcinogenesis
-
Williams AC, Collard TJ, Paraskeva C. An acidic environment leads to p53 dependent induction of apoptosis in human adenoma and carinoma cell lines: Implications for clonal selection during colorectal carcinogenesis. Oncogene. 1999;18:3199-204.
-
(1999)
Oncogene
, vol.18
, pp. 3199-3204
-
-
Williams, A.C.1
Collard, T.J.2
Paraskeva, C.3
-
15
-
-
0026568374
-
Variations in tumor cell growth rates and metabolism with oxygen concentration, glucose concentration, and extracellular pH
-
Casciari JJ, Sotirchos SV, Sutherland RM. Variations in tumor cell growth rates and metabolism with oxygen concentration, glucose concentration, and extracellular pH. J Cell Physiol. 2005;151:386-94.
-
(2005)
J Cell Physiol
, vol.151
, pp. 386-394
-
-
Casciari, J.J.1
Sotirchos, S.V.2
Sutherland, R.M.3
-
16
-
-
0042242676
-
The glycolytic phenotype in carcinogenesis and tumor invasion insights through mathematical models
-
Gatenby RA, Gawlinski ET. The glycolytic phenotype in carcinogenesis and tumor invasion insights through mathematical models. Cancer Res. 2003;63:3847-54.
-
(2003)
Cancer Res
, vol.63
, pp. 3847-3854
-
-
Gatenby, R.A.1
Gawlinski, E.T.2
-
17
-
-
84872548105
-
PDK1 inhibition is a novel therapeutic target in multiple myeloma
-
Fujiwara S, Kawano Y, Yuki H, et al. PDK1 inhibition is a novel therapeutic target in multiple myeloma. Br J Cancer. 2012;108:170-8.
-
(2012)
Br J Cancer
, vol.108
, pp. 170-178
-
-
Fujiwara, S.1
Kawano, Y.2
Yuki, H.3
-
18
-
-
0034698178
-
Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc
-
Osthus RC, Shim H, Kim S, et al. Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc. J Biol Chem. 2000;275:21797-800.
-
(2000)
J Biol Chem
, vol.275
, pp. 21797-21800
-
-
Osthus, R.C.1
Shim, H.2
Kim, S.3
-
19
-
-
50149097983
-
Hypoxia, HIF1 and glucose metabolism in the solid tumour
-
Denko NC. Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nature Rev Cancer. 2008;8:705-13.
-
(2008)
Nature Rev Cancer
, vol.8
, pp. 705-713
-
-
Denko, N.C.1
-
20
-
-
57649130593
-
Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance
-
Lu CW, Lin SC, Chen KF, et al. Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance. J Biol Chem. 2008;283:28106-14.
-
(2008)
J Biol Chem
, vol.283
, pp. 28106-28114
-
-
Lu, C.W.1
Lin, S.C.2
Chen, K.F.3
-
21
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
Christofk HR, Vander Heiden MG, Harris MH, et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature. 2008;452:230-3.
-
(2008)
Nature
, vol.452
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
-
22
-
-
33746924468
-
Hexokinase II: Cancers double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria
-
Mathupala SP, Ko YH, Pedersen PL. Hexokinase II: cancers double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria. Oncogene. 2006;25:4777-86.
-
(2006)
Oncogene
, vol.25
, pp. 4777-4786
-
-
Mathupala, S.P.1
Ko, Y.H.2
Pedersen, P.L.3
-
23
-
-
48549088300
-
The Warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation
-
Samudio I, Fiegl M, McQueen T, et al. The Warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation. Cancer Res. 2008;68: 5198-205.
-
(2008)
Cancer Res
, vol.68
, pp. 5198-5205
-
-
Samudio, I.1
Fiegl, M.2
McQueen, T.3
-
24
-
-
0041357164
-
BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis
-
Danial NN, Gramm CF, Scorrano L, et al. BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis. Nature. 2003;424:952-6.
-
(2003)
Nature
, vol.424
, pp. 952-956
-
-
Danial, N.N.1
Gramm, C.F.2
Scorrano, L.3
-
25
-
-
0141863388
-
Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival
-
Rathmell JC, Fox CJ, Plas DR, et al. Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival. Mol Cell Biol. 2003;23:7315-28.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7315-7328
-
-
Rathmell, J.C.1
Fox, C.J.2
Plas, D.R.3
-
26
-
-
75149129097
-
The prognostic value of F-18 fluorodeoxyglucose bone marrow uptake in patients with recent diagnosis of multiple myeloma: A comparative study with Tc-99m sestamibi
-
Castellani M, Carletto M, Baldini L, et al. The prognostic value of F-18 fluorodeoxyglucose bone marrow uptake in patients with recent diagnosis of multiple myeloma: a comparative study with Tc-99m sestamibi. Clin Nucl Med. 2010;35:1.
-
(2010)
Clin Nucl Med
, vol.35
, pp. 1
-
-
Castellani, M.1
Carletto, M.2
Baldini, L.3
-
27
-
-
82955189267
-
Prognostic relevance of 18-F FDG PET/CT in newly diagnosed multiple myeloma patients treated with up-front autologous transplantation
-
Zamagni E, Patriarca F, Nanni C, et al. Prognostic relevance of 18-F FDG PET/CT in newly diagnosed multiple myeloma patients treated with up-front autologous transplantation. Blood. 2011;118:5989-95.
-
(2011)
Blood
, vol.118
, pp. 5989-5995
-
-
Zamagni, E.1
Patriarca, F.2
Nanni, C.3
-
28
-
-
70349231349
-
F18-fluorodeoxyglucose positron emission tomography in the context of other imaging techniques and prognostic factors in multiple myeloma
-
Bartel TB, Haessler J, Brown TL, et al. F18-fluorodeoxyglucose positron emission tomography in the context of other imaging techniques and prognostic factors in multiple myeloma. Blood. 2009;114:2068-76.
-
(2009)
Blood
, vol.114
, pp. 2068-2076
-
-
Bartel, T.B.1
Haessler, J.2
Brown, T.L.3
-
29
-
-
84866274799
-
Fasting enhances the response of glioma to chemo- and radiotherapy
-
Safdie F, Brandhorst S, Wei M, et al. Fasting enhances the response of glioma to chemo- and radiotherapy. PloS One. 2012;7:e44603.
-
(2012)
PloS One
, vol.7
-
-
Safdie, F.1
Brandhorst, S.2
Wei, M.3
-
30
-
-
84863229916
-
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy
-
Lee C, Raffaghello L, Brandhorst S, et al. Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy. Sci Transl Med. 2012;4:124-27.
-
(2012)
Sci Transl Med
, vol.4
, pp. 124-127
-
-
Lee, C.1
Raffaghello, L.2
Brandhorst, S.3
-
31
-
-
0037056002
-
Mitochondrial bound type II hexokinase: A key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention
-
Pedersen PL, Mathupala S, Rempel A, et al. Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention. Biochim Biophys Acta. 2002;1555:14-20.
-
(2002)
Biochim Biophys Acta
, vol.1555
, pp. 14-20
-
-
Pedersen, P.L.1
Mathupala, S.2
Rempel, A.3
-
32
-
-
0037108709
-
High expression of inducible 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (iPFK-2; PFKFB3) in human cancers
-
Atsumi T, Chesney J, Metz C, et al. High expression of inducible 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase (iPFK-2; PFKFB3) in human cancers. Cancer Res. 2002;62:5881-7.
-
(2002)
Cancer Res
, vol.62
, pp. 5881-5887
-
-
Atsumi, T.1
Chesney, J.2
Metz, C.3
-
33
-
-
84860389289
-
Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
-
Grassian AR, Metallo CM, Coloff JL, et al. Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation. Sci Signal. 2011;25:1716.
-
(2011)
Sci Signal
, vol.25
, pp. 1716
-
-
Grassian, A.R.1
Metallo, C.M.2
Coloff, J.L.3
-
34
-
-
84856913587
-
Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression
-
Goldberg MS, Sharp PA. Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression. J Exp Med. 2012;209:217-24.
-
(2012)
J Exp Med
, vol.209
, pp. 217-224
-
-
Goldberg, M.S.1
Sharp, P.A.2
-
35
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
Christofk HR, Vander Heiden MG, Harris MH, et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature. 2008;452:230-3.
-
(2008)
Nature
, vol.452
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
-
36
-
-
84870598190
-
ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
-
Yang W, Zheng Y, Xia Y, et al. ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect. Nature Cell Biol. 2012;14:1295-304.
-
(2012)
Nature Cell Biol
, vol.14
, pp. 1295-1304
-
-
Yang, W.1
Zheng, Y.2
Xia, Y.3
-
37
-
-
0037108676
-
Time to progression in metastatic breast cancer patients treated with epirubicin is not improved by the addition of either cisplatin or lonidamine: Final results of a phase III study with a factorial design
-
Berruti A, Bitossi R, Gorzegno G, et al. Time to progression in metastatic breast cancer patients treated with epirubicin is not improved by the addition of either cisplatin or lonidamine: final results of a phase III study with a factorial design. J Clin Oncol. 2002;20:4150-9.
-
(2002)
J Clin Oncol
, vol.20
, pp. 4150-4159
-
-
Berruti, A.1
Bitossi, R.2
Gorzegno, G.3
-
38
-
-
34250179496
-
Combining radioimmunotherapy with antihypoxia therapy 2-deoxy-D-glucose results in reduction of therapeutic efficacy
-
Dearling JL, Qureshi U, Begent RH, Pedley RB. Combining radioimmunotherapy with antihypoxia therapy 2-deoxy-D-glucose results in reduction of therapeutic efficacy. Clin Cancer Res. 2007;13:1903-10.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1903-1910
-
-
Dearling, J.L.1
Qureshi, U.2
Begent, R.H.3
Pedley, R.B.4
-
39
-
-
41549113465
-
Synergistic antipancreatic tumor effect by simultaneously targeting hypoxic cancer cells with HSP90 inhibitor and glycolysis inhibitor
-
Cao X, Bloomston M, Zhang T, et al. Synergistic antipancreatic tumor effect by simultaneously targeting hypoxic cancer cells with HSP90 inhibitor and glycolysis inhibitor. Clin Cancer Res. 2008;14:1831-9.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1831-1839
-
-
Cao, X.1
Bloomston, M.2
Zhang, T.3
-
40
-
-
0022595453
-
Hexokinase receptor complex in hepatoma mitochondria: Evidence from N, N-dicyclohexlycarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC
-
Nakashima RA, Mangan PS, Colombini M, Pedersen PL. Hexokinase receptor complex in hepatoma mitochondria: evidence from N, N-dicyclohexlycarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC. Biochemistry. 1986;25:1015-21.
-
(1986)
Biochemistry
, vol.25
, pp. 1015-1021
-
-
Nakashima, R.A.1
Mangan, P.S.2
Colombini, M.3
Pedersen, P.L.4
-
41
-
-
84869082905
-
Serine is a natural ligand and allosteric activator of pyruvate kinase M2
-
Chaneton B, Hillmann P, Zheng L, et al. Serine is a natural ligand and allosteric activator of pyruvate kinase M2. Nature. 2012;491:458-62.
-
(2012)
Nature
, vol.491
, pp. 458-462
-
-
Chaneton, B.1
Hillmann, P.2
Zheng, L.3
-
42
-
-
80052258995
-
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
-
Locasale JW, Grassian AR, Melman T, et al. Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nat Genet. 2011;43:869-74.
-
(2011)
Nat Genet
, vol.43
, pp. 869-874
-
-
Locasale, J.W.1
Grassian, A.R.2
Melman, T.3
-
43
-
-
84867097473
-
Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma
-
Sheng SL, Liu JJ, Dai YH, et al. Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma. FEBSJ. 2012;279:3898-910.
-
(2012)
FEBSJ
, vol.279
, pp. 3898-3910
-
-
Sheng, S.L.1
Liu, J.J.2
Dai, Y.H.3
-
45
-
-
79961215490
-
Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality
-
Chan DA, Sutphin PD, Nguyen P, et al. Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality. Sci Translat Med. 2011; 3:94-70.
-
(2011)
Sci Translat Med
, vol.3
, pp. 94-170
-
-
Chan, D.A.1
Sutphin, P.D.2
Nguyen, P.3
-
46
-
-
0034617191
-
The mechanism of insulin resistance caused by HIV protease inhibitor therapy
-
Murata H, Hruz PW, Mueckler M. The mechanism of insulin resistance caused by HIV protease inhibitor therapy. Sci Signal. 2000;275:20251.
-
(2000)
Sci Signal
, vol.275
, pp. 20251
-
-
Murata, H.1
Hruz, P.W.2
Mueckler, M.3
-
47
-
-
78449233456
-
Effects of the HIV protease inhibitor ritonavir on GLUT4 knock-out mice
-
Vyas AK, Koste, JC, Tzekov A, Hruz PW. Effects of the HIV protease inhibitor ritonavir on GLUT4 knock-out mice. J Biol Chem. 2010;285:36395-400.
-
(2010)
J Biol Chem
, vol.285
, pp. 36395-36400
-
-
Vyas, A.K.1
Koste, J.C.2
Tzekov, A.3
Hruz, P.W.4
-
48
-
-
84861215287
-
Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: Implications for glucose transporter-directed therapy
-
McBrayer SK, Cheng JC, Singhal S, et al. Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy. Blood. 2012;119:4686-97.
-
(2012)
Blood
, vol.119
, pp. 4686-4697
-
-
McBrayer, S.K.1
Cheng, J.C.2
Singhal, S.3
-
49
-
-
0015288919
-
The role of glutamine in the oxidative metabolism of malignant cells
-
Kovaevi K, Morris HP. The role of glutamine in the oxidative metabolism of malignant cells. Cancer Res. 1972;32:326-33.
-
(1972)
Cancer Res
, vol.32
, pp. 326-333
-
-
Kovaevi, K.1
Morris, H.P.2
-
50
-
-
70350217425
-
Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling
-
Yang C, Sudderth J, Dang T, et al. Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling. Cancer Res. 2009;69: 7986-93.
-
(2009)
Cancer Res
, vol.69
, pp. 7986-7993
-
-
Yang, C.1
Sudderth, J.2
Dang, T.3
-
51
-
-
84895071300
-
Control of glutamine metabolism by the tumor suppressor Rb
-
Jan 28. [Epub ahead of print]
-
Reynolds MR, Lane AN, Robertson B, et al. Control of glutamine metabolism by the tumor suppressor Rb. Oncogene. 2013 Jan 28. [Epub ahead of print]
-
(2013)
Oncogene
-
-
Reynolds, M.R.1
Lane, A.N.2
Robertson, B.3
-
52
-
-
33645766204
-
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin
-
Bowker SL, Majumdar SR, Veugelers P, Johnson JA. Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin. Diabetes Care. 2006;29:254-8.
-
(2006)
Diabetes Care
, vol.29
, pp. 254-258
-
-
Bowker, S.L.1
Majumdar, S.R.2
Veugelers, P.3
Johnson, J.A.4
-
53
-
-
12144291275
-
Thiazo lidinediones, like metformin, inhibit respiratory complex IA common mechanism contributing to their antidiabetic actions?
-
Brunmair B, Staniek K, Gras F, et al. Thiazo lidinediones, like metformin, inhibit respiratory complex IA common mechanism contributing to their antidiabetic actions? Diabetes. 2004;53:1052-9.
-
(2004)
Diabetes
, vol.53
, pp. 1052-1059
-
-
Brunmair, B.1
Staniek, K.2
Gras, F.3
-
54
-
-
77956415337
-
Metformin prevents tobacco carcinogeninduced lung tumorigenesis
-
Memmott RM, Mercado JR, Maier CR, et al. Metformin prevents tobacco carcinogeninduced lung tumorigenesis. Cancer Prev Res. 2010;3:1066-76.
-
(2010)
Cancer Prev Res
, vol.3
, pp. 1066-1076
-
-
Memmott, R.M.1
Mercado, J.R.2
Maier, C.R.3
-
55
-
-
74549131244
-
Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo
-
Anisimov VN, Egormin PA, Piskunova TS, et al. Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo. Cell Cycle. 2010;9:188-97.
-
(2010)
Cell Cycle
, vol.9
, pp. 188-197
-
-
Anisimov, V.N.1
Egormin, P.A.2
Piskunova, T.S.3
-
56
-
-
84862908866
-
Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers
-
Deng XS, Wang S, Deng A, et al. Metformin targets Stat3 to inhibit cell growth and induce apoptosis in triple-negative breast cancers. Cell Cycle. 2012;11:367-76.
-
(2012)
Cell Cycle
, vol.11
, pp. 367-376
-
-
Deng, X.S.1
Wang, S.2
Deng, A.3
-
57
-
-
75249094454
-
Calorie restriction and cancer prevention: Metabolic and molecular mechanisms
-
Longo VD, Fontana L. Calorie restriction and cancer prevention: metabolic and molecular mechanisms. Trends Pharm Sci. 2010;31:89-98.
-
(2010)
Trends Pharm Sci
, vol.31
, pp. 89-98
-
-
Longo, V.D.1
Fontana, L.2
|