메뉴 건너뛰기




Volumn 7, Issue 1, 2008, Pages 38-47

Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; PROTEIN KINASE B; SURVIVIN; TRASTUZUMAB; X LINKED INHIBITOR OF APOPTOSIS;

EID: 38349155799     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-07-0370     Document Type: Article
Times cited : (61)

References (50)
  • 1
    • 0001512931 scopus 로고
    • Inflammatory carcinoma of the breast: A report of twenty-eight cases from the breast clinic of Memorial Hospital
    • Lee B, Tannenbaum N. Inflammatory carcinoma of the breast: a report of twenty-eight cases from the breast clinic of Memorial Hospital. Surg Gynecol Obstet 1924;39:580-95.
    • (1924) Surg Gynecol Obstet , vol.39 , pp. 580-595
    • Lee, B.1    Tannenbaum, N.2
  • 2
    • 0037811710 scopus 로고    scopus 로고
    • Inflammatory breast carcinoma and noninflammatory locally advanced breast carcinoma: Distinct clinicopathologic entities
    • Anderson WF, Chu KC, Chang S. Inflammatory breast carcinoma and noninflammatory locally advanced breast carcinoma: distinct clinicopathologic entities. J Clin Oncol 2003;21:2254-9.
    • (2003) J Clin Oncol , vol.21 , pp. 2254-2259
    • Anderson, W.F.1    Chu, K.C.2    Chang, S.3
  • 3
    • 0018854657 scopus 로고
    • Inflammatory breast carcinoma treated by radical radiotherapy
    • Chu AM, Wood WC, Doucette JA. Inflammatory breast carcinoma treated by radical radiotherapy. Cancer 1980;45:2730-7.
    • (1980) Cancer , vol.45 , pp. 2730-2737
    • Chu, A.M.1    Wood, W.C.2    Doucette, J.A.3
  • 4
    • 0022860622 scopus 로고
    • Primary chemotherapy in the treatment of inflammatory breast carcinoma: A study of 230 cases from the Institut Gustave-Roussy
    • Rouesse J, Friedman S, Sarrazin D, et al. Primary chemotherapy in the treatment of inflammatory breast carcinoma: a study of 230 cases from the Institut Gustave-Roussy. J Clin Oncol 1986;4:1765-71.
    • (1986) J Clin Oncol , vol.4 , pp. 1765-1771
    • Rouesse, J.1    Friedman, S.2    Sarrazin, D.3
  • 5
    • 12144286354 scopus 로고    scopus 로고
    • Validation of a tissue microarray to study differential protein expression in inflammatory and non-inflammatory breast cancer
    • Van den Eynden GG, Van der Auwera I, Van Laere S, et al. Validation of a tissue microarray to study differential protein expression in inflammatory and non-inflammatory breast cancer. Breast Cancer Res Treat 2004;85:13-22.
    • (2004) Breast Cancer Res Treat , vol.85 , pp. 13-22
    • Van den Eynden, G.G.1    Van der Auwera, I.2    Van Laere, S.3
  • 6
    • 0029693908 scopus 로고    scopus 로고
    • Review of known prognostic variables
    • Kaufmann M. Review of known prognostic variables. Recent Results Cancer Res 1996;140:77-87.
    • (1996) Recent Results Cancer Res , vol.140 , pp. 77-87
    • Kaufmann, M.1
  • 7
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987;235:177-82.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 8
    • 4143114773 scopus 로고    scopus 로고
    • Long-term follow-up for inflammatory (IBC) and non-inflammatory (NIBC) stage III breast cancer patients treated with combination chemotherapy
    • Low JA, Berman AW, Steinberg SM. Long-term follow-up for inflammatory (IBC) and non-inflammatory (NIBC) stage III breast cancer patients treated with combination chemotherapy. Proc Am Soc Clin Oncol 2002;21:63a.
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Low, J.A.1    Berman, A.W.2    Steinberg, S.M.3
  • 9
    • 21244466004 scopus 로고    scopus 로고
    • Trends in inflammatory breast carcinoma incidence and survival: The Surveillance, Epidemiology, and End Results Program at the National Cancer Institute
    • Hance KW, Anderson WF, Devesa SS, Young HA, Levine PH. Trends in inflammatory breast carcinoma incidence and survival: the Surveillance, Epidemiology, and End Results Program at the National Cancer Institute. J Natl Cancer Inst 2005;97:966-75.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 966-975
    • Hance, K.W.1    Anderson, W.F.2    Devesa, S.S.3    Young, H.A.4    Levine, P.H.5
  • 10
    • 0024263357 scopus 로고
    • Management of stage III primary breast cancer with primary chemotherapy, surgery, and radiation therapy
    • Hortobagyi GN, Ames FC, Buzdar AU, et al. Management of stage III primary breast cancer with primary chemotherapy, surgery, and radiation therapy. Cancer 1988;62:2507-16.
    • (1988) Cancer , vol.62 , pp. 2507-2516
    • Hortobagyi, G.N.1    Ames, F.C.2    Buzdar, A.U.3
  • 11
    • 18844470858 scopus 로고    scopus 로고
    • Breast conservation and prolonged chemotherapy for locally advanced breast cancer: The University of Michigan experience
    • Merajver SD, Weber BL, Cody R, et al. Breast conservation and prolonged chemotherapy for locally advanced breast cancer: the University of Michigan experience. J Clin Oncol 1997;15:2873-81.
    • (1997) J Clin Oncol , vol.15 , pp. 2873-2881
    • Merajver, S.D.1    Weber, B.L.2    Cody, R.3
  • 12
    • 18344390418 scopus 로고    scopus 로고
    • ERBB receptors and cancer: The complexity of targeted inhibitors
    • Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer 2005;5:341-54.
    • (2005) Nat Rev Cancer , vol.5 , pp. 341-354
    • Hynes, N.E.1    Lane, H.A.2
  • 13
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressingmetastati c breast cancer that has progressed after chemotherapy for metastatic disease
    • Cobleigh MA, Vogel CL, Tripathy D, et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressingmetastati c breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999;17:2639-48.
    • (1999) J Clin Oncol , vol.17 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3
  • 14
    • 0036467826 scopus 로고    scopus 로고
    • Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
    • Vogel CL, Cobleigh MA, Tripathy D, et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol 2002;20:719-26.
    • (2002) J Clin Oncol , vol.20 , pp. 719-726
    • Vogel, C.L.1    Cobleigh, M.A.2    Tripathy, D.3
  • 15
    • 31644439702 scopus 로고    scopus 로고
    • Herceptin: Mechanisms of action and resistance
    • Nahta R, Esteva FJ. Herceptin: mechanisms of action and resistance. Cancer Lett 2006;232:123-38.
    • (2006) Cancer Lett , vol.232 , pp. 123-138
    • Nahta, R.1    Esteva, F.J.2
  • 16
    • 33646712747 scopus 로고    scopus 로고
    • Mechanisms of disease: Understandingresist ance to HER2-targeted therapy in human breast cancer
    • Nahta R, Yu D, Hung MC, Hortobagyi GN, Esteva FJ. Mechanisms of disease: understandingresist ance to HER2-targeted therapy in human breast cancer. Nat Clin Pract Oncol 2006;3:269-80.
    • (2006) Nat Clin Pract Oncol , vol.3 , pp. 269-280
    • Nahta, R.1    Yu, D.2    Hung, M.C.3    Hortobagyi, G.N.4    Esteva, F.J.5
  • 17
    • 23944476155 scopus 로고    scopus 로고
    • Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas
    • Burris HA III, Hurwitz HI, Dees EC, et al. Phase I safety, pharmacokinetics, and clinical activity study of lapatinib (GW572016), a reversible dual inhibitor of epidermal growth factor receptor tyrosine kinases, in heavily pretreated patients with metastatic carcinomas. J Clin Oncol 2005;23:5305-13.
    • (2005) J Clin Oncol , vol.23 , pp. 5305-5313
    • Burris III, H.A.1    Hurwitz, H.I.2    Dees, E.C.3
  • 18
    • 32944461545 scopus 로고    scopus 로고
    • Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells
    • Konecny GE, Pegram MD, Venkatesan N, et al. Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells. Cancer Res 2006;66:1630-9.
    • (2006) Cancer Res , vol.66 , pp. 1630-1639
    • Konecny, G.E.1    Pegram, M.D.2    Venkatesan, N.3
  • 19
    • 20244388653 scopus 로고    scopus 로고
    • Study of the biologic effects of lapatinib, a reversible inhibitor of ErbB1 and ErbB2 tyrosine kinases, on tumor growth and survival pathways in patients with advanced malignancies
    • Spector NL, Xia W, Burris H III, et al. Study of the biologic effects of lapatinib, a reversible inhibitor of ErbB1 and ErbB2 tyrosine kinases, on tumor growth and survival pathways in patients with advanced malignancies. J Clin Oncol 2005;23:2502-12.
    • (2005) J Clin Oncol , vol.23 , pp. 2502-2512
    • Spector, N.L.1    Xia, W.2    Burris III, H.3
  • 20
    • 33747125264 scopus 로고    scopus 로고
    • EGF103009, a phase II trial of lapatinib monotherapy in patients with relapsed/refractory inflammatory breast cancer (IBC): Clinical activity and biologic predictors of response
    • Atlanta GA
    • Spector NL, Blackwell K, Hurley J, et al. EGF103009, a phase II trial of lapatinib monotherapy in patients with relapsed/refractory inflammatory breast cancer (IBC): clinical activity and biologic predictors of response. ASCO Annual Meeting, 2006. Atlanta (GA); 2006. p. 502.
    • (2006) ASCO Annual Meeting , pp. 502
    • Spector, N.L.1    Blackwell, K.2    Hurley, J.3
  • 21
    • 0035902115 scopus 로고    scopus 로고
    • Proliferation, cell cycle and apoptosis in cancer
    • Evan GI, Vousden KH. Proliferation, cell cycle and apoptosis in cancer. Nature 2001;411:342-8.
    • (2001) Nature , vol.411 , pp. 342-348
    • Evan, G.I.1    Vousden, K.H.2
  • 22
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 23
    • 2342544675 scopus 로고    scopus 로고
    • XIAP as target for therapeutic apoptosis in prostate cancer
    • Devi GR. XIAP as target for therapeutic apoptosis in prostate cancer. Drug News Perspect 2004;17:127-34.
    • (2004) Drug News Perspect , vol.17 , pp. 127-134
    • Devi, G.R.1
  • 24
    • 0346880501 scopus 로고    scopus 로고
    • The inhibitors of apoptosis: There is more to life than Bcl2
    • Liston P, Fong WG, Korneluk RG. The inhibitors of apoptosis: there is more to life than Bcl2. Oncogene 2003;22:8568-80.
    • (2003) Oncogene , vol.22 , pp. 8568-8580
    • Liston, P.1    Fong, W.G.2    Korneluk, R.G.3
  • 25
    • 28244490602 scopus 로고    scopus 로고
    • Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells
    • Asanuma H, Torigoe T, Kamiguchi K, et al. Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells. Cancer Res 2005;65:11018-25.
    • (2005) Cancer Res , vol.65 , pp. 11018-11025
    • Asanuma, H.1    Torigoe, T.2    Kamiguchi, K.3
  • 26
    • 9344244740 scopus 로고    scopus 로고
    • Trastuzumab down-regulates Bcl-2 expression and potentiates apoptosis induction by Bcl-2/Bcl-XL bispecific antisense oligonucleotides in HER-2 gene-amplified breast cancer cells
    • Milella M, Trisciuoglio D, Bruno T, et al. Trastuzumab down-regulates Bcl-2 expression and potentiates apoptosis induction by Bcl-2/Bcl-XL bispecific antisense oligonucleotides in HER-2 gene-amplified breast cancer cells. Clin Cancer Res 2004;10:7747-56.
    • (2004) Clin Cancer Res , vol.10 , pp. 7747-7756
    • Milella, M.1    Trisciuoglio, D.2    Bruno, T.3
  • 27
    • 33749012842 scopus 로고    scopus 로고
    • Molecular heterogeneity of inflammatory breast cancer: A hyperproliferative phenotype
    • Nguyen DM, Sam K, Tsimelzon A, et al. Molecular heterogeneity of inflammatory breast cancer: a hyperproliferative phenotype. Clin Cancer Res 2006;12:5047-54.
    • (2006) Clin Cancer Res , vol.12 , pp. 5047-5054
    • Nguyen, D.M.1    Sam, K.2    Tsimelzon, A.3
  • 28
    • 33646746413 scopus 로고    scopus 로고
    • A model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancer
    • Xia W, Bacus S, Hegde P, et al. A model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancer. Proc Natl Acad Sci U S A 2006;103:7795-800.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 7795-7800
    • Xia, W.1    Bacus, S.2    Hegde, P.3
  • 29
    • 32944460139 scopus 로고    scopus 로고
    • Regulation of survivin by ErbB2 signaling: Therapeutic implications for ErbB2-overexpressingbreas t cancers
    • Xia W, Bisi J, Strum J, et al. Regulation of survivin by ErbB2 signaling: therapeutic implications for ErbB2-overexpressingbreas t cancers. Cancer Res 2006;66:1640-7.
    • (2006) Cancer Res , vol.66 , pp. 1640-1647
    • Xia, W.1    Bisi, J.2    Strum, J.3
  • 30
    • 0032760412 scopus 로고    scopus 로고
    • Molecular cytogenetic analysis of 11 new breast cancer cell lines
    • Forozan F, Veldman R, Ammerman CA, et al. Molecular cytogenetic analysis of 11 new breast cancer cell lines. Br J Cancer 1999;81:1328-34.
    • (1999) Br J Cancer , vol.81 , pp. 1328-1334
    • Forozan, F.1    Veldman, R.2    Ammerman, C.A.3
  • 31
    • 4444280830 scopus 로고    scopus 로고
    • X-linked inhibitor of apoptosis protein inhibition induces apoptosis and enhances chemotherapy sensitivity in human prostate cancer cells
    • Amantana A, London CA, Iversen PL, Devi GR. X-linked inhibitor of apoptosis protein inhibition induces apoptosis and enhances chemotherapy sensitivity in human prostate cancer cells. Mol Cancer Ther 2004;3:699-707.
    • (2004) Mol Cancer Ther , vol.3 , pp. 699-707
    • Amantana, A.1    London, C.A.2    Iversen, P.L.3    Devi, G.R.4
  • 32
    • 22244453690 scopus 로고    scopus 로고
    • Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2
    • Longva KE, Pedersen NM, Haslekas C, Stang E, Madshus IH. Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2. Int J Cancer 2005;116:359-67.
    • (2005) Int J Cancer , vol.116 , pp. 359-367
    • Longva, K.E.1    Pedersen, N.M.2    Haslekas, C.3    Stang, E.4    Madshus, I.H.5
  • 33
    • 0034565927 scopus 로고    scopus 로고
    • Radiosensitization of human breast cancer cells by a novel ErbB family receptor tyrosine kinase inhibitor
    • Rao GS, Murray S, Ethier SP. Radiosensitization of human breast cancer cells by a novel ErbB family receptor tyrosine kinase inhibitor. Int J Radiat Oncol Biol Phys 2000;48:1519-28.
    • (2000) Int J Radiat Oncol Biol Phys , vol.48 , pp. 1519-1528
    • Rao, G.S.1    Murray, S.2    Ethier, S.P.3
  • 34
    • 0035915421 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin)
    • Lu Y, Zi X, Zhao Y, Mascarenhas D, Pollak M. Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). J Natl Cancer Inst 2001;93:1852-7.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1852-1857
    • Lu, Y.1    Zi, X.2    Zhao, Y.3    Mascarenhas, D.4    Pollak, M.5
  • 35
    • 30544450275 scopus 로고    scopus 로고
    • Combininglapati nib (GW572016), a small molecule inhibitor of ErbB1 and ErbB2 tyrosine kinases, with therapeutic anti-ErbB2 antibodies enhances apoptosis of ErbB2-overexpressingbreast cancer cells
    • Xia W, Gerard CM, Liu L, Baudson NM, Ory TL, Spector NL. Combininglapati nib (GW572016), a small molecule inhibitor of ErbB1 and ErbB2 tyrosine kinases, with therapeutic anti-ErbB2 antibodies enhances apoptosis of ErbB2-overexpressingbreast cancer cells. Oncogene 2005;24:6213-21.
    • (2005) Oncogene , vol.24 , pp. 6213-6221
    • Xia, W.1    Gerard, C.M.2    Liu, L.3    Baudson, N.M.4    Ory, T.L.5    Spector, N.L.6
  • 36
    • 0942268145 scopus 로고    scopus 로고
    • Effects of the EGFR/HER2 kinase inhibitor GW572016 on EGFR- and HER2-overexpressing breast cancer cell line proliferation, radiosensitization, and resistance
    • Zhou H, Kim YS, Peletier A, McCall W, Earp HS, Sartor CI. Effects of the EGFR/HER2 kinase inhibitor GW572016 on EGFR- and HER2-overexpressing breast cancer cell line proliferation, radiosensitization, and resistance. Int J Radiat Oncol Biol Phys 2004;58:344-52.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 344-352
    • Zhou, H.1    Kim, Y.S.2    Peletier, A.3    McCall, W.4    Earp, H.S.5    Sartor, C.I.6
  • 37
    • 33845883544 scopus 로고    scopus 로고
    • Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-κB (NF-κB) signaling pathway leading to suppression of NF-κB-regulated antiapoptotic and metastatic gene products
    • Ahn KS, Sethi G, Aggarwal BB. Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-κB (NF-κB) signaling pathway leading to suppression of NF-κB-regulated antiapoptotic and metastatic gene products. Mol Pharmacol 2007;71:209-19.
    • (2007) Mol Pharmacol , vol.71 , pp. 209-219
    • Ahn, K.S.1    Sethi, G.2    Aggarwal, B.B.3
  • 38
    • 2342448582 scopus 로고    scopus 로고
    • Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screeningof a traditional herbal medicine three-dimensional structure database
    • Nikolovska-Coleska Z, Xu L, Hu Z, et al. Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screeningof a traditional herbal medicine three-dimensional structure database. J Med Chem 2004;47:2430-40.
    • (2004) J Med Chem , vol.47 , pp. 2430-2440
    • Nikolovska-Coleska, Z.1    Xu, L.2    Hu, Z.3
  • 39
    • 0034469922 scopus 로고    scopus 로고
    • Molecular biology of breast cancer metastasis. Inflammatory breast cancer: Clinical syndrome and molecular determinants
    • Kleer CG, van Golen KL, Merajver SD. Molecular biology of breast cancer metastasis. Inflammatory breast cancer: clinical syndrome and molecular determinants. Breast Cancer Res 2000;2:423-9.
    • (2000) Breast Cancer Res , vol.2 , pp. 423-429
    • Kleer, C.G.1    van Golen, K.L.2    Merajver, S.D.3
  • 41
    • 4444372733 scopus 로고    scopus 로고
    • Pilot study of the mechanism of action of preoperative trastuzumab in patients with primary operable breast tumors overexpressing HER2
    • Gennari R, Menard S, Fagnoni F, et al. Pilot study of the mechanism of action of preoperative trastuzumab in patients with primary operable breast tumors overexpressing HER2. Clin Cancer Res 2004;10:5650-5.
    • (2004) Clin Cancer Res , vol.10 , pp. 5650-5655
    • Gennari, R.1    Menard, S.2    Fagnoni, F.3
  • 42
    • 0037099532 scopus 로고    scopus 로고
    • Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt is required for antibody-mediated effects on p27, cyclin D1, and antitumor action
    • Yakes FM, Chinratanalab W, Ritter CA, King W, Seelig S, Arteaga CL. Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt is required for antibody-mediated effects on p27, cyclin D1, and antitumor action. Cancer Res 2002;62:4132-41.
    • (2002) Cancer Res , vol.62 , pp. 4132-4141
    • Yakes, F.M.1    Chinratanalab, W.2    Ritter, C.A.3    King, W.4    Seelig, S.5    Arteaga, C.L.6
  • 43
    • 33747226732 scopus 로고    scopus 로고
    • Devi GR. siRNA-based approaches in cancer therapy. Cancer Gene Ther 2006;13:819-29.
    • Devi GR. siRNA-based approaches in cancer therapy. Cancer Gene Ther 2006;13:819-29.
  • 44
    • 7944229824 scopus 로고    scopus 로고
    • Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics
    • McManus DC, Lefebvre CA, Cherton-Horvat G, et al. Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics. Oncogene 2004;23:8105-17.
    • (2004) Oncogene , vol.23 , pp. 8105-8117
    • McManus, D.C.1    Lefebvre, C.A.2    Cherton-Horvat, G.3
  • 45
    • 0035020260 scopus 로고    scopus 로고
    • X-linked inhibitor of apoptosis protein activates the phosphatidylinositol 3-kinase/Akt pathway in rat granulosa cells duringfollicular development
    • Asselin E, Wang Y, Tsang BK. X-linked inhibitor of apoptosis protein activates the phosphatidylinositol 3-kinase/Akt pathway in rat granulosa cells duringfollicular development. Endocrinology 2001;142:2451-7.
    • (2001) Endocrinology , vol.142 , pp. 2451-2457
    • Asselin, E.1    Wang, Y.2    Tsang, B.K.3
  • 46
    • 0035476255 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducingl igand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria
    • Zhang XD, Zhang XY, Gray CP, Nguyen T, Hersey P. Tumor necrosis factor-related apoptosis-inducingl igand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria. Cancer Res 2001;61:7339-48.
    • (2001) Cancer Res , vol.61 , pp. 7339-7348
    • Zhang, X.D.1    Zhang, X.Y.2    Gray, C.P.3    Nguyen, T.4    Hersey, P.5
  • 47
    • 0034710543 scopus 로고    scopus 로고
    • Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death
    • Holcik M, Yeh C, Korneluk RG, Chow T. Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death. Oncogene 2000;19:4174-7.
    • (2000) Oncogene , vol.19 , pp. 4174-4177
    • Holcik, M.1    Yeh, C.2    Korneluk, R.G.3    Chow, T.4
  • 48
    • 33645318709 scopus 로고    scopus 로고
    • Survivin expression in breast cancer predicts clinical outcome and is associated with HER2, VEGF, urokinase plasminogen activator and PAI-1
    • Ryan BM, Konecny GE, Kahlert S, et al. Survivin expression in breast cancer predicts clinical outcome and is associated with HER2, VEGF, urokinase plasminogen activator and PAI-1. Ann Oncol 2006;17:597-604.
    • (2006) Ann Oncol , vol.17 , pp. 597-604
    • Ryan, B.M.1    Konecny, G.E.2    Kahlert, S.3
  • 49
    • 1242317030 scopus 로고    scopus 로고
    • Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP)
    • Dan HC, Sun M, Kaneko S, et al. Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP). J Biol Chem 2004;279:5405-12.
    • (2004) J Biol Chem , vol.279 , pp. 5405-5412
    • Dan, H.C.1    Sun, M.2    Kaneko, S.3
  • 50
    • 4544261227 scopus 로고    scopus 로고
    • An IAP-IAP complex inhibits apoptosis
    • Dohi T, Okada K, Xia F, et al. An IAP-IAP complex inhibits apoptosis. J Biol Chem 2004;279:34087-90.
    • (2004) J Biol Chem , vol.279 , pp. 34087-34090
    • Dohi, T.1    Okada, K.2    Xia, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.