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Volumn 19, Issue 9, 2013, Pages 1226-1237

Crystal structure of 3WJ core revealing divalent ion-promoted thermostability and assembly of the Phi29 hexameric motor pRNA

Author keywords

Metal ions; RNA crystal; RNA nanotechnology; RNA therapeutics; Three way junction

Indexed keywords

CONNECTOR PROTEIN; MAGNESIUM ION; MOLECULAR MOTOR; PACKAGING RNA; RNA; UNCLASSIFIED DRUG; CAPSID PROTEIN; DIVALENT CATION; MAGNESIUM; VIRUS DNA; VIRUS RNA;

EID: 84883203974     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.037077.112     Document Type: Article
Times cited : (105)

References (96)
  • 1
    • 79959937835 scopus 로고    scopus 로고
    • Pharmacological characterization of chemically synthesized monomeric pRNA nanoparticles for systemic delivery
    • Abdelmawla S, Guo S, Zhang L, Pulukuri S, Patankar P, Conley P, Trebley J, Guo P, Li QX. 2011. Pharmacological characterization of chemically synthesized monomeric pRNA nanoparticles for systemic delivery. Mol Ther 19: 1312-1322.
    • (2011) Mol Ther , vol.19 , pp. 1312-1322
    • Abdelmawla, S.1    Guo, S.2    Zhang, L.3    Pulukuri, S.4    Patankar, P.5    Conley, P.6    Trebley, J.7    Guo, P.8    Li, Q.X.9
  • 6
    • 34247356107 scopus 로고    scopus 로고
    • Alanine scanning and Fe-BABE probing of the bacteriophage φ29 prohead RNA-connector interaction
    • Atz R, Ma S, Gao J, Anderson DL, Grimes S. 2007. Alanine scanning and Fe-BABE probing of the bacteriophage φ29 prohead RNA-connector interaction. J Mol Biol 369: 239-248.
    • (2007) J Mol Biol , vol.369 , pp. 239-248
    • Atz, R.1    Ma, S.2    Gao, J.3    Anderson, D.L.4    Grimes, S.5
  • 7
    • 0025614359 scopus 로고
    • Phylogenetic analysis and secondary structure of the Bacillus subtilis bacteriophage RNA required for DNA packaging
    • Bailey S, Wichitwechkarn J, Johnson D, Reilly B, Anderson D, Bodley JW. 1990. Phylogenetic analysis and secondary structure of the Bacillus subtilis bacteriophage RNA required for DNA packaging. J Biol Chem 265: 22365-22370.
    • (1990) J Biol Chem , vol.265 , pp. 22365-22370
    • Bailey, S.1    Wichitwechkarn, J.2    Johnson, D.3    Reilly, B.4    Anderson, D.5    Bodley, J.W.6
  • 8
    • 0032707136 scopus 로고    scopus 로고
    • Thiophilic metal ion rescue of phosphorothioate interference within the Tetrahymena ribozyme P4-P6 domain
    • Basu S, Strobel SA. 1999. Thiophilic metal ion rescue of phosphorothioate interference within the Tetrahymena ribozyme P4-P6 domain. RNA 5: 1399-1407.
    • (1999) RNA , vol.5 , pp. 1399-1407
    • Basu, S.1    Strobel, S.A.2
  • 10
    • 77749304812 scopus 로고    scopus 로고
    • Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanine
    • Brenner MD, Scanlan MS, Nahas MK, Ha T, Silverman SK. 2010. Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanine. Biochemistry 49: 1596-1605.
    • (2010) Biochemistry , vol.49 , pp. 1596-1605
    • Brenner, M.D.1    Scanlan, M.S.2    Nahas, M.K.3    Ha, T.4    Silverman, S.K.5
  • 12
    • 0016793007 scopus 로고
    • Urea denaturation of chromatin periodic structure
    • Carlson RD, Olins AL, Olins DE. 1975. Urea denaturation of chromatin periodic structure. Biochemistry 14: 3122-3125.
    • (1975) Biochemistry , vol.14 , pp. 3122-3125
    • Carlson, R.D.1    Olins, A.L.2    Olins, D.E.3
  • 13
    • 84883155175 scopus 로고    scopus 로고
    • RNA structure: Roles of Me2+
    • John Wiley & Sons, Ltd., Hoboken, NJ
    • Carter RJ, Holbrook SR. 2002. RNA structure: Roles of Me2+. In Encyclopedia of Life Sciences, pp. 1-7. John Wiley & Sons, Ltd., Hoboken, NJ.
    • (2002) Encyclopedia of Life Sciences , pp. 1-7
    • Carter, R.J.1    Holbrook, S.R.2
  • 14
    • 0030587890 scopus 로고    scopus 로고
    • Metal-binding sites in the major groove of a large ribozyme domain
    • Cate JH, Doudna JA. 1996. Metal-binding sites in the major groove of a large ribozyme domain. Structure 4: 1221-1229.
    • (1996) Structure , vol.4 , pp. 1221-1229
    • Cate, J.H.1    Doudna, J.A.2
  • 16
    • 0030929889 scopus 로고    scopus 로고
    • A magnesium ion core at the heart of a ribozyme domain
    • Cate JH, Hanna RL, Doudna JA. 1997. A magnesium ion core at the heart of a ribozyme domain. Nat Struct Biol 4: 553-558.
    • (1997) Nat Struct Biol , vol.4 , pp. 553-558
    • Cate, J.H.1    Hanna, R.L.2    Doudna, J.A.3
  • 17
    • 0031060313 scopus 로고    scopus 로고
    • Magnesium-induced conformational change of packaging RNA for procapsid recognition and binding during phage φ29 DNA encapsidation
    • Chen C, Guo P. 1997. Magnesium-induced conformational change of packaging RNA for procapsid recognition and binding during phage φ29 DNA encapsidation. J Virol 71: 495-500.
    • (1997) J Virol , vol.71 , pp. 495-500
    • Chen, C.1    Guo, P.2
  • 18
    • 0034625371 scopus 로고    scopus 로고
    • A dimer as a building block in assembling RNA: A hexamer that gears bacterial virus phi29 DNA-translocating machinery
    • Chen C, Sheng S, Shao Z, Guo P. 2000. A dimer as a building block in assembling RNA: A hexamer that gears bacterial virus phi29 DNA-translocating machinery. J Biol Chem 275: 17510-17516.
    • (2000) J Biol Chem , vol.275 , pp. 17510-17516
    • Chen, C.1    Sheng, S.2    Shao, Z.3    Guo, P.4
  • 20
    • 0021891866 scopus 로고
    • Psoralens as photoactive probes of nucleic acid structure and function: Organic chemistry, photochemistry, and biochemistry
    • Cimino GD, Gamper HB, Isaacs ST, Hearst JE. 1985. Psoralens as photoactive probes of nucleic acid structure and function: Organic chemistry, photochemistry, and biochemistry. Ann Rev Biochem 54: 1151-1193.
    • (1985) Ann Rev Biochem , vol.54 , pp. 1151-1193
    • Cimino, G.D.1    Gamper, H.B.2    Isaacs, S.T.3    Hearst, J.E.4
  • 21
    • 0025998488 scopus 로고
    • Role of divalent metal ions in the hammerhead RNA cleavage reaction
    • Dahm SC, Uhlenbeck OC. 1991. Role of divalent metal ions in the hammerhead RNA cleavage reaction. Biochemistry 30: 9464-9469.
    • (1991) Biochemistry , vol.30 , pp. 9464-9469
    • Dahm, S.C.1    Uhlenbeck, O.C.2
  • 24
    • 1242274330 scopus 로고    scopus 로고
    • A guide to ions and RNA structure
    • Draper DE. 2004. A guide to ions and RNA structure. RNA 10: 335-343.
    • (2004) RNA , vol.10 , pp. 335-343
    • Draper, D.E.1
  • 25
  • 26
    • 45449103050 scopus 로고    scopus 로고
    • Modular assembly of chimeric phi29 packaging RNAs that support DNA packaging
    • Fang Y, Shu D, Xiao F, Guo P, Qin PZ. 2008. Modular assembly of chimeric phi29 packaging RNAs that support DNA packaging. Biochem Biophys Res Commun 372: 589-594.
    • (2008) Biochem Biophys Res Commun , vol.372 , pp. 589-594
    • Fang, Y.1    Shu, D.2    Xiao, F.3    Guo, P.4    Qin, P.Z.5
  • 27
    • 0030817119 scopus 로고    scopus 로고
    • Boundary of pRNA functional domains and minimum pRNA sequence requirement for specific connector binding and DNA packaging of phage φ29
    • Garver K, Guo P. 1997. Boundary of pRNA functional domains and minimum pRNA sequence requirement for specific connector binding and DNA packaging of phage φ29. RNA 3: 1068-1079.
    • (1997) RNA , vol.3 , pp. 1068-1079
    • Garver, K.1    Guo, P.2
  • 29
    • 0036301072 scopus 로고    scopus 로고
    • Detailed architecture of a DNA translocating machine: The high-resolution structure of the bacteriophage φ29 connector particle
    • Guasch A, Pous J, Ibarra B, Gomis-Rüth FX, Valpuesta JM, Sousa N, Carrascosa JL, Coll M. 2002. Detailed architecture of a DNA translocating machine: The high-resolution structure of the bacteriophage φ29 connector particle. J Mol Biol 315: 663-676.
    • (2002) J Mol Biol , vol.315 , pp. 663-676
    • Guasch, A.1    Pous, J.2    Ibarra, B.3    Gomis-Rüth, F.X.4    Valpuesta, J.M.5    Sousa, N.6    Carrascosa, J.L.7    Coll, M.8
  • 30
    • 78649985789 scopus 로고    scopus 로고
    • The emerging field of RNA nanotechnology
    • Guo P. 2010. The emerging field of RNA nanotechnology. Nat Nanotechnol 5: 833-842.
    • (2010) Nat Nanotechnol , vol.5 , pp. 833-842
    • Guo, P.1
  • 31
    • 0023225629 scopus 로고
    • A small viral RNA is required for in vitro packaging of bacteriophage φ29 DNA
    • Guo P, Erickson S, Anderson D. 1987. A small viral RNA is required for in vitro packaging of bacteriophage φ29 DNA. Science 236: 690-694.
    • (1987) Science , vol.236 , pp. 690-694
    • Guo, P.1    Erickson, S.2    Anderson, D.3
  • 32
    • 0032110708 scopus 로고    scopus 로고
    • Inter-RNA interaction of phage φ29 pRNA to form a hexameric complex for viral DNA transportation
    • Guo P, Zhang C, Chen C, Trottier M, Garver K. 1998. Inter-RNA interaction of phage φ29 pRNA to form a hexameric complex for viral DNA transportation. Mol Cell 2: 149-155.
    • (1998) Mol Cell , vol.2 , pp. 149-155
    • Guo, P.1    Zhang, C.2    Chen, C.3    Trottier, M.4    Garver, K.5
  • 33
    • 24944512987 scopus 로고    scopus 로고
    • Specific delivery of therapeutic RNAs to cancer cells via the dimerization mechanism of phi29 motor pRNA
    • Guo S, Tschammer N, Mohammed S, Guo P. 2005a. Specific delivery of therapeutic RNAs to cancer cells via the dimerization mechanism of phi29 motor pRNA. Hum Gene Ther 16: 1097-1109.
    • (2005) Hum Gene Ther , vol.16 , pp. 1097-1109
    • Guo, S.1    Tschammer, N.2    Mohammed, S.3    Guo, P.4
  • 34
    • 24744464829 scopus 로고    scopus 로고
    • Construction of connector arrays with tetragonal to decagonal transition induced by pRNA of phi29 DNApackaging motor
    • Guo Y, Blocker F, Guo P. 2005b. Construction of connector arrays with tetragonal to decagonal transition induced by pRNA of phi29 DNApackaging motor. J Nanosci Nanotechnol 5: 856-863.
    • (2005) J Nanosci Nanotechnol , vol.5 , pp. 856-863
    • Guo, Y.1    Blocker, F.2    Guo, P.3
  • 35
    • 33646356236 scopus 로고    scopus 로고
    • Construction of folate-conjugated pRNA of bacteriophage phi29 DNA packaging motor for delivery of chimeric siRNA to nasopharyngeal carcinoma cells
    • Guo S, Huang F, Guo P. 2006. Construction of folate-conjugated pRNA of bacteriophage phi29 DNA packaging motor for delivery of chimeric siRNA to nasopharyngeal carcinoma cells. Gene Ther 13: 814-820.
    • (2006) Gene Ther , vol.13 , pp. 814-820
    • Guo, S.1    Huang, F.2    Guo, P.3
  • 36
    • 84865436732 scopus 로고    scopus 로고
    • Uniqueness, advantages, challenges, solutions, and perspectives in therapeutics applying RNA nanotechnology
    • Guo P, Haque F, Hallahan B, Reif R, Li H. 2012a. Uniqueness, advantages, challenges, solutions, and perspectives in therapeutics applying RNA nanotechnology. Nucleic Acid Ther 22: 226-245.
    • (2012) Nucleic Acid Ther , vol.22 , pp. 226-245
    • Guo, P.1    Haque, F.2    Hallahan, B.3    Reif, R.4    Li, H.5
  • 37
    • 84868559037 scopus 로고    scopus 로고
    • Synthesis, conjugation, and labeling of multifunctional pRNA nanoparticles for specific delivery of siRNA, drugs and other therapeutics to target cells
    • Guo P, Shu Y, Binzel D, Cinier M. 2012b. Synthesis, conjugation, and labeling of multifunctional pRNA nanoparticles for specific delivery of siRNA, drugs and other therapeutics to target cells. Methods Mol Biol 928: 197-219.
    • (2012) Methods Mol Biol , vol.928 , pp. 197-219
    • Guo, P.1    Shu, Y.2    Binzel, D.3    Cinier, M.4
  • 40
    • 77954821676 scopus 로고    scopus 로고
    • Nuclear magnetic resonance structure of the prohead RNA E-loop hairpin
    • Harris S, Schroeder SJ. 2010. Nuclear magnetic resonance structure of the prohead RNA E-loop hairpin. Biochemistry 49: 5989-5997.
    • (2010) Biochemistry , vol.49 , pp. 5989-5997
    • Harris, S.1    Schroeder, S.J.2
  • 41
    • 0037036444 scopus 로고    scopus 로고
    • Computer modeling of three-dimensional structure of DNA-packaging RNA (pRNA) monomer, dimer, and hexamer of phi29 DNA Packaging motor
    • Hoeprich S, Guo P. 2002. Computer modeling of three-dimensional structure of DNA-packaging RNA (pRNA) monomer, dimer, and hexamer of phi29 DNA Packaging motor. J Biol Chem 277: 20794-20803.
    • (2002) J Biol Chem , vol.277 , pp. 20794-20803
    • Hoeprich, S.1    Guo, P.2
  • 42
    • 0042172858 scopus 로고    scopus 로고
    • Bacterial virus phi29 pRNA as a hammerhead ribozyme escort to destroy hepatitis B virus
    • Hoeprich S, Zhou Q, Guo S, Qi G, Wang Y, Guo P. 2003. Bacterial virus phi29 pRNA as a hammerhead ribozyme escort to destroy hepatitis B virus. Gene Ther 10: 1258-1267.
    • (2003) Gene Ther , vol.10 , pp. 1258-1267
    • Hoeprich, S.1    Zhou, Q.2    Guo, S.3    Qi, G.4    Wang, Y.5    Guo, P.6
  • 43
    • 0022927155 scopus 로고
    • Computer graphic display method for visualizing three-dimensional biological structures
    • Jimenez J, Santisteban A, Carazo JM, Carrascosa JL. 1986. Computer graphic display method for visualizing three-dimensional biological structures. Science 232: 1113-1115.
    • (1986) Science , vol.232 , pp. 1113-1115
    • Jimenez, J.1    Santisteban, A.2    Carazo, J.M.3    Carrascosa, J.L.4
  • 44
    • 79959455998 scopus 로고    scopus 로고
    • Metal ions: Supporting actors in the playbook of small ribozymes
    • Johnson-Buck AE, McDowell SE, Walter NG. 2011. Metal ions: Supporting actors in the playbook of small ribozymes. Met Ions Life Sci 9: 175-196.
    • (2011) Met Ions Life Sci , vol.9 , pp. 175-196
    • Johnson-Buck, A.E.1    McDowell, S.E.2    Walter, N.G.3
  • 46
    • 58249114463 scopus 로고    scopus 로고
    • Mapping metal-binding sites in the catalytic domain of bacterial RNase P RNA
    • Kazantsev AV, Krivenko AA, Pace NR. 2009. Mapping metal-binding sites in the catalytic domain of bacterial RNase P RNA. RNA 15: 266-276.
    • (2009) RNA , vol.15 , pp. 266-276
    • Kazantsev, A.V.1    Krivenko, A.A.2    Pace, N.R.3
  • 47
    • 24944565527 scopus 로고    scopus 로고
    • Controllable self-assembly of nanoparticles for specific delivery of multiple therapeutic molecules to cancer cells using RNA nanotechnology
    • Khaled A, Guo S, Li F, Guo P. 2005. Controllable self-assembly of nanoparticles for specific delivery of multiple therapeutic molecules to cancer cells using RNA nanotechnology. Nano Lett 5: 1797-1808.
    • (2005) Nano Lett , vol.5 , pp. 1797-1808
    • Khaled, A.1    Guo, S.2    Li, F.3    Guo, P.4
  • 48
    • 39449083817 scopus 로고    scopus 로고
    • Analysis of intermolecular base pair formation of prohead RNA of the phage φ29 DNA packaging motor using NMR spectroscopy
    • Kitamura A, Jardine PJ, Anderson DL, Grimes S, Matsuo H. 2008. Analysis of intermolecular base pair formation of prohead RNA of the phage φ29 DNA packaging motor using NMR spectroscopy. Nucleic Acids Res 36: 839-848.
    • (2008) Nucleic Acids Res , vol.36 , pp. 839-848
    • Kitamura, A.1    Jardine, P.J.2    Anderson, D.L.3    Grimes, S.4    Matsuo, H.5
  • 49
    • 34247848007 scopus 로고    scopus 로고
    • Mg2+-dependent folding of a Diels-Alderase ribozyme probed by single-molecule FRET analysis
    • Kobitski AY, Nierth A, Helm M, Jaschke A, Nienhaus GU. 2007. Mg2+-dependent folding of a Diels-Alderase ribozyme probed by single-molecule FRET analysis. Nucleic Acids Res 35: 2047-2059.
    • (2007) Nucleic Acids Res , vol.35 , pp. 2047-2059
    • Kobitski, A.Y.1    Nierth, A.2    Helm, M.3    Jaschke, A.4    Nienhaus, G.U.5
  • 50
    • 13444279054 scopus 로고    scopus 로고
    • The role of phosphate groups in the VS ribozyme-substrate interaction
    • Kovacheva YS, Tzokov SB, Murray IA, Grasby JA. 2004. The role of phosphate groups in the VS ribozyme-substrate interaction. Nucleic Acids Res 32: 6240-6250.
    • (2004) Nucleic Acids Res , vol.32 , pp. 6240-6250
    • Kovacheva, Y.S.1    Tzokov, S.B.2    Murray, I.A.3    Grasby, J.A.4
  • 51
    • 84862969708 scopus 로고    scopus 로고
    • Predicting coaxial helical stacking in RNA junctions
    • Laing C, Wen D, Wang JT, Schlick T. 2012. Predicting coaxial helical stacking in RNA junctions. Nucleic Acids Res 40: 487-498.
    • (2012) Nucleic Acids Res , vol.40 , pp. 487-498
    • Laing, C.1    Wen, D.2    Wang, J.T.3    Schlick, T.4
  • 52
    • 31344436408 scopus 로고    scopus 로고
    • Interaction of gp16 with pRNA and DNA for genome packaging by the motor of bacterial virus phi29
    • Lee TJ, Guo P. 2006. Interaction of gp16 with pRNA and DNA for genome packaging by the motor of bacterial virus phi29. J Mol Biol 356: 589-599.
    • (2006) J Mol Biol , vol.356 , pp. 589-599
    • Lee, T.J.1    Guo, P.2
  • 54
    • 59749090938 scopus 로고    scopus 로고
    • AFM for analysis of structure and dynamics of DNA and protein-DNA complexes
    • Lyubchenko YL, Shlyakhtenko LS. 2009. AFM for analysis of structure and dynamics of DNA and protein-DNA complexes. Methods 47: 206-213.
    • (2009) Methods , vol.47 , pp. 206-213
    • Lyubchenko, Y.L.1    Shlyakhtenko, L.S.2
  • 55
    • 0035980116 scopus 로고    scopus 로고
    • Threedimensional interaction of Phi29 pRNA dimer probed by chemical modification interference, cryo-AFM, and cross-linking
    • Mat-Arip Y, Garver K, Chen C, Sheng S, Shao Z, Guo P. 2001. Threedimensional interaction of Phi29 pRNA dimer probed by chemical modification interference, cryo-AFM, and cross-linking. J Biol Chem 276: 32575-32584.
    • (2001) J Biol Chem , vol.276 , pp. 32575-32584
    • Mat-Arip, Y.1    Garver, K.2    Chen, C.3    Sheng, S.4    Shao, Z.5    Guo, P.6
  • 57
    • 78649677325 scopus 로고    scopus 로고
    • Long-range tertiary interactions in single hammerhead ribozymes bias motional sampling toward catalytically active conformations
    • McDowell SE, Jun JM, Walter NG. 2010. Long-range tertiary interactions in single hammerhead ribozymes bias motional sampling toward catalytically active conformations. RNA 16: 2414-2426.
    • (2010) RNA , vol.16 , pp. 2414-2426
    • McDowell, S.E.1    Jun, J.M.2    Walter, N.G.3
  • 58
    • 0033591710 scopus 로고    scopus 로고
    • Photoinduced crosslinking of RNA by cis-Rh(phen)2Cl2 + and cis-Rh(phen)(phi)Cl2 +: A new family of light activatable nucleic acid cross-linking agents
    • Mohammad T, Chen C, Guo P, Morrison H. 1999. Photoinduced crosslinking of RNA by cis-Rh(phen)2Cl2 + and cis-Rh(phen)(phi)Cl2 +: A new family of light activatable nucleic acid cross-linking agents. Bioorg Med Chem Lett 9: 1703-1708.
    • (1999) Bioorg Med Chem Lett , vol.9 , pp. 1703-1708
    • Mohammad, T.1    Chen, C.2    Guo, P.3    Morrison, H.4
  • 60
    • 0031059866 scopus 로고    scopus 로고
    • Processing of X-ray diffraction data collected in oscillation mode
    • Otwinowski Z, MinorW. 1997. Processing of X-ray diffraction data collected in oscillation mode. Macromolecular Crystallography, Pt A 276: 307-326.
    • (1997) Macromolecular Crystallography, Pt A , vol.276 , pp. 307-326
    • Otwinowski, Z.1    Minor, W.2
  • 61
    • 0029814699 scopus 로고    scopus 로고
    • Rapid preparation of single stranded DNA from PCR products by streptavidin induced electrophoretic mobility shift
    • Pagratis NC. 1996. Rapid preparation of single stranded DNA from PCR products by streptavidin induced electrophoretic mobility shift. Nucleic Acids Res 24: 3645-3646.
    • (1996) Nucleic Acids Res , vol.24 , pp. 3645-3646
    • Pagratis, N.C.1
  • 62
    • 0030876444 scopus 로고    scopus 로고
    • Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation
    • Peracchi A, Beigelman L, Scott EC, Uhlenbeck OC, Herschlag D. 1997. Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation. J Biol Chem 272: 26822-26826.
    • (1997) J Biol Chem , vol.272 , pp. 26822-26826
    • Peracchi, A.1    Beigelman, L.2    Scott, E.C.3    Uhlenbeck, O.C.4    Herschlag, D.5
  • 63
    • 78751562445 scopus 로고    scopus 로고
    • Bidentate RNAmagnesium clamps: On the origin of the special role of magnesium in RNA folding
    • Petrov AS, Bowman JC, Harvey SC, Williams LD. 2011. Bidentate RNAmagnesium clamps: On the origin of the special role of magnesium in RNA folding. RNA 17: 291-297.
    • (2011) RNA , vol.17 , pp. 291-297
    • Petrov, A.S.1    Bowman, J.C.2    Harvey, S.C.3    Williams, L.D.4
  • 64
    • 44349144363 scopus 로고    scopus 로고
    • Singlemolecule nonequilibrium periodic Mg2+-concentration jump experiments reveal details of the early folding pathways of a large RNA
    • Qu X, Smith GJ, Lee KT, Sosnick TR, Pan T, Scherer NF. 2008. Singlemolecule nonequilibrium periodic Mg2+-concentration jump experiments reveal details of the early folding pathways of a large RNA. Proc Natl Acad Sci 105: 6602-6607.
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 6602-6607
    • Qu, X.1    Smith, G.J.2    Lee, K.T.3    Sosnick, T.R.4    Pan, T.5    Scherer, N.F.6
  • 65
    • 0027992332 scopus 로고
    • Characterization of the prohead- pRNA interaction of bacteriophage φ29
    • Reid RJD, Bodley JW, Anderson D. 1994a. Characterization of the prohead- pRNA interaction of bacteriophage φ29. J Biol Chem 269: 5157-5162.
    • (1994) J Biol Chem , vol.269 , pp. 5157-5162
    • Reid, R.J.D.1    Bodley, J.W.2    Anderson, D.3
  • 66
    • 0028175938 scopus 로고
    • Identification of bacteriophage φ29 prohead RNA domains necessary for in vitro DNA-gp3 packaging
    • Reid RJD, Bodley JW, Anderson D. 1994b. Identification of bacteriophage φ29 prohead RNA domains necessary for in vitro DNA-gp3 packaging. J Biol Chem 269: 9084-9089.
    • (1994) J Biol Chem , vol.269 , pp. 9084-9089
    • Reid, R.J.D.1    Bodley, J.W.2    Anderson, D.3
  • 67
    • 0028358819 scopus 로고
    • Probing the structure of bacteriophage φ29 prohead RNA with specific mutations
    • Reid RJD, Zhang F, Benson S, Anderson D. 1994c. Probing the structure of bacteriophage φ29 prohead RNA with specific mutations. J Biol Chem 269: 18656-18661.
    • (1994) J Biol Chem , vol.269 , pp. 18656-18661
    • Reid, R.J.D.1    Zhang, F.2    Benson, S.3    Anderson, D.4
  • 69
    • 45749105933 scopus 로고    scopus 로고
    • A general method for phasing novel complex RNA crystal structures without heavy-atom derivatives
    • Robertson MP, Scott WG. 2008. A general method for phasing novel complex RNA crystal structures without heavy-atom derivatives. Acta Crystallogr D Biol Crystallogr D64: 738-744.
    • (2008) Acta Crystallogr D Biol Crystallogr , vol.D64 , pp. 738-744
    • Robertson, M.P.1    Scott, W.G.2
  • 70
    • 77957127425 scopus 로고    scopus 로고
    • Solving novel RNA structures using only secondary structural fragments
    • Robertson MP, Chi YI, Scott WG. 2010. Solving novel RNA structures using only secondary structural fragments. Methods 52: 168-172.
    • (2010) Methods , vol.52 , pp. 168-172
    • Robertson, M.P.1    Chi, Y.I.2    Scott, W.G.3
  • 72
    • 33846551354 scopus 로고    scopus 로고
    • Counting of six pRNAs of phi29 DNA-packaging motor with customized single molecule dual-view system
    • Shu D, Zhang H, Jin J, Guo P. 2007. Counting of six pRNAs of phi29 DNA-packaging motor with customized single molecule dual-view system. EMBO J 26: 527-537.
    • (2007) EMBO J , vol.26 , pp. 527-537
    • Shu, D.1    Zhang, H.2    Jin, J.3    Guo, P.4
  • 73
    • 78649547538 scopus 로고    scopus 로고
    • Dual-channel singlemolecule fluorescence resonance energy transfer to establish distance parameters for RNA nanoparticles
    • Shu D, Zhang H, Petrenko R, Meller J, Guo P. 2010. Dual-channel singlemolecule fluorescence resonance energy transfer to establish distance parameters for RNA nanoparticles. ACS Nano 4: 6843-6853.
    • (2010) ACS Nano , vol.4 , pp. 6843-6853
    • Shu, D.1    Zhang, H.2    Petrenko, R.3    Meller, J.4    Guo, P.5
  • 74
    • 80455154991 scopus 로고    scopus 로고
    • Thermodynamically stable RNA three-way junctions for constructing multifuntional nanoparticles for delivery of therapeutics
    • Shu D, Shu Y, Haque F, Abdelmawla S, Guo P. 2011a. Thermodynamically stable RNA three-way junctions for constructing multifuntional nanoparticles for delivery of therapeutics. Nat Nanotechnol 6: 658-667.
    • (2011) Nat Nanotechnol , vol.6 , pp. 658-667
    • Shu, D.1    Shu, Y.2    Haque, F.3    Abdelmawla, S.4    Guo, P.5
  • 75
    • 79960023588 scopus 로고    scopus 로고
    • Assembly of therapeutic pRNA-siRNA nanoparticles using bipartite approach
    • Shu Y, Cinier M, Fox SR, Ben-Johnathan N, Guo P. 2011b. Assembly of therapeutic pRNA-siRNA nanoparticles using bipartite approach. Mol Ther 19: 1304-1311.
    • (2011) Mol Ther , vol.19 , pp. 1304-1311
    • Shu, Y.1    Cinier, M.2    Fox, S.R.3    Ben-Johnathan, N.4    Guo, P.5
  • 76
    • 79953171803 scopus 로고    scopus 로고
    • Assembly of multifunctional phi29 pRNA nanoparticles for specific delivery of siRNA and other therapeutics to targeted cells
    • Shu Y, Cinier M, Shu D, Guo P. 2011c. Assembly of multifunctional phi29 pRNA nanoparticles for specific delivery of siRNA and other therapeutics to targeted cells. Methods 54: 204-214.
    • (2011) Methods , vol.54 , pp. 204-214
    • Shu, Y.1    Cinier, M.2    Shu, D.3    Guo, P.4
  • 77
    • 84883203978 scopus 로고    scopus 로고
    • Fabrication of pRNA nanoparticles to deliver therapeutic RNAs and bioactive compounds into tumor cells
    • (in press)
    • Shu Y, Shu D, Haque F, Guo P. 2013a. Fabrication of pRNA nanoparticles to deliver therapeutic RNAs and bioactive compounds into tumor cells. Nat Protoc (in press).
    • (2013) Nat Protoc
    • Shu, Y.1    Shu, D.2    Haque, F.3    Guo, P.4
  • 78
    • 84878025754 scopus 로고    scopus 로고
    • Fabrication of 14 different RNA nanoparticles for specific tumor targeting without accumulation in normal organs
    • Shu Y, Haque F, Shu D, Li W, Zhu Z, Kotb M, Lyubchenko Y, Guo P. 2013b. Fabrication of 14 different RNA nanoparticles for specific tumor targeting without accumulation in normal organs. RNA 19: 767-777.
    • (2013) RNA , vol.19 , pp. 767-777
    • Shu, Y.1    Haque, F.2    Shu, D.3    Li, W.4    Zhu, Z.5    Kotb, M.6    Lyubchenko, Y.7    Guo, P.8
  • 82
    • 0029655643 scopus 로고    scopus 로고
    • Complete inhibition of virion assembly in vivo with mutant pRNA essential for phage φ29 DNA packaging
    • Trottier M, Zhang CL, Guo P. 1996. Complete inhibition of virion assembly in vivo with mutant pRNA essential for phage φ29 DNA packaging. J Virol 70: 55-61.
    • (1996) J Virol , vol.70 , pp. 55-61
    • Trottier, M.1    Zhang, C.L.2    Guo, P.3
  • 83
    • 0033834945 scopus 로고    scopus 로고
    • Probing the structure of monomers and dimers of the bacterial virus phi29 hexamer RNA complex by chemical modification
    • Trottier M, Mat-Arip Y, Zhang C, Chen C, Sheng S, Shao Z, Guo P. 2000. Probing the structure of monomers and dimers of the bacterial virus phi29 hexamer RNA complex by chemical modification. RNA 6: 1257-1266.
    • (2000) RNA , vol.6 , pp. 1257-1266
    • Trottier, M.1    Mat-Arip, Y.2    Zhang, C.3    Chen, C.4    Sheng, S.5    Shao, Z.6    Guo, P.7
  • 84
    • 0026783010 scopus 로고
    • A new interaction between the mouse 5' external transcribed spacer of pre-rRNA and U3 snRNA detected by psoralen crosslinking
    • Tyc K, Steitz JA. 1992. A new interaction between the mouse 5' external transcribed spacer of pre-rRNA and U3 snRNA detected by psoralen crosslinking. Nucleic Acids Res 20: 5375-5382.
    • (1992) Nucleic Acids Res , vol.20 , pp. 5375-5382
    • Tyc, K.1    Steitz, J.A.2
  • 85
    • 30944458838 scopus 로고    scopus 로고
    • Atomic level architecture of group i introns revealed
    • Vicens Q, Cech TR. 2006. Atomic level architecture of group I introns revealed. Trends Biochem Sci 31: 41-51.
    • (2006) Trends Biochem Sci , vol.31 , pp. 41-51
    • Vicens, Q.1    Cech, T.R.2
  • 86
    • 19444373849 scopus 로고    scopus 로고
    • Binding of pRNA to the N-terminal 14 amino acids of connector protein of bacterial phage phi29
    • Xiao F, Moll D, Guo S, Guo P. 2005. Binding of pRNA to the N-terminal 14 amino acids of connector protein of bacterial phage phi29. Nucleic Acids Res 33: 2640-2649.
    • (2005) Nucleic Acids Res , vol.33 , pp. 2640-2649
    • Xiao, F.1    Moll, D.2    Guo, S.3    Guo, P.4
  • 87
    • 56649091437 scopus 로고    scopus 로고
    • Novel mechanism of hexamer ring assembly in protein/RNA interactions revealed by single molecule imaging
    • Xiao F, Zhang H, Guo P. 2008. Novel mechanism of hexamer ring assembly in protein/RNA interactions revealed by single molecule imaging. Nucleic Acids Res 36: 6620-6632.
    • (2008) Nucleic Acids Res , vol.36 , pp. 6620-6632
    • Xiao, F.1    Zhang, H.2    Guo, P.3
  • 88
    • 0028361637 scopus 로고
    • The proximate 5' and 3' ends of the 120-base viral RNA (pRNA) are crucial for the packaging of bacteriophage φ29 DNA
    • Zhang CL, Lee C-S, Guo P. 1994. The proximate 5' and 3' ends of the 120-base viral RNA (pRNA) are crucial for the packaging of bacteriophage φ29 DNA. Virology 201: 77-85.
    • (1994) Virology , vol.201 , pp. 77-85
    • Zhang, C.L.1    Lee, C.-S.2    Guo, P.3
  • 89
    • 0028978266 scopus 로고
    • Inhibition of phage φ29 assembly by antisense oligonucleotides targeting viral pRNA essential for DNA packaging
    • Zhang CL, Garver K, Guo P. 1995a. Inhibition of phage φ29 assembly by antisense oligonucleotides targeting viral pRNA essential for DNA packaging. Virology 211: 568-576.
    • (1995) Virology , vol.211 , pp. 568-576
    • Zhang, C.L.1    Garver, K.2    Guo, P.3
  • 90
    • 0029437961 scopus 로고
    • Confirmation of the helical structure of the 5'/3' termini of the essential DNA packaging pRNA of phage φ29
    • Zhang CL, Tellinghuisen T, Guo P. 1995b. Confirmation of the helical structure of the 5'/3' termini of the essential DNA packaging pRNA of phage φ29. RNA 1: 1041-1050.
    • (1995) RNA , vol.1 , pp. 1041-1050
    • Zhang, C.L.1    Tellinghuisen, T.2    Guo, P.3
  • 91
    • 0028966682 scopus 로고
    • Circularly permuted viral pRNA active and specific in the packaging of bacteriophage φ29 DNA
    • Zhang CL, Trottier M, Guo PX. 1995c. Circularly permuted viral pRNA active and specific in the packaging of bacteriophage φ29 DNA. Virology 207: 442-451.
    • (1995) Virology , vol.207 , pp. 442-451
    • Zhang, C.L.1    Trottier, M.2    Guo, P.X.3
  • 92
    • 0030893424 scopus 로고    scopus 로고
    • Use of circular permutation to assess six bulges and four loops of DNA-Packaging pRNA of bacteriophage φ29
    • Zhang CL, Tellinghuisen T, Guo P. 1997. Use of circular permutation to assess six bulges and four loops of DNA-Packaging pRNA of bacteriophage φ29. RNA 3: 315-322.
    • (1997) RNA , vol.3 , pp. 315-322
    • Zhang, C.L.1    Tellinghuisen, T.2    Guo, P.3
  • 94
    • 0035866620 scopus 로고    scopus 로고
    • Chemical modification patterns of active and inactive as well as procapsid-bound and unbound DNA-packagingRNAof bacterial virus Phi29
    • Zhang C, Trottier M, Chen C, Guo P. 2001. Chemical modification patterns of active and inactive as well as procapsid-bound and unbound DNA-packagingRNAof bacterial virus Phi29. Virology 281: 281-293.
    • (2001) Virology , vol.281 , pp. 281-293
    • Zhang, C.1    Trottier, M.2    Chen, C.3    Guo, P.4
  • 95
    • 79958716788 scopus 로고    scopus 로고
    • Dual functionalRNAnanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific deliveryandHIV-1inhibition
    • Zhou J, Shu Y, Guo P, Smith D, Rossi J. 2011. Dual functionalRNAnanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific deliveryandHIV-1inhibition. Methods 54: 284-294.
    • (2011) Methods , vol.54 , pp. 284-294
    • Zhou, J.1    Shu, Y.2    Guo, P.3    Smith, D.4    Rossi, J.5


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