Human TLR8 senses UR/URR motifs in bacterial and mitochondrial RNA

EMBO Reports

Volumn 16, Issue 12, 2015, Pages 1656-1663

  Krüger, Anne ^a   Oldenburg, Marina ^a   Chebrolu, Chiranjeevi ^a   Beisser, Daniela ^a   Kolter, Julia ^b   Sigmund, Anna M ^a   Steinmann, Jörg ^a   Schäfer, Simon ^a   Hochrein, Hubertus ^c   Rahmann, Sven ^a   Wagner, Hermann ^d   Henneke, Philipp ^b   Hornung, Veit ^e   Buer, Jan ^a   Kirschning, Carsten J ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c Bavarian Nordic GmbH   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF BONN   (Germany)

Author keywords

bacteria; human TLR8; mitochondrial; ribosomal; RNA

Indexed keywords

BACTERIAL RNA; CHLOROQUINE; MITOCHONDRIAL RNA; MYELOID DIFFERENTIATION FACTOR 88; OLIGORIBONUCLEOTIDE; RNA 16S; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 13; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; UNCLASSIFIED DRUG; URIDINE; RNA; RNA, MITOCHONDRIAL; TLR8 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BACTERIAL INFECTION; BLOOD CULTURE; CELL ACTIVATION; CONTROLLED STUDY; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE-STRANDED RNA VIRUS; STAPHYLOCOCCUS AUREUS; UPREGULATION; ANIMAL; CHEMISTRY; GENETICS; IMMUNOLOGY; MONONUCLEAR CELL; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; ESCHERICHIA COLI; HUMANS; LEUKOCYTES, MONONUCLEAR; MICE; OLIGORIBONUCLEOTIDES; RNA; RNA, BACTERIAL; RNA, RIBOSOMAL, 16S; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTOR 8;

EID: 84954373228     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201540861     Document Type: Article

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