A narrow repertoire of transcriptional modules responsive to pyogenic bacteria is impaired in patients carrying loss-of-function mutations in MYD88 or IRAK4

Nature Immunology

Volumn 15, Issue 12, 2014, Pages 1134-1142

  Alsina, Laia ^a,b   Israelsson, Elisabeth ^c   Altman, Matthew C ^c   Dang, Kristen K ^c   Ghandil, Pegah ^d,e   Israel, Laura ^d,e   Von Bernuth, Horst ^d,e,f   Baldwin, Nicole ^a   Qin, Huanying ^a   Jin, Zongbo ^a   Banchereau, Romain ^a   Anguiano, Esperanza ^a   Ionan, Alexei ^a   Abel, Laurent ^d,e   Puel, Anne ^d,e,g   Picard, Capucine ^d,e,g,h   Pascual, Virginia ^a   Casanova, Jean Laurent ^d,e,g,h,i   Chaussabel, Damien ^a,c,j  

^a BAYLOR INSTITUTE FOR IMMUNOLOGY RESEARCH   (United States)

^b UNIVERSITY OF BARCELONA   (Spain)

^c BENAROYA RESEARCH INSTITUTE   (United States)

^d IMAGINE INSTITUTE   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f HUMBOLDT UNIVERSITY   (Germany)

^g ROCKEFELLER UNIVERSITY   (United States)

^h HÔPITAL NECKER ENFANTS MALADES   (France)

ⁱ HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^j SIDRA MEDICAL AND RESEARCH CENTER   (Qatar)

more..

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TRANSCRIPTOME; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK4 PROTEIN, HUMAN; MYD88 PROTEIN, HUMAN;

ADULT; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC TRANSCRIPTION; HUMAN; HYPOTHESIS; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IN VITRO STUDY; INNATE IMMUNITY; LOSS OF FUNCTION MUTATION; MALE; PRESCHOOL CHILD; PROTEIN FUNCTION; PYOGENIC BACTERIUM; SCHOOL CHILD; ADOLESCENT; CLUSTER ANALYSIS; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; INFANT; MUTATION;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; CLUSTER ANALYSIS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNITY, INNATE; IMMUNOLOGIC DEFICIENCY SYNDROMES; INFANT; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MALE; MUTATION; MYELOID DIFFERENTIATION FACTOR 88; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; TRANSCRIPTOME;

EID: 84911189024     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3028     Document Type: Article

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