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Volumn 64, Issue 1, 2016, Pages 236-244

Purified Betacyanins from Hylocereus undatus Peel Ameliorate Obesity and Insulin Resistance in High-Fat-Diet-Fed Mice

Author keywords

betacyanins; hepatic steatosis; Hylocereus undatus peel; insulin resistance; obesity

Indexed keywords

BIOCHEMISTRY; FATTY ACIDS; FREE RADICALS; GENES; INSULIN; LIQUID CHROMATOGRAPHY; MAMMALS; MASS SPECTROMETRY; METABOLISM; NUTRITION; PURIFICATION;

EID: 84954323719     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.5b05177     Document Type: Article
Times cited : (62)

References (44)
  • 1
    • 33845886915 scopus 로고    scopus 로고
    • Abdominal obesity and metabolic syndrome
    • Despres, J. P.; Lemieux, I. Abdominal obesity and metabolic syndrome Nature 2006, 444, 881-887 10.1038/nature05488
    • (2006) Nature , vol.444 , pp. 881-887
    • Despres, J.P.1    Lemieux, I.2
  • 2
    • 0034611791 scopus 로고    scopus 로고
    • Obesity as a medical problem
    • Kopelman, P. G. Obesity as a medical problem Nature 2000, 404, 635-643 10.1038/35007508
    • (2000) Nature , vol.404 , pp. 635-643
    • Kopelman, P.G.1
  • 3
    • 77956338564 scopus 로고    scopus 로고
    • Possible anti-obesity therapeutics from nature-A review
    • Yun, J. W. Possible anti-obesity therapeutics from nature-A review Phytochemistry 2010, 71, 1625-1641 10.1016/j.phytochem.2010.07.011
    • (2010) Phytochemistry , vol.71 , pp. 1625-1641
    • Yun, J.W.1
  • 6
    • 84884608778 scopus 로고    scopus 로고
    • Characterisation and determination of in vitro antioxidant potential of betalains from Talinum triangulare (Jacq.) Willd
    • Swarna, J.; Lokeswari, T. S.; Smita, M.; Ravindhran, R. Characterisation and determination of in vitro antioxidant potential of betalains from Talinum triangulare (Jacq.) Willd Food Chem. 2013, 141, 4382-4390 10.1016/j.foodchem.2013.06.108
    • (2013) Food Chem. , vol.141 , pp. 4382-4390
    • Swarna, J.1    Lokeswari, T.S.2    Smita, M.3    Ravindhran, R.4
  • 7
    • 84903975651 scopus 로고    scopus 로고
    • Antioxidant capacity of betacyanins as radical scavengers for peroxyl radical and nitric oxide
    • Taira, J.; Tsuchida, E.; Katoh, M. C.; Uehara, M.; Ogi, T. Antioxidant capacity of betacyanins as radical scavengers for peroxyl radical and nitric oxide Food Chem. 2015, 166, 531-536 10.1016/j.foodchem.2014.05.102
    • (2015) Food Chem. , vol.166 , pp. 531-536
    • Taira, J.1    Tsuchida, E.2    Katoh, M.C.3    Uehara, M.4    Ogi, T.5
  • 8
    • 84871338303 scopus 로고    scopus 로고
    • Blood pressure-lowering effects of beetroot juice and novel beetroot-enriched bread products in normotensive male subjects
    • Hobbs, D. A.; Kaffa, N.; George, T. W.; Methven, L.; Lovegrove, J. A. Blood pressure-lowering effects of beetroot juice and novel beetroot-enriched bread products in normotensive male subjects Br. J. Nutr. 2012, 108, 2066-2074 10.1017/S0007114512000190
    • (2012) Br. J. Nutr. , vol.108 , pp. 2066-2074
    • Hobbs, D.A.1    Kaffa, N.2    George, T.W.3    Methven, L.4    Lovegrove, J.A.5
  • 9
    • 80053937226 scopus 로고    scopus 로고
    • Physiological properties of beetroot crisps applied in standard and dyslipidaemic diets of rats
    • Wroblewska, M.; Juskiewicz, J.; Wiczkowski, W. Physiological properties of beetroot crisps applied in standard and dyslipidaemic diets of rats Lipids Health Dis. 2011, 10, 178 10.1186/1476-511X-10-178
    • (2011) Lipids Health Dis. , vol.10 , pp. 178
    • Wroblewska, M.1    Juskiewicz, J.2    Wiczkowski, W.3
  • 10
    • 70450205056 scopus 로고    scopus 로고
    • Betalains: Properties, sources, applications, and stability-A review
    • Azeredo, H. M. C. Betalains: Properties, sources, applications, and stability-A review Int. J. Food Sci. Technol. 2009, 44, 2365-2376 10.1111/j.1365-2621.2007.01668.x
    • (2009) Int. J. Food Sci. Technol. , vol.44 , pp. 2365-2376
    • Azeredo, H.M.C.1
  • 11
    • 33750530838 scopus 로고    scopus 로고
    • Betanin, the main pigment of red beet: Molecular origin of its exceptionally high free radical-scavenging activity
    • Gliszczynska-Swiglo, A.; Szymusiak, H.; Malinowska, P. Betanin, the main pigment of red beet: molecular origin of its exceptionally high free radical-scavenging activity Food Addit. Contam. 2006, 23, 1079-1087 10.1080/02652030600986032
    • (2006) Food Addit. Contam. , vol.23 , pp. 1079-1087
    • Gliszczynska-Swiglo, A.1    Szymusiak, H.2    Malinowska, P.3
  • 12
    • 0037048769 scopus 로고    scopus 로고
    • Fruit flesh betacyanin pigments in Hylocereus cacti
    • Wybraniec, S.; Mizrahi, Y. Fruit flesh betacyanin pigments in Hylocereus cacti J. Agric. Food Chem. 2002, 50, 6086-6089 10.1021/jf020145k
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 6086-6089
    • Wybraniec, S.1    Mizrahi, Y.2
  • 13
    • 84970872356 scopus 로고    scopus 로고
    • Hypocholesterolemic Effect of Fermented Red Pitaya (Hylocereus polyrhizus) Juice in Diet-Induced Hypercholesterolemic Rats
    • Yusof, R. M.; Akhiruddin, M. A. Hypocholesterolemic Effect of Fermented Red Pitaya (Hylocereus polyrhizus) Juice in Diet-Induced Hypercholesterolemic Rats Ann. Nutr. Metab. 2009, 55, 92-92
    • (2009) Ann. Nutr. Metab. , vol.55 , pp. 92
    • Yusof, R.M.1    Akhiruddin, M.A.2
  • 14
    • 84906762112 scopus 로고    scopus 로고
    • Metabolite profiling of red and white pitayas (Hylocereus polyrhizus and Hylocereus undatus) for comparing betalain biosynthesis and antioxidant activity
    • Suh, D. H.; Lee, S.; Heo, D. Y.; Kim, Y. S.; Cho, S. K.; Lee, S.; Lee, C. H. Metabolite profiling of red and white pitayas (Hylocereus polyrhizus and Hylocereus undatus) for comparing betalain biosynthesis and antioxidant activity J. Agric. Food Chem. 2014, 62, 8764-8771 10.1021/jf5020704
    • (2014) J. Agric. Food Chem. , vol.62 , pp. 8764-8771
    • Suh, D.H.1    Lee, S.2    Heo, D.Y.3    Kim, Y.S.4    Cho, S.K.5    Lee, S.6    Lee, C.H.7
  • 15
    • 84904122899 scopus 로고    scopus 로고
    • Optimization of processing parameters for extraction of amylase enzyme from dragon (Hylocereus polyrhizus) peel using response surface methodology
    • Amid, M.; Abdul Manap, M. Y.; Zohdi, N. Optimization of processing parameters for extraction of amylase enzyme from dragon (Hylocereus polyrhizus) peel using response surface methodology Sci. World J. 2014, 2014, 1-12 10.1155/2014/640949
    • (2014) Sci. World J. , vol.2014 , pp. 1-12
    • Amid, M.1    Abdul Manap, M.Y.2    Zohdi, N.3
  • 16
    • 0542423232 scopus 로고    scopus 로고
    • Characterization and quantification of betacyanin pigments from diverse Amaranthus species
    • Cai, Y.; Sun, M.; Wu, H.; Huang, R.; Corke, H. Characterization and quantification of betacyanin pigments from diverse Amaranthus species J. Agric. Food Chem. 1998, 46, 2063-2070 10.1021/jf9709966
    • (1998) J. Agric. Food Chem. , vol.46 , pp. 2063-2070
    • Cai, Y.1    Sun, M.2    Wu, H.3    Huang, R.4    Corke, H.5
  • 18
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch, J.; Lees, M.; Sloane Stanley, G. H. A simple method for the isolation and purification of total lipides from animal tissues J. Biol. Chem. 1957, 226, 497-509
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 20
    • 0036128032 scopus 로고    scopus 로고
    • Betacyanins in fruits from red-purple pitaya, Hylocereus polyrhizus (Weber) Britton & Rose
    • Stintzing, F. C.; Schieber, A.; Carle, R. Betacyanins in fruits from red-purple pitaya, Hylocereus polyrhizus (Weber) Britton & Rose Food Chem. 2002, 77, 101-106 10.1016/S0308-8146(01)00374-0
    • (2002) Food Chem. , vol.77 , pp. 101-106
    • Stintzing, F.C.1    Schieber, A.2    Carle, R.3
  • 21
    • 37549005953 scopus 로고    scopus 로고
    • Chromatographic investigation on acyl migration in betacyanins and their decarboxylated derivatives
    • Wybraniec, S. Chromatographic investigation on acyl migration in betacyanins and their decarboxylated derivatives J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2008, 861, 40-47 10.1016/j.jchromb.2007.11.023
    • (2008) J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. , vol.861 , pp. 40-47
    • Wybraniec, S.1
  • 22
    • 24344479101 scopus 로고    scopus 로고
    • Generation of decarboxylated and dehydrogenated betacyanins in thermally treated purified fruit extract from purple pitaya (Hylocereus polyrhizus) monitored by LC-MS/MS
    • Wybraniec, S.; Mizrahi, Y. Generation of decarboxylated and dehydrogenated betacyanins in thermally treated purified fruit extract from purple pitaya (Hylocereus polyrhizus) monitored by LC-MS/MS J. Agric. Food Chem. 2005, 53, 6704-6712 10.1021/jf050700t
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 6704-6712
    • Wybraniec, S.1    Mizrahi, Y.2
  • 23
    • 77952151217 scopus 로고    scopus 로고
    • Profiles of betacyanins in epidermal layers of grafted and light-stressed cacti studied by LC-DAD-ESI-MS/MS
    • Wybraniec, S.; Stalica, P.; Sporna, A.; Mizrahi, Y. Profiles of betacyanins in epidermal layers of grafted and light-stressed cacti studied by LC-DAD-ESI-MS/MS J. Agric. Food Chem. 2010, 58, 5347-5354 10.1021/jf100065w
    • (2010) J. Agric. Food Chem. , vol.58 , pp. 5347-5354
    • Wybraniec, S.1    Stalica, P.2    Sporna, A.3    Mizrahi, Y.4
  • 24
    • 33748911624 scopus 로고    scopus 로고
    • Rapid identification of betacyanins from Amaranthus tricolor, Gomphrena globosa, and Hylocereus polyrhizus by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight mass spectrometry (MALDI-QIT-TOF MS)
    • Cai, Y. Z.; Xing, J.; Sun, M.; Corke, H. Rapid identification of betacyanins from Amaranthus tricolor, Gomphrena globosa, and Hylocereus polyrhizus by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight mass spectrometry (MALDI-QIT-TOF MS) J. Agric. Food Chem. 2006, 54, 6520-6526 10.1021/jf0609983
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 6520-6526
    • Cai, Y.Z.1    Xing, J.2    Sun, M.3    Corke, H.4
  • 25
    • 84970873616 scopus 로고    scopus 로고
    • Effects of red pitaya fruit (Hylocereus polyrhizus) consumption on blood glucose level and lipid profile in tye 2 diabetic subjects
    • Abd Hadi, N.; Marhazlina, M.; Rohin, Mohd Adzim Khalili; Mohd Yusof, R. Effects of red pitaya fruit (Hylocereus polyrhizus) consumption on blood glucose level and lipid profile in tye 2 diabetic subjects Borneo Sci. 2012, 31, 113-129
    • (2012) Borneo Sci. , vol.31 , pp. 113-129
    • Abd Hadi, N.1    Marhazlina, M.2    Rohin, M.A.K.3    Mohd Yusof, R.4
  • 27
    • 0037356826 scopus 로고    scopus 로고
    • The role of the novel adipocyte-derived hormone adiponectin in human disease
    • Diez, J. J.; Iglesias, P. The role of the novel adipocyte-derived hormone adiponectin in human disease Eur. J. Endocrinol. 2003, 148, 293-300 10.1530/eje.0.1480293
    • (2003) Eur. J. Endocrinol. , vol.148 , pp. 293-300
    • Diez, J.J.1    Iglesias, P.2
  • 28
    • 33646494846 scopus 로고    scopus 로고
    • Secretion of adiponectin by human placenta: Differential modulation of adiponectin and its receptors by cytokines
    • Chen, J.; Tan, B.; Karteris, E.; Zervou, S.; Digby, J.; Hillhouse, E. W.; Vatish, M.; Randeva, H. S. Secretion of adiponectin by human placenta: differential modulation of adiponectin and its receptors by cytokines Diabetologia 2006, 49, 1292-1302 10.1007/s00125-006-0194-7
    • (2006) Diabetologia , vol.49 , pp. 1292-1302
    • Chen, J.1    Tan, B.2    Karteris, E.3    Zervou, S.4    Digby, J.5    Hillhouse, E.W.6    Vatish, M.7    Randeva, H.S.8
  • 30
    • 79960402453 scopus 로고    scopus 로고
    • Mitochondrial carnitine palmitoyltransferase 1a (CPT1a) is part of an outer membrane fatty acid transfer complex
    • Lee, K.; Kerner, J.; Hoppel, C. L. Mitochondrial carnitine palmitoyltransferase 1a (CPT1a) is part of an outer membrane fatty acid transfer complex J. Biol. Chem. 2011, 286, 25655-25662 10.1074/jbc.M111.228692
    • (2011) J. Biol. Chem. , vol.286 , pp. 25655-25662
    • Lee, K.1    Kerner, J.2    Hoppel, C.L.3
  • 31
    • 0028199629 scopus 로고
    • Isolation of the human peroxisomal acyl-CoA oxidase gene: Organization, promoter analysis, and chromosomal localization
    • Varanasi, U.; Chu, R.; Chu, S.; Espinosa, R.; LeBeau, M. M.; Reddy, J. K. Isolation of the human peroxisomal acyl-CoA oxidase gene: Organization, promoter analysis, and chromosomal localization Proc. Natl. Acad. Sci. U. S. A. 1994, 91, 3107-3111 10.1073/pnas.91.8.3107
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 3107-3111
    • Varanasi, U.1    Chu, R.2    Chu, S.3    Espinosa, R.4    LeBeau, M.M.5    Reddy, J.K.6
  • 33
    • 84902659944 scopus 로고    scopus 로고
    • Hepatic PPAR and LXRα independently regulate lipid accumulation in the livers of genetically obese mice
    • Matsusue, K.; Aibara, D.; Hayafuchi, R.; Matsuo, K.; Takiguchi, S.; Gonzalez, F. J.; Yamano, S. Hepatic PPAR and LXRα independently regulate lipid accumulation in the livers of genetically obese mice FEBS Lett. 2014, 588, 2277-2281 10.1016/j.febslet.2014.05.012
    • (2014) FEBS Lett. , vol.588 , pp. 2277-2281
    • Matsusue, K.1    Aibara, D.2    Hayafuchi, R.3    Matsuo, K.4    Takiguchi, S.5    Gonzalez, F.J.6    Yamano, S.7
  • 34
    • 0037162719 scopus 로고    scopus 로고
    • Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
    • Yang, T.; Espenshade, P. J.; Wright, M. E.; Yabe, D.; Gong, Y.; Aebersold, R.; Goldstein, J. L.; Brown, M. S. Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER Cell 2002, 110, 489-500 10.1016/S0092-8674(02)00872-3
    • (2002) Cell , vol.110 , pp. 489-500
    • Yang, T.1    Espenshade, P.J.2    Wright, M.E.3    Yabe, D.4    Gong, Y.5    Aebersold, R.6    Goldstein, J.L.7    Brown, M.S.8
  • 38
    • 68149091653 scopus 로고    scopus 로고
    • Circulating Fibroblast Growth Factor-21 Is Elevated in Impaired Glucose Tolerance and Type 2 Diabetes and Correlates with Muscle and Hepatic Insulin Resistance
    • Chavez, A. O.; Molina-Carrion, M.; Abdul-Ghani, M. A.; Folli, F.; DeFronzo, R. A.; Tripathy, D. Circulating Fibroblast Growth Factor-21 Is Elevated in Impaired Glucose Tolerance and Type 2 Diabetes and Correlates With Muscle and Hepatic Insulin Resistance Diabetes Care 2009, 32, 1542-1546 10.2337/dc09-0684
    • (2009) Diabetes Care , vol.32 , pp. 1542-1546
    • Chavez, A.O.1    Molina-Carrion, M.2    Abdul-Ghani, M.A.3    Folli, F.4    DeFronzo, R.A.5    Tripathy, D.6
  • 40
    • 66749106885 scopus 로고    scopus 로고
    • Serum Fibroblast Growth Factor 21 Is Associated with Adverse Lipid Profiles and -Glutamyltransferase but Not Insulin Sensitivity in Chinese Subjects
    • Li, H. T.; Bao, Y. Q.; Xu, A. M.; Pan, X. P.; Lu, J. X.; Wu, H. Y.; Lu, H. J.; Xiang, K. S.; Jia, W. P. Serum Fibroblast Growth Factor 21 Is Associated with Adverse Lipid Profiles and -Glutamyltransferase But Not Insulin Sensitivity in Chinese Subjects J. Clin. Endocrinol. Metab. 2009, 94, 2151-2156 10.1210/jc.2008-2331
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 2151-2156
    • Li, H.T.1    Bao, Y.Q.2    Xu, A.M.3    Pan, X.P.4    Lu, J.X.5    Wu, H.Y.6    Lu, H.J.7    Xiang, K.S.8    Jia, W.P.9
  • 43
    • 28444440307 scopus 로고    scopus 로고
    • Relative inhibition of lipid peroxidation, cyclooxygenase enzymes, and human tumor cell proliferation by natural food colors
    • Reddy, M. K.; Alexander-Lindo, R. L.; Nair, M. G. Relative inhibition of lipid peroxidation, cyclooxygenase enzymes, and human tumor cell proliferation by natural food colors J. Agric. Food Chem. 2005, 53, 9268-9273 10.1021/jf051399j
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 9268-9273
    • Reddy, M.K.1    Alexander-Lindo, R.L.2    Nair, M.G.3
  • 44
    • 84889249261 scopus 로고    scopus 로고
    • Betanin, a beetroot component, induces nuclear factor erythroid-2-related factor 2-mediated expression of detoxifying/antioxidant enzymes in human liver cell lines
    • Krajka-Kuzniak, V.; Paluszczak, J.; Szaefer, H.; Baer-Dubowska, W. Betanin, a beetroot component, induces nuclear factor erythroid-2-related factor 2-mediated expression of detoxifying/antioxidant enzymes in human liver cell lines Br. J. Nutr. 2013, 110, 2138-2149 10.1017/S0007114513001645
    • (2013) Br. J. Nutr. , vol.110 , pp. 2138-2149
    • Krajka-Kuzniak, V.1    Paluszczak, J.2    Szaefer, H.3    Baer-Dubowska, W.4


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