In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity

Nature Medicine

Volumn 22, Issue 1, 2016, Pages 64-71

  Sagoo, Pervinder ^a,b   Garcia, Zacarias ^a,b   Breart, Beatrice ^a,b   Lemaître, Fabrice ^a,b   Michonneau, David ^a,b   Albert, Matthew L ^a,c   Levy, Yves ^d,e,f,g   Bousso, Philippe ^a,b,d  

^a INSTITUT PASTEUR   (France)

^b INSTITUT PASTEUR   (France)

^c INSERM   (France)

^d Vaccine Research Institute   (France)

^e INSERM U955   (France)

^f FACULTÉ DE MÉDECINE   (France)

^g HENRI MONDOR HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

INFLAMMASOME; MODIFIED VACCINIA VIRUS ANKARA 5T4 VACCINE; APOPTOSIS REGULATORY PROTEIN; PYCARD PROTEIN, MOUSE;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; BURST FORMING UNIT; CELL DEATH; CONTROLLED STUDY; IMMUNE RESPONSE; IN VIVO STUDY; INFLAMMATORY CELL; INNATE IMMUNITY; KINETICS; LYMPH NODE; MACROPHAGE; MOLECULAR IMAGING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; T LYMPHOCYTE; VACCINIA; VIRUS INFECTION; ANIMAL; FLOW CYTOMETRY; IMMUNOLOGY; POXVIRUS INFECTION; VACCINIA VIRUS;

ADAPTIVE IMMUNITY; ANIMALS; APOPTOSIS REGULATORY PROTEINS; FLOW CYTOMETRY; IMMUNITY, INNATE; INFLAMMASOMES; LYMPH NODES; MACROPHAGES; MICE; POXVIRIDAE INFECTIONS; T-LYMPHOCYTES; VACCINIA VIRUS;

EID: 84954298362     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4016     Document Type: Article

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