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Volumn 7, Issue 4, 2015, Pages

Large scale industrialized cell expansion: Producing the critical raw material for biofabrication processes

Author keywords

3D culture; bioreactors; cell expansion; cellular biomanufacturing

Indexed keywords

BIOREACTORS; CELLULAR MANUFACTURING; DISEASE CONTROL;

EID: 84954131753     PISSN: 17585082     EISSN: 17585090     Source Type: Journal    
DOI: 10.1088/1758-5090/7/4/044103     Document Type: Article
Times cited : (53)

References (111)
  • 1
    • 84897507656 scopus 로고    scopus 로고
    • Regenerative medicine: The hurdles and hopes
    • 255-8
    • Baptista P M and Atala A 2015 Regenerative medicine: the hurdles and hopes Transl. Res. 163 255-8
    • (2015) Transl. Res. , vol.163 , pp. 255-258
    • Baptista, P.M.1    Atala, A.2
  • 3
    • 84859812143 scopus 로고    scopus 로고
    • A 3D organoid kidney culture model engineered for high-throughput nephrotoxicity assays
    • 4700-11
    • Astashkina A I, Mann B K, Prestwich G D and Grainger D W 2012 A 3D organoid kidney culture model engineered for high-throughput nephrotoxicity assays Biomaterials 33 4700-11
    • (2012) Biomaterials , vol.33 , pp. 4700-4711
    • Astashkina, A.I.1    Mann, B.K.2    Prestwich, G.D.3    Grainger, D.W.4
  • 4
    • 65649133932 scopus 로고    scopus 로고
    • A micro cell culture analog (microCCA) with 3D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs
    • A micro cell culture analog (microCCA) with 3D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs 1385-94
    • Sung J H and Shuler M L 2009 A micro cell culture analog (microCCA) with 3D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs Lab Chip 9 1385-94
    • (2009) Lab Chip , vol.9 , pp. 1385-1394
    • Sung, J.H.1    Shuler, M.L.2
  • 6
    • 84942897002 scopus 로고    scopus 로고
    • Frankenstein's chips: Scientists turn to build-em-yourself Guinea pigs
    • 24-6
    • Weiss P 2005 Frankenstein's chips: scientists turn to build-em-yourself guinea pigs Sci. News 167 24-6
    • (2005) Sci. News , vol.167 , pp. 24-26
    • Weiss, P.1
  • 7
    • 77957947156 scopus 로고    scopus 로고
    • Multiplexed, high-throughput analysis of 3D microtissue suspensions
    • Integr. Biol. (Camb.) 517-27
    • Chen A A, Underhill G H and Bhatia S N 2010 Multiplexed, high-throughput analysis of 3D microtissue suspensions Integr. Biol. (Camb.) 2 517-27
    • (2010) Integr. Biol. (Camb.) , vol.2 , pp. 517-527
    • Chen, A.A.1    Underhill, G.H.2    Bhatia, S.N.3
  • 8
    • 84907009889 scopus 로고    scopus 로고
    • A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening
    • Exp. Biol. Med. (Maywood) 1240-54
    • Heylman C, Sobrino A, Shirure V S, Hughes C C and George S C 2014 A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening Exp. Biol. Med. (Maywood) 239 1240-54
    • (2014) Exp. Biol. Med. (Maywood) , vol.239 , pp. 1240-1254
    • Heylman, C.1    Sobrino, A.2    Shirure, V.S.3    Hughes, C.C.4    George, S.C.5
  • 9
    • 77449119885 scopus 로고    scopus 로고
    • A microfluidic hepatic coculture platform for cell-based drug metabolism studies
    • 1036-44
    • Novik E, Maguire T J, Chao P, Cheng K C and Yarmush M L 2010 A microfluidic hepatic coculture platform for cell-based drug metabolism studies Biochem. Pharmacol. 79 1036-44
    • (2010) Biochem. Pharmacol. , vol.79 , pp. 1036-1044
    • Novik, E.1    Maguire, T.J.2    Chao, P.3    Cheng, K.C.4    Yarmush, M.L.5
  • 11
    • 84897510737 scopus 로고    scopus 로고
    • In vitro generation of colonic epithelium from primary cells guided by microstructures
    • 1622-31
    • Wang Y, Ahmad A A, Sims C E, Magness S T and Allbritton N L 2014 In vitro generation of colonic epithelium from primary cells guided by microstructures Lab Chip 14 1622-31
    • (2014) Lab Chip , vol.14 , pp. 1622-1631
    • Wang, Y.1    Ahmad, A.A.2    Sims, C.E.3    Magness, S.T.4    Allbritton, N.L.5
  • 12
    • 77952958460 scopus 로고    scopus 로고
    • Long-term cultivation of HepG2 liver cells encapsulated in alginate hydrogels: A study of cell viability, morphology and drug metabolism
    • 1314-23
    • Lan S F, Safiejko-Mroczka B and Starly B 2010 Long-term cultivation of HepG2 liver cells encapsulated in alginate hydrogels: a study of cell viability, morphology and drug metabolism Toxicol. In Vitro 24 1314-23
    • (2010) Toxicol. in Vitro , vol.24 , pp. 1314-1323
    • Lan, S.F.1    Safiejko-Mroczka, B.2    Starly, B.3
  • 13
    • 84863101620 scopus 로고    scopus 로고
    • Cultured meat from stem cells: Challenges and prospects
    • 297-301
    • Post M J 2012 Cultured meat from stem cells: challenges and prospects Meat Sci. 92 297-301
    • (2012) Meat Sci. , vol.92 , pp. 297-301
    • Post, M.J.1
  • 14
    • 84922996872 scopus 로고    scopus 로고
    • Cell selective chitosan microparticles as injectable cell carriers for tissue regeneration
    • 23-31
    • Custodio C A, Cerqueira M T, Marques A P, Reis R L and Mano J F 2015 Cell selective chitosan microparticles as injectable cell carriers for tissue regeneration Biomaterials 43 23-31
    • (2015) Biomaterials , vol.43 , pp. 23-31
    • Custodio, C.A.1    Cerqueira, M.T.2    Marques, A.P.3    Reis, R.L.4    Mano, J.F.5
  • 15
    • 84913587910 scopus 로고    scopus 로고
    • NOTCH-mediated maintenance and expansion of human bone marrow stromal/stem cells: A technology designed for orthopedic regenerative medicine
    • 1456-66
    • Dong Y et al 2014 NOTCH-mediated maintenance and expansion of human bone marrow stromal/stem cells: a technology designed for orthopedic regenerative medicine Stem Cells Transl. Med. 3 1456-66
    • (2014) Stem Cells Transl. Med. , vol.3 , pp. 1456-1466
    • Dong, Y.1
  • 16
    • 84886499737 scopus 로고    scopus 로고
    • Concise review: Guidance in developing commercializable autologous/patient-specific cell therapy manufacturing
    • 871-83
    • Eaker S et al 2013 Concise review: guidance in developing commercializable autologous/patient-specific cell therapy manufacturing Stem Cells Transl. Med. 2 871-83
    • (2013) Stem Cells Transl. Med. , vol.2 , pp. 871-883
    • Eaker, S.1
  • 17
    • 84886536849 scopus 로고    scopus 로고
    • Concise review: Ex vivo expansion of cord blood-derived hematopoietic stem and progenitor cells: Basic principles, experimental approaches, and impact in regenerative medicine
    • 830-8
    • Flores-Guzman P, Fernandez-Sanchez V and Mayani H 2013 Concise review: ex vivo expansion of cord blood-derived hematopoietic stem and progenitor cells: basic principles, experimental approaches, and impact in regenerative medicine Stem Cells Transl. Med. 2 830-8
    • (2013) Stem Cells Transl. Med. , vol.2 , pp. 830-838
    • Flores-Guzman, P.1    Fernandez-Sanchez, V.2    Mayani, H.3
  • 18
    • 84921807245 scopus 로고    scopus 로고
    • Manufacturing road map for tissue engineering and regenerative medicine technologies
    • 130-5
    • Hunsberger J et al 2015 Manufacturing road map for tissue engineering and regenerative medicine technologies Stem Cells Transl. Med. 4 130-5
    • (2015) Stem Cells Transl. Med. , vol.4 , pp. 130-135
    • Hunsberger, J.1
  • 19
    • 83655212727 scopus 로고    scopus 로고
    • Large-scale expansion and exploitation of pluripotent stem cells for regenerative medicine purposes: Beyond the T flask
    • 71-84
    • Want A J, Nienow A W, Hewitt C J and Coopman K 2012 Large-scale expansion and exploitation of pluripotent stem cells for regenerative medicine purposes: beyond the T flask Regen. Med. 7 71-84
    • (2012) Regen. Med. , vol.7 , pp. 71-84
    • Want, A.J.1    Nienow, A.W.2    Hewitt, C.J.3    Coopman, K.4
  • 20
    • 84892506464 scopus 로고    scopus 로고
    • Stem cell engineering in bioreactors for large-scale bioprocessing
    • 4-15
    • Liu N, Zang R, Yang S and Li Y 2014 Stem cell engineering in bioreactors for large-scale bioprocessing Eng. Life Sci. 14 4-15
    • (2014) Eng. Life Sci. , vol.14 , pp. 4-15
    • Liu, N.1    Zang, R.2    Yang, S.3    Li, Y.4
  • 21
    • 64249114789 scopus 로고    scopus 로고
    • Stem cell bioprocessing: Fundamentals and principles
    • 209-32
    • Placzek M R et al 2009 Stem cell bioprocessing: fundamentals and principles J. R. Soc. Interface 6 209-32
    • (2009) J. R. Soc. Interface , vol.6 , pp. 209-232
    • Placzek, M.R.1
  • 22
    • 84921489555 scopus 로고    scopus 로고
    • Stem cell bioprocess engineering towards cGMP production and clinical applications
    • 709-22
    • Sart S, Schneider Y J, Li Y and Agathos S N 2014 Stem cell bioprocess engineering towards cGMP production and clinical applications Cytotechnology 66 709-22
    • (2014) Cytotechnology , vol.66 , pp. 709-722
    • Sart, S.1    Schneider, Y.J.2    Li, Y.3    Agathos, S.N.4
  • 23
    • 84901981400 scopus 로고    scopus 로고
    • Overcoming clinical hurdles for autologous pluripotent stem cell-based therapies
    • Byrne J A 2013 Overcoming clinical hurdles for autologous pluripotent stem cell-based therapies OA Stem Cells 1 3
    • (2013) OA Stem Cells , vol.1 , pp. 3
    • Byrne, J.A.1
  • 26
    • 78149330177 scopus 로고    scopus 로고
    • Three-dimensional culture systems for the expansion of pluripotent embryonic stem cells
    • 683-95
    • Storm M P, Orchard C B, Bone H K, Chaudhuri J B and Welham M J 2010 Three-dimensional culture systems for the expansion of pluripotent embryonic stem cells Biotechnol. Bioeng. 107 683-95
    • (2010) Biotechnol. Bioeng. , vol.107 , pp. 683-695
    • Storm, M.P.1    Orchard, C.B.2    Bone, H.K.3    Chaudhuri, J.B.4    Welham, M.J.5
  • 27
    • 84952861554 scopus 로고    scopus 로고
    • Optimization of agitation speed in spinner flask for microcarrier structural integrity and expansion of induced pluripotent stem cells
    • pp 1-15
    • Gupta P et al 2014 Optimization of agitation speed in spinner flask for microcarrier structural integrity and expansion of induced pluripotent stem cells Cytotechnology pp 1-15
    • (2014) Cytotechnology , pp. 1-15
    • Gupta, P.1
  • 28
    • 84923282732 scopus 로고    scopus 로고
    • Red blood cell generation by three-dimensional aggregate cultivation of late erythroblasts
    • 21(3-4) 817-28
    • Lee E, Han S Y, Choi H S, Chun B, Hwang B and Baek E J 2015 Red blood cell generation by three-dimensional aggregate cultivation of late erythroblasts Tissue Eng. A 21(3-4) 817-28
    • (2015) Tissue Eng. , vol.213 , Issue.4 , pp. 817-828
    • Lee, E.1    Han, S.Y.2    Choi, H.S.3    Chun, B.4    Hwang, B.5    Baek, E.J.6
  • 29
    • 84916204008 scopus 로고    scopus 로고
    • Chondrogenic differentiation of human adiposederived stem cells using microcarrier and bioreactor combination technique
    • 11(2) 1195-9
    • Kang H et al 2015 Chondrogenic differentiation of human adiposederived stem cells using microcarrier and bioreactor combination technique Mol. Med. Rep. 11(2) 1195-9
    • (2015) Mol. Med. Rep. , vol.112 , pp. 1195-1199
    • Kang, H.1
  • 30
    • 84908628009 scopus 로고    scopus 로고
    • Flow characterization of a spinner flask for induced pluripotent stem cell culture application
    • Ismadi M et al 2014 Flow characterization of a spinner flask for induced pluripotent stem cell culture application PLoS One 9 e106493
    • (2014) PLoS One , vol.9
    • Ismadi, M.1
  • 31
    • 84907444520 scopus 로고    scopus 로고
    • Encapsulating non-human primate multipotent stromal cells in alginate via high voltage for cell-based therapies and cryopreservation
    • Gryshkov O, Pogozhykh D, Hofmann N, Pogozhykh O, Mueller T and Glasmacher B 2014 Encapsulating non-human primate multipotent stromal cells in alginate via high voltage for cell-based therapies and cryopreservation PLoS One 9 e107911
    • (2014) PLoS One , vol.9
    • Gryshkov, O.1    Pogozhykh, D.2    Hofmann, N.3    Pogozhykh, O.4    Mueller, T.5    Glasmacher, B.6
  • 32
    • 84890589120 scopus 로고    scopus 로고
    • Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment
    • Chan H F, Zhang Y, Ho Y, Chiu Y, Jung Y and Leong K W 2013 Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment Sci. Rep. 3 3462
    • (2013) Sci. Rep. , vol.3 , pp. 3462
    • Chan, H.F.1    Zhang, Y.2    Ho, Y.3    Chiu, Y.4    Jung, Y.5    Leong, K.W.6
  • 33
    • 84898459014 scopus 로고    scopus 로고
    • Micro-mold design controls the 3D morphological evolution of self-assembling multicellular microtissues
    • 1134-44
    • Svoronos A A, Tejavibulya N, Schell J Y, Shenoy V B and Morgan J R 2014 Micro-mold design controls the 3D morphological evolution of self-assembling multicellular microtissues Tissue Eng. A 20 1134-44
    • (2014) Tissue Eng. , vol.20 , pp. 1134-1144
    • Svoronos, A.A.1    Tejavibulya, N.2    Schell, J.Y.3    Shenoy, V.B.4    Morgan, J.R.5
  • 34
    • 79952114647 scopus 로고    scopus 로고
    • Fabrication of three-dimensional porous cell-laden hydrogel for tissue engineering
    • Hwang C M et al 2010 Fabrication of three-dimensional porous cell-laden hydrogel for tissue engineering Biofabrication 2 035003
    • (2010) Biofabrication , vol.2 , Issue.3
    • Hwang, C.M.1
  • 35
    • 84896283272 scopus 로고    scopus 로고
    • Effects of coencapsulation of hepatocytes with adipose-derived stem cells in the treatment of rats with acute-on-chronic liver failure
    • 133-41
    • Zhang Y, Chen X M and Sun D L 2014 Effects of coencapsulation of hepatocytes with adipose-derived stem cells in the treatment of rats with acute-on-chronic liver failure Int. J. Artif. Organs 37 133-41
    • (2014) Int. J. Artif. Organs , vol.37 , pp. 133-141
    • Zhang, Y.1    Chen, X.M.2    Sun, D.L.3
  • 36
    • 84899532626 scopus 로고    scopus 로고
    • Human embryonic stem cell derived islet progenitors mature inside an encapsulation device without evidence of increased biomass or cell escape
    • 807-14
    • Kirk K, Hao E, Lahmy R and Itkin-Ansari P 2014 Human embryonic stem cell derived islet progenitors mature inside an encapsulation device without evidence of increased biomass or cell escape Stem Cell Res. 12 807-14
    • (2014) Stem Cell Res. , vol.12 , pp. 807-814
    • Kirk, K.1    Hao, E.2    Lahmy, R.3    Itkin-Ansari, P.4
  • 37
    • 84906567637 scopus 로고    scopus 로고
    • The synergistic effect of nanotopography and sustained dual release of hydrophobic and hydrophilic neurotrophic factors on human mesenchymal stem cell neuronal lineage commitment
    • 2151-61
    • Teo B K, Tan G D and Yim E K 2014 The synergistic effect of nanotopography and sustained dual release of hydrophobic and hydrophilic neurotrophic factors on human mesenchymal stem cell neuronal lineage commitment Tissue Eng. A 20 2151-61
    • (2014) Tissue Eng. , vol.20 , pp. 2151-2161
    • Teo, B.K.1    Tan, G.D.2    Yim, E.K.3
  • 38
    • 84903304410 scopus 로고    scopus 로고
    • Engineering articular cartilage-like grafts by self-assembly of infrapatellar fat pad-derived stem cells
    • 1686-98
    • Mesallati T, Buckley C T and Kelly D J 2014 Engineering articular cartilage-like grafts by self-assembly of infrapatellar fat pad-derived stem cells Biotechnol. Bioeng. 111 1686-98
    • (2014) Biotechnol. Bioeng. , vol.111 , pp. 1686-1698
    • Mesallati, T.1    Buckley, C.T.2    Kelly, D.J.3
  • 39
    • 79961158737 scopus 로고    scopus 로고
    • Microencapsulation technology: A powerful tool for integrating expansion and cryopreservation of human embryonic stem cells
    • Serra M et al 2011 Microencapsulation technology: a powerful tool for integrating expansion and cryopreservation of human embryonic stem cells PLoS One 6 e23212
    • (2011) PLoS One , vol.6
    • Serra, M.1
  • 40
    • 84903746950 scopus 로고    scopus 로고
    • Developing defined and scalable 3D culture systems for culturing human pluripotent stem cells at high densities
    • 172-83
    • Lei Y, Jeong D, Xiao J and Schaffer D V 2014 Developing defined and scalable 3D culture systems for culturing human pluripotent stem cells at high densities Cell Mol. Bioeng. 7 172-83
    • (2014) Cell Mol. Bioeng. , vol.7 , pp. 172-183
    • Lei, Y.1    Jeong, D.2    Xiao, J.3    Schaffer, D.V.4
  • 41
    • 78651513849 scopus 로고    scopus 로고
    • Cardiac cell generation from encapsulated embryonic stem cells in static and scalable culture systems
    • 1397-412
    • Jing D, Parikh A and Tzanakakis E S 2010 Cardiac cell generation from encapsulated embryonic stem cells in static and scalable culture systems Cell Transplant. 19 1397-412
    • (2010) Cell Transplant. , vol.19 , pp. 1397-1412
    • Jing, D.1    Parikh, A.2    Tzanakakis, E.S.3
  • 42
    • 84903814743 scopus 로고    scopus 로고
    • Efficient manufacturing of therapeutic mesenchymal stromal cells with the use of the quantum cell expansion system
    • 1048-58
    • Hanley P J et al 2014 Efficient manufacturing of therapeutic mesenchymal stromal cells with the use of the quantum cell expansion system Cytotherapy 16 1048-58
    • (2014) Cytotherapy , vol.16 , pp. 1048-1058
    • Hanley, P.J.1
  • 43
    • 84939997032 scopus 로고    scopus 로고
    • Three-dimensional spheroid culture of human umbilical cord mesenchymal stem cells promotes cell yield and stemness maintenance
    • 360(2) 297-307
    • Li Y et al 2015 Three-dimensional spheroid culture of human umbilical cord mesenchymal stem cells promotes cell yield and stemness maintenance Cell Tissue Res. 360(2) 297-307
    • (2015) Cell Tissue Res. , vol.3602 , pp. 297-307
    • Li, Y.1
  • 44
    • 84859188483 scopus 로고    scopus 로고
    • Scalable GMP compliant suspension culture system for human ES cells
    • 388-402
    • Chen V C et al 2012 Scalable GMP compliant suspension culture system for human ES cells Stem Cell Res. 8 388-402
    • (2012) Stem Cell Res. , vol.8 , pp. 388-402
    • Chen, V.C.1
  • 45
    • 84896813041 scopus 로고    scopus 로고
    • Suspension culture of pluripotent stem cells: Effect of shear on stem cell fate
    • 1-13
    • Keller K C, Rodrigues B and zur Nieden N I 2014 Suspension culture of pluripotent stem cells: effect of shear on stem cell fate Crit. Rev. Eukaryot. Gene Expr. 24 1-13
    • (2014) Crit. Rev. Eukaryot. Gene Expr. , vol.24 , pp. 1-13
    • Keller, K.C.1    Rodrigues, B.2    Zur Nieden, N.I.3
  • 46
    • 84888069210 scopus 로고    scopus 로고
    • Allogeneic cell therapy bioprocess economics and optimization: Single-use cell expansion technologies
    • 69-83
    • Simaria A S et al 2014 Allogeneic cell therapy bioprocess economics and optimization: single-use cell expansion technologies Biotechnol. Bioeng. 111 69-83
    • (2014) Biotechnol. Bioeng. , vol.111 , pp. 69-83
    • Simaria, A.S.1
  • 48
    • 84970878928 scopus 로고    scopus 로고
    • New wave agitation disposable bioreactors
    • Anonymous 1999 New wave agitation disposable bioreactors Pharmaceutical Prod. Techsource 14 33
    • (1999) Pharmaceutical Prod. Techsource , vol.14 , pp. 33
  • 49
    • 0032924570 scopus 로고    scopus 로고
    • Disposable bioreactor for cell culture using wave-induced agitation
    • 149-58
    • Singh V 1999 Disposable bioreactor for cell culture using wave-induced agitation Cytotechnology 30 149-58
    • (1999) Cytotechnology , vol.30 , pp. 149-158
    • Singh, V.1
  • 50
    • 70350497693 scopus 로고    scopus 로고
    • Clinical scale ex vivo manufacture of neutrophils from hematopoietic progenitor cells
    • 832-40
    • Timmins N E et al 2009 Clinical scale ex vivo manufacture of neutrophils from hematopoietic progenitor cells Biotechnol. Bioeng. 104 832-40
    • (2009) Biotechnol. Bioeng. , vol.104 , pp. 832-840
    • Timmins, N.E.1
  • 51
    • 74949105463 scopus 로고    scopus 로고
    • Bag bioreactor based on wave-induced motion: Characteristics and applications
    • 55-87
    • Eibl R, Werner S and Eibl D 2009 Bag bioreactor based on wave-induced motion: characteristics and applications Adv. Biochem. Eng. Biotechnol. 115 55-87
    • (2009) Adv. Biochem. Eng. Biotechnol. , vol.115 , pp. 55-87
    • Eibl, R.1    Werner, S.2    Eibl, D.3
  • 52
    • 11144257840 scopus 로고    scopus 로고
    • GMP production and testing of Xcellerated T Cells for the treatment of patients with CLL
    • 554-62
    • Hami L S, Green C, Leshinsky N, Markham E, Miller K and Craig S 2004 GMP production and testing of Xcellerated T Cells for the treatment of patients with CLL Cytotherapy 6 554-62
    • (2004) Cytotherapy , vol.6 , pp. 554-562
    • Hami, L.S.1    Green, C.2    Leshinsky, N.3    Markham, E.4    Miller, K.5    Craig, S.6
  • 53
    • 33746809465 scopus 로고    scopus 로고
    • Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media
    • 6074-87
    • Genzel Y, Olmer R M, Schafer B and Reichl U 2006 Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media Vaccine 24 6074-87
    • (2006) Vaccine , vol.24 , pp. 6074-6087
    • Genzel, Y.1    Olmer, R.M.2    Schafer, B.3    Reichl, U.4
  • 54
    • 77955656086 scopus 로고    scopus 로고
    • A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactor
    • 6256-64
    • Lohr V, Genzel Y, Behrendt I, Scharfenberg K and Reichl U 2010 A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactor Vaccine 28 6256-64
    • (2010) Vaccine , vol.28 , pp. 6256-6264
    • Lohr, V.1    Genzel, Y.2    Behrendt, I.3    Scharfenberg, K.4    Reichl, U.5
  • 55
    • 34247275657 scopus 로고    scopus 로고
    • Establishment of a mink enteritis vaccine production process in stirred-tank reactor and wave bioreactor microcarrier culture in 1-10 L scale
    • 3987-95
    • Hundt B, Best C, Schlawin N, Kassner H, Genzel Y and Reichl U 2007 Establishment of a mink enteritis vaccine production process in stirred-tank reactor and wave bioreactor microcarrier culture in 1-10 L scale Vaccine 25 3987-95
    • (2007) Vaccine , vol.25 , pp. 3987-3995
    • Hundt, B.1    Best, C.2    Schlawin, N.3    Kassner, H.4    Genzel, Y.5    Reichl, U.6
  • 56
    • 75349085710 scopus 로고    scopus 로고
    • Development of scalable culture systems for human embryonic stem cells
    • Azarin S M and Palecek S P 2010 Development of scalable culture systems for human embryonic stem cells Biochem. Eng. J. 48 378
    • (2010) Biochem. Eng. J. , vol.48 , pp. 378
    • Azarin, S.M.1    Palecek, S.P.2
  • 57
    • 84868016949 scopus 로고    scopus 로고
    • Bioprocess development for mass production of size-controlled human pluripotent stem cell aggregates in stirred suspension bioreactor
    • 831-51
    • Abbasalizadeh S, Larijani M R, Samadian A and Baharvand H 2012 Bioprocess development for mass production of size-controlled human pluripotent stem cell aggregates in stirred suspension bioreactor Tissue Eng. C 18 831-51
    • (2012) Tissue Eng. , vol.18 , pp. 831-851
    • Abbasalizadeh, S.1    Larijani, M.R.2    Samadian, A.3    Baharvand, H.4
  • 58
    • 79958258093 scopus 로고    scopus 로고
    • Efficient suspension bioreactor expansion of murine embryonic stem cells on microcarriers in serum-free medium
    • 811-23
    • Alfred R et al 2011 Efficient suspension bioreactor expansion of murine embryonic stem cells on microcarriers in serum-free medium Biotechnol. Prog. 27 811-23
    • (2011) Biotechnol. Prog. , vol.27 , pp. 811-823
    • Alfred, R.1
  • 59
    • 84904740002 scopus 로고    scopus 로고
    • Serum-free spheroid suspension culture maintains mesenchymal stem cell proliferation and differentiation potential
    • 974-83
    • Alimperti S, Lei P, Wen Y, Tian J, Campbell A M and Andreadis S T 2014 Serum-free spheroid suspension culture maintains mesenchymal stem cell proliferation and differentiation potential Biotechnol. Prog. 30 974-83
    • (2014) Biotechnol. Prog. , vol.30 , pp. 974-983
    • Alimperti, S.1    Lei, P.2    Wen, Y.3    Tian, J.4    Campbell, A.M.5    Andreadis, S.T.6
  • 60
    • 84899649027 scopus 로고    scopus 로고
    • A xenogeneic-free bioreactor system for the clinical-scale expansion of human mesenchymal stem/stromal cells
    • 1116-27
    • Dos Santos F et al 2014 A xenogeneic-free bioreactor system for the clinical-scale expansion of human mesenchymal stem/stromal cells Biotechnol. Bioeng. 111 1116-27
    • (2014) Biotechnol. Bioeng. , vol.111 , pp. 1116-1127
    • Dos Santos, F.1
  • 61
    • 80053909366 scopus 로고    scopus 로고
    • Cabral JMS. Scale-up of mouse embryonic stem cell expansion in stirred bioreactors
    • 1421-32
    • Fernandes-Platzgummer A, Diogo M M, Baptista R P and CLd S 2011 Cabral JMS. Scale-up of mouse embryonic stem cell expansion in stirred bioreactors Biotechnol. Prog. 27 1421-32
    • (2011) Biotechnol. Prog. , vol.27 , pp. 1421-1432
    • Fernandes-Platzgummer, A.1    Diogo, M.M.2    Baptista, R.P.3
  • 62
    • 77049125102 scopus 로고    scopus 로고
    • Scalable stirred-suspension bioreactor culture of human pluripotent stem cells
    • 405-21
    • Kehoe D E, Jing D, Lock L T and Tzanakakis E S 2010 Scalable stirred-suspension bioreactor culture of human pluripotent stem cells Tissue Eng. A 16 405-21
    • (2010) Tissue Eng. , vol.16 , pp. 405-421
    • Kehoe, D.E.1    Jing, D.2    Lock, L.T.3    Tzanakakis, E.S.4
  • 63
    • 84894146232 scopus 로고    scopus 로고
    • Facile engineering of xeno-free microcarriers for the scalable cultivation of human pluripotent stem cells in stirred suspension
    • 20(3-4) 588-99
    • Fan Y, Hsiung M, Cheng C and Tzanakakis E S 2014 Facile engineering of xeno-free microcarriers for the scalable cultivation of human pluripotent stem cells in stirred suspension Tissue Eng. A 20(3-4) 588-99
    • (2014) Tissue Eng. , vol.203 , Issue.4 , pp. 588-599
    • Fan, Y.1    Hsiung, M.2    Cheng, C.3    Tzanakakis, E.S.4
  • 64
    • 84865309469 scopus 로고    scopus 로고
    • Suspension culture of human pluripotent stem cells in controlled, stirred bioreactors
    • 772-84
    • Olmer R et al 2012 Suspension culture of human pluripotent stem cells in controlled, stirred bioreactors Tissue Eng. C 18 772-84
    • (2012) Tissue Eng. , vol.18 , pp. 772-784
    • Olmer, R.1
  • 65
    • 84896342081 scopus 로고    scopus 로고
    • Hepatic differentiation of human embryonic stem cells on microcarriers
    • 39-48
    • Park Y, Chen Y, Ordovas L and Verfaillie C M 2014 Hepatic differentiation of human embryonic stem cells on microcarriers J. Biotechnol. 174 39-48
    • (2014) J. Biotechnol. , vol.174 , pp. 39-48
    • Park, Y.1    Chen, Y.2    Ordovas, L.3    Verfaillie, C.M.4
  • 66
    • 84879840462 scopus 로고    scopus 로고
    • Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor
    • 1233-45
    • Rafiq Q A, Brosnan K M, Coopman K, Nienow A W and Hewitt C J 2013 Culture of human mesenchymal stem cells on microcarriers in a 5 l stirred-tank bioreactor Biotechnol. Lett. 35 1233-45
    • (2013) Biotechnol. Lett. , vol.35 , pp. 1233-1245
    • Rafiq, Q.A.1    Brosnan, K.M.2    Coopman, K.3    Nienow, A.W.4    Hewitt, C.J.5
  • 67
    • 81355134650 scopus 로고    scopus 로고
    • Toward a clinical-grade expansion of mesenchymal stem cells from human sources: A microcarrier-based culture system under xeno-free conditions
    • 1201-10
    • Santos F D et al 2011 Toward a clinical-grade expansion of mesenchymal stem cells from human sources: a microcarrier-based culture system under xeno-free conditions Tissue Eng. C 17 1201-10
    • (2011) Tissue Eng. , vol.17 , pp. 1201-1210
    • Santos, F.D.1
  • 68
    • 84923112636 scopus 로고    scopus 로고
    • Scalable ex vivo expansion of human mesenchymal stem/stromal cells in microcarrier-based stirred culture systems
    • 147-59
    • Carmelo J G, Fernandes-Platzgummer A, Cabral J M and da Silva C L 2015 Scalable ex vivo expansion of human mesenchymal stem/stromal cells in microcarrier-based stirred culture systems Methods Mol. Biol. 1283 147-59
    • (2015) Methods Mol. Biol. , vol.1283 , pp. 147-159
    • Carmelo, J.G.1    Fernandes-Platzgummer, A.2    Cabral, J.M.3    Da Silva, C.L.4
  • 69
    • 33644821605 scopus 로고    scopus 로고
    • Differentiation and lineage selection of mouse embryonic stem cells in a stirred bench scale bioreactor with automated process control
    • 920-33
    • Schroeder M et al 2005 Differentiation and lineage selection of mouse embryonic stem cells in a stirred bench scale bioreactor with automated process control Biotechnol. Bioeng. 92 920-33
    • (2005) Biotechnol. Bioeng. , vol.92 , pp. 920-933
    • Schroeder, M.1
  • 71
    • 0027561450 scopus 로고
    • Expansion and differentiation of human hematopoietic cells from static cultures through small-scale bioreactors
    • 131-7
    • Sardonini C A and Wu Y J 1993 Expansion and differentiation of human hematopoietic cells from static cultures through small-scale bioreactors Biotechnol. Prog. 9 131-7
    • (1993) Biotechnol. Prog. , vol.9 , pp. 131-137
    • Sardonini, C.A.1    Wu, Y.J.2
  • 72
    • 41549164762 scopus 로고    scopus 로고
    • Design of bioreactors for mesenchymal stem cell tissue engineering
    • 408-20
    • Godara P, McFarland C D and Nordon R E 2008 Design of bioreactors for mesenchymal stem cell tissue engineering Chem. Technol. Biotechnol. 83 408-20
    • (2008) Chem. Technol. Biotechnol. , vol.83 , pp. 408-420
    • Godara, P.1    McFarland, C.D.2    Nordon, R.E.3
  • 73
    • 84859959244 scopus 로고    scopus 로고
    • Phenotypic and functional characterization of human bone marrow stromal cells in hollow fiber bioreactors
    • 369-77
    • Li M et al 2012 Phenotypic and functional characterization of human bone marrow stromal cells in hollow fiber bioreactors J. Tissue Eng. Regen. Med. 6 369-77
    • (2012) J. Tissue Eng. Regen. Med. , vol.6 , pp. 369-377
    • Li, M.1
  • 74
    • 84903782373 scopus 로고    scopus 로고
    • The hollow fiber bioreactor as a stroma-supported, serum-free ex vivo expansion platform for human umbilical cord blood cells
    • 980-9
    • Xue C, Kwek K Y, Chan J K, Chen Q and Lim M 2014 The hollow fiber bioreactor as a stroma-supported, serum-free ex vivo expansion platform for human umbilical cord blood cells Biotechnol. J. 9 980-9
    • (2014) Biotechnol. J. , vol.9 , pp. 980-989
    • Xue, C.1    Kwek, K.Y.2    Chan, J.K.3    Chen, Q.4    Lim, M.5
  • 75
    • 84872405664 scopus 로고    scopus 로고
    • Good manufacturing practice-compliant animal-free expansion of human bone marrow derived mesenchymal stroma cells in a closed hollow-fiber-based bioreactor
    • 325-30
    • Nold P, Brendel C, Neubauer A, Bein G and Hackstein H 2013 Good manufacturing practice-compliant animal-free expansion of human bone marrow derived mesenchymal stroma cells in a closed hollow-fiber-based bioreactor Biochem. Biophys. Res. Commun. 430 325-30
    • (2013) Biochem. Biophys. Res. Commun. , vol.430 , pp. 325-330
    • Nold, P.1    Brendel, C.2    Neubauer, A.3    Bein, G.4    Hackstein, H.5
  • 76
    • 84868483902 scopus 로고    scopus 로고
    • Scale-up of human embryonic stem cell culture using a hollow fibre bioreactor
    • 2307-15
    • Roberts I et al 2012 Scale-up of human embryonic stem cell culture using a hollow fibre bioreactor Biotechnol. Lett. 34 2307-15
    • (2012) Biotechnol. Lett. , vol.34 , pp. 2307-2315
    • Roberts, I.1
  • 77
    • 84886418978 scopus 로고    scopus 로고
    • GMP-compliant isolation and expansion of bone marrow-derived MSCs in the closed, automated device quantum cell expansion system
    • 1981-2000
    • Rojewski M T et al 2013 GMP-compliant isolation and expansion of bone marrow-derived MSCs in the closed, automated device quantum cell expansion system Cell Transplant. 22 1981-2000
    • (2013) Cell Transplant. , vol.22 , pp. 1981-2000
    • Rojewski, M.T.1
  • 78
    • 23644448920 scopus 로고    scopus 로고
    • Bioreactors for tissue mass culture: Design, characterization, and recent advances
    • 7481-503
    • Martin Y and Vermette P 2005 Bioreactors for tissue mass culture: design, characterization, and recent advances Biomaterials 26 7481-503
    • (2005) Biomaterials , vol.26 , pp. 7481-7503
    • Martin, Y.1    Vermette, P.2
  • 79
    • 79960982719 scopus 로고    scopus 로고
    • Integration of hollow fiber membranes improves nutrient supply in three-dimensional tissue constructs
    • 3312-24
    • Bettahalli N M et al 2011 Integration of hollow fiber membranes improves nutrient supply in three-dimensional tissue constructs Acta Biomater. 7 3312-24
    • (2011) Acta Biomater. , vol.7 , pp. 3312-3324
    • Bettahalli, N.M.1
  • 80
    • 84893780873 scopus 로고    scopus 로고
    • Visualizing medium and biodistribution in complex cell culture bioreactors using in vivo imaging
    • 256-60
    • Ratcliffe E, Thomas R J and Stacey A J 2014 Visualizing medium and biodistribution in complex cell culture bioreactors using in vivo imaging Biotechnol. Prog. 30 256-60
    • (2014) Biotechnol. Prog. , vol.30 , pp. 256-260
    • Ratcliffe, E.1    Thomas, R.J.2    Stacey, A.J.3
  • 81
    • 84862909080 scopus 로고    scopus 로고
    • Compartmental hollow fiber capillary membrane-based bioreactor technology for in vitro studies on red blood cell lineage direction of hematopoietic stem cells
    • 133-42
    • Housler G J et al 2012 Compartmental hollow fiber capillary membrane-based bioreactor technology for in vitro studies on red blood cell lineage direction of hematopoietic stem cells Tissue Eng. C 18 133-42
    • (2012) Tissue Eng. , vol.18 , pp. 133-142
    • Housler, G.J.1
  • 82
    • 80655132019 scopus 로고    scopus 로고
    • NASA-approved rotary bioreactor enhances proliferation of human epidermal stem cells and supports formation of 3D epidermis-like structure
    • 6(11)
    • Lei X et al 2011 NASA-approved rotary bioreactor enhances proliferation of human epidermal stem cells and supports formation of 3D epidermis-like structure PLoS One 6(11) e26603
    • (2011) PLoS One , vol.611 , pp. e26603
    • Lei, X.1
  • 83
    • 84951608143 scopus 로고
    • Three-dimensional modeling of T-24 human bladder carcinoma cell line: A new simulated microgravity culture vessel
    • 29-36
    • Prewett T, Goodwin T and Spaulding G 1993 Three-dimensional modeling of T-24 human bladder carcinoma cell line: a new simulated microgravity culture vessel J. Tissue Cult. Methods 15 29-36
    • (1993) J. Tissue Cult. Methods , vol.15 , pp. 29-36
    • Prewett, T.1    Goodwin, T.2    Spaulding, G.3
  • 84
    • 0030974462 scopus 로고    scopus 로고
    • Three-dimensional culture of a mixed mullerian tumor of the ovary: Expression of in vivo characteristics
    • 366-74
    • Goodwin T J, Prewett T L, Spaulding G F and Becker J L 1997 Three-dimensional culture of a mixed mullerian tumor of the ovary: expression of in vivo characteristics In Vitro Cell Dev. Biol. Anim. 33 366-74
    • (1997) Vitro Cell Dev. Biol. Anim. , vol.33 , pp. 366-374
    • Goodwin, T.J.1    Prewett, T.L.2    Spaulding, G.F.3    Becker, J.L.4
  • 85
    • 34548131287 scopus 로고    scopus 로고
    • Morphological characteristics and proliferation of keratocytes cultured under simulated microgravity
    • 722-31
    • Chen J, Chen R and Gao S 2007 Morphological characteristics and proliferation of keratocytes cultured under simulated microgravity Artif. Organs. 31 722-31
    • (2007) Artif. Organs. , vol.31 , pp. 722-731
    • Chen, J.1    Chen, R.2    Gao, S.3
  • 86
    • 77955000681 scopus 로고    scopus 로고
    • Dynamic three-dimensional culture methods enhance mesenchymal stem cell properties and increase therapeutic potential
    • 735-49
    • Frith J E, Thomson B and Genever P G 2010 Dynamic three-dimensional culture methods enhance mesenchymal stem cell properties and increase therapeutic potential Tissue Eng. C 16 735-49
    • (2010) Tissue Eng. , vol.16 , pp. 735-749
    • Frith, J.E.1    Thomson, B.2    Genever, P.G.3
  • 87
    • 47049105384 scopus 로고    scopus 로고
    • Three-dimensional fabrication of engineered bone with human bio-derived bone scaffolds in a rotating wall vessel bioreactor
    • 323-32
    • Song K, Liu T, Cui Z, Li X and Ma X 2008 Three-dimensional fabrication of engineered bone with human bio-derived bone scaffolds in a rotating wall vessel bioreactor J. Biomed. Mater. Res. A 86 323-32
    • (2008) J. Biomed. Mater. Res. , vol.86 , pp. 323-332
    • Song, K.1    Liu, T.2    Cui, Z.3    Li, X.4    Ma, X.5
  • 89
    • 84913570381 scopus 로고    scopus 로고
    • Early exposure of murine embryonic stem cells to hematopoietic cytokines differentially directs definitive erythropoiesis and cardiomyogenesis in alginate hydrogel three-dimensional cultures
    • 2720-9
    • Fauzi I, Panoskaltsis N and Mantalaris A 2014 Early exposure of murine embryonic stem cells to hematopoietic cytokines differentially directs definitive erythropoiesis and cardiomyogenesis in alginate hydrogel three-dimensional cultures Stem Cells Dev. 23 2720-9
    • (2014) Stem Cells Dev. , vol.23 , pp. 2720-2729
    • Fauzi, I.1    Panoskaltsis, N.2    Mantalaris, A.3
  • 90
    • 84911983570 scopus 로고    scopus 로고
    • Simulated microgravity affects chondrogenesis and hypertrophy of human mesenchymal stem cells
    • 2615-21
    • Mayer-Wagner S et al 2014 Simulated microgravity affects chondrogenesis and hypertrophy of human mesenchymal stem cells Int. Orthop. 38 2615-21
    • (2014) Int. Orthop. , vol.38 , pp. 2615-2621
    • Mayer-Wagner, S.1
  • 91
    • 79960621058 scopus 로고    scopus 로고
    • Bioreactor systems for bone tissue engineering
    • 263-80
    • Rauh J, Milan F, Gunther K P and Stiehler M 2011 Bioreactor systems for bone tissue engineering Tissue Eng. B 17 263-80
    • (2011) Tissue Eng. , vol.17 , pp. 263-280
    • Rauh, J.1    Milan, F.2    Gunther, K.P.3    Stiehler, M.4
  • 92
    • 84973417097 scopus 로고    scopus 로고
    • Bioreactor systems for human bone tissue engineering
    • 06 494-525
    • Sladkova M and de Peppo G M 2014 06 Bioreactor systems for human bone tissue engineering Processes 2 494-525
    • (2014) Processes , vol.2 , pp. 494-525
    • Sladkova, M.1    De Peppo, G.M.2
  • 93
    • 33745484771 scopus 로고    scopus 로고
    • Ex vivo expansion of hematopoietic stem cells derived from umbilical cord blood in rotating wall vessel
    • 592-601
    • Liu Y, Liu T, Fan X, Ma X and Cui Z 2006 Ex vivo expansion of hematopoietic stem cells derived from umbilical cord blood in rotating wall vessel J. Biotechnol. 124 592-601
    • (2006) J. Biotechnol. , vol.124 , pp. 592-601
    • Liu, Y.1    Liu, T.2    Fan, X.3    Ma, X.4    Cui, Z.5
  • 94
    • 0027908934 scopus 로고
    • Packed bed bioreactor with porous ceramic beads for animal cell culture
    • 25-34
    • Park S and Stephanopoulos G 1993 Packed bed bioreactor with porous ceramic beads for animal cell culture Biotechnol. Bioeng. 41 25-34
    • (1993) Biotechnol. Bioeng. , vol.41 , pp. 25-34
    • Park, S.1    Stephanopoulos, G.2
  • 95
    • 0344242003 scopus 로고    scopus 로고
    • Development of a fixed bed bioreactor for the expansion of human hematopoietic progenitor cells
    • 227-34
    • Meissner P, Schroder B, Herfurth C and Biselli M 1999 Development of a fixed bed bioreactor for the expansion of human hematopoietic progenitor cells Cytotechnology 30 227-34
    • (1999) Cytotechnology , vol.30 , pp. 227-234
    • Meissner, P.1    Schroder, B.2    Herfurth, C.3    Biselli, M.4
  • 97
    • 84896965671 scopus 로고    scopus 로고
    • Expansion of embryonic stem cells in suspension and fibrous bed bioreactors
    • 54-64
    • Liu N, Li Y and Yang S 2014 Expansion of embryonic stem cells in suspension and fibrous bed bioreactors J. Biotechnol. 178 54-64
    • (2014) J. Biotechnol. , vol.178 , pp. 54-64
    • Liu, N.1    Li, Y.2    Yang, S.3
  • 98
    • 27944510690 scopus 로고    scopus 로고
    • Why tissue engineering needs process engineering
    • 1353-5
    • Archer R and Williams D J 2005 Why tissue engineering needs process engineering Nat. Biotech. 23 1353-5
    • (2005) Nat. Biotech. , vol.23 , pp. 1353-1355
    • Archer, R.1    Williams, D.J.2
  • 99
    • 84899478439 scopus 로고    scopus 로고
    • A review of the effects of the cell environment physicochemical nanoarchitecture on stem cell commitment
    • 5278-93
    • Das R K and Zouani O F 2014 A review of the effects of the cell environment physicochemical nanoarchitecture on stem cell commitment Biomaterials 35 5278-93
    • (2014) Biomaterials , vol.35 , pp. 5278-5293
    • Das, R.K.1    Zouani, O.F.2
  • 100
    • 84901456044 scopus 로고    scopus 로고
    • Nanofibrous gelatin substrates for long-term expansion of human pluripotent stem cells
    • 6259-67
    • Liu L et al 2014 Nanofibrous gelatin substrates for long-term expansion of human pluripotent stem cells Biomaterials 35 6259-67
    • (2014) Biomaterials , vol.35 , pp. 6259-6267
    • Liu, L.1
  • 101
    • 84898797275 scopus 로고    scopus 로고
    • Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation
    • 5580-5
    • Dixon J E et al 2014 Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation Proc. Natl Acad. Sci. 111 5580-5
    • (2014) Proc. Natl Acad. Sci. , vol.111 , pp. 5580-5585
    • Dixon, J.E.1
  • 102
    • 80053969704 scopus 로고    scopus 로고
    • Osteoinduction of human mesenchymal stem cells by bioactive composite scaffolds without supplemental osteogenic growth factors
    • Polini A, Pisignano D, Parodi M, Quarto R and Scaglione S 2011 Osteoinduction of human mesenchymal stem cells by bioactive composite scaffolds without supplemental osteogenic growth factors PLoS One 6 e26211
    • (2011) PLoS One , vol.6
    • Polini, A.1    Pisignano, D.2    Parodi, M.3    Quarto, R.4    Scaglione, S.5
  • 103
    • 84908498335 scopus 로고    scopus 로고
    • Stable biofunctionalization of hydroxyapatite (HA) surfaces by HA-binding/osteogenic modular peptides for inducing osteogenic differentiation of mesenchymal stem cells
    • Stable biofunctionalization of hydroxyapatite (HA) surfaces by HA-binding/osteogenic modular peptides for inducing osteogenic differentiation of mesenchymal stem cells 1779-86
    • Polini A, Wang J, Bai H, Zhu Y, Tomsia A, P and Mao C 2014 Stable biofunctionalization of hydroxyapatite (HA) surfaces by HA-binding/osteogenic modular peptides for inducing osteogenic differentiation of mesenchymal stem cells Biomater. Sci. 2 1779-86
    • (2014) Biomater. Sci. , vol.2 , pp. 1779-1786
    • Polini, A.1    Wang, J.2    Bai, H.3    Zhu, Y.4    Tomsia, A.P.5    Mao, C.6
  • 104
    • 84874571044 scopus 로고    scopus 로고
    • Raman spectroscopy in biomedicine - Non-invasive in vitro analysis of cells and extracellular matrix components in tissues
    • 288-97
    • Brauchle E and Schenke-Layland K 2013 Raman spectroscopy in biomedicine - non-invasive in vitro analysis of cells and extracellular matrix components in tissues Biotechnol. J. 8 288-97
    • (2013) Biotechnol. J. , vol.8 , pp. 288-297
    • Brauchle, E.1    Schenke-Layland, K.2
  • 107
    • 84929056256 scopus 로고    scopus 로고
    • Recent advances in application of biosensors in tissue engineering
    • 2014
    • Hasan A et al 2014 Recent advances in application of biosensors in tissue engineering Biomed. Res. Int. 2014 307519
    • (2014) Biomed. Res. Int. , vol.2014
    • Hasan, A.1
  • 108
    • 84881155671 scopus 로고    scopus 로고
    • Stricter standards sought to curb stem-cell confusion
    • Shen H 2013 Stricter standards sought to curb stem-cell confusion Nature 499 389
    • (2013) Nature , vol.499 , pp. 389
    • Shen, H.1
  • 110
    • 84887116253 scopus 로고    scopus 로고
    • Automated microscopy as a quantitative method to measure differences in adipogenic differentiation in preparations of human mesenchymal stromal cells
    • 1527-40
    • Lo Surdo J L, Millis B A and Bauer S R 2013 Automated microscopy as a quantitative method to measure differences in adipogenic differentiation in preparations of human mesenchymal stromal cells Cytotherapy 15 1527-40
    • (2013) Cytotherapy , vol.15 , pp. 1527-1540
    • Lo Surdo, J.L.1    Millis, B.A.2    Bauer, S.R.3
  • 111
    • 84907030987 scopus 로고    scopus 로고
    • Improved reproducibility by assuring confidence in measurements in biomedical research
    • 895-8
    • Plant A L, Locascio L E, May W E and Gallagher P D 2014 Improved reproducibility by assuring confidence in measurements in biomedical research Nat. Methods 11 895-8
    • (2014) Nat. Methods , vol.11 , pp. 895-898
    • Plant, A.L.1    Locascio, L.E.2    May, W.E.3    Gallagher, P.D.4


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