메뉴 건너뛰기




Volumn 7, Issue 2, 2014, Pages 172-183

Developing defined and scalable 3D culture systems for culturing human pluripotent stem cells at high densities

Author keywords

3D culture system; Human embryonic stem cells; Induced pluripotent stem cells; Thermoreversible hydrogel

Indexed keywords

ARTICLE; CELL AGGLOMERATION; CELL AGGREGATION; CELL DENSITY; CELL DIFFERENTIATION; CELL EXPANSION; CELL GROWTH; CELL LINEAGE; CELL LOSS; CELL VIABILITY; CELLULAR PARAMETERS; CULTURE TECHNIQUE; GOOD MANUFACTURING PRACTICE; HUMAN; HUMAN CELL; HYDROGEL; LIQUID CULTURE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; STEM CELL CULTURE; THERMODYNAMICS;

EID: 84903746950     PISSN: 18655025     EISSN: 18655033     Source Type: Journal    
DOI: 10.1007/s12195-014-0333-z     Document Type: Article
Times cited : (67)

References (42)
  • 1
    • 79955539044 scopus 로고    scopus 로고
    • Dynamic suspension culture for scalable expansion of undifferentiated human pluripotent stem cells
    • Amit, M., I. Laevsky, Y. Miropolsky, K. Shariki, M. Peri, and J. Itskovitz-Eldor. Dynamic suspension culture for scalable expansion of undifferentiated human pluripotent stem cells. Nat. Protoc. 6:572-579, 2011.
    • (2011) Nat. Protoc. , vol.6 , pp. 572-579
    • Amit, M.1    Laevsky, I.2    Miropolsky, Y.3    Shariki, K.4    Peri, M.5    Itskovitz-Eldor, J.6
  • 2
    • 79960351640 scopus 로고    scopus 로고
    • Whole-organ tissue engineering: Decellularization and recellularization of three-dimensional matrix scaffolds
    • Badylak, S. F., D. Taylor, and K. Uygun. Whole-organ tissue engineering: decellularization and recellularization of three-dimensional matrix scaffolds. Annu. Rev. Biomed. Eng. 13:27-53, 2011.
    • (2011) Annu. Rev. Biomed. Eng. , vol.13 , pp. 27-53
    • Badylak, S.F.1    Taylor, D.2    Uygun, K.3
  • 3
    • 70449093715 scopus 로고    scopus 로고
    • Biomaterials Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm
    • Chayosumrit, M., B. Tuch, and K. Sidhu. Biomaterials Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm. Biomaterials 31:505-514, 2010.
    • (2010) Biomaterials , vol.31 , pp. 505-514
    • Chayosumrit, M.1    Tuch, B.2    Sidhu, K.3
  • 4
    • 79960288995 scopus 로고    scopus 로고
    • Critical microcarrier properties affecting the expansion of undifferentiated human embryonic stem cells
    • Chen, A. K., et al. Critical microcarrier properties affecting the expansion of undifferentiated human embryonic stem cells. Stem Cell Res. 7:97-111, 2011.
    • (2011) Stem Cell Res. , vol.7 , pp. 97-111
    • Chen, A.K.1
  • 5
    • 79955611823 scopus 로고    scopus 로고
    • Chemically defined conditions for human iPSC derivation and culture
    • Chen, G., et al. Chemically defined conditions for human iPSC derivation and culture. Nat. Methods 8:424-429, 2011.
    • (2011) Nat. Methods , vol.8 , pp. 424-429
    • Chen, G.1
  • 6
    • 84859188483 scopus 로고    scopus 로고
    • Scalable GMP compliant suspension culture system for human ES cells
    • Chen, V. C., et al. Scalable GMP compliant suspension culture system for human ES cells. Stem Cell Res. 8:388-402, 2012.
    • (2012) Stem Cell Res. , vol.8 , pp. 388-402
    • Chen, V.C.1
  • 7
    • 84872013374 scopus 로고    scopus 로고
    • Adapting human pluripotent stem cells to high-throughput and high-content screening
    • Desbordes, S. C., and L. Studer. Adapting human pluripotent stem cells to high-throughput and high-content screening. Nat. Protoc. 8:111-130, 2012.
    • (2012) Nat. Protoc. , vol.8 , pp. 111-130
    • Desbordes, S.C.1    Studer, L.2
  • 8
    • 27144526161 scopus 로고    scopus 로고
    • Shear-controlled single-step mouse embryonic stem cell expansion and embryoid body-based differentiation
    • DOI 10.1634/stemcells.2005-0112
    • Fok, E. Y. L., and P. W. Zandstra. Shear-controlled single-step mouse embryonic stem cell expansion and embryoid body-based differentiation. Stem Cells 23:1333-1342, 2005. (Pubitemid 41504921)
    • (2005) Stem Cells , vol.23 , Issue.9 , pp. 1333-1342
    • Fok, E.Y.L.1    Zandstra, P.W.2
  • 9
    • 84890439421 scopus 로고    scopus 로고
    • Derivation of novel human ground state naive pluripotent stem cells
    • Gafni, O., et al. Derivation of novel human ground state naive pluripotent stem cells. Nature 504:282-286, 2013.
    • (2013) Nature , vol.504 , pp. 282-286
    • Gafni, O.1
  • 11
    • 23944479376 scopus 로고    scopus 로고
    • Molecular mechanism of apoptosis induced by mechanical forces
    • Hsieh, M. H., and H. T. Nguyen. Molecular mechanism of apoptosis induced by mechanical forces. Int. Rev. Cytol. 245:45-90, 2005.
    • (2005) Int. Rev. Cytol. , vol.245 , pp. 45-90
    • Hsieh, M.H.1    Nguyen, H.T.2
  • 12
    • 16244400050 scopus 로고    scopus 로고
    • TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
    • DOI 10.1242/dev.01706
    • James, D., A. J. Levine, D. Besser, and A. Hemmati-Brivanlou. TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 132:1273-1282, 2005. (Pubitemid 40528787)
    • (2005) Development , vol.132 , Issue.6 , pp. 1273-1282
    • James, D.1    Levine, A.J.2    Besser, D.3    Hemmati-Brivanlou, A.4
  • 13
    • 77049125102 scopus 로고    scopus 로고
    • Scalable stirred-suspension bioreactor culture of human pluripotent stem cells
    • Kehoe, D. E., D. Jing, L. T. Lock, and E. S. Tzanakakis. Scalable stirred-suspension bioreactor culture of human pluripotent stem cells. Tissue Eng. Part A 16, 2010.
    • (2010) Tissue Eng. Part A , vol.16
    • Kehoe, D.E.1    Jing, D.2    Lock, L.T.3    Tzanakakis, E.S.4
  • 14
    • 84355166561 scopus 로고    scopus 로고
    • Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease
    • Kriks, S., et al. Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 480:547-551, 2011.
    • (2011) Nature , vol.480 , pp. 547-551
    • Kriks, S.1
  • 15
    • 24944496766 scopus 로고    scopus 로고
    • Regenerating the heart
    • DOI 10.1038/nbt1117
    • Laflamme, M. A., and C. E. Murry. Regenerating the heart. Nat. Biotechnol. 23:845-856, 2005. (Pubitemid 43093128)
    • (2005) Nature Biotechnology , vol.23 , Issue.7 , pp. 845-856
    • Laflamme, M.A.1    Murry, C.E.2
  • 16
    • 78349306393 scopus 로고    scopus 로고
    • The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels
    • Lei, Y., S. Gojgini, J. Lam, and T. Segura. The spreading, migration and proliferation of mouse mesenchymal stem cells cultured inside hyaluronic acid hydrogels. Biomaterials 32:39-47, 2011.
    • (2011) Biomaterials , vol.32 , pp. 39-47
    • Lei, Y.1    Gojgini, S.2    Lam, J.3    Segura, T.4
  • 17
    • 84891352376 scopus 로고    scopus 로고
    • A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation
    • Lei, Y., and D. V. Schaffer. A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation. Proc. Natl Acad. Sci. U.S.A. 1-10, 2013.
    • (2013) Proc. Natl Acad. Sci. U.S.A. , pp. 1-10
    • Lei, Y.1    Schaffer, D.V.2
  • 18
    • 3142521479 scopus 로고    scopus 로고
    • Stem cell therapy for human neurodegenerative disorders - How to make it work
    • DOI 10.1038/nm1064
    • Lindvall, O., Z. Kokaia, and A. Martinez-Serrano. Stem cell therapy for human neurodegenerative disorders-how to make it work. Nat. Med. 10:S42-S50, 2004. (Pubitemid 38901866)
    • (2004) Nature Medicine , vol.10 , Issue.SUPPL.
    • Lindvall, O.1    Kokaia, Z.2    Martinez-Serrano, A.3
  • 19
    • 53049090478 scopus 로고    scopus 로고
    • Innovation in the culture and derivation of pluripotent human stem cells
    • McDevitt, T. C., and S. P. Palecek. Innovation in the culture and derivation of pluripotent human stem cells. Curr. Opin. Biotechnol. 19:527-533, 2008.
    • (2008) Curr. Opin. Biotechnol. , vol.19 , pp. 527-533
    • McDevitt, T.C.1    Palecek, S.P.2
  • 20
    • 0347135824 scopus 로고    scopus 로고
    • Embryonic stem cells in drug discovery
    • McNeish, J. Embryonic stem cells in drug discovery. Nat. Rev. Drug Discov. 3:70-80, 2004. (Pubitemid 38088699)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.1 , pp. 70-80
    • McNeish, J.1
  • 21
    • 77958609405 scopus 로고    scopus 로고
    • Abrogation of E-cadherin-mediated cellular aggregation allows proliferation of pluripotent mouse embryonic stem cells in shake flask bioreactors
    • Mohamet, L., M. L. Lea, and C. M. Ward. Abrogation of E-cadherin-mediated cellular aggregation allows proliferation of pluripotent mouse embryonic stem cells in shake flask bioreactors. PLoS One 5:e12921, 2010.
    • (2010) PLoS One , vol.5
    • Mohamet, L.1    Lea, M.L.2    Ward, C.M.3
  • 22
    • 64549145534 scopus 로고    scopus 로고
    • P.S. Scalable culture and cryopreservation of human embryonic stem cells on microcarriers
    • Nie, Y., V. Bergendahl, D. J. Hei, and J. M. Jones. P.S. scalable culture and cryopreservation of human embryonic stem cells on microcarriers. Biotechnol. Prog. 25:20-31, 2009.
    • (2009) Biotechnol. Prog. , vol.25 , pp. 20-31
    • Nie, Y.1    Bergendahl, V.2    Hei, D.J.3    Jones, J.M.4
  • 23
    • 79955525831 scopus 로고    scopus 로고
    • Lonely death dance of human pluripotent stem cells: ROCKing between metastable cell states
    • Ohgushi, M., and Y. Sasai. Lonely death dance of human pluripotent stem cells: ROCKing between metastable cell states. Trends Cell Biol. 21:274-282, 2011.
    • (2011) Trends Cell Biol. , vol.21 , pp. 274-282
    • Ohgushi, M.1    Sasai, Y.2
  • 24
    • 77956243773 scopus 로고    scopus 로고
    • Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells
    • Ohgushi, M., et al. Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells. Cell Stem Cell 7:225-239, 2010.
    • (2010) Cell Stem Cell , vol.7 , pp. 225-239
    • Ohgushi, M.1
  • 25
    • 38049187707 scopus 로고    scopus 로고
    • Reprogramming of human somatic cells to pluripotency with defined factors
    • Park, I.-H., et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451:141-146, 2008.
    • (2008) Nature , vol.451 , pp. 141-146
    • Park, I.-H.1
  • 27
    • 84855353573 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2012 update: A report from the American Heart Association
    • Roger, V. L., et al. Heart disease and stroke statistics-2012 update: a report from the American Heart Association. Circulation 125:e2-e220, 2012.
    • (2012) Circulation , vol.125
    • Roger, V.L.1
  • 28
    • 84862059081 scopus 로고    scopus 로고
    • A scalable system for production of functional pancreatic progenitors from human embryonic stem cells
    • Schulz, T. C., et al. A scalable system for production of functional pancreatic progenitors from human embryonic stem cells. PLoS One 7:e37004, 2012.
    • (2012) PLoS One , vol.7
    • Schulz, T.C.1
  • 29
    • 84861345298 scopus 로고    scopus 로고
    • Process engineering of human pluripotent stem cells for clinical application
    • Serra, M., C. Brito, C. Correia, and P. M. Alves. Process engineering of human pluripotent stem cells for clinical application. Trends Biotechnol. 30:350-358, 2012.
    • (2012) Trends Biotechnol. , vol.30 , pp. 350-358
    • Serra, M.1    Brito, C.2    Correia, C.3    Alves, P.M.4
  • 30
    • 79961158737 scopus 로고    scopus 로고
    • Microencapsulation technology: A powerful tool for integrating expansion and cryopreservation of human embryonic stem cells
    • Serra, M., et al. Microencapsulation technology: a powerful tool for integrating expansion and cryopreservation of human embryonic stem cells. PLoS One 6:e23212, 2011.
    • (2011) PLoS One , vol.6
    • Serra, M.1
  • 31
    • 77952429809 scopus 로고    scopus 로고
    • Up-scaling single cell-inoculated suspension culture of human embryonic stem cells
    • Singh, H., P. Mok, T. Balakrishnan, S. N. B. Rahmat, and R. Zweigerdt. Up-scaling single cell-inoculated suspension culture of human embryonic stem cells. Stem Cell Res. 4:165-179, 2010.
    • (2010) Stem Cell Res. , vol.4 , pp. 165-179
    • Singh, H.1    Mok, P.2    Balakrishnan, T.3    Rahmat, S.N.B.4    Zweigerdt, R.5
  • 32
    • 77950677122 scopus 로고    scopus 로고
    • Derivation, propagation and controlled differentiation of human embryonic stem cells in suspension
    • Steiner, D., et al. Derivation, propagation and controlled differentiation of human embryonic stem cells in suspension. Nat. Biotechnol. 28:361-364, 2010.
    • (2010) Nat. Biotechnol. , vol.28 , pp. 361-364
    • Steiner, D.1
  • 33
    • 79955913737 scopus 로고    scopus 로고
    • Sustained embryoid body formation and culture in a non-laborious three dimensional culture system for human embryonic stem cells
    • Stenberg, J., M. Elovsson, R. Strehl, E. Kilmare, J. Hyllner, and A. Lindahl. Sustained embryoid body formation and culture in a non-laborious three dimensional culture system for human embryonic stem cells. Cytotechnology 63:227-237, 2011.
    • (2011) Cytotechnology , vol.63 , pp. 227-237
    • Stenberg, J.1    Elovsson, M.2    Strehl, R.3    Kilmare, E.4    Hyllner, J.5    Lindahl, A.6
  • 34
    • 36248966518 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
    • DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
    • Takahashi, K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131:861-872, 2007. (Pubitemid 350138099)
    • (2007) Cell , vol.131 , Issue.5 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 35
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson, J. A. Embryonic stem cell lines derived from human blastocysts. Science 282:1145-1147, 1998. (Pubitemid 28516247)
    • (1998) Science , vol.282 , Issue.5391 , pp. 1145-1147
    • Thomson, J.A.1
  • 36
    • 48049106854 scopus 로고    scopus 로고
    • Good manufacturing practice and clinical-grade human embryonic stem cell lines
    • Unger, C., H. Skottman, P. Blomberg, M. S. Dilber, and O. Hovatta. Good manufacturing practice and clinical-grade human embryonic stem cell lines. Hum. Mol. Genet. 17:R48-R53, 2008.
    • (2008) Hum. Mol. Genet. , vol.17
    • Unger, C.1    Skottman, H.2    Blomberg, P.3    Dilber, M.S.4    Hovatta, O.5
  • 37
    • 27644486756 scopus 로고    scopus 로고
    • Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells
    • DOI 10.1242/jcs.02553
    • Vallier, L., M. Alexander, and R. A. Pedersen. Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells. J. Cell Sci. 118:4495-509, 2005. (Pubitemid 41556347)
    • (2005) Journal of Cell Science , vol.118 , Issue.19 , pp. 4495-4509
    • Vallier, L.1    Alexander, M.2    Pedersen, R.A.3
  • 38
    • 84871562830 scopus 로고    scopus 로고
    • The evolution of human pluripotent stem cell culture: From feeder cells to synthetic coatings
    • Villa-Diaz, L. G., A. M. Ross, J. Lahann, and P. H. Krebsbach. The evolution of human pluripotent stem cell culture: from feeder cells to synthetic coatings. Stem Cells 31:1-7, 2012.
    • (2012) Stem Cells , vol.31 , pp. 1-7
    • Villa-Diaz, L.G.1    Ross, A.M.2    Lahann, J.3    Krebsbach, P.H.4
  • 39
    • 48149098004 scopus 로고    scopus 로고
    • NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs
    • Xu, R.-H., et al. NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs. Cell Stem Cell 3:196-206, 2008.
    • (2008) Cell Stem Cell , vol.3 , pp. 196-206
    • Xu, R.-H.1
  • 40
    • 77952360137 scopus 로고    scopus 로고
    • Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules
    • Xu, Y., et al. Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc. Natl. Acad. Sci. U.S.A. 107:8129-8134, 2010.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 8129-8134
    • Xu, Y.1
  • 41
    • 84874105703 scopus 로고    scopus 로고
    • Cell-based assays in high-throughput screening for drug discovery
    • Zang, R., D. Li, I. Tang, J. Wang, and S. Yang. Cell-based assays in high-throughput screening for drug discovery. Int. J. Biotechnol. 1:31-51, 2012.
    • (2012) Int. J. Biotechnol. , vol.1 , pp. 31-51
    • Zang, R.1    Li, D.2    Tang, I.3    Wang, J.4    Yang, S.5
  • 42
    • 79955541641 scopus 로고    scopus 로고
    • Scalable expansion of human pluripotent stem cells in suspension culture
    • Zweigerdt, R., R. Olmer, H. Singh, A. Haverich, and U. Martin. Scalable expansion of human pluripotent stem cells in suspension culture. Nat. Protoc. 6:689-700, 2011.
    • (2011) Nat. Protoc. , vol.6 , pp. 689-700
    • Zweigerdt, R.1    Olmer, R.2    Singh, H.3    Haverich, A.4    Martin, U.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.