Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media

Vaccine

Volumn 24, Issue 35-36, 2006, Pages 6074-6087

  Genzel, Y ^a   Olmer, R M ^b   Schafer B ^a   Reichl, U ^a,c  

^a MAX PLANCK INSTITUTE FOR DYNAMICS OF COMPLEX TECHNICAL SYSTEMS   (Germany)

^b BIELEFELD UNIVERSITY   (Germany)

^c OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Amino acids; Equine influenza virus; MDCK; Microcarrier; Moi; Serum free; TCID50 stability; Time of infection; Vaccine production; Wave bioreactor

Indexed keywords

CALCIUM ION; EDETIC ACID; INFLUENZA VACCINE; TRYPSIN;

AMINO ACID METABOLISM; ANIMAL CELL; ARTICLE; BIOREACTOR; CARBON METABOLISM; CELL ADHESION; CELL DENSITY; CELL STRAIN; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CULTURE MEDIUM; INFECTION; INFLUENZA VIRUS; MICROCARRIER CULTURE; NONHUMAN; PH; PRIORITY JOURNAL; STIRRED REACTOR; VACCINE PRODUCTION; VIRUS INFECTION; VIRUS TITRATION;

AMINO ACIDS; AMMONIA; ANIMALS; BIOREACTORS; CELL COUNT; CELL CULTURE TECHNIQUES; CELL LINE; CULTURE MEDIA, SERUM-FREE; DOGS; GLUCOSE; HEMAGGLUTININS; HYDROGEN-ION CONCENTRATION; INFLUENZA A VIRUS, H3N8 SUBTYPE; LACTIC ACID; PYRUVIC ACID; TIME FACTORS;

EID: 33746809465     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2006.05.023     Document Type: Article

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