The hollow fiber bioreactor as a stroma-supported, serum-free ex vivo expansion platform for human umbilical cord blood cells

Biotechnology Journal

Volumn 9, Issue 7, 2014, Pages 980-989

  Xue, Cao ^a   Kwek, Kenneth Y C ^b   Chan, Jerry K Y ^b,c,d   Chen, Qingfeng ^e   Lim, Mayasari ^a  

^a Nanyang Technological University   (Singapore)

^b KK WOMEN'S AND CHILDREN'S HOSPITAL   (Singapore)

^c DUKE NUS MEDICAL SCHOOL   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

Bioreactors; Bone marrow mimetic; Continuous expansion system; Stroma contact

Indexed keywords

BIOCONVERSION; BIOREACTORS; BLOOD; BONE; CYTOLOGY; ENZYME INHIBITION; SCANNING ELECTRON MICROSCOPY; STEM CELLS; TISSUE CULTURE; TRANSMISSION CONTROL PROTOCOL;

BONE MARROW; BONE MARROW MICROENVIRONMENT; CONTINUOUS EXPANSION SYSTEM; EXTRACELLULAR MATRICES; HEMATOPOIETIC STEM CELLS; HOLLOW FIBER BIOREACTOR; HUMAN UMBILICAL CORD; TISSUE CULTURE POLYSTYRENES;

EXPANSION;

CD34 ANTIGEN; CD45 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 27; INTERLEUKIN 8;

ADHERENT CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CELL POPULATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; EX VIVO STUDY; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; GLUCOSE INTAKE; HEMATOPOIETIC STEM CELL; HOLLOW FIBER REACTOR; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SCANNING ELECTRON MICROSCOPY; STEM CELL EXPANSION; STROMA CELL; TISSUE CULTURE POLYSTYRENE; TISSUE CULTURE TECHNIQUE; UMBILICAL VEIN ENDOTHELIAL CELL; ANIMAL; BIOREACTOR; COCULTURE; CULTURE TECHNIQUE; CYTOLOGY; FETUS BLOOD; NONOBESE DIABETIC MOUSE; SCID MOUSE;

ANIMALS; BIOREACTORS; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; COCULTURE TECHNIQUES; FETAL BLOOD; HEMATOPOIETIC STEM CELLS; HUMANS; MICE; MICE, INBRED NOD; MICE, SCID; STROMAL CELLS;

EID: 84903782373     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201300320     Document Type: Article

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