Organs-on-a-chip: A new tool for drug discovery

Expert Opinion on Drug Discovery

Volumn 9, Issue 4, 2014, Pages 335-352

  Polini, Alessandro ^b,c   Prodanov, Ljupcho ^b,c   Bhise, Nupura S ^b,c   Manoharan, Vijayan ^b,c   Dokmeci, Mehmet R ^b,c   Khademhosseini, Ali ^a,d  

^a HARVARD UNIVERSITY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^d TOHOKU UNIVERSITY   (Japan)

Author keywords

Biomimicry; Body on a chip; Drug discovery platforms; in vitro models; in vitro reactors; Metabolic biomarkers; Microenvironment; Microfluidics; Organs on a chip; Sensors; Tissue engineering

Indexed keywords

BIOMEDICAL MICROELECTROMECHANICAL SYSTEM; BLOOD BRAIN BARRIER; BLOOD VESSEL; BLOOD VESSEL ON A CHIP; DRUG DEVELOPMENT; DRUG SCREENING; HEART; HEART ON A CHIP; HUMAN; LIVER; LIVER ON A CHIP; LUNG; LUNG ON A CHIP; MICROFLUIDICS; MICROTECHNOLOGY; MULTIPLE ORGANS ON A CHIP; NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; REVIEW; TUMOR ON A CHIP; ANIMAL; ANIMAL TESTING ALTERNATIVE; PROCEDURES; TISSUE CULTURE TECHNIQUE;

ANIMAL TESTING ALTERNATIVES; ANIMALS; BLOOD VESSELS; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; HEART; HUMANS; LIVER; LUNG; MICROFLUIDICS; TISSUE CULTURE TECHNIQUES;

EID: 84897017613     PISSN: 17460441     EISSN: 1746045X     Source Type: Journal    
DOI: 10.1517/17460441.2014.886562     Document Type: Review

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