Tau missorting and spastin-induced microtubule disruption in neurodegeneration: Alzheimer Disease and Hereditary Spastic Paraplegia

Molecular Neurodegeneration

Volumn 10, Issue 1, 2015, Pages

  Zempel, Hans ^a,c   Mandelkow, Eva Maria ^a,b,c  

^a GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^b CENTER OF ADVANCED EUROPEAN STUDIES AND RESEARCH CAESAR   (Germany)

^c DESY   (Germany)

Author keywords

Alzheimer disease; Amyloid beta; Cell polarity; Hereditary spastic paraplegia; Microtubule; Neurodegeneration; Spastin; Tau; TTLL6

Indexed keywords

LIGASE; OLIGOMER; PROTEIN INHIBITOR; SPASTIN; SPASTIN INHIBITOR; TAU PROTEIN; TUBULIN TYROSINE LIGASE LIKE 6; UNCLASSIFIED DRUG;

ALLELE; ALZHEIMER DISEASE; BRAIN MITOCHONDRION; CELL DISRUPTION; CELLULAR DISTRIBUTION; DENDRITE; GENE INACTIVATION; GENE MUTATION; GLIOBLASTOMA; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; MICROTUBULE; NERVE CELL LESION; NEUROPATHOLOGY; NONHUMAN; PROTEIN AGGREGATION; PROTEIN DEFECT; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN TARGETING; REVIEW; SPAST GENE; SYNAPSE; TAU GENE; TAUOPATHY; ANIMAL; METABOLISM; NERVE CELL;

ALZHEIMER DISEASE; ANIMALS; HUMANS; MICROTUBULES; NEURONS; SPASTIC PARAPLEGIA, HEREDITARY; SYNAPSES; TAU PROTEINS;

EID: 84954078732     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/s13024-015-0064-1     Document Type: Review

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