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Volumn 10, Issue 11, 2015, Pages

NRF2 Regulates PINK1 Expression under oxidative stress conditions

Author keywords

[No Author keywords available]

Indexed keywords

KELCH LIKE ECH ASSOCIATED PROTEIN 1; PHOSPHOTRANSFERASE; PTEN INDUCED PUTATIVE KINASE 1; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; MESSENGER RNA; NFE2L2 PROTEIN, HUMAN; PROTEIN KINASE; PTEN-INDUCED PUTATIVE KINASE;

EID: 84953253147     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0142438     Document Type: Article
Times cited : (152)

References (42)
  • 1
    • 2442668926 scopus 로고    scopus 로고
    • Hereditary early-onset Parkinson's disease caused by mutations in PINK1
    • Valente EM, Abou-Sleiman PM, Caputo V, Muqit MM, Harvey K, Gispert S, et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science. 2004; 304(5674):1158-60. doi: 10.1126/science.1096284 .
    • (2004) Science , vol.304 , Issue.5674 , pp. 1158-1160
    • Valente, E.M.1    Abou-Sleiman, P.M.2    Caputo, V.3    Muqit, M.M.4    Harvey, K.5    Gispert, S.6
  • 2
    • 22044432781 scopus 로고    scopus 로고
    • Early-onset parkinsonism associated with PINK1 mutations: Frequency, genotypes, and phenotypes
    • Bonifati V, Rohe CF, Breedveld GJ, Fabrizio E, De Mari M, Tassorelli C, et al. Early-onset parkinsonism associated with PINK1 mutations: frequency, genotypes, and phenotypes. Neurology. 2005; 65(1):87-95. doi: 10.1212/01.wnl.0000167546.39375.82 .
    • (2005) Neurology , vol.65 , Issue.1 , pp. 87-95
    • Bonifati, V.1    Rohe, C.F.2    Breedveld, G.J.3    Fabrizio, E.4    De Mari, M.5    Tassorelli, C.6
  • 3
    • 79953185407 scopus 로고    scopus 로고
    • A new cytosolic pathway from a Parkinson disease-Associated kinase, BRPK/PINK1: Activation of AKT via mTORC2
    • Murata H, Sakaguchi M, Jin Y, Sakaguchi Y, Futami J, Yamada H, et al. A new cytosolic pathway from a Parkinson disease-Associated kinase, BRPK/PINK1: Activation of AKT via mTORC2. J Biol Chem. 2011; 286(9):7182-9. doi: 10.1074/jbc.M110.179390.
    • (2011) J Biol Chem , vol.286 , Issue.9 , pp. 7182-7189
    • Murata, H.1    Sakaguchi, M.2    Jin, Y.3    Sakaguchi, Y.4    Futami, J.5    Yamada, H.6
  • 4
    • 84873028465 scopus 로고    scopus 로고
    • Tricornered/NDR kinase signaling mediates PINK1-directed mitochondrial quality control and tissue maintenance
    • Wu Z, Sawada T, Shiba K, Liu S, Kanao T, Takahashi R, et al. Tricornered/NDR kinase signaling mediates PINK1-directed mitochondrial quality control and tissue maintenance. Genes Dev. 2013; 27 (2):157-62. doi: 10.1101/gad.203406.112.
    • (2013) Genes Dev , vol.27 , Issue.2 , pp. 157-162
    • Wu, Z.1    Sawada, T.2    Shiba, K.3    Liu, S.4    Kanao, T.5    Takahashi, R.6
  • 5
    • 84856299100 scopus 로고    scopus 로고
    • Partial sensitization of human bladder cancer cells to a gene-Therapeutic adenovirus carrying REIC/Dkk-3 by downregulation of BRPK/PINK1
    • Jin Y, Murata H, Sakaguchi M, Kataoka K, Watanabe M, Nasu Y, et al. Partial sensitization of human bladder cancer cells to a gene-Therapeutic adenovirus carrying REIC/Dkk-3 by downregulation of BRPK/PINK1. Oncol Rep. 2012; 27(3):695-9. doi: 10.3892/or.2011.1543 .
    • (2012) Oncol Rep , vol.27 , Issue.3 , pp. 695-699
    • Jin, Y.1    Murata, H.2    Sakaguchi, M.3    Kataoka, K.4    Watanabe, M.5    Nasu, Y.6
  • 6
    • 84880303306 scopus 로고    scopus 로고
    • PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its proapoptotic cleavage
    • Arena G, Gelmetti V, Torosantucci L, Vignone D, Lamorte G, De Rosa P, et al. PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its proapoptotic cleavage. Cell Death Differ. 2013. http://www.nature.com/cdd/journal/vaop/ncurrent/suppinfo/cdd201319s1.html.
    • (2013) Cell Death Differ
    • Arena, G.1    Gelmetti, V.2    Torosantucci, L.3    Vignone, D.4    Lamorte, G.5    De Rosa, P.6
  • 7
    • 75749156257 scopus 로고    scopus 로고
    • PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
    • Narendra DP, Jin SM, Tanaka A, Suen DF, Gautier CA, Shen J, et al. PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol. 2010; 8(1):e1000298. doi: 10.1371/journal.pbio. 1000298.
    • (2011) PLoS Biol , vol.8 , Issue.1 , pp. e1000298
    • Narendra, D.P.1    Jin, S.M.2    Tanaka, A.3    Suen, D.F.4    Gautier, C.A.5    Shen, J.6
  • 8
    • 77951181836 scopus 로고    scopus 로고
    • PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
    • Matsuda N, Sato S, Shiba K, Okatsu K, Saisho K, Gautier CA, et al. PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J Cell Biol. 2010; 189(2):211-21. doi: 10.1083/jcb.200910140.
    • (2011) J Cell Biol , vol.189 , Issue.2 , pp. 211-221
    • Matsuda, N.1    Sato, S.2    Shiba, K.3    Okatsu, K.4    Saisho, K.5    Gautier, C.A.6
  • 9
    • 84884494185 scopus 로고    scopus 로고
    • SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria
    • Murata H, Sakaguchi M, Kataoka K, Huh NH. SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria. Mol Biol Cell. 2013; 24(18):2772-84. doi: 10.1091/mbc.E13-01-0016.
    • (2013) Mol Biol Cell , vol.24 , Issue.18 , pp. 2772-2784
    • Murata, H.1    Sakaguchi, M.2    Kataoka, K.3    Huh, N.H.4
  • 10
    • 58149314211 scopus 로고    scopus 로고
    • Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
    • Narendra D, Tanaka A, Suen DF, Youle RJ. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol. 2008; 183(5):795-803. doi: 10.1083/jcb.200809125.
    • (2008) J Cell Biol , vol.183 , Issue.5 , pp. 795-803
    • Narendra, D.1    Tanaka, A.2    Suen, D.F.3    Youle, R.J.4
  • 11
    • 65249108225 scopus 로고    scopus 로고
    • FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation
    • Mei Y, Zhang Y, Yamamoto K, Xie W, Mak TW, You H. FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation. Proc Natl Acad Sci U S A. 2009; 106 (13):5153-8. doi: 10.1073/pnas.0901104106.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.13 , pp. 5153-5158
    • Mei, Y.1    Zhang, Y.2    Yamamoto, K.3    Xie, W.4    Mak, T.W.5    You, H.6
  • 13
    • 84896707109 scopus 로고    scopus 로고
    • Oxidative stress and regulation of Pink1 in zebrafish (Danio rerio
    • Priyadarshini M, Orosco LA, Panula PJ. Oxidative stress and regulation of Pink1 in zebrafish (Danio rerio). PLoS One. 2013; 8(11):e81851. doi: 10.1371/journal.pone.0081851.
    • (2013) PLoS One , vol.8 , Issue.11 , pp. e81851
    • Priyadarshini, M.1    Orosco, L.A.2    Panula, P.J.3
  • 15
    • 0031577292 scopus 로고    scopus 로고
    • An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
    • Itoh K, Chiba T, Takahashi S, Ishii T, Igarashi K, Katoh Y, et al. An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun. 1997; 236(2):313-22. .
    • (1997) Biochem Biophys Res Commun , vol.236 , Issue.2 , pp. 313-322
    • Itoh, K.1    Chiba, T.2    Takahashi, S.3    Ishii, T.4    Igarashi, K.5    Katoh, Y.6
  • 16
    • 0035870298 scopus 로고    scopus 로고
    • The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes
    • McMahon M, Itoh K, Yamamoto M, Chanas SA, Henderson CJ, McLellan LI, et al. The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes. Cancer Res. 2001; 61(8):3299-307. .
    • (2001) Cancer Res , vol.61 , Issue.8 , pp. 3299-3307
    • McMahon, M.1    Itoh, K.2    Yamamoto, M.3    Chanas, S.A.4    Henderson, C.J.5    McLellan, L.I.6
  • 17
    • 0042330074 scopus 로고    scopus 로고
    • Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: Reassessment of the ARE consensus sequence
    • Nioi P, McMahon M, Itoh K, Yamamoto M, Hayes JD. Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H:quinone oxidoreductase 1 gene: reassessment of the ARE consensus sequence. Biochem J. 2003; 374(Pt 2):337-48. doi: 10.1042/BJ20030754.
    • (2003) Biochem J , vol.374 , pp. 337-348
    • Nioi, P.1    McMahon, M.2    Itoh, K.3    Yamamoto, M.4    Hayes, J.D.5
  • 18
    • 0033584867 scopus 로고    scopus 로고
    • Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2
    • Wild AC, Moinova HR, Mulcahy RT. Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2. J Biol Chem. 1999; 274(47):33627-36. .
    • (1999) J Biol Chem , vol.274 , Issue.47 , pp. 33627-33636
    • Wild, A.C.1    Moinova, H.R.2    Mulcahy, R.T.3
  • 19
    • 0033543566 scopus 로고    scopus 로고
    • Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene
    • Alam J, Stewart D, Touchard C, Boinapally S, Choi AM, Cook JL. Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene. J Biol Chem. 1999; 274(37):26071-8. .
    • (1999) J Biol Chem , vol.274 , Issue.37 , pp. 26071-26078
    • Alam, J.1    Stewart, D.2    Touchard, C.3    Boinapally, S.4    Choi, A.M.5    Cook, J.L.6
  • 20
    • 0035853157 scopus 로고    scopus 로고
    • Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
    • Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, et al. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc Natl Acad Sci U S A. 2001; 98(6):3410-5. doi: 10.1073/pnas.051618798.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.6 , pp. 3410-3415
    • Ramos-Gomez, M.1    Kwak, M.K.2    Dolan, P.M.3    Itoh, K.4    Yamamoto, M.5    Talalay, P.6
  • 22
    • 3042716482 scopus 로고    scopus 로고
    • Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia
    • Lee JM, Chan K, Kan YW, Johnson JA. Targeted disruption of Nrf2 causes regenerative immune-mediated hemolytic anemia. Proc Natl Acad Sci U S A. 2004; 101(26):9751-6. doi: 10.1073/pnas. 0403620101.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.26 , pp. 9751-9756
    • Lee, J.M.1    Chan, K.2    Kan, Y.W.3    Johnson, J.A.4
  • 23
    • 62449132771 scopus 로고    scopus 로고
    • Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte
    • Chen PC, Vargas MR, Pani AK, Smeyne RJ, Johnson DA, Kan YW, et al. Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte. Proc Natl Acad Sci U S A. 2009; 106(8):2933-8. doi: 10.1073/pnas.0813361106.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.8 , pp. 2933-2938
    • Chen, P.C.1    Vargas, M.R.2    Pani, A.K.3    Smeyne, R.J.4    Johnson, D.A.5    Kan, Y.W.6
  • 24
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-Terminal Neh2 domain
    • Itoh K, Wakabayashi N, Katoh Y, Ishii T, Igarashi K, Engel JD, et al. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-Terminal Neh2 domain. Genes Dev. 1999; 13(1):76-86.
    • (1999) Genes Dev , vol.13 , Issue.1 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    Igarashi, K.5    Engel, J.D.6
  • 25
    • 77949262414 scopus 로고    scopus 로고
    • Cysteine-based regulation of the CUL3 adaptor protein Keap1
    • Sekhar KR, Rachakonda G, Freeman ML. Cysteine-based regulation of the CUL3 adaptor protein Keap1. Toxicol Appl Pharmacol. 2010; 244(1):21-6. doi: 10.1016/j.taap.2009.06.016.
    • (2011) Toxicol Appl Pharmacol , vol.244 , Issue.1 , pp. 21-26
    • Sekhar, K.R.1    Rachakonda, G.2    Freeman, M.L.3
  • 26
    • 17644365438 scopus 로고    scopus 로고
    • Mutations in PTENinduced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability
    • Beilina A, Van Der Brug M, Ahmad R, Kesavapany S, Miller DW, Petsko GA, et al. Mutations in PTENinduced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability. Proc Natl Acad Sci U S A. 2005; 102(16):5703-8. doi: 10.1073/pnas.0500617102.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.16 , pp. 5703-5708
    • Beilina, A.1    Van Der Brug, M.2    Ahmad, R.3    Kesavapany, S.4    Miller, D.W.5    Petsko, G.A.6
  • 27
    • 0034752461 scopus 로고    scopus 로고
    • Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
    • Katoh Y, Itoh K, Yoshida E, Miyagishi M, Fukamizu A, Yamamoto M. Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription. Genes Cells. 2001; 6(10):857-68. .
    • (2001) Genes Cells , vol.6 , Issue.10 , pp. 857-868
    • Katoh, Y.1    Itoh, K.2    Yoshida, E.3    Miyagishi, M.4    Fukamizu, A.5    Yamamoto, M.6
  • 28
    • 13644268144 scopus 로고    scopus 로고
    • Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells
    • Li J, Johnson D, Calkins M, Wright L, Svendsen C, Johnson J. Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells. Toxicol Sci. 2005; 83 (2):313-28. doi: 10.1093/toxsci/kfi027 .
    • (2005) Toxicol Sci , vol.83 , Issue.2 , pp. 313-328
    • Li, J.1    Johnson, D.2    Calkins, M.3    Wright, L.4    Svendsen, C.5    Johnson, J.6
  • 29
    • 79955667485 scopus 로고    scopus 로고
    • The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
    • Meissner C, Lorenz H, Weihofen A, Selkoe DJ, Lemberg MK. The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. J Neurochem. 2011; 117(5):856-67. doi: 10.1111/j.1471-4159.2011.07253.x .
    • (2011) J Neurochem , vol.117 , Issue.5 , pp. 856-867
    • Meissner, C.1    Lorenz, H.2    Weihofen, A.3    Selkoe, D.J.4    Lemberg, M.K.5
  • 30
    • 0034522060 scopus 로고    scopus 로고
    • Chemoprotection by organosulfur inducers of phase 2 enzymes: Dithiolethiones and dithiins
    • Kensler TW, Curphey TJ, Maxiutenko Y, Roebuck BD. Chemoprotection by organosulfur inducers of phase 2 enzymes: dithiolethiones and dithiins. Drug Metabol Drug Interact. 2000; 17(1-4):3-22. .
    • (2000) Drug Metabol Drug Interact , vol.17 , Issue.1-4 , pp. 3-22
    • Kensler, T.W.1    Curphey, T.J.2    Maxiutenko, Y.3    Roebuck, B.D.4
  • 31
    • 56249104197 scopus 로고    scopus 로고
    • Phytochemicals as protectors against ultraviolet radiation: Versatility of effects and mechanisms
    • Dinkova-Kostova AT. Phytochemicals as protectors against ultraviolet radiation: versatility of effects and mechanisms. Planta Med. 2008; 74(13):1548-59. doi: 10.1055/s-2008-1081296 .
    • (2008) Planta Med , vol.74 , Issue.13 , pp. 1548-1559
    • Dinkova-Kostova, A.T.1
  • 32
    • 0037569694 scopus 로고    scopus 로고
    • Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
    • Balogun E, Hoque M, Gong P, Killeen E, Green CJ, Foresti R, et al. Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element. Biochem J. 2003; 371(Pt 3):887-95. doi: 10.1042/BJ20021619.
    • (2003) Biochem J , vol.371 , pp. 887-895
    • Balogun, E.1    Hoque, M.2    Gong, P.3    Killeen, E.4    Green, C.J.5    Foresti, R.6
  • 33
    • 78649320759 scopus 로고    scopus 로고
    • Tert-butylhydroquinone induces mitochondrial oxidative stress causing Nrf2 activation
    • Imhoff BR, Hansen JM. Tert-butylhydroquinone induces mitochondrial oxidative stress causing Nrf2 activation. Cell Biol Toxicol. 2010; 26(6):541-51. doi: 10.1007/s10565-010-9162-6 .
    • (2011) Cell Biol Toxicol , vol.26 , Issue.6 , pp. 541-551
    • Imhoff, B.R.1    Hansen, J.M.2
  • 34
    • 0242321145 scopus 로고    scopus 로고
    • BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential
    • Nakajima A, Kataoka K, Hong M, Sakaguchi M, Huh NH. BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential. Cancer Lett. 2003; 201(2):195-201. .
    • (2003) Cancer Lett , vol.201 , Issue.2 , pp. 195-201
    • Nakajima, A.1    Kataoka, K.2    Hong, M.3    Sakaguchi, M.4    Huh, N.H.5
  • 35
    • 79960060305 scopus 로고    scopus 로고
    • Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
    • DeNicola GM, Karreth FA, Humpton TJ, Gopinathan A, Wei C, Frese K, et al. Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis. Nature. 2011; 475(7354):106-9. doi: 10. 1038/nature10189.
    • (2011) Nature , vol.475 , Issue.7354 , pp. 106-109
    • DeNicola, G.M.1    Karreth, F.A.2    Humpton, T.J.3    Gopinathan, A.4    Wei, C.5    Frese, K.6
  • 36
    • 84885944468 scopus 로고    scopus 로고
    • The emerging role of the Nrf2-Keap1 signaling pathway in cancer
    • Jaramillo MC, Zhang DD. The emerging role of the Nrf2-Keap1 signaling pathway in cancer. Genes Dev. 2013; 27(20):2179-91. doi: 10.1101/gad.225680.113.
    • (2013) Genes Dev , vol.27 , Issue.20 , pp. 2179-2191
    • Jaramillo, M.C.1    Zhang, D.D.2
  • 37
    • 77649265091 scopus 로고    scopus 로고
    • The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
    • Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, et al. The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol. 2010; 12(3):213-23. doi: 10.1038/ncb2021 .
    • (2011) Nat Cell Biol , vol.12 , Issue.3 , pp. 213-223
    • Komatsu, M.1    Kurokawa, H.2    Waguri, S.3    Taguchi, K.4    Kobayashi, A.5    Ichimura, Y.6
  • 38
    • 0033538473 scopus 로고    scopus 로고
    • Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
    • Wu Z, Puigserver P, Andersson U, Zhang C, Adelmant G, Mootha V, et al. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell. 1999; 98 (1):115-24. doi: 10.1016/S0092-8674(00)80611-X .
    • (1999) Cell , vol.98 , Issue.1 , pp. 115-124
    • Wu, Z.1    Puigserver, P.2    Andersson, U.3    Zhang, C.4    Adelmant, G.5    Mootha, V.6
  • 39
    • 0033803048 scopus 로고    scopus 로고
    • Peroxisome proliferator-Activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis
    • Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP. Peroxisome proliferator-Activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest. 2000; 106(7):847-56. doi: 10.1172/JCI10268.
    • (2000) J Clin Invest , vol.106 , Issue.7 , pp. 847-856
    • Lehman, J.J.1    Barger, P.M.2    Kovacs, A.3    Saffitz, J.E.4    Medeiros, D.M.5    Kelly, D.P.6
  • 40
    • 84891699279 scopus 로고    scopus 로고
    • Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway
    • Lou H, Jing X, Wei X, Shi H, Ren D, Zhang X. Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway. Neuropharmacology. 2013; 79C:380-8. doi: 10. 1016/j.neuropharm.2013.11.026 .
    • (2013) Neuropharmacology , vol.79 , pp. 380-388
    • Lou, H.1    Jing, X.2    Wei, X.3    Shi, H.4    Ren, D.5    Zhang, X.6
  • 41
    • 84882707345 scopus 로고    scopus 로고
    • Phloroglucinol attenuates motor functional deficits in an animal model of Parkinson's disease by enhancing Nrf2 activity
    • Ryu J, Zhang R, Hong BH, Yang EJ, Kang KA, Choi M, et al. Phloroglucinol attenuates motor functional deficits in an animal model of Parkinson's disease by enhancing Nrf2 activity. PLoS One. 2013; 8(8): e71178. doi: 10.1371/journal.pone.0071178.
    • (2013) PLoS One , vol.8 , Issue.8 , pp. e71178
    • Ryu, J.1    Zhang, R.2    Hong, B.H.3    Yang, E.J.4    Kang, K.A.5    Choi, M.6
  • 42
    • 65849512212 scopus 로고    scopus 로고
    • Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures
    • Siebert A, Desai V, Chandrasekaran K, Fiskum G, Jafri MS. Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures. J Neurosci Res. 2009; 87(7):1659-69. doi: 10.1002/jnr.21975 .
    • (2009) J Neurosci Res , vol.87 , Issue.7 , pp. 1659-1669
    • Siebert, A.1    Desai, V.2    Chandrasekaran, K.3    Fiskum, G.4    Jafri, M.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.