Phloroglucinol Attenuates Motor Functional Deficits in an Animal Model of Parkinson's Disease by Enhancing Nrf2 Activity

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Ryu, Junghwa ^a   Zhang, Rui ^b   Hong, Bo Hyun ^a   Yang, Eun Jung ^a   Kang, Kyoung Ah ^b   Choi, Moonseok ^a   Kim, Ki Cheon ^b   Noh, Su Jin ^a   Kim, Hee Soo ^c   Lee, Nam Ho ^b   Hyun, Jin Won ^b   Kim, Hye Sun ^a,d  

^a Seoul National University   (South Korea)

^b Jeju National University   (South Korea)

^c Konkuk University   (South Korea)

^d Seoul National University Bundang Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CATALASE; GLUTATHIONE PEROXIDASE; PHLOROGLUCINOL; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR NRF2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN REGION; CELL DAMAGE; CELL LOSS; CELL VIABILITY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; ENZYME ACTIVITY; IMMUNOREACTIVITY; LIPID PEROXIDATION; MALE; MESENCEPHALON; MOTOR ACTIVITY; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PROTEIN EXPRESSION; RAT; ROTAROD TEST; SUBSTANTIA NIGRA; SYNAPSE; UPREGULATION;

ANIMALS; ANTIPARKINSON AGENTS; CATALASE; CELL LINE; GENE EXPRESSION; GLUTATHIONE PEROXIDASE; GUANINE; LIPID PEROXIDATION; MALE; MESENCEPHALON; MOTOR ACTIVITY; NEURONS; NF-E2-RELATED FACTOR 2; OXIDOPAMINE; PARKINSON DISEASE, SECONDARY; PHLOROGLUCINOL; PROTEIN CARBONYLATION; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SYNAPSES; SYNAPTOPHYSIN;

EID: 84882707345     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071178     Document Type: Article

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