Amyloid Fibres: Inert End-Stage Aggregates or Key Players in Disease?

Trends in Biochemical Sciences

Volumn 40, Issue 12, 2015, Pages 719-727

  Tipping, Kevin W ^a   van Oosten Hawle, Patricija ^a   Hewitt, Eric W ^a   Radford, Sheena E ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Amyloid; Disease; Fibres; Transmission

Indexed keywords

ALPHA SYNUCLEIN; AMYLOID; AMYLOID BETA PROTEIN[1-40]; AMYLOID PRECURSOR PROTEIN; BETA 2 MICROGLOBULIN; LYSOZYME; MONOMER; OLIGOMER;

AMYLOIDOSIS; CELL DEGENERATION; COMPLEX FORMATION; CYTOTOXICITY; DISEASE COURSE; END STAGE AGGREGATE; FIBER FRAGMENTATION; FIBER INCUDED TOXICITY; GENERAL ASPECTS OF DISEASE; HISTORY OF MEDICINE; HUMAN; INCUBATION TIME; LYSOSOME; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; PROTEIN MISFOLDING; REVIEW; SECONDARY NUCLEATION; THERMODYNAMICS; THERMOSTABILITY; TOXICITY; ALZHEIMER DISEASE; ANIMAL; CHEMISTRY; METABOLISM; PROTEINOSIS; PROTEOSTASIS DEFICIENCIES;

ALZHEIMER DISEASE; AMYLOID; ANIMALS; HUMANS; PROTEIN AGGREGATION, PATHOLOGICAL; PROTEOSTASIS DEFICIENCIES;

EID: 84953239802     PISSN: 09680004     EISSN: 13624326     Source Type: Journal    
DOI: 10.1016/j.tibs.2015.10.002     Document Type: Review

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