Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain

Nature Communications

Volumn 6, Issue , 2015, Pages

  Pearce, Margaret M P ^a   Spartz, Ellen J ^a   Hong, Weizhe ^a,b   Luo, Liqun ^a   Kopito, Ron R ^a  

^a STANFORD UNIVERSITY   (United States)

^b California Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUNTINGTIN; PROTEIN AGGREGATE; SCAVENGER RECEPTOR; BACTERIAL PROTEIN; DRAPER PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; HUNTINGTIN PROTEIN, DROSOPHILA; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; PHOTOPROTEIN; PRION; RED FLUORESCENT PROTEIN; YELLOW FLUORESCENT PROTEIN, BACTERIA;

AGGREGATE; BRAIN; CYTOPLASM; DISABILITY; FLY; MUTATION; NEUROLOGY; PROTEIN; SCAVENGING (CHEMISTRY); SIGNALING;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL BODY; CELL INCLUSION; CONTROLLED STUDY; CYTOPLASM; FRUIT FLY MODEL; GLIA CELL; HUNTINGTON CHOREA; NONHUMAN; PHAGOCYTE; PHAGOCYTOSIS; PRION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; BRAIN; CHEMISTRY; DISEASE COURSE; DISEASE MODEL; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; GENETICS; GLIA; HUMAN; METABOLISM; MOLECULAR MIMICRY; MUTATION; NERVE CELL; PATHOLOGY; PROTEINOSIS; REPORTER GENE;

ANIMALS; BACTERIAL PROTEINS; BRAIN; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; HUNTINGTON DISEASE; LUMINESCENT PROTEINS; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MOLECULAR MIMICRY; MUTATION; NEUROGLIA; NEURONS; PHAGOCYTOSIS; PRIONS; PROTEIN AGGREGATES; PROTEIN AGGREGATION, PATHOLOGICAL; SIGNAL TRANSDUCTION;

EID: 84927949614     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7768     Document Type: Article

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