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Volumn 6, Issue , 2016, Pages

Telomerase reverse transcriptase acts in a feedback loop with NF-? B pathway to regulate macrophage polarization in alcoholic liver disease

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; TELOMERASE;

EID: 84952925002     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep18685     Document Type: Article
Times cited : (51)

References (58)
  • 1
    • 80054872790 scopus 로고    scopus 로고
    • Alcoholic liver disease: Pathogenesis and new therapeutic targets
    • Gao, B. & Bataller, R. Alcoholic liver disease: pathogenesis and new therapeutic targets. Gastroenterology 141, 1572-1585 (2011).
    • (2011) Gastroenterology , vol.141 , pp. 1572-1585
    • Gao, B.1    Bataller, R.2
  • 2
    • 67649116613 scopus 로고    scopus 로고
    • Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders
    • Rehm, J. et al. Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders. Lancet 373, 2223-2233 (2009).
    • (2009) Lancet , vol.373 , pp. 2223-2233
    • Rehm, J.1
  • 3
    • 84945304661 scopus 로고    scopus 로고
    • Trends in the management and burden of alcoholic liver disease
    • Mathurin, P. & Bataller, R. Trends in the management and burden of alcoholic liver disease. J Hepatol 62, S38-S46 (2015).
    • (2015) J Hepatol , vol.62 , pp. S38-S46
    • Mathurin, P.1    Bataller, R.2
  • 4
    • 84922868050 scopus 로고    scopus 로고
    • Gut-liver axis in alcoholic liver disease
    • Szabo, G. Gut-liver axis in alcoholic liver disease. Gastroenterology 148, 30-36 (2015).
    • (2015) Gastroenterology , vol.148 , pp. 30-36
    • Szabo, G.1
  • 5
    • 84926420371 scopus 로고    scopus 로고
    • Alcoholic liver disease: Mechanisms of injury and targeted treatment
    • Louvet, A. & Mathurin, P. Alcoholic liver disease: mechanisms of injury and targeted treatment. Nat Rev Gastroenterol Hepatol 12, 231-242 (2015).
    • (2015) Nat Rev Gastroenterol Hepatol , vol.12 , pp. 231-242
    • Louvet, A.1    Mathurin, P.2
  • 6
    • 33644527617 scopus 로고    scopus 로고
    • Alcohol and oxidative liver injury
    • Dey, A. & Cederbaum, A. I. Alcohol and oxidative liver injury. Hepatology 43, S63-74 (2006).
    • (2006) Hepatology , vol.43 , pp. S63-74
    • Dey, A.1    Cederbaum, A.I.2
  • 7
    • 3142759942 scopus 로고    scopus 로고
    • Molecular aspects of alcohol metabolism: Transcription factors involved in early ethanol-induced liver injury
    • Nagy, L. E. Molecular aspects of alcohol metabolism: Transcription factors involved in early ethanol-induced liver injury. Annu Rev Nutr 24, 55-78 (2004).
    • (2004) Annu Rev Nutr , vol.24 , pp. 55-78
    • Nagy, L.E.1
  • 8
    • 84864216017 scopus 로고    scopus 로고
    • Inflammation in alcoholic liver disease
    • Wang, H. J., Gao, B., Zakhari, S. & Nagy, L. E. Inflammation in alcoholic liver disease. Annu Rev Nutr 32, 343-368 (2012).
    • (2012) Annu Rev Nutr , vol.32 , pp. 343-368
    • Wang, H.J.1    Gao, B.2    Zakhari, S.3    Nagy, L.E.4
  • 9
    • 84866097840 scopus 로고    scopus 로고
    • Cytokines in alcoholic liver disease
    • An, L., Wang, X. & Cederbaum, A. I. Cytokines in alcoholic liver disease. Arch Toxicol 86, 1337-1348 (2012).
    • (2012) Arch Toxicol , vol.86 , pp. 1337-1348
    • An, L.1    Wang, X.2    Cederbaum, A.I.3
  • 10
    • 0034108596 scopus 로고    scopus 로고
    • Role of Kupffer cells and gut-derived endotoxins in alcoholic liver injury
    • Enomoto, N. et al. Role of Kupffer cells and gut-derived endotoxins in alcoholic liver injury. J Gastroenterol Hepatol 15 Suppl, D20-25 (2000).
    • (2000) J Gastroenterol Hepatol , vol.15 , pp. D20-25
    • Enomoto, N.1
  • 12
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser, D. M. & Edwards, J. P. Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8, 958-969 (2008).
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 14
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon, S. Alternative activation of macrophages. Nat Rev Immunol 3, 23-35 (2003).
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 15
    • 77953268611 scopus 로고    scopus 로고
    • Alternative activation of macrophages: Mechanism and functions
    • Gordon, S. & Martinez, F. O. Alternative activation of macrophages: mechanism and functions. Immunity 32, 593-604 (2010).
    • (2011) Immunity , vol.32 , pp. 593-604
    • Gordon, S.1    Martinez, F.O.2
  • 16
    • 84879103109 scopus 로고    scopus 로고
    • Macrophage activation and polarization as an adaptive component of innate immunity
    • Locati, M., Mantovani, A. & Sica, A. Macrophage activation and polarization as an adaptive component of innate immunity. Adv Immunol 120, 163-184 (2013).
    • (2013) Adv Immunol , vol.120 , pp. 163-184
    • Locati, M.1    Mantovani, A.2    Sica, A.3
  • 17
    • 84904394690 scopus 로고    scopus 로고
    • Macrophage activation and polarization: Nomenclature and experimental guidelines
    • Murray, P. J. et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity 41, 14-20 (2014).
    • (2014) Immunity , vol.41 , pp. 14-20
    • Murray, P.J.1
  • 18
    • 84876800337 scopus 로고    scopus 로고
    • Macrophage biology in development, homeostasis and disease
    • Wynn, T. A., Chawla, A. & Pollard, J. W. Macrophage biology in development, homeostasis and disease. Nature 496, 445-455 (2013).
    • (2013) Nature , vol.496 , pp. 445-455
    • Wynn, T.A.1    Chawla, A.2    Pollard, J.W.3
  • 19
    • 80355131976 scopus 로고    scopus 로고
    • Protective and pathogenic functions of macrophage subsets
    • Murray, P. J. & Wynn, T. A. Protective and pathogenic functions of macrophage subsets. Nat Rev Immunol 11, 723-737 (2011).
    • (2011) Nat Rev Immunol , vol.11 , pp. 723-737
    • Murray, P.J.1    Wynn, T.A.2
  • 20
    • 84933177312 scopus 로고    scopus 로고
    • Liver inflammation abrogates immunological tolerance induced by Kupffer cells
    • Heymann, F. et al. Liver inflammation abrogates immunological tolerance induced by Kupffer cells. Hepatology 62, 279-291 (2015).
    • (2015) Hepatology , vol.62 , pp. 279-291
    • Heymann, F.1
  • 21
    • 84860121459 scopus 로고    scopus 로고
    • Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy
    • Marchetti, V. et al. Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy. Sci Rep 1, 76 (2011).
    • (2011) Sci Rep , vol.1 , pp. 76
    • Marchetti, V.1
  • 22
    • 84901020809 scopus 로고    scopus 로고
    • M2 kupffer cells promote hepatocyte senescence: An IL-6-dependent protective mechanism against alcoholic liver disease
    • Wan, J., Benkdane, M., Alons, E., Lotersztajn, S. & Pavoine, C. M2 kupffer cells promote hepatocyte senescence: An IL-6-dependent protective mechanism against alcoholic liver disease. Am J Pathol 184, 1763-1772 (2014).
    • (2014) Am J Pathol , vol.184 , pp. 1763-1772
    • Wan, J.1    Benkdane, M.2    Alons, E.3    Lotersztajn, S.4    Pavoine, C.5
  • 23
    • 84894798789 scopus 로고    scopus 로고
    • M2 Kupffer cells promote M1 Kupffer cell apoptosis: A protective mechanism against alcoholic and nonalcoholic fatty liver disease
    • Wan, J. et al. M2 Kupffer cells promote M1 Kupffer cell apoptosis: A protective mechanism against alcoholic and nonalcoholic fatty liver disease. Hepatology 59, 130-142 (2014).
    • (2014) Hepatology , vol.59 , pp. 130-142
    • Wan, J.1
  • 25
    • 84932184510 scopus 로고    scopus 로고
    • Human telomerase: Biogenesis, trafficking, recruitment, and activation
    • Schmidt, J. C. & Cech, T. R. Human telomerase: biogenesis, trafficking, recruitment, and activation. Genes Dev 29, 1095-1105 (2015).
    • (2015) Genes Dev , vol.29 , pp. 1095-1105
    • Schmidt, J.C.1    Cech, T.R.2
  • 27
    • 84902797424 scopus 로고    scopus 로고
    • Transcriptional outcome of telomere signalling
    • Ye, J., Renault, V. M., Jamet, K. & Gilson, E. Transcriptional outcome of telomere signalling. Nat Rev Genet 15, 491-503 (2014).
    • (2014) Nat Rev Genet , vol.15 , pp. 491-503
    • Ye, J.1    Renault, V.M.2    Jamet, K.3    Gilson, E.4
  • 28
    • 4344683923 scopus 로고    scopus 로고
    • Telomeres and telomerase: New targets for the treatment of liver cirrhosis and hepatocellular carcinoma
    • Lechel, A., Manns, M. P. & Rudolph, K. L. Telomeres and telomerase: new targets for the treatment of liver cirrhosis and hepatocellular carcinoma. J Hepatol 41, 491-497 (2004).
    • (2004) J Hepatol , vol.41 , pp. 491-497
    • Lechel, A.1    Manns, M.P.2    Rudolph, K.L.3
  • 29
    • 79551486264 scopus 로고    scopus 로고
    • Telomerase activation in atherosclerosis and induction of telomerase reverse transcriptase expression by inflammatory stimuli in macrophages
    • Gizard, F. et al. Telomerase activation in atherosclerosis and induction of telomerase reverse transcriptase expression by inflammatory stimuli in macrophages. Arterioscler Thromb Vasc Biol 31, 245-252 (2011).
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 245-252
    • Gizard, F.1
  • 30
    • 84934439382 scopus 로고    scopus 로고
    • Human monocytes, macrophages, and dendritic cells: Alcohol treatment methods
    • Szabo, G. & Mandrekar, P. Human monocytes, macrophages, and dendritic cells: Alcohol treatment methods. Methods Mol Biol 447, 113-124 (2008).
    • (2008) Methods Mol Biol , vol.447 , pp. 113-124
    • Szabo, G.1    Mandrekar, P.2
  • 31
    • 80051987703 scopus 로고    scopus 로고
    • Crosstalk in NF-kappaB signaling pathways
    • Oeckinghaus, A., Hayden, M. S. & Ghosh, S. Crosstalk in NF-kappaB signaling pathways. Nat Immunol 12, 695-708 (2011).
    • (2011) Nat Immunol , vol.12 , pp. 695-708
    • Oeckinghaus, A.1    Hayden, M.S.2    Ghosh, S.3
  • 32
    • 84873695281 scopus 로고    scopus 로고
    • NF-kappaB: Roles and regulation in different CD4(+ ) T-cell subsets
    • Oh, H. & Ghosh, S. NF-kappaB: roles and regulation in different CD4(+ ) T-cell subsets. Immunol Rev 252, 41-51 (2013).
    • (2013) Immunol Rev , vol.252 , pp. 41-51
    • Oh, H.1    Ghosh, S.2
  • 33
    • 0034711223 scopus 로고    scopus 로고
    • NF-kappa B regulates transcription of the mouse telomerase catalytic subunit
    • Yin, L., Hubbard, A. K. & Giardina, C. NF-kappa B regulates transcription of the mouse telomerase catalytic subunit. J Biol Chem 275, 36671-36675 (2000).
    • (2000) J Biol Chem , vol.275 , pp. 36671-36675
    • Yin, L.1    Hubbard, A.K.2    Giardina, C.3
  • 34
    • 0035154623 scopus 로고    scopus 로고
    • PCR and in situ hybridization studies of telomerase subunits in human non-neoplastic livers
    • Harada, K., Yasoshima, M., Ozaki, S., Sanzen, T. & Nakanuma, Y. PCR and in situ hybridization studies of telomerase subunits in human non-neoplastic livers. J Pathol 193, 210-217 (2001).
    • (2001) J Pathol , vol.193 , pp. 210-217
    • Harada, K.1    Yasoshima, M.2    Ozaki, S.3    Sanzen, T.4    Nakanuma, Y.5
  • 35
    • 84907552775 scopus 로고    scopus 로고
    • Chronic alcohol ingestion modulates hepatic macrophage populations and functions in mice
    • Wang, M. et al. Chronic alcohol ingestion modulates hepatic macrophage populations and functions in mice. J Leukoc Biol 96, 657-665 (2014).
    • (2014) J Leukoc Biol , vol.96 , pp. 657-665
    • Wang, M.1
  • 37
    • 84893839302 scopus 로고    scopus 로고
    • The liver is populated by a broad spectrum of markers for macrophages. in alcoholic hepatitis the macrophages are M1 and M2
    • Lee, J., French, B., Morgan, T. & French, S. W. The liver is populated by a broad spectrum of markers for macrophages. In alcoholic hepatitis the macrophages are M1 and M2. Exp Mol Pathol 96, 118-125 (2014).
    • (2014) Exp Mol Pathol , vol.96 , pp. 118-125
    • Lee, J.1    French, B.2    Morgan, T.3    French, S.W.4
  • 38
    • 84929224130 scopus 로고    scopus 로고
    • Kruppel-like factor 4 is a transcriptional regulator of M1/M2 macrophage polarization in alcoholic liver disease
    • Saha, B., Bala, S., Hosseini, N., Kodys, K. & Szabo, G. Kruppel-like factor 4 is a transcriptional regulator of M1/M2 macrophage polarization in alcoholic liver disease. J Leukoc Biol 97, 963-973 (2015).
    • (2015) J Leukoc Biol , vol.97 , pp. 963-973
    • Saha, B.1    Bala, S.2    Hosseini, N.3    Kodys, K.4    Szabo, G.5
  • 39
    • 79952017845 scopus 로고    scopus 로고
    • Telomeric and extra-Telomeric roles for telomerase and the telomere-binding proteins
    • Martinez, P. & Blasco, M. A. Telomeric and extra-Telomeric roles for telomerase and the telomere-binding proteins. Nat Rev Cancer 11, 161-176 (2011).
    • (2011) Nat Rev Cancer , vol.11 , pp. 161-176
    • Martinez, P.1    Blasco, M.A.2
  • 40
    • 84896541314 scopus 로고    scopus 로고
    • Noncanonical functions of telomerase: Implications in telomerase-Targeted cancer therapies
    • Li, Y. & Tergaonkar, V. Noncanonical functions of telomerase: implications in telomerase-Targeted cancer therapies. Cancer Res 74, 1639-1644 (2014).
    • (2014) Cancer Res , vol.74 , pp. 1639-1644
    • Li, Y.1    Tergaonkar, V.2
  • 41
    • 84879108078 scopus 로고    scopus 로고
    • Transcriptional control of macrophage polarization
    • Tugal, D., Liao, X. & Jain, M. K. Transcriptional control of macrophage polarization. Arterioscler Thromb Vasc Biol 33, 1135-1144 (2013).
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 1135-1144
    • Tugal, D.1    Liao, X.2    Jain, M.K.3
  • 42
    • 67349255858 scopus 로고    scopus 로고
    • Signalling pathways in alcohol-induced liver inflammation
    • Mandrekar, P. & Szabo, G. Signalling pathways in alcohol-induced liver inflammation. J Hepatol 50, 1258-1266 (2009).
    • (2009) J Hepatol , vol.50 , pp. 1258-1266
    • Mandrekar, P.1    Szabo, G.2
  • 43
    • 0024316023 scopus 로고
    • Identification of a lipid A binding site in the acute phase reactant lipopolysaccharide binding protein
    • Tobias, P. S., Soldau, K. & Ulevitch, R. J. Identification of a lipid A binding site in the acute phase reactant lipopolysaccharide binding protein. J Biol Chem 264, 10867-10871 (1989).
    • (1989) J Biol Chem , vol.264 , pp. 10867-10871
    • Tobias, P.S.1    Soldau, K.2    Ulevitch, R.J.3
  • 44
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
    • Poltorak, A. et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282, 2085-2088 (1998).
    • (1998) Science , vol.282 , pp. 2085-2088
    • Poltorak, A.1
  • 45
    • 84856641109 scopus 로고    scopus 로고
    • NF-kappaB, the first quarter-century: Remarkable progress and outstanding questions
    • Hayden, M. S. & Ghosh, S. NF-kappaB, the first quarter-century: remarkable progress and outstanding questions. Genes Dev 26, 203-234 (2012).
    • (2012) Genes Dev , vol.26 , pp. 203-234
    • Hayden, M.S.1    Ghosh, S.2
  • 46
    • 84895521826 scopus 로고    scopus 로고
    • Regulation of the NF-kappaB-mediated transcription of inflammatory genes
    • Bhatt, D. & Ghosh, S. Regulation of the NF-kappaB-Mediated Transcription of Inflammatory Genes. Front Immunol 5, 71 (2014).
    • (2014) Front Immunol , vol.5 , pp. 71
    • Bhatt, D.1    Ghosh, S.2
  • 47
    • 67649668789 scopus 로고    scopus 로고
    • Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint
    • Huang, W., Ghisletti, S., Perissi, V., Rosenfeld, M. G. & Glass, C. K. Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint. Mol Cell 35, 48-57 (2009).
    • (2009) Mol Cell , vol.35 , pp. 48-57
    • Huang, W.1    Ghisletti, S.2    Perissi, V.3    Rosenfeld, M.G.4    Glass, C.K.5
  • 48
    • 78650878363 scopus 로고    scopus 로고
    • NF-kappaB, inflammation, and metabolic disease
    • Baker, R. G., Hayden, M. S. & Ghosh, S. NF-kappaB, inflammation, and metabolic disease. Cell Metab 13, 11-22 (2011).
    • (2011) Cell Metab , vol.13 , pp. 11-22
    • Baker, R.G.1    Hayden, M.S.2    Ghosh, S.3
  • 49
    • 23944526322 scopus 로고    scopus 로고
    • Global gene expression response to telomerase in bovine adrenocortical cells
    • Perrault, S. D., Hornsby, P. J. & Betts, D. H. Global gene expression response to telomerase in bovine adrenocortical cells. Biochem Biophys Res Commun 335, 925-936 (2005).
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 925-936
    • Perrault, S.D.1    Hornsby, P.J.2    Betts, D.H.3
  • 50
    • 84870616090 scopus 로고    scopus 로고
    • Telomerase directly regulates NF-kappaB-dependent transcription
    • Ghosh, A. et al. Telomerase directly regulates NF-kappaB-dependent transcription. Nat Cell Biol 14, 1270-1281 (2012).
    • (2012) Nat Cell Biol , vol.14 , pp. 1270-1281
    • Ghosh, A.1
  • 51
    • 84895544733 scopus 로고    scopus 로고
    • Telomere dysfunction in peripheral blood mononuclear cells from patients with primary biliary cirrhosis
    • Invernizzi, P. et al. Telomere dysfunction in peripheral blood mononuclear cells from patients with primary biliary cirrhosis. Dig Liver Dis 46, 363-368 (2014).
    • (2014) Dig Liver Dis , vol.46 , pp. 363-368
    • Invernizzi, P.1
  • 52
    • 84884167082 scopus 로고    scopus 로고
    • Feedback regulation of telomerase reverse transcriptase: New insight into the evolving field of telomerase in cancer
    • Wu, X. Q. et al. Feedback regulation of telomerase reverse transcriptase: new insight into the evolving field of telomerase in cancer. Cell Signal 25, 2462-2468 (2013).
    • (2013) Cell Signal , vol.25 , pp. 2462-2468
    • Wu, X.Q.1
  • 53
    • 84857692141 scopus 로고    scopus 로고
    • Differential macrophage programming in the tumor microenvironment
    • Ruffell, B., Affara, N. I. & Coussens, L. M. Differential macrophage programming in the tumor microenvironment. Trends Immunol 33, 119-126 (2012).
    • (2012) Trends Immunol , vol.33 , pp. 119-126
    • Ruffell, B.1    Affara, N.I.2    Coussens, L.M.3
  • 54
    • 84862617605 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling regulates telomerase in stem cells and cancer cells
    • Hoffmeyer, K. et al. Wnt/beta-catenin signaling regulates telomerase in stem cells and cancer cells. Science 336, 1549-1554 (2012).
    • (2012) Science , vol.336 , pp. 1549-1554
    • Hoffmeyer, K.1
  • 55
    • 79960021457 scopus 로고    scopus 로고
    • Kruppel-like factor 4 regulates macrophage polarization
    • Liao, X. et al. Kruppel-like factor 4 regulates macrophage polarization. J Clin Invest 121, 2736-2749 (2011).
    • (2011) J Clin Invest , vol.121 , pp. 2736-2749
    • Liao, X.1
  • 56
    • 84875160269 scopus 로고    scopus 로고
    • Mouse model of chronic and binge ethanol feeding (the NIAAA model)
    • Bertola, A., Mathews, S., Ki, S. H., Wang, H. & Gao, B. Mouse model of chronic and binge ethanol feeding (the NIAAA model). Nat Protoc 8 627-637 (2013).
    • (2013) Nat Protoc , vol.8 , pp. 627-637
    • Bertola, A.1    Mathews, S.2    Ki, S.H.3    Wang, H.4    Gao, B.5
  • 57
    • 0022416353 scopus 로고
    • Preparation of pure hepatocytes and reticuloendothelial cells in high yield from a single rat liver by means of Percoll centrifugation and selective adherence
    • Smedsrod, B. & Pertoft, H. Preparation of pure hepatocytes and reticuloendothelial cells in high yield from a single rat liver by means of Percoll centrifugation and selective adherence. J Leukoc Biol 38, 213-230 (1985).
    • (1985) J Leukoc Biol , vol.38 , pp. 213-230
    • Smedsrod, B.1    Pertoft, H.2
  • 58
    • 0036853729 scopus 로고    scopus 로고
    • The physiological scavenger receptor function of hepatic sinusoidal endothelial and Kupffer cells is independent of scavenger receptor class A type i and II
    • Hansen, B., Arteta, B. & Smedsrod, B. The physiological scavenger receptor function of hepatic sinusoidal endothelial and Kupffer cells is independent of scavenger receptor class A type I and II. Mol Cell Biochem 240, 1-8 (2002).
    • (2002) Mol Cell Biochem , vol.240 , pp. 1-8
    • Hansen, B.1    Arteta, B.2    Smedsrod, B.3


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