메뉴 건너뛰기




Volumn 5, Issue FEB, 2014, Pages

Regulation of the NF-κB-mediated transcription of inflammatory genes

Author keywords

Chromatin; Gene expression; NF kappaB; Signaling; Transcription; Transcription factor

Indexed keywords

BETA INTERFERON; DNA DIRECTED DNA POLYMERASE ALPHA; E1A ASSOCIATED P300 PROTEIN; GENERAL TRANSCRIPTION FACTOR; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; HISTONE DEACETYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; MEDIATOR COMPLEX; NUCLEAR RECEPTOR COREPRESSOR; PROTEASOME; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; STRESS ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR IIH;

EID: 84895521826     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00071     Document Type: Review
Times cited : (198)

References (79)
  • 1
    • 33645312379 scopus 로고    scopus 로고
    • Circuitry of nuclear factor kappaB signaling
    • doi:10.1111/j.0105-2896.2006.00375.x
    • Hoffmann A, Baltimore D. Circuitry of nuclear factor kappaB signaling. Immunol Rev (2006) 210:171-86. doi:10.1111/j.0105-2896.2006.00375.x.
    • (2006) Immunol Rev , vol.210 , pp. 171-186
    • Hoffmann, A.1    Baltimore, D.2
  • 2
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • doi:10.1016/j.cell.2008.01.020
    • Hayden MS, Ghosh S. Shared principles in NF-kappaB signaling. Cell (2008) 132:344-62. doi:10.1016/j.cell.2008.01.020.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 4
    • 70350491412 scopus 로고    scopus 로고
    • How eukaryotic genes are transcribed
    • doi:10.1080/10409230902858785
    • Venters BJ, Pugh BF. How eukaryotic genes are transcribed. Crit Rev Biochem Mol Biol (2009) 44:117-41. doi:10.1080/10409230902858785.
    • (2009) Crit Rev Biochem Mol Biol , vol.44 , pp. 117-141
    • Venters, B.J.1    Pugh, B.F.2
  • 5
    • 77958111633 scopus 로고    scopus 로고
    • The metazoan mediator co-activator complex as an integrative hub for transcriptional regulation
    • doi:10.1038/nrg2901
    • Malik S, Roeder RG. The metazoan mediator co-activator complex as an integrative hub for transcriptional regulation. Nat Rev Genet (2010) 11:761-72. doi:10.1038/nrg2901.
    • (2010) Nat Rev Genet , vol.11 , pp. 761-772
    • Malik, S.1    Roeder, R.G.2
  • 6
    • 34249063835 scopus 로고    scopus 로고
    • Dynamic usage of transcription start sites within core promoters
    • doi:10.1186/gb-2006-7-12-r118
    • Kawaji H, Frith MC, Katayama S, Sandelin A, Kai C, Kawai J, et al. Dynamic usage of transcription start sites within core promoters. Genome Biol (2006) 7:R118. doi:10.1186/gb-2006-7-12-r118.
    • (2006) Genome Biol , vol.7
    • Kawaji, H.1    Frith, M.C.2    Katayama, S.3    Sandelin, A.4    Kai, C.5    Kawai, J.6
  • 7
    • 44649193565 scopus 로고    scopus 로고
    • The RNA polymerase II core promoter-the gateway to transcription
    • doi:10.1016/j.ceb.2008.03.003
    • Juven-Gershon T, Hsu J-Y, Theisen JW, Kadonaga JT. The RNA polymerase II core promoter-the gateway to transcription. Curr Opin Cell Biol (2008) 20:253-9. doi:10.1016/j.ceb.2008.03.003.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 253-259
    • Juven-Gershon, T.1    Hsu, J.-Y.2    Theisen, J.W.3    Kadonaga, J.T.4
  • 8
    • 0043269205 scopus 로고    scopus 로고
    • The RNA polymerase II core promoter
    • doi:10.1146/annurev.biochem.72.121801.161520
    • Smale ST, Kadonaga JT. The RNA polymerase II core promoter. Annu Rev Biochem (2003) 72:449-79. doi:10.1146/annurev.biochem.72.121801.161520.
    • (2003) Annu Rev Biochem , vol.72 , pp. 449-479
    • Smale, S.T.1    Kadonaga, J.T.2
  • 9
    • 33847070442 scopus 로고    scopus 로고
    • The role of chromatin during transcription
    • doi:10.1016/j.cell.2007.01.015
    • Li B, Carey M, Workman JL. The role of chromatin during transcription. Cell (2007) 128:707-19. doi:10.1016/j.cell.2007.01.015.
    • (2007) Cell , vol.128 , pp. 707-719
    • Li, B.1    Carey, M.2    Workman, J.L.3
  • 10
    • 1842411320 scopus 로고    scopus 로고
    • Crystal structure of the nucleosome core particle at 2.8 A resolution
    • doi:10.1038/38444
    • Luger K, Mäder AW, Richmond RK, Sargent DF, Richmond TJ. Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature (1997) 389:251-60. doi:10.1038/38444.
    • (1997) Nature , vol.389 , pp. 251-260
    • Luger, K.1    Mäder, A.W.2    Richmond, R.K.3    Sargent, D.F.4    Richmond, T.J.5
  • 11
    • 79952534189 scopus 로고    scopus 로고
    • Regulation of chromatin by histone modifications
    • doi:10.1038/cr.2011.22
    • Bannister AJ, Kouzarides T. Regulation of chromatin by histone modifications. Cell Res (2011) 21:381-95. doi:10.1038/cr.2011.22.
    • (2011) Cell Res , vol.21 , pp. 381-395
    • Bannister, A.J.1    Kouzarides, T.2
  • 12
    • 79954416946 scopus 로고    scopus 로고
    • Readers of histone modifications
    • doi:10.1038/cr.2011.42
    • Yun M, Wu J, Workman JL, Li B. Readers of histone modifications. Cell Res (2011) 21:564-78. doi:10.1038/cr.2011.42.
    • (2011) Cell Res , vol.21 , pp. 564-578
    • Yun, M.1    Wu, J.2    Workman, J.L.3    Li, B.4
  • 13
    • 77952567987 scopus 로고    scopus 로고
    • Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
    • doi:10.1016/j.molcel.2010.05.004
    • Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P, et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell (2010) 38:576-89. doi:10.1016/j.molcel.2010.05.004.
    • (2010) Mol Cell , vol.38 , pp. 576-589
    • Heinz, S.1    Benner, C.2    Spann, N.3    Bertolino, E.4    Lin, Y.C.5    Laslo, P.6
  • 14
    • 77949977555 scopus 로고    scopus 로고
    • Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
    • doi:10.1016/j.immuni.2010.02.008
    • Ghisletti S, Barozzi I, Mietton F, Polletti S, De Santa F, Venturini E, et al. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity (2010) 32:317-28. doi:10.1016/j.immuni.2010.02.008.
    • (2010) Immunity , vol.32 , pp. 317-328
    • Ghisletti, S.1    Barozzi, I.2    Mietton, F.3    Polletti, S.4    De Santa, F.5    Venturini, E.6
  • 15
    • 0029617947 scopus 로고
    • Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome
    • doi:10.1016/0092-8674(95)90136-1
    • Thanos D, Maniatis T. Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome. Cell (1995) 83:1091-100. doi:10.1016/0092-8674(95)90136-1.
    • (1995) Cell , vol.83 , pp. 1091-1100
    • Thanos, D.1    Maniatis, T.2
  • 16
    • 0033681250 scopus 로고    scopus 로고
    • Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter
    • doi:10.1016/S0092-8674(00)00169-0
    • Agalioti T, Lomvardas S, Parekh B, Yie J, Maniatis T, Thanos D. Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter. Cell (2000) 103:667-78. doi:10.1016/S0092-8674(00)00169-0.
    • (2000) Cell , vol.103 , pp. 667-678
    • Agalioti, T.1    Lomvardas, S.2    Parekh, B.3    Yie, J.4    Maniatis, T.5    Thanos, D.6
  • 17
    • 77749242510 scopus 로고    scopus 로고
    • The transcriptional code of human IFN-beta gene expression
    • doi:10.1016/j.bbagrm.2010.01.010
    • Ford E, Thanos D. The transcriptional code of human IFN-beta gene expression. Biochim Biophys Acta (2010) 1799:328-36. doi:10.1016/j.bbagrm.2010.01.010.
    • (2010) Biochim Biophys Acta , vol.1799 , pp. 328-336
    • Ford, E.1    Thanos, D.2
  • 18
    • 0030872393 scopus 로고    scopus 로고
    • Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: evidence of functional synergy between C/EBP and Rel proteins
    • Plevy S, Gemberling JH, Hsu S, Donner AJ, Smale ST. Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: evidence of functional synergy between C/EBP and Rel proteins. Mol Cell Biol (1997) 17:4572-88.
    • (1997) Mol Cell Biol , vol.17 , pp. 4572-4588
    • Plevy, S.1    Gemberling, J.H.2    Hsu, S.3    Donner, A.J.4    Smale, S.T.5
  • 19
    • 0035947732 scopus 로고    scopus 로고
    • Characterization of an activation protein-1-binding site in the murine interleukin-12 p40 promoter. Demonstration of novel functional elements by a reductionist approach
    • doi:10.1074/jbc.M100440200
    • Zhu C, Gagnidze K, Gemberling JH, Plevy S. Characterization of an activation protein-1-binding site in the murine interleukin-12 p40 promoter. Demonstration of novel functional elements by a reductionist approach. J Biol Chem (2001) 276:18519-28. doi:10.1074/jbc.M100440200.
    • (2001) J Biol Chem , vol.276 , pp. 18519-18528
    • Zhu, C.1    Gagnidze, K.2    Gemberling, J.H.3    Plevy, S.4
  • 20
    • 0141960262 scopus 로고    scopus 로고
    • Activation of the murine interleukin-12 p40 promoter by functional interactions between NFAT and ICSBP
    • doi:10.1074/jbc.M306441200
    • Zhu C, Rao K, Xiong H, Gagnidze K, Li F, Horvath C, et al. Activation of the murine interleukin-12 p40 promoter by functional interactions between NFAT and ICSBP. J Biol Chem (2003) 278:39372-82. doi:10.1074/jbc.M306441200.
    • (2003) J Biol Chem , vol.278 , pp. 39372-39382
    • Zhu, C.1    Rao, K.2    Xiong, H.3    Gagnidze, K.4    Li, F.5    Horvath, C.6
  • 21
    • 0029143632 scopus 로고
    • Regulation of interleukin 12 p40 expression through an NF-kappa B half-site
    • Murphy T, Cleveland M, Kulesza P, Magram J, Murphy K. Regulation of interleukin 12 p40 expression through an NF-kappa B half-site. Mol Cell Biol (1995) 15:5258-67.
    • (1995) Mol Cell Biol , vol.15 , pp. 5258-5267
    • Murphy, T.1    Cleveland, M.2    Kulesza, P.3    Magram, J.4    Murphy, K.5
  • 22
    • 0033451474 scopus 로고    scopus 로고
    • Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription
    • doi:10.1016/S1074-7613(00)80141-7
    • Weinmann AS, Plevy S, Smale ST. Rapid and selective remodeling of a positioned nucleosome during the induction of IL-12 p40 transcription. Immunity (1999) 11:665-75. doi:10.1016/S1074-7613(00)80141-7.
    • (1999) Immunity , vol.11 , pp. 665-675
    • Weinmann, A.S.1    Plevy, S.2    Smale, S.T.3
  • 23
    • 0035221154 scopus 로고    scopus 로고
    • Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event
    • doi:10.1038/83168
    • Weinmann AS, Mitchell DM, Sanjabi S, Bradley MN, Hoffmann A, Liou HC, et al. Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event. Nat Immunol (2001) 2:51-7. doi:10.1038/83168.
    • (2001) Nat Immunol , vol.2 , pp. 51-57
    • Weinmann, A.S.1    Mitchell, D.M.2    Sanjabi, S.3    Bradley, M.N.4    Hoffmann, A.5    Liou, H.C.6
  • 24
    • 34147206377 scopus 로고    scopus 로고
    • An inducible enhancer required for Il12b promoter activity in an insulated chromatin environment
    • doi:10.1128/MCB.00788-06
    • Zhou L, Nazarian AA, Xu J, Tantin D, Corcoran LM, Smale ST. An inducible enhancer required for Il12b promoter activity in an insulated chromatin environment. Mol Cell Biol (2007) 27:2698-712. doi:10.1128/MCB.00788-06.
    • (2007) Mol Cell Biol , vol.27 , pp. 2698-2712
    • Zhou, L.1    Nazarian, A.A.2    Xu, J.3    Tantin, D.4    Corcoran, L.M.5    Smale, S.T.6
  • 25
    • 0035908126 scopus 로고    scopus 로고
    • Two waves of nuclear factor kappaB recruitment to target promoters
    • doi:10.1084/jem.193.12.1351
    • Saccani S, Pantano S, Natoli G. Two waves of nuclear factor kappaB recruitment to target promoters. J Exp Med (2001) 193:1351-9. doi:10.1084/jem.193.12.1351.
    • (2001) J Exp Med , vol.193 , pp. 1351-1359
    • Saccani, S.1    Pantano, S.2    Natoli, G.3
  • 26
    • 0028979476 scopus 로고
    • Structure of the NF-kappa B p50 homodimer bound to DNA
    • doi:10.1038/373311a0
    • Müller CW, Rey FA, Sodeoka M, Verdine GL, Harrison SC. Structure of the NF-kappa B p50 homodimer bound to DNA. Nature (1995) 373:311-7. doi:10.1038/373311a0.
    • (1995) Nature , vol.373 , pp. 311-317
    • Müller, C.W.1    Rey, F.A.2    Sodeoka, M.3    Verdine, G.L.4    Harrison, S.C.5
  • 27
    • 0032556894 scopus 로고    scopus 로고
    • Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA
    • doi:10.1038/34356
    • Chen FE, Huang D-B, Chen YQ, Ghosh G. Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA. Nature (1998) 391:410-3. doi:10.1038/34356.
    • (1998) Nature , vol.391 , pp. 410-413
    • Chen, F.E.1    Huang, D.-B.2    Chen, Y.Q.3    Ghosh, G.4
  • 28
    • 84858724192 scopus 로고    scopus 로고
    • NF-κB regulation: lessons from structures
    • doi:10.1111/j.1600-065X.2012.01097.x
    • Ghosh G, Wang VY-F, Huang D-B, Fusco A. NF-κB regulation: lessons from structures. Immunol Rev (2012) 246:36-58. doi:10.1111/j.1600-065X.2012.01097.x.
    • (2012) Immunol Rev , vol.246 , pp. 36-58
    • Ghosh, G.1    Wang, V.Y.-F.2    Huang, D.-B.3    Fusco, A.4
  • 29
    • 0030997719 scopus 로고    scopus 로고
    • Stable co-occupancy of transcription factors and histones at the HIV-1 enhancer
    • doi:10.1093/emboj/16.9.2463
    • Steger DJ, Workman JL. Stable co-occupancy of transcription factors and histones at the HIV-1 enhancer. EMBO J (1997) 16:2463-72. doi:10.1093/emboj/16.9.2463.
    • (1997) EMBO J , vol.16 , pp. 2463-2472
    • Steger, D.J.1    Workman, J.L.2
  • 30
    • 5644289433 scopus 로고    scopus 로고
    • The histone octamer is invisible when NF-kappaB binds to the nucleosome
    • doi:10.1074/jbc.M407235200
    • Angelov D, Lenouvel F, Hans F, Müller CW, Bouvet P, Bednar J, et al. The histone octamer is invisible when NF-kappaB binds to the nucleosome. J Biol Chem (2004) 279:42374-82. doi:10.1074/jbc.M407235200.
    • (2004) J Biol Chem , vol.279 , pp. 42374-42382
    • Angelov, D.1    Lenouvel, F.2    Hans, F.3    Müller, C.W.4    Bouvet, P.5    Bednar, J.6
  • 31
    • 84884693205 scopus 로고    scopus 로고
    • Binding of NF-κB to nucleosomes: effect of translational positioning, nucleosome remodeling and linker histone H1
    • doi:10.1371/journal.pgen.1003830
    • Lone IN, Shukla MS, Charles Richard JL, Peshev ZY, Dimitrov S, Angelov D. Binding of NF-κB to nucleosomes: effect of translational positioning, nucleosome remodeling and linker histone H1. PLoS Genet (2013) 9:e1003830. doi:10.1371/journal.pgen.1003830.
    • (2013) PLoS Genet , vol.9
    • Lone, I.N.1    Shukla, M.S.2    Charles Richard, J.L.3    Peshev, Z.Y.4    Dimitrov, S.5    Angelov, D.6
  • 32
    • 0036203419 scopus 로고    scopus 로고
    • The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1
    • doi:10.1016/S1097-2765(02)00477-X
    • Zhong H, May MJ, Jimi E, Ghosh S. The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol Cell (2002) 9:625-36. doi:10.1016/S1097-2765(02)00477-X.
    • (2002) Mol Cell , vol.9 , pp. 625-636
    • Zhong, H.1    May, M.J.2    Jimi, E.3    Ghosh, S.4
  • 33
    • 0038771214 scopus 로고    scopus 로고
    • Modulation of NF-kappaB activity by exchange of dimers
    • doi:10.1016/S1097-2765(03)00227-2
    • Saccani S, Pantano S, Natoli G. Modulation of NF-kappaB activity by exchange of dimers. Mol Cell (2003) 11:1563-74. doi:10.1016/S1097-2765(03)00227-2.
    • (2003) Mol Cell , vol.11 , pp. 1563-1574
    • Saccani, S.1    Pantano, S.2    Natoli, G.3
  • 34
    • 32044439558 scopus 로고    scopus 로고
    • Selective and antagonistic functions of SWI/SNF and Mi-2 beta nucleosome remodeling complexes during an inflammatory response
    • doi:10.1101/gad.1383206
    • Ramirez-Carrozzi VR, Nazarian AA, Li CC, Gore SL, Sridharan R, Imbalzano AN, et al. Selective and antagonistic functions of SWI/SNF and Mi-2 beta nucleosome remodeling complexes during an inflammatory response. Genes Dev (2006) 20:282-96. doi:10.1101/gad.1383206.
    • (2006) Genes Dev , vol.20 , pp. 282-296
    • Ramirez-Carrozzi, V.R.1    Nazarian, A.A.2    Li, C.C.3    Gore, S.L.4    Sridharan, R.5    Imbalzano, A.N.6
  • 35
    • 67649669255 scopus 로고    scopus 로고
    • A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling
    • doi:10.1016/j.cell.2009.04.020
    • Ramirez-Carrozzi VR, Braas D, Bhatt DM, Cheng CS, Hong C, Doty KR, et al. A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling. Cell (2009) 138:114-28. doi:10.1016/j.cell.2009.04.020.
    • (2009) Cell , vol.138 , pp. 114-128
    • Ramirez-Carrozzi, V.R.1    Braas, D.2    Bhatt, D.M.3    Cheng, C.S.4    Hong, C.5    Doty, K.R.6
  • 36
    • 67649648237 scopus 로고    scopus 로고
    • Control of inducible gene expression by signal-dependent transcriptional elongation
    • doi:10.1016/j.cell.2009.05.047
    • Hargreaves DC, Horng T, Medzhitov R. Control of inducible gene expression by signal-dependent transcriptional elongation. Cell (2009) 138:129-45. doi:10.1016/j.cell.2009.05.047.
    • (2009) Cell , vol.138 , pp. 129-145
    • Hargreaves, D.C.1    Horng, T.2    Medzhitov, R.3
  • 37
    • 79956330964 scopus 로고    scopus 로고
    • CpG islands and the regulation of transcription
    • doi:10.1101/gad.2037511
    • Deaton AM, Bird AP. CpG islands and the regulation of transcription. Genes Dev (2011) 25:1010-22. doi:10.1101/gad.2037511.
    • (2011) Genes Dev , vol.25 , pp. 1010-1022
    • Deaton, A.M.1    Bird, A.P.2
  • 38
    • 77951116072 scopus 로고    scopus 로고
    • CpG islands influence chromatin structure via the CpG-binding protein Cfp1
    • doi:10.1038/nature08924
    • Thomson JP, Skene PJ, Selfridge J, Clouaire T, Guy J, Webb S, et al. CpG islands influence chromatin structure via the CpG-binding protein Cfp1. Nature (2010) 464:1082-6. doi:10.1038/nature08924.
    • (2010) Nature , vol.464 , pp. 1082-1086
    • Thomson, J.P.1    Skene, P.J.2    Selfridge, J.3    Clouaire, T.4    Guy, J.5    Webb, S.6
  • 39
    • 29244438472 scopus 로고    scopus 로고
    • CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex
    • doi:10.1074/jbc.M508312200
    • Lee J-H, Skalnik DG. CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. J Biol Chem (2005) 280:41725-31. doi:10.1074/jbc.M508312200.
    • (2005) J Biol Chem , vol.280 , pp. 41725-41731
    • Lee, J.-H.1    Skalnik, D.G.2
  • 40
    • 84870485829 scopus 로고    scopus 로고
    • CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters
    • doi:10.1101/gr.138776.112
    • Fenouil R, Cauchy P, Koch F, Descostes N, Cabeza JZ, Innocenti C, et al. CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters. Genome Res (2012) 22:2399-408. doi:10.1101/gr.138776.112.
    • (2012) Genome Res , vol.22 , pp. 2399-2408
    • Fenouil, R.1    Cauchy, P.2    Koch, F.3    Descostes, N.4    Cabeza, J.Z.5    Innocenti, C.6
  • 41
    • 49349094024 scopus 로고    scopus 로고
    • Regulation of the RelA (p65) transactivation domain
    • doi:10.1042/BST0360603
    • O'Shea JM, Perkins ND. Regulation of the RelA (p65) transactivation domain. Biochem Soc Trans (2008) 36:603-8. doi:10.1042/BST0360603.
    • (2008) Biochem Soc Trans , vol.36 , pp. 603-608
    • O'Shea, J.M.1    Perkins, N.D.2
  • 42
    • 0037451357 scopus 로고    scopus 로고
    • Transcriptional activation of the NF-kappaB p65 subunit by mitogen-and stress-activated protein kinase-1 (MSK1)
    • doi:10.1093/emboj/cdg139
    • Vermeulen L, De Wilde G, Van Damme P, Vanden Berghe W, Haegeman G. Transcriptional activation of the NF-kappaB p65 subunit by mitogen-and stress-activated protein kinase-1 (MSK1). EMBO J (2003) 22:1313-24. doi:10.1093/emboj/cdg139.
    • (2003) EMBO J , vol.22 , pp. 1313-1324
    • Vermeulen, L.1    De Wilde, G.2    Van Damme, P.3    Vanden Berghe, W.4    Haegeman, G.5
  • 44
    • 77949540609 scopus 로고    scopus 로고
    • Pim-1 controls NF-kappaB signalling by stabilizing RelA/p65
    • doi:10.1038/cdd.2009.174
    • Nihira K, Ando Y, Yamaguchi T, Kagami Y, Miki Y, Yoshida K. Pim-1 controls NF-kappaB signalling by stabilizing RelA/p65. Cell Death Differ (2010) 17:689-98. doi:10.1038/cdd.2009.174.
    • (2010) Cell Death Differ , vol.17 , pp. 689-698
    • Nihira, K.1    Ando, Y.2    Yamaguchi, T.3    Kagami, Y.4    Miki, Y.5    Yoshida, K.6
  • 45
    • 0030991201 scopus 로고    scopus 로고
    • The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism
    • doi:10.1016/S0092-8674(00)80222-6
    • Zhong H, SuYang H, Erdjument-Bromage H, Tempst P, Ghosh S. The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism. Cell (1997) 89:413-24. doi:10.1016/S0092-8674(00)80222-6.
    • (1997) Cell , vol.89 , pp. 413-424
    • Zhong, H.1    SuYang, H.2    Erdjument-Bromage, H.3    Tempst, P.4    Ghosh, S.5
  • 46
    • 0032039076 scopus 로고    scopus 로고
    • Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
    • doi:10.1016/S1097-2765(00)80066-0
    • Zhong H, Voll RE, Ghosh S. Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol Cell (1998) 1:661-71. doi:10.1016/S1097-2765(00)80066-0.
    • (1998) Mol Cell , vol.1 , pp. 661-671
    • Zhong, H.1    Voll, R.E.2    Ghosh, S.3
  • 47
    • 43249114058 scopus 로고    scopus 로고
    • Repression of gene expression by unphosphorylated NF-kappaB p65 through epigenetic mechanisms
    • doi:10.1101/gad.1657408
    • Dong J, Jimi E, Zhong H, Hayden MS, Ghosh S. Repression of gene expression by unphosphorylated NF-kappaB p65 through epigenetic mechanisms. Genes Dev (2008) 22:1159-73. doi:10.1101/gad.1657408.
    • (2008) Genes Dev , vol.22 , pp. 1159-1173
    • Dong, J.1    Jimi, E.2    Zhong, H.3    Hayden, M.S.4    Ghosh, S.5
  • 48
    • 84884586171 scopus 로고    scopus 로고
    • Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription
    • doi:10.1371/journal.pbio.1001647
    • Mukherjee SP, Behar M, Birnbaum HA, Hoffmann A, Wright PE, Ghosh G. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS Biol (2013) 11:e1001647. doi:10.1371/journal.pbio.1001647.
    • (2013) PLoS Biol , vol.11
    • Mukherjee, S.P.1    Behar, M.2    Birnbaum, H.A.3    Hoffmann, A.4    Wright, P.E.5    Ghosh, G.6
  • 49
    • 67349285384 scopus 로고    scopus 로고
    • Negative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunit
    • doi:10.1038/emboj.2009.55
    • Yang X-D, Huang B, Li M, Lamb A, Kelleher NL, Chen L-F. Negative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunit. EMBO J (2009) 28:1055-66. doi:10.1038/emboj.2009.55.
    • (2009) EMBO J , vol.28 , pp. 1055-1066
    • Yang, X.-D.1    Huang, B.2    Li, M.3    Lamb, A.4    Kelleher, N.L.5    Chen, L.-F.6
  • 50
    • 77950642805 scopus 로고    scopus 로고
    • Functional interplay between acetylation and methylation of the RelA subunit of NF-kappaB
    • doi:10.1128/MCB.01343-09
    • Yang X-D, Tajkhorshid E, Chen L-F. Functional interplay between acetylation and methylation of the RelA subunit of NF-kappaB. Mol Cell Biol (2010) 30:2170-80. doi:10.1128/MCB.01343-09.
    • (2010) Mol Cell Biol , vol.30 , pp. 2170-2180
    • Yang, X.-D.1    Tajkhorshid, E.2    Chen, L.-F.3
  • 51
    • 84863248755 scopus 로고    scopus 로고
    • New molecular bridge between RelA/p65 and NF-κB target genes via histone acetyltransferase TIP60 cofactor
    • doi:10.1074/jbc.M111.278465
    • Kim J-W, Jang S-M, Kim C-H, An J-H, Kang E-J, Choi K-H. New molecular bridge between RelA/p65 and NF-κB target genes via histone acetyltransferase TIP60 cofactor. J Biol Chem (2012) 287:7780-91. doi:10.1074/jbc.M111.278465.
    • (2012) J Biol Chem , vol.287 , pp. 7780-7791
    • Kim, J.-W.1    Jang, S.-M.2    Kim, C.-H.3    An, J.-H.4    Kang, E.-J.5    Choi, K.-H.6
  • 52
    • 77953693097 scopus 로고    scopus 로고
    • Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway
    • doi:10.1016/j.cellsig.2010.03.017
    • Huang B, Yang X-D, Lamb A, Chen L-F. Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway. Cell Signal (2010) 22:1282-90. doi:10.1016/j.cellsig.2010.03.017.
    • (2010) Cell Signal , vol.22 , pp. 1282-1290
    • Huang, B.1    Yang, X.-D.2    Lamb, A.3    Chen, L.-F.4
  • 53
    • 33750457370 scopus 로고    scopus 로고
    • Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway
    • doi:10.1038/sj.onc.1209937
    • Perkins ND. Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway. Oncogene (2006) 25:6717-30. doi:10.1038/sj.onc.1209937.
    • (2006) Oncogene , vol.25 , pp. 6717-6730
    • Perkins, N.D.1
  • 54
    • 77956541159 scopus 로고    scopus 로고
    • A feed-forward circuit controlling inducible NF-κB target gene activation by promoter histone demethylation
    • doi:10.1016/j.molcel.2010.08.010
    • van Essen D, Zhu Y, Saccani S. A feed-forward circuit controlling inducible NF-κB target gene activation by promoter histone demethylation. Mol Cell (2010) 39:750-60. doi:10.1016/j.molcel.2010.08.010.
    • (2010) Mol Cell , vol.39 , pp. 750-760
    • van Essen, D.1    Zhu, Y.2    Saccani, S.3
  • 55
    • 0036712454 scopus 로고    scopus 로고
    • Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes
    • doi:10.1101/gad.232502
    • Saccani S, Natoli G. Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes. Genes Dev (2002) 16:2219-24. doi:10.1101/gad.232502.
    • (2002) Genes Dev , vol.16 , pp. 2219-2224
    • Saccani, S.1    Natoli, G.2
  • 56
    • 70350754328 scopus 로고    scopus 로고
    • Jmjd3 contributes to the control of gene expression in LPS-activated macrophages
    • doi:10.1038/emboj.2009.271
    • De Santa F, Narang V, Yap ZH, Tusi BK, Burgold T, Austenaa L, et al. Jmjd3 contributes to the control of gene expression in LPS-activated macrophages. EMBO J (2009) 28:3341-52. doi:10.1038/emboj.2009.271.
    • (2009) EMBO J , vol.28 , pp. 3341-3352
    • De Santa, F.1    Narang, V.2    Yap, Z.H.3    Tusi, B.K.4    Burgold, T.5    Austenaa, L.6
  • 57
    • 84865120905 scopus 로고    scopus 로고
    • A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
    • doi:10.1038/nature11262
    • Kruidenier L, Chung C, Cheng Z, Liddle J, Che K, Joberty G, et al. A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response. Nature (2012) 488:404-8. doi:10.1038/nature11262.
    • (2012) Nature , vol.488 , pp. 404-408
    • Kruidenier, L.1    Chung, C.2    Cheng, Z.3    Liddle, J.4    Che, K.5    Joberty, G.6
  • 58
    • 63049122784 scopus 로고    scopus 로고
    • Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways
    • doi:10.1101/gad.1773109
    • Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG, et al. Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev (2009) 23:681-93. doi:10.1101/gad.1773109.
    • (2009) Genes Dev , vol.23 , pp. 681-693
    • Ghisletti, S.1    Huang, W.2    Jepsen, K.3    Benner, C.4    Hardiman, G.5    Rosenfeld, M.G.6
  • 59
    • 67649668789 scopus 로고    scopus 로고
    • Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint
    • doi:10.1016/j.molcel.2009.05.023
    • Huang W, Ghisletti S, Perissi V, Rosenfeld MG, Glass CK. Transcriptional integration of TLR2 and TLR4 signaling at the NCoR derepression checkpoint. Mol Cell (2009) 35:48-57. doi:10.1016/j.molcel.2009.05.023.
    • (2009) Mol Cell , vol.35 , pp. 48-57
    • Huang, W.1    Ghisletti, S.2    Perissi, V.3    Rosenfeld, M.G.4    Glass, C.K.5
  • 60
    • 84867397456 scopus 로고    scopus 로고
    • Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20
    • doi:10.1016/j.molcel.2012.07.020
    • Stender JDD, Pascual G, Liu W, Kaikkonen MU, Do K, Spann NJJ, et al. Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20. Mol Cell (2012) 48:28-38. doi:10.1016/j.molcel.2012.07.020.
    • (2012) Mol Cell , vol.48 , pp. 28-38
    • Stender, J.D.D.1    Pascual, G.2    Liu, W.3    Kaikkonen, M.U.4    Do, K.5    Spann, N.J.J.6
  • 61
    • 84884821893 scopus 로고    scopus 로고
    • NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids
    • doi:10.1016/j.cell.2013.08.054
    • Li P, Spann NJ, Kaikkonen MU, Lu M, Oh DY, Fox JN, et al. NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids. Cell (2013) 155:200-14. doi:10.1016/j.cell.2013.08.054.
    • (2013) Cell , vol.155 , pp. 200-214
    • Li, P.1    Spann, N.J.2    Kaikkonen, M.U.3    Lu, M.4    Oh, D.Y.5    Fox, J.N.6
  • 62
    • 84867652835 scopus 로고    scopus 로고
    • Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages
    • doi:10.1073/pnas.1121131109
    • Chen X, Barozzi I, Termanini A, Prosperini E, Recchiuti A, Dalli J, et al. Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages. Proc Natl Acad Sci U S A (2012) 109:E2865-74. doi:10.1073/pnas.1121131109.
    • (2012) Proc Natl Acad Sci U S A , vol.109
    • Chen, X.1    Barozzi, I.2    Termanini, A.3    Prosperini, E.4    Recchiuti, A.5    Dalli, J.6
  • 63
    • 33748314757 scopus 로고    scopus 로고
    • Breaking barriers to transcription elongation
    • doi:10.1038/nrm1981
    • Saunders A, Core LJ, Lis JT. Breaking barriers to transcription elongation. Nat Rev Mol Cell Biol (2006) 7:557-67. doi:10.1038/nrm1981.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 557-567
    • Saunders, A.1    Core, L.J.2    Lis, J.T.3
  • 64
    • 70249104647 scopus 로고    scopus 로고
    • Defining mechanisms that regulate RNA polymerase II transcription in vivo
    • doi:10.1038/nature08449
    • Fuda NJ, Ardehali MB, Lis JT. Defining mechanisms that regulate RNA polymerase II transcription in vivo. Nature (2009) 461:186-92. doi:10.1038/nature08449.
    • (2009) Nature , vol.461 , pp. 186-192
    • Fuda, N.J.1    Ardehali, M.B.2    Lis, J.T.3
  • 65
    • 44649154972 scopus 로고    scopus 로고
    • The multi-tasking P-TEFb complex
    • doi:10.1016/j.ceb.2008.04.008
    • Brès V, Yoh SM, Jones KA. The multi-tasking P-TEFb complex. Curr Opin Cell Biol (2008) 20:334-40. doi:10.1016/j.ceb.2008.04.008.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 334-340
    • Brès, V.1    Yoh, S.M.2    Jones, K.A.3
  • 66
    • 78650566210 scopus 로고    scopus 로고
    • Pol II waiting in the starting gates: regulating the transition from transcription initiation into productive elongation
    • doi:10.1016/j.bbagrm.2010.11.001
    • Nechaev S, Adelman K. Pol II waiting in the starting gates: regulating the transition from transcription initiation into productive elongation. Biochim Biophys Acta (2011) 1809:34-45. doi:10.1016/j.bbagrm.2010.11.001.
    • (2011) Biochim Biophys Acta , vol.1809 , pp. 34-45
    • Nechaev, S.1    Adelman, K.2
  • 67
    • 1542314246 scopus 로고    scopus 로고
    • Elongation inhibition by DRB sensitivity-inducing factor is regulated by the A20 promoter via a novel negative element and NF-kappaB
    • doi:10.1128/MCB.24.6.2444-2454.2004
    • Ainbinder E, Amir-Zilberstein L, Yamaguchi Y, Handa H, Dikstein R. Elongation inhibition by DRB sensitivity-inducing factor is regulated by the A20 promoter via a novel negative element and NF-kappaB. Mol Cell Biol (2004) 24:2444-54. doi:10.1128/MCB.24.6.2444-2454.2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 2444-2454
    • Ainbinder, E.1    Amir-Zilberstein, L.2    Yamaguchi, Y.3    Handa, H.4    Dikstein, R.5
  • 68
    • 70849107088 scopus 로고    scopus 로고
    • Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling
    • doi:10.1073/pnas.0910177106
    • Adelman K, Kennedy MA, Nechaev S, Gilchrist DA, Muse GW, Chinenov Y, et al. Immediate mediators of the inflammatory response are poised for gene activation through RNA polymerase II stalling. Proc Natl Acad Sci U S A (2009) 106:18207-12. doi:10.1073/pnas.0910177106.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 18207-18212
    • Adelman, K.1    Kennedy, M.A.2    Nechaev, S.3    Gilchrist, D.A.4    Muse, G.W.5    Chinenov, Y.6
  • 69
    • 84860504575 scopus 로고    scopus 로고
    • Regulating the regulators: the pervasive effects of Pol II pausing on stimulus-responsive gene networks
    • doi:10.1101/gad.187781.112
    • Gilchrist DA, Fromm G, dos Santos G, Pham LN, McDaniel IE, Burkholder A, et al. Regulating the regulators: the pervasive effects of Pol II pausing on stimulus-responsive gene networks. Genes Dev (2012) 26:933-44. doi:10.1101/gad.187781.112.
    • (2012) Genes Dev , vol.26 , pp. 933-944
    • Gilchrist, D.A.1    Fromm, G.2    dos Santos, G.3    Pham, L.N.4    McDaniel, I.E.5    Burkholder, A.6
  • 70
    • 77953143038 scopus 로고    scopus 로고
    • RNA polymerase II stalling mediates cytokine gene expression
    • doi:10.4161/cc.9.4.10841
    • Adelman K, Rogatsky I. RNA polymerase II stalling mediates cytokine gene expression. Cell Cycle (2010) 9:630-1. doi:10.4161/cc.9.4.10841.
    • (2010) Cell Cycle , vol.9 , pp. 630-631
    • Adelman, K.1    Rogatsky, I.2
  • 71
    • 78650806593 scopus 로고    scopus 로고
    • Suppression of inflammation by a synthetic histone mimic
    • doi:10.1038/nature09589
    • Nicodeme E, Jeffrey KL, Schaefer U, Beinke S, Dewell S, Chung C, et al. Suppression of inflammation by a synthetic histone mimic. Nature (2010) 468:1119-23. doi:10.1038/nature09589.
    • (2010) Nature , vol.468 , pp. 1119-1123
    • Nicodeme, E.1    Jeffrey, K.L.2    Schaefer, U.3    Beinke, S.4    Dewell, S.5    Chung, C.6
  • 72
    • 61749088806 scopus 로고    scopus 로고
    • Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA
    • doi:10.1128/MCB.01365-08
    • Huang B, Yang X-D, Zhou M-M, Ozato K, Chen L-F. Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA. Mol Cell Biol (2009) 29:1375-87. doi:10.1128/MCB.01365-08.
    • (2009) Mol Cell Biol , vol.29 , pp. 1375-1387
    • Huang, B.1    Yang, X.-D.2    Zhou, M.-M.3    Ozato, K.4    Chen, L.-F.5
  • 73
    • 84866303839 scopus 로고    scopus 로고
    • A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals
    • doi:10.1016/j.molcel.2012.07.030
    • Garber M, Yosef N, Goren A, Raychowdhury R, Thielke A, Guttman M, et al. A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals. Mol Cell (2012) 47:810-22. doi:10.1016/j.molcel.2012.07.030.
    • (2012) Mol Cell , vol.47 , pp. 810-822
    • Garber, M.1    Yosef, N.2    Goren, A.3    Raychowdhury, R.4    Thielke, A.5    Guttman, M.6
  • 74
    • 65549104157 scopus 로고    scopus 로고
    • Histone modifications at human enhancers reflect global cell-type-specific gene expression
    • doi:10.1038/nature07829
    • Heintzman ND, Hon GC, Hawkins RD, Kheradpour P, Stark A, Harp LF, et al. Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature (2009) 459:108-12. doi:10.1038/nature07829.
    • (2009) Nature , vol.459 , pp. 108-112
    • Heintzman, N.D.1    Hon, G.C.2    Hawkins, R.D.3    Kheradpour, P.4    Stark, A.5    Harp, L.F.6
  • 75
    • 60149091656 scopus 로고    scopus 로고
    • ChIP-seq accurately predicts tissue-specific activity of enhancers
    • doi:10.1038/nature07730
    • Visel A, Blow MJ, Li Z, Zhang T, Akiyama JA, Holt A, et al. ChIP-seq accurately predicts tissue-specific activity of enhancers. Nature (2009) 457:854-8. doi:10.1038/nature07730.
    • (2009) Nature , vol.457 , pp. 854-858
    • Visel, A.1    Blow, M.J.2    Li, Z.3    Zhang, T.4    Akiyama, J.A.5    Holt, A.6
  • 76
    • 79951516056 scopus 로고    scopus 로고
    • A unique chromatin signature uncovers early developmental enhancers in humans
    • doi:10.1038/nature09692
    • Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J. A unique chromatin signature uncovers early developmental enhancers in humans. Nature (2011) 470:279-83. doi:10.1038/nature09692.
    • (2011) Nature , vol.470 , pp. 279-283
    • Rada-Iglesias, A.1    Bajpai, R.2    Swigut, T.3    Brugmann, S.A.4    Flynn, R.A.5    Wysocka, J.6
  • 77
    • 84872522528 scopus 로고    scopus 로고
    • Latent enhancers activated by stimulation in differentiated cells
    • doi:10.1016/j.cell.2012.12.018
    • Ostuni R, Piccolo V, Barozzi I, Polletti S, Termanini A, Bonifacio S, et al. Latent enhancers activated by stimulation in differentiated cells. Cell (2013) 152:157-71. doi:10.1016/j.cell.2012.12.018.
    • (2013) Cell , vol.152 , pp. 157-171
    • Ostuni, R.1    Piccolo, V.2    Barozzi, I.3    Polletti, S.4    Termanini, A.5    Bonifacio, S.6
  • 78
    • 34250823515 scopus 로고    scopus 로고
    • Gene-specific control of inflammation by TLR-induced chromatin modifications
    • doi:10.1038/nature05836
    • Foster SL, Hargreaves DC, Medzhitov R. Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature (2007) 447:972-8. doi:10.1038/nature05836.
    • (2007) Nature , vol.447 , pp. 972-978
    • Foster, S.L.1    Hargreaves, D.C.2    Medzhitov, R.3
  • 79
    • 84888641656 scopus 로고    scopus 로고
    • Effect of natural genetic variation on enhancer selection and function
    • doi:10.1038/nature12615
    • Heinz S, Romanoski CE, Benner C, Allison KA, Kaikkonen MU, Orozco LD, et al. Effect of natural genetic variation on enhancer selection and function. Nature (2013) 503:487-92. doi:10.1038/nature12615.
    • (2013) Nature , vol.503 , pp. 487-492
    • Heinz, S.1    Romanoski, C.E.2    Benner, C.3    Allison, K.A.4    Kaikkonen, M.U.5    Orozco, L.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.