Absence of AMPKα2 accelerates cellular senescence via p16 induction in mouse embryonic fibroblasts

International Journal of Biochemistry and Cell Biology

Volumn 71, Issue , 2016, Pages 72-80

  Ding, Ye ^a   Chen, Jie ^a   Okon, Imoh Sunday ^a   Zou, Ming Hui ^a   Song, Ping ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

AMPK 2; Cellular senescence; HBP1; p16; Reactive oxygen species

Indexed keywords

AMP ACTIVATED PROTEIN KINASE ALPHA 1; AMP ACTIVATED PROTEIN KINASE ALPHA 2; BETA GALACTOSIDASE; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; HETEROCHROMATIN PROTEIN 1; HETEROCHROMATIN PROTEIN 1 HOMOLOG GAMMA; HIGH MOBILITY GROUP B1 PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN P16; PROTEIN SERINE THREONINE KINASE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; AMPK ALPHA2 SUBUNIT, MOUSE; ANTIOXIDANT; HBP1 PROTEIN, MOUSE; HIGH MOBILITY GROUP PROTEIN; REPRESSOR PROTEIN;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL AGING; CELL CULTURE; CELL CYCLE ARREST; CELL ISOLATION; CONTROLLED STUDY; FIBROBLAST; GENE DELETION; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN FUNCTION; PROTEIN INDUCTION; RECEPTOR UPREGULATION; SKIN; WESTERN BLOTTING; WILD TYPE; ANIMAL; CYTOLOGY; DEFICIENCY; GENETIC TRANSCRIPTION; GENETICS; KINETICS; MAMMALIAN EMBRYO; METABOLISM; TRANSCRIPTION INITIATION; UPREGULATION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTIOXIDANTS; CELL AGING; CYCLIN-DEPENDENT KINASE INHIBITOR P16; EMBRYO, MAMMALIAN; FIBROBLASTS; GENE DELETION; HIGH MOBILITY GROUP PROTEINS; KINETICS; MICE; REACTIVE OXYGEN SPECIES; REPRESSOR PROTEINS; SKIN; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 84951980059     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2015.12.010     Document Type: Article

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