H3K9me-enhanced DNA hypermethylation of the p16INK4a gene: An epigenetic signature for spontaneous transformation of rat mesenchymal stem cells

Stem Cells and Development

Volumn 22, Issue 2, 2013, Pages 256-267

  Zheng, Yong ^a   He, Liu ^a   Wan, Yu ^a   Song, Jian ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; HISTONE H3; HISTONE H3 LYSINE 27; HISTONE H3 LYSINE 9; PROTEIN P21; RETINOBLASTOMA PROTEIN; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG;

ADULT STEM CELL; ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ARTICLE; CELL AGING; CELL CYCLE ARREST; CELL DIVISION; CELL IMMORTALIZATION; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; DNA METHYLATION; DNA MODIFICATION; DOWN REGULATION; EPIGENETICS; GENE; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; HISTONE METHYLATION; IN VITRO STUDY; MALE; MESENCHYMAL STEM CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; P16INK4A GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION;

ANIMALS; BIOLOGICAL MARKERS; BONE MARROW; CELL AGING; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CULTURE MEDIA; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA METHYLATION; EPIGENESIS, GENETIC; GENE KNOCKDOWN TECHNIQUES; HISTONES; LYSINE; MALE; MESENCHYMAL STROMAL CELLS; PHOSPHORYLATION; POLYCOMB REPRESSIVE COMPLEX 2; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING;

RATTUS;

EID: 84872441228     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2012.0172     Document Type: Article

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