Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function

Journal of Biological Chemistry

Volumn 278, Issue 29, 2003, Pages 27016-27023

  Wang, Wengong ^a   Yang, Xiaoling ^a   De Silanes, Isabel López ^a   Carling, David ^b   Gorospe, Myriam ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; PROTEINS; SODIUM COMPOUNDS;

PROTEIN KINASE;

BIOCHEMISTRY;

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOVIRUS VECTOR; ANTIMYCIN A1; BETA GALACTOSIDASE; GENE PRODUCT; HUR PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN KINASE; PROTEIN P16INK4A; RNA BINDING PROTEIN; SODIUM AZIDE; UNCLASSIFIED DRUG;

ARTICLE; CELL AGING; CELL GROWTH; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; EXPRESSION VECTOR; FIBROBLAST; GENE EXPRESSION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOTOPE LABELING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION;

ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOVIRIDAE; AMINO ACID SEQUENCE; AMINOIMIDAZOLE CARBOXAMIDE; ANTIGENS, SURFACE; ANTIMYCIN A; BASE SEQUENCE; BETA-GALACTOSIDASE; CELL AGING; CELL LINE; CYCLIN A; CYCLIN B; CYCLIN-DEPENDENT KINASE INHIBITOR P16; ENZYME ACTIVATION; FIBROBLASTS; GENES, FOS; GENETIC VECTORS; HUMANS; MULTIENZYME COMPLEXES; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT PROTEINS; RIBONUCLEOTIDES; RNA, MESSENGER; RNA-BINDING PROTEINS; SODIUM AZIDE; TRANSFECTION;

ADENOVIRIDAE; VECTORS;

EID: 0038035142     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300318200     Document Type: Article

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