메뉴 건너뛰기




Volumn 17, Issue 1, 2016, Pages 45-59

Neurobiology of rodent self-grooming and its value for translational neuroscience

Author keywords

[No Author keywords available]

Indexed keywords

AUTISM; CENTRAL NERVOUS SYSTEM DISEASE; COMPULSION; EXTRAPYRAMIDAL SYNDROME; GROOMING; NEUROBIOLOGY; NONHUMAN; OBSESSIVE COMPULSIVE DISORDER; PHENOTYPE; PRIORITY JOURNAL; REVIEW; RODENT MODEL; SELF GROOMING; ANIMAL; ANIMAL BEHAVIOR; DISEASE MODEL; GENETICS; HUMAN; PATHOPHYSIOLOGY; PHYSIOLOGY;

EID: 84950988164     PISSN: 1471003X     EISSN: 14710048     Source Type: Journal    
DOI: 10.1038/nrn.2015.8     Document Type: Review
Times cited : (553)

References (201)
  • 1
    • 0023772942 scopus 로고
    • An ethological analysis of excessive grooming in young and aged rats
    • Spruijt, B. M., Welbergen, P., Brakkee, J. & Gispen, W. H. An ethological analysis of excessive grooming in young and aged rats. Ann. NY Acad. Sci. 525, 89-100 (1988).
    • (1988) Ann. NY Acad. Sci , vol.525 , pp. 89-100
    • Spruijt, B.M.1    Welbergen, P.2    Brakkee, J.3    Gispen, W.H.4
  • 2
    • 0026764860 scopus 로고
    • Ethology and neurobiology of grooming behavior
    • Spruijt, B. M., van Hooff, J. A. & Gispen, W. H. Ethology and neurobiology of grooming behavior. Physiol. Rev. 72, 825-852 (1992).
    • (1992) Physiol. Rev , vol.72 , pp. 825-852
    • Spruijt, B.M.1    Van Hooff, J.A.2    Gispen, W.H.3
  • 3
    • 0014252066 scopus 로고
    • Interrupted ongoing behaviour in two species of vole (microtus agrestis and clethrionomys britannicus). II. Extended analysis of motivational variables underlying fleeing and grooming behaviour
    • Fentress, J. C. Interrupted ongoing behaviour in two species of vole (Microtus agrestis and Clethrionomys britannicus). II. Extended analysis of motivational variables underlying fleeing and grooming behaviour. Anim. Behav. 16, 154-167 (1968).
    • (1968) Anim. Behav , vol.16 , pp. 154-167
    • Fentress, J.C.1
  • 4
    • 0014252065 scopus 로고
    • Interrupted ongoing behaviour in two species of vole (microtus agrestis and clethrionomys britannicus). I. Response as a function of preceding activity and the context of an apparently "irrelevant" motor pattern
    • Fentress, J. C. Interrupted ongoing behaviour in two species of vole (Microtus agrestis and Clethrionomys britannicus). I. Response as a function of preceding activity and the context of an apparently "irrelevant" motor pattern. Anim. Behav. 16, 135-153 (1968).
    • (1968) Anim. Behav , vol.16 , pp. 135-153
    • Fentress, J.C.1
  • 5
    • 22544447381 scopus 로고    scopus 로고
    • The role of prolactin and testosterone in mediating seasonal differences in the self-grooming behavior of male meadow voles microtus pennsylvanicus
    • Leonard, S. T., Alizadeh-Naderi, R., Stokes, K. & Ferkin, M. H. The role of prolactin and testosterone in mediating seasonal differences in the self-grooming behavior of male meadow voles, Microtus pennsylvanicus. Physiol. Behav. 85, 461-468 (2005).
    • (2005) Physiol. Behav , vol.85 , pp. 461-468
    • Leonard, S.T.1    Alizadeh-Naderi, R.2    Stokes, K.3    Ferkin, M.H.4
  • 6
    • 80053547934 scopus 로고    scopus 로고
    • (Cambridge Univ. Press This book provides a comprehensive overview of animal self-grooming and its relevance to human behaviours
    • Kalueff, A., LaPorte, J. L. & Bergner, C. Neurobiology of Grooming Behavior (Cambridge Univ. Press, 2010). This book provides a comprehensive overview of animal self-grooming and its relevance to human behaviours.
    • (2010) Neurobiology of Grooming Behavior
    • Kalueff, A.1    LaPorte, J.L.2    Bergner, C.3
  • 8
    • 0034284889 scopus 로고    scopus 로고
    • Super-stereotypy II: Enhancement of a complex movement sequence by intraventricular dopamine d1 agonists
    • Berridge, K. C. & Aldridge, J. W. Super-stereotypy II: enhancement of a complex movement sequence by intraventricular dopamine D1 agonists. Synapse 37, 205-215 (2000).
    • (2000) Synapse , vol.37 , pp. 205-215
    • Berridge, K.C.1    Aldridge, J.W.2
  • 9
    • 0023119611 scopus 로고
    • Natural syntax rules control action sequence of rats
    • An important description of natural sequence 'syntax' in rodent grooming
    • Berridge, K. C., Fentress, J. C. & Parr, H. Natural syntax rules control action sequence of rats. Behav. Brain Res. 23, 59-68 (1987). An important description of natural sequence 'syntax' in rodent grooming.
    • (1987) Behav. Brain Res , vol.23 , pp. 59-68
    • Berridge, K.C.1    Fentress, J.C.2    Parr, H.3
  • 10
    • 0022394599 scopus 로고
    • Early ontogeny of face grooming in mice
    • Golani, I. & Fentress, J. C. Early ontogeny of face grooming in mice. Dev. Psychobiol. 18, 529-544 (1985).
    • (1985) Dev. Psychobiol , vol.18 , pp. 529-544
    • Golani, I.1    Fentress, J.C.2
  • 11
    • 0021272498 scopus 로고
    • Behavioral sequences as an easily quantifiable parameter in experimental studies
    • Spruijt, B. M. & Gispen, W. H. Behavioral sequences as an easily quantifiable parameter in experimental studies. Physiol. Behav. 32, 707-710 (1985).
    • (1985) Physiol. Behav , vol.32 , pp. 707-710
    • Spruijt, B.M.1    Gispen, W.H.2
  • 12
    • 84906056738 scopus 로고    scopus 로고
    • Parasites enhance self-grooming behaviour and information retention in humans
    • Prokop, P., Fancovicova, J. & Fedor, P. Parasites enhance self-grooming behaviour and information retention in humans. Behav. Processes 107, 42-46 (2014).
    • (2014) Behav. Processes , vol.107 , pp. 42-46
    • Prokop, P.1    Fancovicova, J.2    Fedor, P.3
  • 13
    • 33947716591 scopus 로고    scopus 로고
    • Dressing and grooming: Preferences of community-dwelling older adults
    • Cohen-Mansfield, J. & Jensen, B. Dressing and grooming: preferences of community-dwelling older adults. J. Gerontol. Nurs. 33, 31-39 (2007).
    • (2007) J. Gerontol. Nurs , vol.33 , pp. 31-39
    • Cohen-Mansfield, J.1    Jensen, B.2
  • 14
    • 84869445247 scopus 로고    scopus 로고
    • Potential translational targets revealed by linking mouse grooming behavioral phenotypes to gene expression using public databases
    • Roth, A. et al. Potential translational targets revealed by linking mouse grooming behavioral phenotypes to gene expression using public databases. Prog. Neuropsychopharmacol. Biol. Psychiatry 40, 312-325 (2013).
    • (2013) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.40 , pp. 312-325
    • Roth, A.1
  • 15
    • 84878766316 scopus 로고    scopus 로고
    • Repeated cortico-striatal stimulation generates persistent ocd-like behavior
    • An important study that demonstrated that chronic optogenetic stimulation of the cortico-striatal pathway induces repetitive OCD-like grooming behaviour in mice
    • Ahmari, S. E. et al. Repeated cortico-striatal stimulation generates persistent OCD-like behavior. Science 340, 1234-1239 (2013). An important study that demonstrated that chronic optogenetic stimulation of the cortico-striatal pathway induces repetitive OCD-like grooming behaviour in mice.
    • (2013) Science , vol.340 , pp. 1234-1239
    • Ahmari, S.E.1
  • 16
    • 84862274500 scopus 로고    scopus 로고
    • Autistic-like behaviours and hyperactivity in mice lacking prosap1/shank2
    • A critical, authoritative evaluation of the behaviour of mice with mutations in Shank genes, which suggests that these genes have a role in psychiatric diseases
    • Schmeisser, M. J. et al. Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature 486, 256-260 (2012). A critical, authoritative evaluation of the behaviour of mice with mutations in Shank genes, which suggests that these genes have a role in psychiatric diseases.
    • (2012) Nature , vol.486 , pp. 256-260
    • Schmeisser, M.J.1
  • 17
    • 77953282828 scopus 로고    scopus 로고
    • Hematopoietic origin of pathological grooming in hoxb8 mutant mice
    • Chen, S. K. et al. Hematopoietic origin of pathological grooming in Hoxb8 mutant mice. Cell 141, 775-785 (2010).
    • (2010) Cell , vol.141 , pp. 775-785
    • Chen, S.K.1
  • 18
    • 77952243965 scopus 로고    scopus 로고
    • Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice
    • Shmelkov, S. V. et al. Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice. Nat. Med. 16, 598-602 (2010).
    • (2010) Nat. Med , vol.16 , pp. 598-602
    • Shmelkov, S.V.1
  • 19
    • 84904739369 scopus 로고    scopus 로고
    • Oxotremorine treatment reduces repetitive behaviors in btbr t+ tf/j mice
    • Amodeo, D. A., Yi, J., Sweeney, J. A. & Ragozzino, M. E. Oxotremorine treatment reduces repetitive behaviors in BTBR T+ tf/J mice. Front. Synaptic Neurosci. 6, 17 (2014).
    • (2014) Front. Synaptic Neurosci , vol.6 , pp. 17
    • Amodeo, D.A.1    Yi, J.2    Sweeney, J.A.3    Ragozzino, M.E.4
  • 20
    • 84888782973 scopus 로고    scopus 로고
    • Repetitive behavior profile and supersensitivity to amphetamine in the c58/j mouse model of autism
    • Moy, S. S. et al. Repetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism. Behav. Brain Res. 259, 200-214 (2014).
    • (2014) Behav. Brain Res , vol.259 , pp. 200-214
    • Moy, S.S.1
  • 21
    • 84905381699 scopus 로고    scopus 로고
    • Repetitive behaviors in the shank1 knockout mouse model for autism spectrum disorder: Developmental aspects and effects of social context
    • Sungur, A. O., Vorckel, K. J., Schwarting, R. K. & Wohr, M. Repetitive behaviors in the Shank1 knockout mouse model for autism spectrum disorder: developmental aspects and effects of social context. J. Neurosci. Methods 234, 92-100 (2014).
    • (2014) J. Neurosci. Methods , vol.234 , pp. 92-100
    • Sungur, A.O.1    Vorckel, K.J.2    Schwarting, R.K.3    Wohr, M.4
  • 22
    • 84880332828 scopus 로고    scopus 로고
    • Autism-related behavioral abnormalities in synapsin knockout mice
    • Greco, B. et al. Autism-related behavioral abnormalities in synapsin knockout mice. Behav. Brain Res. 251, 65-74 (2013).
    • (2013) Behav. Brain Res , vol.251 , pp. 65-74
    • Greco, B.1
  • 23
    • 84879549441 scopus 로고    scopus 로고
    • Double deletion of melanocortin 4 receptors and sapap3 corrects compulsive behavior and obesity in mice
    • Xu, P. et al. Double deletion of melanocortin 4 receptors and SAPAP3 corrects compulsive behavior and obesity in mice. Proc. Natl Acad. Sci. USA 110, 10759-10764 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 10759-10764
    • Xu, P.1
  • 24
    • 0037012077 scopus 로고    scopus 로고
    • A genetic basis for obsessive grooming
    • Graybiel, A. M. & Saka, E. A genetic basis for obsessive grooming. Neuron 33, 1-2 (2002).
    • (2002) Neuron , vol.33 , pp. 1-2
    • Graybiel, A.M.1    Saka, E.2
  • 25
    • 0037012082 scopus 로고    scopus 로고
    • Hoxb8 is required for normal grooming behavior in mice
    • Greer, J. M. & Capecchi, M. R. Hoxb8 is required for normal grooming behavior in mice. Neuron 33, 23-34 (2002).
    • (2002) Neuron , vol.33 , pp. 23-34
    • Greer, J.M.1    Capecchi, M.R.2
  • 26
    • 0023764869 scopus 로고
    • Expressive contexts, fine structure, and central mediation of rodent grooming
    • Fentress, J. C. Expressive contexts, fine structure, and central mediation of rodent grooming. Ann. NY Acad. Sci. 525, 18-26 (1988).
    • (1988) Ann. NY Acad. Sci , vol.525 , pp. 18-26
    • Fentress, J.C.1
  • 27
    • 7044269249 scopus 로고    scopus 로고
    • Contrasting grooming phenotypes in c57bl/6 and 129s1/svimj mice
    • Kalueff, A. V. & Tuohimaa, P. Contrasting grooming phenotypes in C57Bl/6 and 129S1/SvImJ mice. Brain Res. 1028, 75-82 (2004).
    • (2004) Brain Res , vol.1028 , pp. 75-82
    • Kalueff, A.V.1    Tuohimaa, P.2
  • 28
    • 3543143666 scopus 로고    scopus 로고
    • Grooming analysis algorithm for neurobehavioural stress research
    • Kalueff, A. V. & Tuohimaa, P. Grooming analysis algorithm for neurobehavioural stress research. Brain Res. Protoc. 13, 151-158 (2004).
    • (2004) Brain Res. Protoc , vol.13 , pp. 151-158
    • Kalueff, A.V.1    Tuohimaa, P.2
  • 29
    • 27544468773 scopus 로고    scopus 로고
    • Sequential super-stereotypy of an instinctive fixed action pattern in hyper-dopaminergic mutant mice: A model of obsessive compulsive disorder and tourette's
    • Berridge, K. C., Aldridge, J. W., Houchard, K. R. & Zhuang, X. Sequential super-stereotypy of an instinctive fixed action pattern in hyper-dopaminergic mutant mice: a model of obsessive compulsive disorder and Tourette's. BMC Biol. 3, 4 (2005).
    • (2005) BMC Biol , vol.3 , pp. 4
    • Berridge, K.C.1    Aldridge, J.W.2    Houchard, K.R.3    Zhuang, X.4
  • 30
    • 16244368778 scopus 로고    scopus 로고
    • The grooming analysis algorithm discriminates between different levels of anxiety in rats: Potential utility for neurobehavioural stress research
    • Kalueff, A. V. & Tuohimaa, P. The grooming analysis algorithm discriminates between different levels of anxiety in rats: potential utility for neurobehavioural stress research. J. Neurosci. Methods 143, 169-177 (2005).
    • (2005) J. Neurosci. Methods , vol.143 , pp. 169-177
    • Kalueff, A.V.1    Tuohimaa, P.2
  • 31
    • 3242778513 scopus 로고    scopus 로고
    • Increased grooming behavior in mice lacking Vitamin D receptors
    • Kalueff, A. V., Lou, Y. R., Laaksi, I. & Tuohimaa, P. Increased grooming behavior in mice lacking vitamin D receptors. Physiol. Behav. 82, 405-409 (2004).
    • (2004) Physiol. Behav , vol.82 , pp. 405-409
    • Kalueff, A.V.1    Lou, Y.R.2    Laaksi, I.3    Tuohimaa, P.4
  • 32
    • 12844281340 scopus 로고    scopus 로고
    • Mouse grooming microstructure is a reliable anxiety marker bidirectionally sensitive to gabaergic drugs
    • Kalueff, A. V. & Tuohimaa, P. Mouse grooming microstructure is a reliable anxiety marker bidirectionally sensitive to GABAergic drugs. Eur. J. Pharmacol. 508, 147-153 (2005).
    • (2005) Eur. J. Pharmacol , vol.508 , pp. 147-153
    • Kalueff, A.V.1    Tuohimaa, P.2
  • 33
    • 84884173493 scopus 로고    scopus 로고
    • Effects of environmental enrichment on repetitive behaviors in the btbr t+tf/j mouse model of autism
    • Reynolds, S., Urruela, M. & Devine, D. P. Effects of environmental enrichment on repetitive behaviors in the BTBR T+tf/J mouse model of autism. Autism Res. 6, 337-343 (2013).
    • (2013) Autism Res , vol.6 , pp. 337-343
    • Reynolds, S.1    Urruela, M.2    Devine, D.P.3
  • 34
    • 0029881870 scopus 로고    scopus 로고
    • Implementation of action sequences by a neostriatal site: A lesion mapping study of grooming syntax
    • Cromwell, H. C. & Berridge, K. C. Implementation of action sequences by a neostriatal site: a lesion mapping study of grooming syntax. J. Neurosci. 16, 3444-3458 (1996).
    • (1996) J. Neurosci , vol.16 , pp. 3444-3458
    • Cromwell, H.C.1    Berridge, K.C.2
  • 35
    • 0024375396 scopus 로고
    • Progressive degradation of serial grooming chains by descending decerebration
    • Berridge, K. C. Progressive degradation of serial grooming chains by descending decerebration. Behav. Brain Res. 33, 241-253 (1989).
    • (1989) Behav. Brain Res , vol.33 , pp. 241-253
    • Berridge, K.C.1
  • 36
  • 37
    • 84896722491 scopus 로고    scopus 로고
    • Basal ganglia subcircuits distinctively encode the parsing and concatenation of action sequences
    • Jin, X., Tecuapetla, F. & Costa, R. M. Basal ganglia subcircuits distinctively encode the parsing and concatenation of action sequences. Nat. Neurosci. 17, 423-430 (2014).
    • (2014) Nat. Neurosci , vol.17 , pp. 423-430
    • Jin, X.1    Tecuapetla, F.2    Costa, R.M.3
  • 38
    • 84901604929 scopus 로고    scopus 로고
    • Working together: Basal ganglia pathways in action selection
    • Friend, D. M. & Kravitz, A. V. Working together: basal ganglia pathways in action selection. Trends Neurosci. 37, 301-303 (2014).
    • (2014) Trends Neurosci , vol.37 , pp. 301-303
    • Friend, D.M.1    Kravitz, A.V.2
  • 39
    • 84878750990 scopus 로고    scopus 로고
    • Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors
    • Burguiere, E., Monteiro, P., Feng, G. & Graybiel, A. M. Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors. Science 340, 1243-1246 (2013).
    • (2013) Science , vol.340 , pp. 1243-1246
    • Burguiere, E.1    Monteiro, P.2    Feng, G.3    Graybiel, A.M.4
  • 40
    • 34548147472 scopus 로고    scopus 로고
    • Cortico-striatal synaptic defects and ocd-like behaviours in sapap3-mutant mice
    • Welch, J. M. et al. Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice. Nature 448, 894-900 (2007).
    • (2007) Nature , vol.448 , pp. 894-900
    • Welch, J.M.1
  • 41
    • 11244310623 scopus 로고    scopus 로고
    • Basal ganglia neural mechanisms of natural movement sequences
    • Aldridge, J. W., Berridge, K. C. & Rosen, A. R. Basal ganglia neural mechanisms of natural movement sequences. Can. J. Physiol. Pharmacol. 82, 732-739 (2004).
    • (2004) Can. J. Physiol. Pharmacol , vol.82 , pp. 732-739
    • Aldridge, J.W.1    Berridge, K.C.2    Rosen, A.R.3
  • 42
    • 48249091260 scopus 로고    scopus 로고
    • Habits rituals, and the evaluative brain
    • Graybiel, A. M. Habits, rituals, and the evaluative brain. Annu. Rev. Neurosci. 31, 359-387 (2008).
    • (2008) Annu. Rev. Neurosci , vol.31 , pp. 359-387
    • Graybiel, A.M.1
  • 44
    • 0026669250 scopus 로고
    • Cortex striatum and cerebellum: Control of serial order in a grooming sequence
    • Berridge, K. C. & Whishaw, I. Q. Cortex, striatum and cerebellum: control of serial order in a grooming sequence. Exp. Brain Res. 90, 275-290 (1992).
    • (1992) Exp. Brain Res , vol.90 , pp. 275-290
    • Berridge, K.C.1    Whishaw, I.Q.2
  • 45
    • 0018246166 scopus 로고
    • Behavior maintained by electrical stimulation of the rat cerebellum
    • Watson, P. J. Behavior maintained by electrical stimulation of the rat cerebellum. Physiol. Behav. 21, 749-755 (1978).
    • (1978) Physiol. Behav , vol.21 , pp. 749-755
    • Watson, P.J.1
  • 46
    • 0031832989 scopus 로고    scopus 로고
    • Grooming in lurcher mutant mice
    • Strazielle, C. & Lalonde, R. Grooming in Lurcher mutant mice. Physiol. Behav. 64, 57-61 (1998).
    • (1998) Physiol. Behav , vol.64 , pp. 57-61
    • Strazielle, C.1    Lalonde, R.2
  • 47
    • 84908077048 scopus 로고    scopus 로고
    • Antagonistic control of social versus repetitive self-grooming behaviors by separable amygdala neuronal subsets
    • Hong, W., Kim, D. W. & Anderson, D. J. Antagonistic control of social versus repetitive self-grooming behaviors by separable amygdala neuronal subsets. Cell 158, 1348-1361 (2014).
    • (2014) Cell , vol.158 , pp. 1348-1361
    • Hong, W.1    Kim, D.W.2    Anderson, D.J.3
  • 48
    • 0036459964 scopus 로고    scopus 로고
    • Enhanced motivation to self-Administer cocaine is predicted by self-grooming behaviour and relates to dopamine release in the rat medial prefrontal cortex and amygdala
    • Homberg, J. R. et al. Enhanced motivation to self-Administer cocaine is predicted by self-grooming behaviour and relates to dopamine release in the rat medial prefrontal cortex and amygdala. Eur. J. Neurosci. 15, 1542-1550 (2002).
    • (2002) Eur. J. Neurosci , vol.15 , pp. 1542-1550
    • Homberg, J.R.1
  • 49
    • 84926419393 scopus 로고    scopus 로고
    • Central amygdalar nucleus treated with orexin nEuropeptides evoke differing feeding and grooming responses in the hamster
    • Alo, R., Avolio, E., Mele, M., Di Vito, A. & Canonaco, M. Central amygdalar nucleus treated with orexin nEuropeptides evoke differing feeding and grooming responses in the hamster. J. Neurol. Sci. 351, 46-51 (2015).
    • (2015) J. Neurol. Sci , vol.351 , pp. 46-51
    • Alo, R.1    Avolio, E.2    Mele, M.3    Di Vito, A.4    Canonaco, M.5
  • 50
    • 84862310662 scopus 로고    scopus 로고
    • Past present, and future of the pathophysiological model of the basal ganglia
    • A comprehensive review of basal ganglia circuitry and functions in the brain, with a particular focus on complex patterned behaviours
    • Obeso, J. A. & Lanciego, J. L. Past, present, and future of the pathophysiological model of the basal ganglia. Front. Neuroanat. 5, 39 (2011). A comprehensive review of basal ganglia circuitry and functions in the brain, with a particular focus on complex patterned behaviours.
    • (2011) Front. Neuroanat , vol.5 , pp. 39
    • Obeso, J.A.1    Lanciego, J.L.2
  • 51
    • 84930485706 scopus 로고    scopus 로고
    • A corticostriatal path targeting striosomes controls decision-making under conflict
    • Friedman, A. et al. A corticostriatal path targeting striosomes controls decision-making under conflict. Cell 161, 1320-1333 (2015).
    • (2015) Cell , vol.161 , pp. 1320-1333
    • Friedman, A.1
  • 54
    • 35148901023 scopus 로고    scopus 로고
    • Quest for the basic plan of nervous system circuitry
    • Swanson, L. W. Quest for the basic plan of nervous system circuitry. Brain Res. Rev. 55, 356-372 (2007).
    • (2007) Brain Res. Rev , vol.55 , pp. 356-372
    • Swanson, L.W.1
  • 55
    • 84947280588 scopus 로고    scopus 로고
    • Regulation of the mesocorticolimbic and mesostriatal dopamine systems by alpha-melanocyte stimulating hormone and agouti-related protein
    • Roseberry, A. G., Stuhrman, K. & Dunigan, A. I. Regulation of the mesocorticolimbic and mesostriatal dopamine systems by alpha-melanocyte stimulating hormone and agouti-related protein. Neurosci. Biobehav Rev. 56, 15-25 (2015).
    • (2015) Neurosci. Biobehav Rev , vol.56 , pp. 15-25
    • Roseberry, A.G.1    Stuhrman, K.2    Dunigan, A.I.3
  • 56
    • 0023793681 scopus 로고
    • Studies on the neurochemical mechanisms and significance of acth-induced grooming
    • Dunn, A. J. Studies on the neurochemical mechanisms and significance of ACTH-induced grooming. Ann. NY Acad. Sci. 525, 150-168 (1988).
    • (1988) Ann. NY Acad. Sci , vol.525 , pp. 150-168
    • Dunn, A.J.1
  • 57
    • 0018427567 scopus 로고
    • Intracerebral adrenocorticotropic hormone mediates novelty-induced grooming in the rat
    • Dunn, A. J., Green, E. J. & Isaacson, R. L. Intracerebral adrenocorticotropic hormone mediates novelty-induced grooming in the rat. Science 203, 281-283 (1979).
    • (1979) Science , vol.203 , pp. 281-283
    • Dunn, A.J.1    Green, E.J.2    Isaacson, R.L.3
  • 58
    • 0023413592 scopus 로고
    • Crf-induced excessive grooming behavior in rats and mice
    • Dunn, A. J., Berridge, C. W., Lai, Y. I. & Yachabach, T. L. CRF-induced excessive grooming behavior in rats and mice. Peptides 8, 841-844 (1987).
    • (1987) Peptides , vol.8 , pp. 841-844
    • Dunn, A.J.1    Berridge, C.W.2    Lai, Y.I.3    Yachabach, T.L.4
  • 59
    • 0017682131 scopus 로고
    • Mesolimbic involvement in the locomotor stimulant action of thyrotropin-releasing hormone (trh) in rats
    • Miyamoto, M. & Nagawa, Y. Mesolimbic involvement in the locomotor stimulant action of thyrotropin-releasing hormone (TRH) in rats. Eur. J. Pharmacol. 44, 143-152 (1977).
    • (1977) Eur. J. Pharmacol , vol.44 , pp. 143-152
    • Miyamoto, M.1    Nagawa, Y.2
  • 60
    • 0029896855 scopus 로고    scopus 로고
    • Thyrotropin releasing hormone injected into the nucleus accumbens septi selectively increases face grooming in rats
    • Gargiulo, P. A. Thyrotropin releasing hormone injected into the nucleus accumbens septi selectively increases face grooming in rats. Braz. J. Med. Biol. Res. 29, 805-810 (1996).
    • (1996) Braz. J. Med. Biol. Res , vol.29 , pp. 805-810
    • Gargiulo, P.A.1
  • 61
    • 0035714671 scopus 로고    scopus 로고
    • Correlation of increased grooming behavior and motor activity with alterations in nigrostriatal and mesolimbic catecholamines after alpha-melanotropin and nEuropeptide glutamine-isoleucine injection in the rat ventral tegmental area
    • Sanchez, M. S., Barontini, M., Armando, I. & Celis, M. E. Correlation of increased grooming behavior and motor activity with alterations in nigrostriatal and mesolimbic catecholamines after alpha-melanotropin and nEuropeptide glutamine-isoleucine injection in the rat ventral tegmental area. Cell. Mol. Neurobiol. 21, 523-533 (2001).
    • (2001) Cell. Mol. Neurobiol , vol.21 , pp. 523-533
    • Sanchez, M.S.1    Barontini, M.2    Armando, I.3    Celis, M.E.4
  • 62
    • 0032422183 scopus 로고    scopus 로고
    • The hypothalamus: Cross-roads of endocrine and behavioural regulation in grooming and aggression
    • Kruk, M. R. et al. The hypothalamus: cross-roads of endocrine and behavioural regulation in grooming and aggression. Neurosci. Biobehav. Rev. 23, 163-177 (1998).
    • (1998) Neurosci. Biobehav. Rev , vol.23 , pp. 163-177
    • Kruk, M.R.1
  • 63
    • 0034285031 scopus 로고    scopus 로고
    • Super-stereotypy i: Enhancement of a complex movement sequence by systemic dopamine d1 agonists
    • Berridge, K. C. & Aldridge, J. W. Super-stereotypy I: enhancement of a complex movement sequence by systemic dopamine D1 agonists. Synapse 37, 194-204 (2000).
    • (2000) Synapse , vol.37 , pp. 194-204
    • Berridge, K.C.1    Aldridge, J.W.2
  • 64
    • 77649237815 scopus 로고    scopus 로고
    • Dopamine receptor modulation of repetitive grooming actions in the rat: Potential relevance for tourette syndrome
    • Taylor, J. L., Rajbhandari, A. K., Berridge, K. C. & Aldridge, J. W. Dopamine receptor modulation of repetitive grooming actions in the rat: potential relevance for Tourette syndrome. Brain Res. 1322, 92-101 (2010).
    • (2010) Brain Res , vol.1322 , pp. 92-101
    • Taylor, J.L.1    Rajbhandari, A.K.2    Berridge, K.C.3    Aldridge, J.W.4
  • 65
    • 84946501370 scopus 로고    scopus 로고
    • Evidence against dopamine d1/d2 receptor heteromers
    • Frederick, A. L. et al. Evidence against dopamine D1/D2 receptor heteromers. Mol. Psychiatry 20, 1373-1385 (2015).
    • (2015) Mol. Psychiatry , vol.20 , pp. 1373-1385
    • Frederick, A.L.1
  • 66
    • 0011798071 scopus 로고
    • Histochemically distinct compartments in the striatum of human, monkeys, and cat demonstrated by acetylthiocholinesterase staining
    • Graybiel, A. M. & Ragsdale, C. W. Jr. Histochemically distinct compartments in the striatum of human, monkeys, and cat demonstrated by acetylthiocholinesterase staining. Proc. Natl Acad. Sci. USA 75, 5723-5726 (1978).
    • (1978) Proc. Natl Acad. Sci. USA , vol.75 , pp. 5723-5726
    • Graybiel, A.M.1    Ragsdale, C.W.2
  • 67
    • 84859152259 scopus 로고    scopus 로고
    • Basal ganglia disorders associated with imbalances in the striatal striosome and matrix compartments
    • Crittenden, J. R. & Graybiel, A. M. Basal ganglia disorders associated with imbalances in the striatal striosome and matrix compartments. Front. Neuroanat. 5, 59 (2011).
    • (2011) Front. Neuroanat , vol.5 , pp. 59
    • Crittenden, J.R.1    Graybiel, A.M.2
  • 68
    • 84907459396 scopus 로고    scopus 로고
    • Striatal circuits, habits, and implications for obsessive-compulsive disorder
    • An excellent summary of striatal mechanisms in the formation of normal and pathological habits, with a particular reference to the pathogenesis of OCD
    • Burguiere, E., Monteiro, P., Mallet, L., Feng, G. & Graybiel, A. M. Striatal circuits, habits, and implications for obsessive-compulsive disorder. Curr. Opin. Neurobiol. 30, 59-65 (2015). An excellent summary of striatal mechanisms in the formation of normal and pathological habits, with a particular reference to the pathogenesis of OCD.
    • (2015) Curr. Opin. Neurobiol , vol.30 , pp. 59-65
    • Burguiere, E.1    Monteiro, P.2    Mallet, L.3    Feng, G.4    Graybiel, A.M.5
  • 69
    • 0034070315 scopus 로고    scopus 로고
    • Patterns of gene expression and behavior induced by chronic dopamine treatments
    • Canales, J. J. & Graybiel, A. M. Patterns of gene expression and behavior induced by chronic dopamine treatments. Ann. Neurol. 47, S53-S59 (2000).
    • (2000) Ann. Neurol , vol.47 , pp. S53-S59
    • Canales, J.J.1    Graybiel, A.M.2
  • 70
    • 4444273612 scopus 로고    scopus 로고
    • Repetitive behaviors in monkeys are linked to specific striatal activation patterns
    • Saka, E., Goodrich, C., Harlan, P., Madras, B. K. & Graybiel, A. M. Repetitive behaviors in monkeys are linked to specific striatal activation patterns. J. Neurosci. 24, 7557-7565 (2004).
    • (2004) J. Neurosci , vol.24 , pp. 7557-7565
    • Saka, E.1    Goodrich, C.2    Harlan, P.3    Madras, B.K.4    Graybiel, A.M.5
  • 72
    • 30344483615 scopus 로고    scopus 로고
    • Repeated subchronic exposure to phencyclidine elicits excessive atypical grooming in rats
    • Audet, M. C., Goulet, S. & Dore, F. Y. Repeated subchronic exposure to phencyclidine elicits excessive atypical grooming in rats. Behav. Brain Res. 167, 103-110 (2006).
    • (2006) Behav. Brain Res , vol.167 , pp. 103-110
    • Audet, M.C.1    Goulet, S.2    Dore, F.Y.3
  • 74
    • 0141924392 scopus 로고    scopus 로고
    • Effects of nra0045, a novel potent antagonist at dopamine d4, 5-ht2a, and ?1 adrenaline receptors, and nra0160, a selective d4 receptor antagonist, on phencyclidine-induced behavior and glutamate release in rats
    • Abekawa, T., Honda, M., Ito, K. & Koyama, T. Effects of NRA0045, a novel potent antagonist at dopamine D4, 5-HT2A, and ?1 adrenaline receptors, and NRA0160, a selective D4 receptor antagonist, on phencyclidine-induced behavior and glutamate release in rats. Psychopharmacology (Berl.) 169, 247-256 (2003).
    • (2003) Psychopharmacology (Berl , vol.169 , pp. 247-256
    • Abekawa, T.1    Honda, M.2    Ito, K.3    Koyama, T.4
  • 75
    • 0021752408 scopus 로고
    • An assessment of the spontaneous activity of rats administered morphine, phencyclidine, or nicotine using automated and observational methods
    • Iwamoto, E. T. An assessment of the spontaneous activity of rats administered morphine, phencyclidine, or nicotine using automated and observational methods. Psychopharmacology (Berl.) 84, 374-382 (1984).
    • (1984) Psychopharmacology (Berl , vol.84 , pp. 374-382
    • Iwamoto, E.T.1
  • 76
    • 84860837742 scopus 로고    scopus 로고
    • Anxiolytic effect of clonazepam in female rats: Grooming microstructure and elevated plus maze tests
    • Nin, M. S. et al. Anxiolytic effect of clonazepam in female rats: grooming microstructure and elevated plus maze tests. Eur. J. Pharmacol. 684, 95-101 (2012).
    • (2012) Eur. J. Pharmacol , vol.684 , pp. 95-101
    • Nin, M.S.1
  • 78
    • 0019861149 scopus 로고
    • Benzodiazepines decrease grooming in response to novelty but not acth or ?-endorphin
    • Dunn, A. J., Guild, A. L., Kramarcy, N. R. & Ware, M. D. Benzodiazepines decrease grooming in response to novelty but not ACTH or ?-endorphin. Pharmacol. Biochem. Behav. 15, 605-608 (1981).
    • (1981) Pharmacol. Biochem. Behav , vol.15 , pp. 605-608
    • Dunn, A.J.1    Guild, A.L.2    Kramarcy, N.R.3    Ware, M.D.4
  • 79
    • 0030439842 scopus 로고    scopus 로고
    • Role of gaba in memory and anxiety depress
    • Kalueff, A. & Nutt, D. J. Role of GABA in memory and anxiety. Depress. Anxiety 4, 100-110 (1996).
    • (1996) Anxiety , vol.4 , pp. 100-110
    • Kalueff, A.1    Nutt, D.J.2
  • 80
    • 0028340012 scopus 로고
    • Clonazepam as an augmenting agent in the treatment of childhood-onset obsessive-compulsive disorder
    • Leonard, H. L. et al. Clonazepam as an augmenting agent in the treatment of childhood-onset obsessive-compulsive disorder. J. Am. Acad. Child Adolesc. Psychiatry 33, 792-794 (1994).
    • (1994) J. Am. Acad. Child Adolesc. Psychiatry , vol.33 , pp. 792-794
    • Leonard, H.L.1
  • 81
    • 84864354308 scopus 로고    scopus 로고
    • Inactivation of the bed nucleus of the stria terminalis suppresses the innate fear responses of rats induced by the odor of cat urine
    • Xu, H. Y. et al. Inactivation of the bed nucleus of the stria terminalis suppresses the innate fear responses of rats induced by the odor of cat urine. Neuroscience 221, 21-27 (2012).
    • (2012) Neuroscience , vol.221 , pp. 21-27
    • Xu, H.Y.1
  • 82
    • 77249163194 scopus 로고    scopus 로고
    • The effects of chronic social defeat stress on mouse self-grooming behavior and its patterning
    • Denmark, A. et al. The effects of chronic social defeat stress on mouse self-grooming behavior and its patterning. Behav. Brain Res. 208, 553-559 (2010).
    • (2010) Behav. Brain Res , vol.208 , pp. 553-559
    • Denmark, A.1
  • 83
    • 84867013242 scopus 로고    scopus 로고
    • The effect of intra-nucleus accumbens administration of allopregnanolone on ? and ?2 gabaa receptor subunit mRNA expression in the hippocampus and on depressive-like and grooming behaviors in rats
    • Nin, M. S. et al. The effect of intra-nucleus accumbens administration of allopregnanolone on ? and ?2 GABAA receptor subunit mRNA expression in the hippocampus and on depressive-like and grooming behaviors in rats. Pharmacol. Biochem. Behav. 103, 359-366 (2012).
    • (2012) Pharmacol. Biochem. Behav , vol.103 , pp. 359-366
    • Nin, M.S.1
  • 84
    • 0025972270 scopus 로고
    • Alpha msh-induced excessive grooming behavior involves a gabaergic mechanism
    • De Barioglio, S. R., Lezcano, N. & Celis, M. E. Alpha MSH-induced excessive grooming behavior involves a GABAergic mechanism. Peptides 12, 203-205 (1991).
    • (1991) Peptides , vol.12 , pp. 203-205
    • De Barioglio, S.R.1    Lezcano, N.2    Celis, M.E.3
  • 85
    • 84939956304 scopus 로고    scopus 로고
    • Astroglial glutamate transporter deficiency increases synaptic excitability and leads to pathological repetitive behaviors in mice
    • Aida, T. et al. Astroglial glutamate transporter deficiency increases synaptic excitability and leads to pathological repetitive behaviors in mice. Neuropsychopharmacology 40, 1569-1579 (2015).
    • (2015) Neuropsychopharmacology , vol.40 , pp. 1569-1579
    • Aida, T.1
  • 87
    • 84898752877 scopus 로고    scopus 로고
    • The nimh research domain criteria (rdoc) project: Precision medicine for psychiatry
    • Insel, T. R. The NIMH Research Domain Criteria (RDoC) Project: precision medicine for psychiatry. Am. J. Psychiatry 171, 395-397 (2014).
    • (2014) Am. J. Psychiatry , vol.171 , pp. 395-397
    • Insel, T.R.1
  • 88
    • 84886043405 scopus 로고    scopus 로고
    • Dsm-5 and rdoc: Progress in psychiatry research?
    • Casey, B. J. et al. DSM-5 and RDoC: progress in psychiatry research? Nat. Rev. Neurosci. 14, 810-814 (2013).
    • (2013) Nat. Rev. Neurosci , vol.14 , pp. 810-814
    • Casey, B.J.1
  • 89
    • 84860678815 scopus 로고    scopus 로고
    • Reduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent shank3 null mutant mice
    • Yang, M. et al. Reduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent Shank3 null mutant mice. J. Neurosci. 32, 6525-6541 (2012).
    • (2012) J. Neurosci , vol.32 , pp. 6525-6541
    • Yang, M.1
  • 90
    • 76749128438 scopus 로고    scopus 로고
    • Repetitive self-grooming behavior in the btbr mouse model of autism is blocked by the mglur5 antagonist mpep
    • Silverman, J. L., Tolu, S. S., Barkan, C. L. & Crawley, J. N. Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP. Neuropsychopharmacology 35, 976-989 (2010).
    • (2010) Neuropsychopharmacology , vol.35 , pp. 976-989
    • Silverman, J.L.1    Tolu, S.S.2    Barkan, C.L.3    Crawley, J.N.4
  • 91
    • 84896732337 scopus 로고    scopus 로고
    • Assessing behavioural and cognitive domains of autism spectrum disorders in rodents: Current status and future perspectives
    • Kas, M. J. et al. Assessing behavioural and cognitive domains of autism spectrum disorders in rodents: current status and future perspectives. Psychopharmacology (Berl.) 231, 1125-1146 (2014).
    • (2014) Psychopharmacology (Berl , vol.231 , pp. 1125-1146
    • Kas, M.J.1
  • 92
    • 0003472502 scopus 로고    scopus 로고
    • American Psychiatric Association 5th edn American Psychiatric Association
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders 5th edn (American Psychiatric Association, 2013).
    • (2013) Diagnostic and Statistical Manual of Mental Disorders
  • 93
    • 84903763038 scopus 로고    scopus 로고
    • The promising trajectory of autism therapeutics discovery
    • Silverman, J. L. & Crawley, J. N. The promising trajectory of autism therapeutics discovery. Drug Discov. Today 19, 838-844 (2014).
    • (2014) Drug Discov. Today , vol.19 , pp. 838-844
    • Silverman, J.L.1    Crawley, J.N.2
  • 94
    • 79951782035 scopus 로고    scopus 로고
    • Motor and cognitive stereotypies in the btbr t+tf/j mouse model of autism
    • Pearson, B. L. et al. Motor and cognitive stereotypies in the BTBR T+tf/J mouse model of autism. Genes Brain Behav. 10, 228-235 (2011).
    • (2011) Genes Brain Behav , vol.10 , pp. 228-235
    • Pearson, B.L.1
  • 95
    • 84892459358 scopus 로고    scopus 로고
    • Validation and implementation of a novel high-throughput behavioral phenotyping instrument for mice
    • Brodkin, J. et al. Validation and implementation of a novel high-throughput behavioral phenotyping instrument for mice. J. Neurosci. Methods 224, 48-57 (2014).
    • (2014) J. Neurosci. Methods , vol.224 , pp. 48-57
    • Brodkin, J.1
  • 96
    • 79951562741 scopus 로고    scopus 로고
    • Social peers rescue autism-relevant sociability deficits in adolescent mice
    • Yang, M., Perry, K., Weber, M. D., Katz, A. M. & Crawley, J. N. Social peers rescue autism-relevant sociability deficits in adolescent mice. Autism Res. 4, 17-27 (2011).
    • (2011) Autism Res , vol.4 , pp. 17-27
    • Yang, M.1    Perry, K.2    Weber, M.D.3    Katz, A.M.4    Crawley, J.N.5
  • 97
    • 77953150437 scopus 로고    scopus 로고
    • Cholinergic abnormalities in autism: Is there a rationale for selective nicotinic agonist interventions? Clin
    • Deutsch, S. I., Urbano, M. R., Neumann, S. A., Burket, J. A. & Katz, E. Cholinergic abnormalities in autism: is there a rationale for selective nicotinic agonist interventions? Clin. Neuropharmacol. 33, 114-120 (2010).
    • (2010) Neuropharmacol , vol.33 , pp. 114-120
    • Deutsch, S.I.1    Urbano, M.R.2    Neumann, S.A.3    Burket, J.A.4    Katz, E.5
  • 98
    • 0034946403 scopus 로고    scopus 로고
    • Cholinergic activity in autism: Abnormalities in the cerebral cortex and basal forebrain
    • Perry, E. K. et al. Cholinergic activity in autism: abnormalities in the cerebral cortex and basal forebrain. Am. J. Psychiatry 158, 1058-1066 (2001).
    • (2001) Am. J. Psychiatry , vol.158 , pp. 1058-1066
    • Perry, E.K.1
  • 99
    • 84941416336 scopus 로고    scopus 로고
    • Reduction of aggressive episodes after repeated transdermal nicotine administration in a hospitalized adolescent with autism spectrum disorder
    • Van Schalkwyk, G. I. et al. Reduction of aggressive episodes after repeated transdermal nicotine administration in a hospitalized adolescent with autism spectrum disorder. J. Autism Dev. Disord. 45, 3061-3066 (2015).
    • (2015) J. Autism Dev. Disord , vol.45 , pp. 3061-3066
    • Van Schalkwyk, G.I.1
  • 100
    • 84894075773 scopus 로고    scopus 로고
    • Acetylcholine elevation relieves cognitive rigidity and social deficiency in a mouse model of autism
    • Karvat, G. & Kimchi, T. Acetylcholine elevation relieves cognitive rigidity and social deficiency in a mouse model of autism. Neuropsychopharmacology 39, 831-840 (2014).
    • (2014) Neuropsychopharmacology , vol.39 , pp. 831-840
    • Karvat, G.1    Kimchi, T.2
  • 101
    • 84860358233 scopus 로고    scopus 로고
    • Negative allosteric modulation of the mglur5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism
    • Silverman, J. L. et al. Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism. Sci. Transl Med. 4, 131ra51 (2012).
    • (2012) Sci. Transl Med , vol.4 , pp. 131ra51
    • Silverman, J.L.1
  • 102
    • 84878804982 scopus 로고    scopus 로고
    • D-cycloserine improves sociability in the btbr t+ itpr3tf/j mouse model of autism spectrum disorders with altered ras/raf/erk1/2 signaling
    • Burket, J. A., Benson, A. D., Tang, A. H. & Deutsch, S. I. D-Cycloserine improves sociability in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders with altered Ras/Raf/ERK1/2 signaling. Brain Res. Bull. 96, 62-70 (2013).
    • (2013) Brain Res. Bull , vol.96 , pp. 62-70
    • Burket, J.A.1    Benson, A.D.2    Tang, A.H.3    Deutsch, S.I.4
  • 103
    • 84901333522 scopus 로고    scopus 로고
    • A trial of d-cycloserine to treat stereotypies in older adolescents and young adults with autism spectrum disorder
    • Urbano, M. et al. A trial of D-cycloserine to treat stereotypies in older adolescents and young adults with autism spectrum disorder. Clin. Neuropharmacol. 37, 69-72 (2014).
    • (2014) Clin. Neuropharmacol , vol.37 , pp. 69-72
    • Urbano, M.1
  • 104
    • 7444237570 scopus 로고    scopus 로고
    • A pilot study of d-cycloserine in subjects with autistic disorder
    • Posey, D. J. et al. A pilot study of D-cycloserine in subjects with autistic disorder. Am. J. Psychiatry 161, 2115-2117 (2004).
    • (2004) Am. J. Psychiatry , vol.161 , pp. 2115-2117
    • Posey, D.J.1
  • 105
    • 84861630491 scopus 로고    scopus 로고
    • Shedding light on brain circuits
    • Insel, T. R. & Freund, M. Shedding light on brain circuits. Biol. Psychiatry 71, 1028-1029 (2012).
    • (2012) Biol. Psychiatry , vol.71 , pp. 1028-1029
    • Insel, T.R.1    Freund, M.2
  • 106
    • 84896713648 scopus 로고    scopus 로고
    • Advancing the discovery of medications for autism spectrum disorder using new technologies to reveal social brain circuitry in rodents
    • Kas, M. J., Modi, M. E., Saxe, M. D. & Smith, D. G. Advancing the discovery of medications for autism spectrum disorder using new technologies to reveal social brain circuitry in rodents. Psychopharmacolology (Berl.) 231, 1147-1165 (2014).
    • (2014) Psychopharmacolology (Berl , vol.231 , pp. 1147-1165
    • Kas, M.J.1    Modi, M.E.2    Saxe, M.D.3    Smith, D.G.4
  • 107
    • 84922229342 scopus 로고    scopus 로고
    • Clustering autism: Using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity
    • Ellegood, J. et al. Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity. Mol. Psychiatry 20, 118-125 (2015).
    • (2015) Mol. Psychiatry , vol.20 , pp. 118-125
    • Ellegood, J.1
  • 108
    • 84901286741 scopus 로고    scopus 로고
    • Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome
    • Portmann, T. et al. Behavioral abnormalities and circuit defects in the basal ganglia of a mouse model of 16p11.2 deletion syndrome. Cell Rep. 7, 1077-1092 (2014).
    • (2014) Cell Rep , vol.7 , pp. 1077-1092
    • Portmann, T.1
  • 109
    • 84896870880 scopus 로고    scopus 로고
    • Behavioral signatures related to genetic disorders in autism
    • Bruining, H. et al. Behavioral signatures related to genetic disorders in autism. Mol. Autism 5, 11 (2014).
    • (2014) Mol. Autism , vol.5 , pp. 11
    • Bruining, H.1
  • 110
    • 84891902104 scopus 로고    scopus 로고
    • The emerging role of shank genes in neuropsychiatric disorders
    • Guilmatre, A., Huguet, G., Delorme, R. & Bourgeron, T. The emerging role of SHANK genes in neuropsychiatric disorders. Dev. Neurobiol. 74, 113-122 (2014).
    • (2014) Dev. Neurobiol , vol.74 , pp. 113-122
    • Guilmatre, A.1    Huguet, G.2    Delorme, R.3    Bourgeron, T.4
  • 111
    • 84991265048 scopus 로고    scopus 로고
    • Translational neurobiology in shank mutant mice - Model systems for neuropsychiatric disorders
    • Schmeisser, M. J. Translational neurobiology in Shank mutant mice - model systems for neuropsychiatric disorders. Ann. Anat. 200, 115-117 (2015).
    • (2015) Ann. Anat , vol.200 , pp. 115-117
    • Schmeisser, M.J.1
  • 112
    • 84862297282 scopus 로고    scopus 로고
    • Autistic-like social behaviour in shank2-mutant mice improved by restoring nmda receptor function
    • Won, H. et al. Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. Nature 486, 261-265 (2012).
    • (2012) Nature , vol.486 , pp. 261-265
    • Won, H.1
  • 113
    • 79955536349 scopus 로고    scopus 로고
    • Shank3 mutant mice display autistic-like behaviours and striatal dysfunction
    • Peca, J. et al. Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. Nature 472, 437-442 (2011).
    • (2011) Nature , vol.472 , pp. 437-442
    • Peca, J.1
  • 114
    • 79960111638 scopus 로고    scopus 로고
    • Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of shank3
    • Wang, X. et al. Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3. Hum. Mol. Genet. 20, 3093-3108 (2011).
    • (2011) Hum. Mol. Genet , vol.20 , pp. 3093-3108
    • Wang, X.1
  • 115
    • 84908671161 scopus 로고    scopus 로고
    • Repetitive grooming and sensorimotor abnormalities in an ephrin-A knockout model for autism spectrum disorders
    • Wurzman, R., Forcelli, P. A., Griffey, C. J. & Kromer, L. F. Repetitive grooming and sensorimotor abnormalities in an ephrin-A knockout model for autism spectrum disorders. Behav. Brain Res. 278, 115-128 (2014).
    • (2014) Behav. Brain Res , vol.278 , pp. 115-128
    • Wurzman, R.1    Forcelli, P.A.2    Griffey, C.J.3    Kromer, L.F.4
  • 116
    • 84893182133 scopus 로고    scopus 로고
    • Decoding the contribution of dopaminergic genes and pathways to autism spectrum disorder (asd
    • Nguyen, M. et al. Decoding the contribution of dopaminergic genes and pathways to autism spectrum disorder (ASD). Neurochem. Int. 66, 15-26 (2014).
    • (2014) Neurochem. Int , vol.66 , pp. 15-26
    • Nguyen, M.1
  • 118
    • 84903770145 scopus 로고    scopus 로고
    • Loss of glutamic acid decarboxylase (gad67) in gpr88-expressing neurons induces learning and social behavior deficits in mice
    • Zhang, K., Hill, K., Labak, S., Blatt, G. J. & Soghomonian, J. J. Loss of glutamic acid decarboxylase (Gad67) in Gpr88-expressing neurons induces learning and social behavior deficits in mice. Neuroscience 275, 238-247 (2014).
    • (2014) Neuroscience , vol.275 , pp. 238-247
    • Zhang, K.1    Hill, K.2    Labak, S.3    Blatt, G.J.4    Soghomonian, J.J.5
  • 119
    • 84902164648 scopus 로고    scopus 로고
    • Transcriptional consequences of 16p11.2 deletion and duplication in mouse cortex and multiplex autism families
    • Blumenthal, I. et al. Transcriptional consequences of 16p11.2 deletion and duplication in mouse cortex and multiplex autism families. Am. J. Hum. Genet. 94, 870-883 (2014).
    • (2014) Am. J. Hum. Genet , vol.94 , pp. 870-883
    • Blumenthal, I.1
  • 120
    • 84961348340 scopus 로고    scopus 로고
    • The 16p11.2 locus modulates brain structures common to autism, schizophrenia and obesity
    • Maillard, A. M. et al. The 16p11.2 locus modulates brain structures common to autism, schizophrenia and obesity. Mol. Psychiatry 20, 140-147 (2015).
    • (2015) Mol. Psychiatry , vol.20 , pp. 140-147
    • Maillard, A.M.1
  • 121
    • 84922249864 scopus 로고    scopus 로고
    • The role of parental cognitive, behavioral, and motor profiles in clinical variability in individuals with chromosome 16p11.2 deletions
    • Moreno-De-Luca, A. et al. The role of parental cognitive, behavioral, and motor profiles in clinical variability in individuals with chromosome 16p11.2 deletions. JAMA Psychiatry 72, 119-126 (2015).
    • (2015) JAMA Psychiatry , vol.72 , pp. 119-126
    • Moreno-De-Luca, A.1
  • 122
    • 67649422311 scopus 로고    scopus 로고
    • Sapap3 and pathological grooming in humans: Results from the ocd collaborative genetics study
    • Bienvenu, O. J. et al. Sapap3 and pathological grooming in humans: results from the OCD collaborative genetics study. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B, 710-720 (2009).
    • (2009) Am. J. Med. Genet. B Neuropsychiatr. Genet , vol.150 B , pp. 710-720
    • Bienvenu, O.J.1
  • 123
    • 0033636505 scopus 로고    scopus 로고
    • Toward a neurobiology of obsessive-compulsive disorder
    • Graybiel, A. M. & Rauch, S. L. Toward a neurobiology of obsessive-compulsive disorder. Neuron 28, 343-347 (2000).
    • (2000) Neuron , vol.28 , pp. 343-347
    • Graybiel, A.M.1    Rauch, S.L.2
  • 124
    • 84898953190 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder
    • Bokor, G. & Anderson, P. D. Obsessive-compulsive disorder. J. Pharm. Pract. 27, 116-130 (2014).
    • (2014) J. Pharm. Pract , vol.27 , pp. 116-130
    • Bokor, G.1    Anderson, P.D.2
  • 125
    • 77955482780 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder and its related disorders: A reappraisal of obsessive-compulsive spectrum concepts
    • Murphy, D. L., Timpano, K. R., Wheaton, M. G., Greenberg, B. D. & Miguel, E. C. Obsessive-compulsive disorder and its related disorders: a reappraisal of obsessive-compulsive spectrum concepts. Dialogues Clin. Neurosci. 12, 131-148 (2010).
    • (2010) Dialogues Clin. Neurosci , vol.12 , pp. 131-148
    • Murphy, D.L.1    Timpano, K.R.2    Wheaton, M.G.3    Greenberg, B.D.4    Miguel, E.C.5
  • 127
    • 79952707004 scopus 로고    scopus 로고
    • Reverse-translational biomarker validation of abnormal repetitive behaviors in mice: An illustration of the 4p's modeling approach
    • Garner, J. P. et al. Reverse-translational biomarker validation of abnormal repetitive behaviors in mice: an illustration of the 4P's modeling approach. Behav. Brain Res. 219, 189-196 (2011).
    • (2011) Behav. Brain Res , vol.219 , pp. 189-196
    • Garner, J.P.1
  • 128
    • 2342471363 scopus 로고    scopus 로고
    • Barbering (fur and whisker trimming) by laboratory mice as a model of human trichotillomania and obsessive-compulsive spectrum disorders
    • Garner, J. P., Weisker, S. M., Dufour, B. & Mench, J. A. Barbering (fur and whisker trimming) by laboratory mice as a model of human trichotillomania and obsessive-compulsive spectrum disorders. Comp. Med. 54, 216-224 (2004).
    • (2004) Comp. Med , vol.54 , pp. 216-224
    • Garner, J.P.1    Weisker, S.M.2    Dufour, B.3    Mench, J.A.4
  • 129
    • 70849096543 scopus 로고    scopus 로고
    • The mouse who couldn't stop washing: Pathologic grooming in animals and humans
    • Feusner, J. D., Hembacher, E. & Phillips, K. A. The mouse who couldn't stop washing: pathologic grooming in animals and humans. CNS Spectr. 14, 503-513 (2009).
    • (2009) CNS Spectr , vol.14 , pp. 503-513
    • Feusner, J.D.1    Hembacher, E.2    Phillips, K.A.3
  • 130
    • 38649099407 scopus 로고    scopus 로고
    • Targeting the murine serotonin transporter: Insights into human neurobiology
    • Murphy, D. L. & Lesch, K. P. Targeting the murine serotonin transporter: insights into human neurobiology. Nat. Rev. Neurosci. 9, 85-96 (2008).
    • (2008) Nat. Rev. Neurosci , vol.9 , pp. 85-96
    • Murphy, D.L.1    Lesch, K.P.2
  • 131
    • 84867866203 scopus 로고    scopus 로고
    • Alterations in grooming activity and syntax in heterozygous sert and bdnf knockout mice: The utility of behavior-recognition tools to characterize mutant mouse phenotypes
    • Kyzar, E. J. et al. Alterations in grooming activity and syntax in heterozygous SERT and BDNF knockout mice: the utility of behavior-recognition tools to characterize mutant mouse phenotypes. Brain Res. Bull. 89, 168-176 (2012).
    • (2012) Brain Res. Bull , vol.89 , pp. 168-176
    • Kyzar, E.J.1
  • 132
    • 72449207509 scopus 로고    scopus 로고
    • Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes
    • Kalueff, A. V., Olivier, J. D., Nonkes, L. J. & Homberg, J. R. Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes. Neurosci. Biobehav. Rev. 34, 373-386 (2010).
    • (2010) Neurosci. Biobehav. Rev , vol.34 , pp. 373-386
    • Kalueff, A.V.1    Olivier, J.D.2    Nonkes, L.J.3    Homberg, J.R.4
  • 133
    • 84883552998 scopus 로고    scopus 로고
    • Common and rare alleles of the serotonin transporter gene, slc6a4, associated with tourette's disorder
    • Moya, P. R. et al. Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette's disorder. Mov. Disord. 28, 1263-1270 (2013).
    • (2013) Mov. Disord , vol.28 , pp. 1263-1270
    • Moya, P.R.1
  • 134
    • 53649090041 scopus 로고    scopus 로고
    • How the serotonin story is being rewritten by new gene-based discoveries principally related to slc6a4, the serotonin transporter gene, which functions to influence all cellular serotonin systems
    • Murphy, D. L. et al. How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. Neuropharmacology 55, 932-960 (2008).
    • (2008) Neuropharmacology , vol.55 , pp. 932-960
    • Murphy, D.L.1
  • 135
    • 39749154209 scopus 로고    scopus 로고
    • A novel, putative gain-of-function haplotype at slc6a4 associates with obsessive-compulsive disorder
    • Wendland, J. R. et al. A novel, putative gain-of-function haplotype at SLC6A4 associates with obsessive-compulsive disorder. Hum. Mol. Genet. 17, 717-723 (2008).
    • (2008) Hum. Mol. Genet , vol.17 , pp. 717-723
    • Wendland, J.R.1
  • 136
    • 78650510114 scopus 로고    scopus 로고
    • Association of slc6a4 variants with obsessive-compulsive disorder in a large multicenter us family study
    • Voyiaziakis, E. et al. Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study. Mol. Psychiatry 16, 108-120 (2011).
    • (2011) Mol. Psychiatry , vol.16 , pp. 108-120
    • Voyiaziakis, E.1
  • 137
    • 58049192995 scopus 로고    scopus 로고
    • Multiple rare sapap3 missense variants in trichotillomania and ocd
    • Zuchner, S. et al. Multiple rare SAPAP3 missense variants in trichotillomania and OCD. Mol. Psychiatry 14, 6-9 (2009).
    • (2009) Mol. Psychiatry , vol.14 , pp. 6-9
    • Zuchner, S.1
  • 138
    • 79551600821 scopus 로고    scopus 로고
    • Investigating sapap3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population
    • Boardman, L. et al. Investigating SAPAP3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population. Compr. Psychiatry 52, 181-187 (2011).
    • (2011) Compr. Psychiatry , vol.52 , pp. 181-187
    • Boardman, L.1
  • 139
    • 84897107762 scopus 로고    scopus 로고
    • Circuit-selective striatal synaptic dysfunction in the sapap3 knockout mouse model of obsessive-compulsive disorder
    • Wan, Y. et al. Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder. Biol. Psychiatry 75, 623-630 (2014).
    • (2014) Biol. Psychiatry , vol.75 , pp. 623-630
    • Wan, Y.1
  • 140
    • 84948456977 scopus 로고    scopus 로고
    • Learning from animal models of obsessive-compulsive disorder
    • Monteiro, P. & Feng, G. Learning from animal models of obsessive-compulsive disorder. Biol. Psychiatry 79, 7-16 (2016).
    • (2016) Biol. Psychiatry , vol.79 , pp. 7-16
    • Monteiro, P.1    Feng, G.2
  • 141
    • 84937974634 scopus 로고    scopus 로고
    • Dissecting ocd circuits: From animal models to targeted treatments
    • This recent review provides an excellent summary of circuits involved in OCD pathogenesis in preclinical and translational models
    • Ahmari, S. E. & Dougherty, D. D. Dissecting OCD circuits: from animal models to targeted treatments. Depress. Anxiety 32, 550-562 (2015). This recent review provides an excellent summary of circuits involved in OCD pathogenesis in preclinical and translational models.
    • (2015) Depress. Anxiety , vol.32 , pp. 550-562
    • Ahmari, S.E.1    Dougherty, D.D.2
  • 142
    • 84920191001 scopus 로고    scopus 로고
    • Cross-disorder genome-wide analyses suggest a complex genetic relationship between tourette's syndrome and ocd
    • Yu, D. et al. Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. Am. J. Psychiatry 172, 82-93 (2015).
    • (2015) Am. J. Psychiatry , vol.172 , pp. 82-93
    • Yu, D.1
  • 143
    • 80052384273 scopus 로고    scopus 로고
    • Neurobiology of tourette syndrome: Current status and need for further investigation
    • Felling, R. J. & Singer, H. S. Neurobiology of tourette syndrome: current status and need for further investigation. J. Neurosci. 31, 12387-12395 (2011).
    • (2011) J. Neurosci , vol.31 , pp. 12387-12395
    • Felling, R.J.1    Singer, H.S.2
  • 144
    • 79952243302 scopus 로고    scopus 로고
    • Family-based genetic association study of dlgap3 in tourette syndrome
    • Crane, J. et al. Family-based genetic association study of DLGAP3 in Tourette Syndrome. Am. J. Med. Genet. B Neuropsychiatr. Genet. 156B, 108-114 (2011).
    • (2011) Am. J. Med. Genet. B Neuropsychiatr. Genet , vol.156 B , pp. 108-114
    • Crane, J.1
  • 145
    • 84904976512 scopus 로고    scopus 로고
    • Copy number variation in obsessive-compulsive disorder and tourette syndrome: A cross-disorder study
    • McGrath, L. M. et al. Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study. J. Am. Acad. Child Adolesc. Psychiatry 53, 910-919 (2014).
    • (2014) J. Am. Acad. Child Adolesc. Psychiatry , vol.53 , pp. 910-919
    • McGrath, L.M.1
  • 146
    • 84887265151 scopus 로고    scopus 로고
    • Partitioning the heritability of tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture
    • Davis, L. K. et al. Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genet. 9, e1003864 (2013).
    • (2013) PLoS Genet , vol.9 , pp. e1003864
    • Davis, L.K.1
  • 147
    • 84886771410 scopus 로고    scopus 로고
    • Dopaminergic activity in tourette syndrome and obsessive-compulsive disorder
    • Denys, D. et al. Dopaminergic activity in Tourette syndrome and obsessive-compulsive disorder. Eur. Neuropsychopharmacol. 23, 1423-1431 (2013).
    • (2013) Eur. Neuropsychopharmacol , vol.23 , pp. 1423-1431
    • Denys, D.1
  • 148
    • 0031866675 scopus 로고    scopus 로고
    • Action sequencing is impaired in d1a-deficient mutant mice
    • Cromwell, H. C., Berridge, K. C., Drago, J. & Levine, M. S. Action sequencing is impaired in D1A-deficient mutant mice. Eur. J. Neurosci. 10, 2426-2432 (1998).
    • (1998) Eur. J. Neurosci , vol.10 , pp. 2426-2432
    • Cromwell, H.C.1    Berridge, K.C.2    Drago, J.3    Levine, M.S.4
  • 149
    • 0036342770 scopus 로고    scopus 로고
    • A transgenic model of comorbid tourette's syndrome and obsessive-compulsive disorder circuitry
    • Nordstrom, E. J. & Burton, F. H. A transgenic model of comorbid Tourette's syndrome and obsessive-compulsive disorder circuitry. Mol. Psychiatry 7, 617-625 (2002).
    • (2002) Mol. Psychiatry , vol.7 , pp. 617-625
    • Nordstrom, E.J.1    Burton, F.H.2
  • 150
    • 84927129275 scopus 로고    scopus 로고
    • Histidine decarboxylase knockout mice, a genetic model of tourette syndrome, show repetitive grooming after induced fear
    • Xu, M., Li, L., Ohtsu, H. & Pittenger, C. Histidine decarboxylase knockout mice, a genetic model of Tourette syndrome, show repetitive grooming after induced fear. Neurosci. Lett. 595, 50-53 (2015).
    • (2015) Neurosci. Lett , vol.595 , pp. 50-53
    • Xu, M.1    Li, L.2    Ohtsu, H.3    Pittenger, C.4
  • 151
    • 0029962959 scopus 로고    scopus 로고
    • Cell death in the midbrain of the murine mutation weaver
    • Roffler-Tarlov, S., Martin, B., Graybiel, A. M. & Kauer, J. S. Cell death in the midbrain of the murine mutation weaver. J. Neurosci. 16, 1819-1826 (1996).
    • (1996) J. Neurosci , vol.16 , pp. 1819-1826
    • Roffler-Tarlov, S.1    Martin, B.2    Graybiel, A.M.3    Kauer, J.S.4
  • 152
    • 0025261771 scopus 로고
    • Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. I. Gradients and compartments
    • Graybiel, A. M., Ohta, K. & Roffler-Tarlov, S. Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. I. Gradients and compartments. J. Neurosci. 10, 720-733 (1990).
    • (1990) J. Neurosci , vol.10 , pp. 720-733
    • Graybiel, A.M.1    Ohta, K.2    Roffler-Tarlov, S.3
  • 153
    • 0022980571 scopus 로고
    • Expression of the weaver gene in dopamine-containing neural systems is dose-dependent and affects both striatal and nonstriatal regions
    • Roffler-Tarlov, S. & Graybiel, A. M. Expression of the weaver gene in dopamine-containing neural systems is dose-dependent and affects both striatal and nonstriatal regions. J. Neurosci. 6, 3319-3330 (1986).
    • (1986) J. Neurosci , vol.6 , pp. 3319-3330
    • Roffler-Tarlov, S.1    Graybiel, A.M.2
  • 154
    • 0021245295 scopus 로고
    • Weaver mutation has differential effects on the dopamine-containing innervation of the limbic and nonlimbic striatum
    • Roffler-Tarlov, S. & Graybiel, A. M. Weaver mutation has differential effects on the dopamine-containing innervation of the limbic and nonlimbic striatum. Nature 307, 62-66 (1984).
    • (1984) Nature , vol.307 , pp. 62-66
    • Roffler-Tarlov, S.1    Graybiel, A.M.2
  • 155
    • 0029917484 scopus 로고    scopus 로고
    • Separation of activation and pattern in grooming development of weaver mice
    • Bolivar, V. J., Danilchuk, W. & Fentress, J. C. Separation of activation and pattern in grooming development of weaver mice. Behav. Brain Res. 75, 49-58 (1996).
    • (1996) Behav. Brain Res , vol.75 , pp. 49-58
    • Bolivar, V.J.1    Danilchuk, W.2    Fentress, J.C.3
  • 156
    • 0023337805 scopus 로고
    • Behavioral changes in acth-(1-24)-induced excessive grooming in aging rats
    • Spruijt, B. M., Welbergen, P., Brakkee, J. & Gispen, W. H. Behavioral changes in ACTH-(1-24)-induced excessive grooming in aging rats. Neurobiol. Aging 8, 265-270 (1987).
    • (1987) Neurobiol. Aging , vol.8 , pp. 265-270
    • Spruijt, B.M.1    Welbergen, P.2    Brakkee, J.3    Gispen, W.H.4
  • 157
    • 0023131397 scopus 로고
    • Effect of the chronic ingestion of chlorimipramine and desipramine on the hole board response to acute stresses in male rats
    • Rodriguez Echandia, E. L., Broitman, S. T. & Foscolo, M. R. Effect of the chronic ingestion of chlorimipramine and desipramine on the hole board response to acute stresses in male rats. Pharmacol. Biochem. Behav. 26, 207-210 (1987).
    • (1987) Pharmacol. Biochem. Behav , vol.26 , pp. 207-210
    • Rodriguez Echandia, E.L.1    Broitman, S.T.2    Foscolo, M.R.3
  • 158
    • 25144498551 scopus 로고    scopus 로고
    • Abnormal behavioral organization of grooming in mice lacking the Vitamin D receptor gene
    • Kalueff, A. V., Lou, Y. R., Laaksi, I. & Tuohimaa, P. Abnormal behavioral organization of grooming in mice lacking the vitamin D receptor gene. J. Neurogenet. 19, 1-24 (2005).
    • (2005) J. Neurogenet , vol.19 , pp. 1-24
    • Kalueff, A.V.1    Lou, Y.R.2    Laaksi, I.3    Tuohimaa, P.4
  • 159
    • 84888313593 scopus 로고    scopus 로고
    • Context-dependent differences in grooming behavior among the nih heterogeneous stock and the roman high-And low-Avoidance rats
    • Estanislau, C. et al. Context-dependent differences in grooming behavior among the NIH heterogeneous stock and the Roman high-And low-Avoidance rats. Neurosci. Res. 77, 187-201 (2013).
    • (2013) Neurosci. Res , vol.77 , pp. 187-201
    • Estanislau, C.1
  • 160
    • 84881018218 scopus 로고    scopus 로고
    • Behavioral characterization of a53t mice reveals early and late stage deficits related to Parkinson's disease
    • Paumier, K. L. et al. Behavioral characterization of A53T mice reveals early and late stage deficits related to Parkinson's disease. PLoS ONE 8, e70274 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e70274
    • Paumier, K.L.1
  • 161
    • 84879601960 scopus 로고    scopus 로고
    • The many faces of ?-synuclein mutations
    • Kasten, M. & Klein, C. The many faces of ?-synuclein mutations. Mov. Disord. 28, 697-701 (2013).
    • (2013) Mov. Disord , vol.28 , pp. 697-701
    • Kasten, M.1    Klein, C.2
  • 162
    • 33846917641 scopus 로고    scopus 로고
    • The power of automated high-resolution behavior analysis revealed by its application to mouse models of huntington's and prion diseases
    • Steele, A. D., Jackson, W. S., King, O. D. & Lindquist, S. The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases. Proc. Natl Acad. Sci. USA 104, 1983-1988 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 1983-1988
    • Steele, A.D.1    Jackson, W.S.2    King, O.D.3    Lindquist, S.4
  • 163
    • 0033614772 scopus 로고    scopus 로고
    • Transgenic mice expressing mutated full-length HD cdna: A paradigm for locomotor changes and selective neuronal loss in huntington's disease
    • Reddy, P. H. et al. Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease. Phil. Trans. R. Soc. Lond. B 354, 1035-1045 (1999).
    • (1999) Phil. Trans. R. Soc. Lond. B , vol.354 , pp. 1035-1045
    • Reddy, P.H.1
  • 164
    • 2942532898 scopus 로고    scopus 로고
    • Progressive behavioural changes in the spatial open-field in the quinolinic acid rat model of huntington's disease
    • Scattoni, M. L. et al. Progressive behavioural changes in the spatial open-field in the quinolinic acid rat model of Huntington's disease. Behav. Brain Res. 152, 375-383 (2004).
    • (2004) Behav. Brain Res , vol.152 , pp. 375-383
    • Scattoni, M.L.1
  • 165
    • 33846906945 scopus 로고    scopus 로고
    • Sex differences in behavior and striatal ascorbate release in the 140 cag knock-in mouse model of huntington's disease
    • Dorner, J. L., Miller, B. R., Barton, S. J., Brock, T. J. & Rebec, G. V. Sex differences in behavior and striatal ascorbate release in the 140 CAG knock-in mouse model of Huntington's disease. Behav. Brain Res. 178, 90-97 (2007).
    • (2007) Behav. Brain Res , vol.178 , pp. 90-97
    • Dorner, J.L.1    Miller, B.R.2    Barton, S.J.3    Brock, T.J.4    Rebec, G.V.5
  • 166
    • 79251570219 scopus 로고    scopus 로고
    • Differential electrophysiological changes in striatal output neurons in huntington's disease
    • Andre, V. M. et al. Differential electrophysiological changes in striatal output neurons in Huntington's disease. J. Neurosci. 31, 1170-1182 (2011).
    • (2011) J. Neurosci , vol.31 , pp. 1170-1182
    • Andre, V.M.1
  • 167
    • 0036074718 scopus 로고    scopus 로고
    • The role of dopamine in motor symptoms in the r6/2 transgenic mouse model of huntington's disease
    • Hickey, M. A., Reynolds, G. P. & Morton, A. J. The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease. J. Neurochem. 81, 46-59 (2002).
    • (2002) J. Neurochem , vol.81 , pp. 46-59
    • Hickey, M.A.1    Reynolds, G.P.2    Morton, A.J.3
  • 168
    • 57449090951 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the danish mutant form of human bri2
    • Vidal, R., Barbeito, A. G., Miravalle, L. & Ghetti, B. Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the Danish mutant form of human BRI2. Brain Pathol. 19, 58-68 (2009).
    • (2009) Brain Pathol , vol.19 , pp. 58-68
    • Vidal, R.1    Barbeito, A.G.2    Miravalle, L.3    Ghetti, B.4
  • 169
    • 84865980037 scopus 로고    scopus 로고
    • High-throughput screening of stem cell therapy for globoid cell leukodystrophy using automated neurophenotyping of twitcher mice
    • Scruggs, B. A. et al. High-throughput screening of stem cell therapy for globoid cell leukodystrophy using automated neurophenotyping of twitcher mice. Behav. Brain Res. 236, 35-47 (2013).
    • (2013) Behav. Brain Res , vol.236 , pp. 35-47
    • Scruggs, B.A.1
  • 170
    • 33645844263 scopus 로고    scopus 로고
    • Neonatal administration of n-Acetyl-l-Aspartyl-l-glutamate induces early neurodegeneration in hippocampus and alters behaviour in young adult rats
    • Bubenikova-Valesova, V. & Balcar, V. J., Tejkalova, H., Langmeier, M. & St'astny, F. Neonatal administration of N-Acetyl-L-Aspartyl-L-glutamate induces early neurodegeneration in hippocampus and alters behaviour in young adult rats. Neurochem. Int. 48, 515-522 (2006).
    • (2006) Neurochem. Int , vol.48 , pp. 515-522
    • Bubenikova-Valesova, V.1    Balcar, V.J.2    Tejkalova, H.3    Langmeier, M.4    St'Astny, F.5
  • 171
    • 26444619475 scopus 로고    scopus 로고
    • Profound ataxia in complexin i knockout mice masks a complex phenotype that includes exploratory and habituation deficits
    • Glynn, D., Drew, C. J., Reim, K., Brose, N. & Morton, A. J. Profound ataxia in complexin I knockout mice masks a complex phenotype that includes exploratory and habituation deficits. Hum. Mol. Genet. 14, 2369-2385 (2005).
    • (2005) Hum. Mol. Genet , vol.14 , pp. 2369-2385
    • Glynn, D.1    Drew, C.J.2    Reim, K.3    Brose, N.4    Morton, A.J.5
  • 172
    • 67349151319 scopus 로고    scopus 로고
    • Mouse models of huntington's disease and methodological considerations for therapeutic trials
    • Ferrante, R. J. Mouse models of Huntington's disease and methodological considerations for therapeutic trials. Biochim. Biophys. Acta 1792, 506-520 (2009).
    • (2009) Biochim. Biophys. Acta , vol.1792 , pp. 506-520
    • Ferrante, R.J.1
  • 173
    • 79957441385 scopus 로고    scopus 로고
    • Discovering imaging endophenotypes for major depression
    • Hasler, G. & Northoff, G. Discovering imaging endophenotypes for major depression. Mol. Psychiatry 16, 604-619 (2011).
    • (2011) Mol. Psychiatry , vol.16 , pp. 604-619
    • Hasler, G.1    Northoff, G.2
  • 174
    • 46849122212 scopus 로고    scopus 로고
    • Structural cerebral variations as useful endophenotypes in schizophrenia: Do they help construct "extended endophenotypes"?
    • Prasad, K. M. & Keshavan, M. S. Structural cerebral variations as useful endophenotypes in schizophrenia: do they help construct "extended endophenotypes"? Schizophr. Bull. 34, 774-790 (2008).
    • (2008) Schizophr. Bull , vol.34 , pp. 774-790
    • Prasad, K.M.1    Keshavan, M.S.2
  • 175
    • 84885761119 scopus 로고    scopus 로고
    • Neuroimaging evidence of major morpho-Anatomical and functional abnormalities in the btbr t+tf/j mouse model of autism
    • Dodero, L. et al. Neuroimaging evidence of major morpho-Anatomical and functional abnormalities in the BTBR T+TF/J mouse model of autism. PLoS ONE 8, e76655 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e76655
    • Dodero, L.1
  • 176
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • Gottesman, I. I. & Gould, T. D. The endophenotype concept in psychiatry: etymology and strategic intentions. Am. J. Psychiatry 160, 636-645 (2003).
    • (2003) Am. J. Psychiatry , vol.160 , pp. 636-645
    • Gottesman, I.I.1    Gould, T.D.2
  • 178
    • 0033797277 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder and comorbid anxiety problems in a national anxiety screening sample
    • Welkowitz, L. A., Struening, E. L., Pittman, J., Guardino, M. & Welkowitz, J. Obsessive-compulsive disorder and comorbid anxiety problems in a national anxiety screening sample. J. Anxiety Disord. 14, 471-482 (2000).
    • (2000) J. Anxiety Disord , vol.14 , pp. 471-482
    • Welkowitz, L.A.1    Struening, E.L.2    Pittman, J.3    Guardino, M.4    Welkowitz, J.5
  • 179
    • 0032843204 scopus 로고    scopus 로고
    • Anxiety in a transgenic mouse model of cortical-limbic neuro-potentiated compulsive behavior
    • McGrath, M. J., Campbell, K. M., Veldman, M. B. & Burton, F. H. Anxiety in a transgenic mouse model of cortical-limbic neuro-potentiated compulsive behavior. Behav. Pharmacol. 10, 435-443 (1999).
    • (1999) Behav. Pharmacol , vol.10 , pp. 435-443
    • McGrath, M.J.1    Campbell, K.M.2    Veldman, M.B.3    Burton, F.H.4
  • 180
    • 0347284309 scopus 로고    scopus 로고
    • The nucleus accumbens: A target for deep brain stimulation in obsessive-compulsive-And anxiety-disorders
    • Sturm, V. et al. The nucleus accumbens: a target for deep brain stimulation in obsessive-compulsive-And anxiety-disorders. J. Chem. Neuroanat. 26, 293-299 (2003).
    • (2003) J. Chem. Neuroanat , vol.26 , pp. 293-299
    • Sturm, V.1
  • 181
    • 38949186029 scopus 로고    scopus 로고
    • Striatal dopamine d2 receptor availability in ocd with and without comorbid social anxiety disorder: Preliminary findings
    • Schneier, F. R. et al. Striatal dopamine D2 receptor availability in OCD with and without comorbid social anxiety disorder: preliminary findings. Depress. Anxiety 25, 1-7 (2008).
    • (2008) Depress. Anxiety , vol.25 , pp. 1-7
    • Schneier, F.R.1
  • 182
    • 84910077437 scopus 로고    scopus 로고
    • Modeling neuropsychiatric spectra to empower translational biological psychiatry
    • Kalueff, A. V. & Stewart, A. M. Modeling neuropsychiatric spectra to empower translational biological psychiatry. Behav. Brain Res. 276, 1-7 (2015).
    • (2015) Behav. Brain Res , vol.276 , pp. 1-7
    • Kalueff, A.V.1    Stewart, A.M.2
  • 183
    • 58149337611 scopus 로고    scopus 로고
    • Refining psychiatric genetics: From 'mouse psychiatry' to understanding complex human disorders
    • Laporte, J. L., Ren-Patterson, R. F., Murphy, D. L. & Kalueff, A. V. Refining psychiatric genetics: from 'mouse psychiatry' to understanding complex human disorders. Behav. Pharmacol. 19, 377-384 (2008).
    • (2008) Behav. Pharmacol , vol.19 , pp. 377-384
    • Laporte, J.L.1    Ren-Patterson, R.F.2    Murphy, D.L.3    Kalueff, A.V.4
  • 184
    • 84910068874 scopus 로고    scopus 로고
    • Developing better and more valid animal models of brain disorders
    • Stewart, A. M. & Kalueff, A. V. Developing better and more valid animal models of brain disorders. Behav. Brain Res. 276, 28-31 (2015).
    • (2015) Behav. Brain Res , vol.276 , pp. 28-31
    • Stewart, A.M.1    Kalueff, A.V.2
  • 185
    • 84922287338 scopus 로고    scopus 로고
    • Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of tourette syndrome
    • Xu, M. et al. Targeted ablation of cholinergic interneurons in the dorsolateral striatum produces behavioral manifestations of Tourette syndrome. Proc. Natl Acad. Sci. USA 112, 893-898 (2015).
    • (2015) Proc. Natl Acad. Sci. USA , vol.112 , pp. 893-898
    • Xu, M.1
  • 186
    • 0033724496 scopus 로고    scopus 로고
    • Levodopa-induced dyskinesias and dopamine-dependent stereotypies: A new hypothesis
    • Graybiel, A. M., Canales, J. J. & Capper-Loup, C. Levodopa-induced dyskinesias and dopamine-dependent stereotypies: a new hypothesis. Trends Neurosci. 23, S71-S77 (2000).
    • (2000) Trends Neurosci , vol.23 , pp. S71-S77
    • Graybiel, A.M.1    Canales, J.J.2    Capper-Loup, C.3
  • 188
    • 0030826924 scopus 로고    scopus 로고
    • The basal ganglia and cognitive pattern generators
    • Graybiel, A. M. The basal ganglia and cognitive pattern generators. Schizophr. Bull. 23, 459-469 (1997).
    • (1997) Schizophr. Bull , vol.23 , pp. 459-469
    • Graybiel, A.M.1
  • 189
    • 2142827072 scopus 로고    scopus 로고
    • Neurobehavioral assessment in the information age
    • Tecott, L. H. & Nestler, E. J. Neurobehavioral assessment in the information age. Nat. Neurosci. 7, 462-466 (2004).
    • (2004) Nat Neurosci , vol.7 , pp. 462-466
    • Tecott, L.H.1    Nestler, E.J.2
  • 190
    • 33947317090 scopus 로고    scopus 로고
    • What's wrong with my mouse model? Advances and strategies in animal modeling of anxiety and depression
    • Kalueff, A. V., Wheaton, M. & Murphy, D. L. What's wrong with my mouse model? Advances and strategies in animal modeling of anxiety and depression. Behav. Brain Res. 179, 1-18 (2007).
    • (2007) Behav. Brain Res , vol.179 , pp. 1-18
    • Kalueff, A.V.1    Wheaton, M.2    Murphy, D.L.3
  • 191
    • 80052965386 scopus 로고    scopus 로고
    • Towards high-throughput phenotyping of complex patterned behaviors in rodents: Focus on mouse self-grooming and its sequencing
    • Kyzar, E. et al. Towards high-throughput phenotyping of complex patterned behaviors in rodents: focus on mouse self-grooming and its sequencing. Behav. Brain Res. 225, 426-431 (2011).
    • (2011) Behav. Brain Res , vol.225 , pp. 426-431
    • Kyzar, E.1
  • 192
    • 80855123827 scopus 로고    scopus 로고
    • Social deficits and perseverative behaviors, but not overt aggression, in mao-A hypomorphic mice
    • Bortolato, M. et al. Social deficits and perseverative behaviors, but not overt aggression, in MAO-A hypomorphic mice. Neuropsychopharmacology 36, 2674-2688 (2011).
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2674-2688
    • Bortolato, M.1
  • 193
    • 0345593807 scopus 로고    scopus 로고
    • Inbred roman high-And low-Avoidance rats: Differences in anxiety, novelty-seeking, and shuttlebox behaviors
    • Escorihuela, R. M. et al. Inbred Roman high-And low-Avoidance rats: differences in anxiety, novelty-seeking, and shuttlebox behaviors. Physiol. Behav. 67, 19-26 (1999).
    • (1999) Physiol. Behav , vol.67 , pp. 19-26
    • Escorihuela, R.M.1
  • 194
    • 0029416993 scopus 로고
    • Behavior of the roman/verh high-And low-Avoidance rat lines in anxiety tests: Relationship with defecation and self-grooming
    • Ferre, P. et al. Behavior of the Roman/Verh high-And low-Avoidance rat lines in anxiety tests: relationship with defecation and self-grooming. Physiol. Behav. 58, 1209-1213 (1995).
    • (1995) Physiol. Behav , vol.58 , pp. 1209-1213
    • Ferre, P.1
  • 195
    • 0037343316 scopus 로고    scopus 로고
    • Behavioral differences between selectively bred rats: D1 versus d2 receptors in yawning and grooming
    • Eguibar, J. R., Romero-Carbente, J. C. & Moyaho, A. Behavioral differences between selectively bred rats: D1 versus D2 receptors in yawning and grooming. Pharmacol. Biochem. Behav. 74, 827-832 (2003).
    • (2003) Pharmacol. Biochem. Behav , vol.74 , pp. 827-832
    • Eguibar, J.R.1    Romero-Carbente, J.C.2    Moyaho, A.3
  • 196
    • 0030807482 scopus 로고    scopus 로고
    • Inhibition of grooming by pilocarpine differs in high-And low-yawning sublines of sprague-dawley rats
    • Eguibar, J. R. & Moyaho, A. Inhibition of grooming by pilocarpine differs in high-And low-yawning sublines of Sprague-Dawley rats. Pharmacol. Biochem. Behav. 58, 317-322 (1997).
    • (1997) Pharmacol. Biochem. Behav , vol.58 , pp. 317-322
    • Eguibar, J.R.1    Moyaho, A.2
  • 197
    • 0026783325 scopus 로고
    • Modifications of open field and novelty behaviours by hippocampal and amygdaloid lesions in two inbred strains of mice: Lack of strain x lesion interactions
    • Rossi-Arnaud, C. & Ammassari-Teule, M. Modifications of open field and novelty behaviours by hippocampal and amygdaloid lesions in two inbred strains of mice: lack of strain x lesion interactions. Behav. Processes 27, 155-164 (1992).
    • (1992) Behav. Processes , vol.27 , pp. 155-164
    • Rossi-Arnaud, C.1    Ammassari-Teule, M.2
  • 198
    • 17044367809 scopus 로고    scopus 로고
    • Contrasting grooming phenotypes in three mouse strains markedly different in anxiety and activity (129s1, balb/c and nmri
    • Kalueff, A. V. & Tuohimaa, P. Contrasting grooming phenotypes in three mouse strains markedly different in anxiety and activity (129S1, BALB/c and NMRI). Behav. Brain Res. 160, 1-10 (2005).
    • (2005) Behav. Brain Res , vol.160 , pp. 1-10
    • Kalueff, A.V.1    Tuohimaa, P.2
  • 199
    • 78049523405 scopus 로고    scopus 로고
    • Nutritional up-regulation of serotonin paradoxically induces compulsive behavior
    • Dufour, B. D. et al. Nutritional up-regulation of serotonin paradoxically induces compulsive behavior. Nutr. Neurosci. 13, 256-264 (2010).
    • (2010) Nutr. Neurosci , vol.13 , pp. 256-264
    • Dufour, B.D.1
  • 200
    • 79952986833 scopus 로고    scopus 로고
    • Evaluation of the anxiolytic-like effects of clomipramine in two rat strains with different anxiety vulnerability (wistar and wistar-kyoto rats): Participation of 5-ht1a receptors
    • Rogel-Salazar, G. & Lopez-Rubalcava, C. Evaluation of the anxiolytic-like effects of clomipramine in two rat strains with different anxiety vulnerability (Wistar and Wistar-Kyoto rats): participation of 5-HT1A receptors. Behav. Pharmacol. 22, 136-146 (2011).
    • (2011) Behav. Pharmacol , vol.22 , pp. 136-146
    • Rogel-Salazar, G.1    Lopez-Rubalcava, C.2
  • 201
    • 84930211531 scopus 로고    scopus 로고
    • Suppression of nmda receptor function in mice prenatally exposed to valproic acid improves social deficits and repetitive behaviors
    • Kang, J. & Kim, E. Suppression of NMDA receptor function in mice prenatally exposed to valproic acid improves social deficits and repetitive behaviors. Front. Mol. Neurosci. 8, 17 (2015).
    • (2015) Front. Mol. Neurosci , vol.8 , pp. 17
    • Kang, J.1    Kim, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.