메뉴 건너뛰기




Volumn 16, Issue 5, 1996, Pages 1819-1826

Cell death in the midbrain of the murine mutation weaver

Author keywords

cell death in the midbrain; developmental effects of weaver; genetic causes of cell death; genetic effects on dopamine containing neurons; mesencephalic dopamine containing neurons; murine mutation weaver; neurodegeneration; parkinsonism

Indexed keywords

POTASSIUM CHANNEL;

EID: 0029962959     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-05-01819.1996     Document Type: Article
Times cited : (67)

References (55)
  • 1
    • 84914639435 scopus 로고
    • Estimation of nuclear population from microtome sections
    • Abercrombie M (1946) Estimation of nuclear population from microtome sections. Anat Rec 94:239-247.
    • (1946) Anat Rec , vol.94 , pp. 239-247
    • Abercrombie, M.1
  • 2
    • 1542428962 scopus 로고
    • Developmental mechanisms which may account for strain differences in the number of dopamine neurons in the midbrain
    • (Shagass C, Josiassen RC, Bridger WH, Weiss KJ, Stoff D, Simpson GM, eds), New York: Elsevier
    • Baker H, Reis DJ (1986) Developmental mechanisms which may account for strain differences in the number of dopamine neurons in the midbrain. In: Biological psychiatry (Shagass C, Josiassen RC, Bridger WH, Weiss KJ, Stoff D, Simpson GM, eds), pp 28-30. New York: Elsevier.
    • (1986) Biological Psychiatry , pp. 28-30
    • Baker, H.1    Reis, D.J.2
  • 3
    • 1642493745 scopus 로고
    • Genetic control of number of midbrain dopaminergic neurons in inbred strains of mice: Relationship to size and neuronal density of the striatum
    • Baker H, Joh TH, Reis DJ (1980) Genetic control of number of midbrain dopaminergic neurons in inbred strains of mice: relationship to size and neuronal density of the striatum. Proc Natl Acad Sci USA 77:4369-4373.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 4369-4373
    • Baker, H.1    Joh, T.H.2    Reis, D.J.3
  • 4
    • 0020321480 scopus 로고
    • Time of appearance during development of differences in nigrostriatal tyrosine hydroxylase activity in two inbred mouse strains
    • Baker H, Joh TH, Reis DJ (1982) Time of appearance during development of differences in nigrostriatal tyrosine hydroxylase activity in two inbred mouse strains. Dev Brain Res 4:157-165.
    • (1982) Dev Brain Res , vol.4 , pp. 157-165
    • Baker, H.1    Joh, T.H.2    Reis, D.J.3
  • 5
    • 0020701079 scopus 로고
    • Transneuronal regulation of tyrosine hydroxylase expression in olfactory bulb of mouse and rat
    • Baker H, Kawano T, Margolis FL, Joh TH (1983) Transneuronal regulation of tyrosine hydroxylase expression in olfactory bulb of mouse and rat. J Neurosci 3:69-78.
    • (1983) J Neurosci , vol.3 , pp. 69-78
    • Baker, H.1    Kawano, T.2    Margolis, F.L.3    Joh, T.H.4
  • 6
    • 0027986747 scopus 로고
    • Correlated quantitative studies of the neostriatum, nucleus accumbens, substantia nigra, and ventral tegmental area in normal and weaver mutant mice
    • Bayer SA, Triarhou LC, Thomas JD, Ghetti B (1994) Correlated quantitative studies of the neostriatum, nucleus accumbens, substantia nigra, and ventral tegmental area in normal and weaver mutant mice. J Neurosci 14:6901-6910.
    • (1994) J Neurosci , vol.14 , pp. 6901-6910
    • Bayer, S.A.1    Triarhou, L.C.2    Thomas, J.D.3    Ghetti, B.4
  • 8
    • 0026504044 scopus 로고
    • The weaver gene encodes a nonautonomous signal for CNS neuronal differentiation
    • Gao W-Q, Liu X-L, Halten ME (1992) The weaver gene encodes a nonautonomous signal for CNS neuronal differentiation. Cell 68:841-854.
    • (1992) Cell , vol.68 , pp. 841-854
    • Gao, W.-Q.1    Liu, X.-L.2    Halten, M.E.3
  • 9
    • 0028278417 scopus 로고
    • 28K and of the dopaminergic mesocortical projections in weaver mutant mice
    • 28K and of the dopaminergic mesocortical projections in weaver mutant mice. Neuroscience 61:293-305.
    • (1994) Neuroscience , vol.61 , pp. 293-305
    • Gaspar, P.1    Ben Jelloun, N.2    Febvret, A.3
  • 10
    • 0024673883 scopus 로고
    • The weaver granuloprival phenotype is due to intrinsic action of the mutant locus in granule cells: Evidence from homozygous weaver chimeras
    • Goldowitz D (1989) The weaver granuloprival phenotype is due to intrinsic action of the mutant locus in granule cells: evidence from homozygous weaver chimeras. Neuron 2:1565-1575.
    • (1989) Neuron , vol.2 , pp. 1565-1575
    • Goldowitz, D.1
  • 11
    • 0020461795 scopus 로고
    • Granule cell as a site of gene action in the weaver mouse cerebellum: Evidence from heterozygous mutant chimeras
    • Goldowitz D, Mullen RJ (1982) Granule cell as a site of gene action in the weaver mouse cerebellum: evidence from heterozygous mutant chimeras. J Neurosci 2:1474-1485.
    • (1982) J Neurosci , vol.2 , pp. 1474-1485
    • Goldowitz, D.1    Mullen, R.J.2
  • 12
    • 0025261771 scopus 로고
    • Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. I. Gradients and compartments
    • Graybiel AM, Ohta K, Roffler-Tarlov S (1990) Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. I. Gradients and compartments. J Neurosci 10:720-733.
    • (1990) J Neurosci , vol.10 , pp. 720-733
    • Graybiel, A.M.1    Ohta, K.2    Roffler-Tarlov, S.3
  • 13
    • 0023100259 scopus 로고
    • Selective loss of monoaminergic neurons in weaver mutant mice: An immunocytochemical study
    • Gupta M, Felten DL, Ghetti B (1987) Selective loss of monoaminergic neurons in weaver mutant mice: an immunocytochemical study. Brain Res 402:379-382.
    • (1987) Brain Res , vol.402 , pp. 379-382
    • Gupta, M.1    Felten, D.L.2    Ghetti, B.3
  • 14
    • 0028339063 scopus 로고
    • The male-sterile phenotype of the neurological mutant mouse weaver
    • Harrison SMW, Roffler-Tarlov S (1994) The male-sterile phenotype of the neurological mutant mouse weaver. Dev Dynamics 200:26-38.
    • (1994) Dev Dynamics , vol.200 , pp. 26-38
    • Harrison, S.M.W.1    Roffler-Tarlov, S.2
  • 15
    • 3543123388 scopus 로고
    • Apoptotic and non-apoptotic cell death in the mouse mutant weaver
    • Harrison SMW, Roffler-Tarlov S (1995) Apoptotic and non-apoptotic cell death in the mouse mutant weaver. Soc Neurosci Abstr 424:16.
    • (1995) Soc Neurosci Abstr , vol.424 , pp. 16
    • Harrison, S.M.W.1    Roffler-Tarlov, S.2
  • 16
    • 0022543807 scopus 로고
    • Weaver mouse cerebellar granule neurons fail to migrate on wild-type astroglial processes in vitro
    • Hatten ME, Liem RKH, Mason CA (1986) Weaver mouse cerebellar granule neurons fail to migrate on wild-type astroglial processes in vitro. J Neurosci 6:2676-2683.
    • (1986) J Neurosci , vol.6 , pp. 2676-2683
    • Hatten, M.E.1    Liem, R.K.H.2    Mason, C.A.3
  • 17
    • 0023551058 scopus 로고
    • Regional differences in cytoarchitecture of the weaver cerebellum suggest a new model for weaver gene action
    • Herrup K, Trenkner E (1987) Regional differences in cytoarchitecture of the weaver cerebellum suggest a new model for weaver gene action. Neuroscience 23:871-885.
    • (1987) Neuroscience , vol.23 , pp. 871-885
    • Herrup, K.1    Trenkner, E.2
  • 18
    • 0027407590 scopus 로고
    • Naturally occurring cell death during postnatal development of the substantia nigra pars compacta of rat
    • Janec E, Burke RE (1993) Naturally occurring cell death during postnatal development of the substantia nigra pars compacta of rat. Mol Cell Neurosci 4:30-35.
    • (1993) Mol Cell Neurosci , vol.4 , pp. 30-35
    • Janec, E.1    Burke, R.E.2
  • 19
    • 0023629467 scopus 로고
    • Subdivisions of the dopamine-containing A8-A9-A10 complex identified by their differential mesostriatal innervation of striosomes and extrastriosomal matrix
    • Jiménez-Castellanos J, Graybiel AM (1987) Subdivisions of the dopamine-containing A8-A9-A10 complex identified by their differential mesostriatal innervation of striosomes and extrastriosomal matrix. Neuroscience 23:223-242.
    • (1987) Neuroscience , vol.23 , pp. 223-242
    • Jiménez-Castellanos, J.1    Graybiel, A.M.2
  • 20
    • 0017695435 scopus 로고
    • Contents of serotonin, norepinephrine and dopamine in the cerebrum of the 'staggerer,' 'weaver' and 'nervous' neurologically mutant mice
    • Lane JD, Nadi NS, McBride WJ, Aprison MH, Kusano K (1977) Contents of serotonin, norepinephrine and dopamine in the cerebrum of the 'staggerer,' 'weaver' and 'nervous' neurologically mutant mice. J Neurochem 29:349-350.
    • (1977) J Neurochem , vol.29 , pp. 349-350
    • Lane, J.D.1    Nadi, N.S.2    McBride, W.J.3    Aprison, M.H.4    Kusano, K.5
  • 21
    • 9244235086 scopus 로고
    • The early-forming projections of the substantia nigra in the mutant mouse weaver
    • Martin B, Roffler-Tarlov S (1993) The early-forming projections of the substantia nigra in the mutant mouse weaver. Soc Neurosci Abstr 586:12.
    • (1993) Soc Neurosci Abstr , vol.586 , pp. 12
    • Martin, B.1    Roffler-Tarlov, S.2
  • 22
    • 0027221027 scopus 로고
    • High-resolution mapping of D16Led-1, Gart, Gas-4, Cbr, Pcp-4, and Erg on distal mouse chromosome 16
    • Mjaatvedt AE, Citron MP, Reeves RH (1993) High-resolution mapping of D16Led-1, Gart, Gas-4, Cbr, Pcp-4, and Erg on distal mouse chromosome 16. Genomics 17:382-386.
    • (1993) Genomics , vol.17 , pp. 382-386
    • Mjaatvedt, A.E.1    Citron, M.P.2    Reeves, R.H.3
  • 24
    • 0029115971 scopus 로고
    • A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation
    • Patil N, Cox DR, Bhat D, Faham M, Myers RM, Peterson AS (1995) A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation. Nature Genet 11:126-129.
    • (1995) Nature Genet , vol.11 , pp. 126-129
    • Patil, N.1    Cox, D.R.2    Bhat, D.3    Faham, M.4    Myers, R.M.5    Peterson, A.S.6
  • 26
    • 0015749644 scopus 로고
    • Sequence of developmental abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant mice
    • Rakic P, Sidman RL (1973a) Sequence of developmental abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant mice. J Comp Neurol 152:103-132.
    • (1973) J Comp Neurol , vol.152 , pp. 103-132
    • Rakic, P.1    Sidman, R.L.2
  • 27
    • 0015719472 scopus 로고
    • Organization of cerebellar cortex secondary to deficit of granule cells in weaver mutant mice
    • Rakic P, Sidman RL (1973b) Organization of cerebellar cortex secondary to deficit of granule cells in weaver mutant mice. J Comp Neurol 152:133-161.
    • (1973) J Comp Neurol , vol.152 , pp. 133-161
    • Rakic, P.1    Sidman, R.L.2
  • 28
    • 0024746861 scopus 로고
    • The mouse neurological mutant weaver maps within the region of chromosome 16 that is homologous to human chromosome 21
    • Reeves RH, Crowley MR, Lorenzon N, Pavan WJ, Smeyne RJ, Goldowitz D (1989) The mouse neurological mutant weaver maps within the region of chromosome 16 that is homologous to human chromosome 21. Genomics 5:522-526.
    • (1989) Genomics , vol.5 , pp. 522-526
    • Reeves, R.H.1    Crowley, M.R.2    Lorenzon, N.3    Pavan, W.J.4    Smeyne, R.J.5    Goldowitz, D.6
  • 29
    • 0004267441 scopus 로고
    • A genetic control of the number of dopamine neurons in mouse brain: Its relationship to brain morphology, chemistry, and behavior
    • (Gershon ES, Matthysse S, Breakefield XO, Ciaranello RD, eds), New York: Boxwood
    • Reis DJ, Baker H, Fink JS, Joh TH (1981) A genetic control of the number of dopamine neurons in mouse brain: its relationship to brain morphology, chemistry, and behavior. In: Genetic research strategies for psychobiology and psychiatry (Gershon ES, Matthysse S, Breakefield XO, Ciaranello RD, eds), pp 215-229. New York: Boxwood.
    • (1981) Genetic Research Strategies for Psychobiology and Psychiatry , pp. 215-229
    • Reis, D.J.1    Baker, H.2    Fink, J.S.3    Joh, T.H.4
  • 30
    • 0015398822 scopus 로고
    • Abnormal rate of granule cell migration in the cerebellum of "weaver" mutant mice
    • Rezai Z, Yoon CH (1972) Abnormal rate of granule cell migration in the cerebellum of "weaver" mutant mice. Dev Biol 29:17-26.
    • (1972) Dev Biol , vol.29 , pp. 17-26
    • Rezai, Z.1    Yoon, C.H.2
  • 31
    • 0011336323 scopus 로고
    • The weaver mutation: A murine paradigm of Parkinson's disease
    • (Weiner WJ, Hefti F, eds), Mt. Kisco, NY: Futura
    • Roffler-Tarlov S (1992) The weaver mutation: a murine paradigm of Parkinson's disease. In: Progress In Parkinson's disease, Vol 2, (Weiner WJ, Hefti F, eds), pp 363-374. Mt. Kisco, NY: Futura.
    • (1992) Progress in Parkinson's Disease , vol.2 , pp. 363-374
    • Roffler-Tarlov, S.1
  • 32
    • 0019944876 scopus 로고
    • The content of amino acids in the developing cerebellar cortex and deep cerebellar nuclei of granule cell deficient mutant mice
    • Roffler-Tarlov S, Turey M (1982) The content of amino acids in the developing cerebellar cortex and deep cerebellar nuclei of granule cell deficient mutant mice. Brain Res 247:65-73.
    • (1982) Brain Res , vol.247 , pp. 65-73
    • Roffler-Tarlov, S.1    Turey, M.2
  • 33
    • 0021245295 scopus 로고
    • Weaver mutation has differential effects on the dopamine-containing innervation of the limbic and non-limbic striatum
    • Roffler-Tarlov S, Graybiel AM (1984) Weaver mutation has differential effects on the dopamine-containing innervation of the limbic and non-limbic striatum. Nature 307:62-66.
    • (1984) Nature , vol.307 , pp. 62-66
    • Roffler-Tarlov, S.1    Graybiel, A.M.2
  • 34
    • 0022980571 scopus 로고
    • Expression of the weaver gene in dopamine-containing neural systems is dose-dependent and affects both striatal and nonstriatal regions
    • Roffier-Tarlov S, Graybiel AM (1986) Expression of the weaver gene in dopamine-containing neural systems is dose-dependent and affects both striatal and nonstriatal regions. J Neurosci 6:3319-3330.
    • (1986) J Neurosci , vol.6 , pp. 3319-3330
    • Roffier-Tarlov, S.1    Graybiel, A.M.2
  • 35
    • 0023390552 scopus 로고
    • The postnatal development of the dopamine-containing innervation of dorsal and ventral striatum: Effects of the weaver gene
    • Roffler-Tarlov S, Graybiel AM (1987) The postnatal development of the dopamine-containing innervation of dorsal and ventral striatum: effects of the weaver gene. J Neurosci 7:2364-2372.
    • (1987) J Neurosci , vol.7 , pp. 2364-2372
    • Roffler-Tarlov, S.1    Graybiel, A.M.2
  • 36
    • 0025228462 scopus 로고
    • Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. II. High affinity uptake sites for dopamine
    • Roffler-Tarlov S, Pugatch D, Graybiel AM (1990) Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. II. High affinity uptake sites for dopamine. J Neurosci 10:734-740.
    • (1990) J Neurosci , vol.10 , pp. 734-740
    • Roffler-Tarlov, S.1    Pugatch, D.2    Graybiel, A.M.3
  • 38
    • 0017181361 scopus 로고
    • Strain-dependent variations in number of midbrain dopaminergic neurones
    • Ross RA, Judd AB, Pickel VM, Job TH, Reis DJ (1976) Strain-dependent variations in number of midbrain dopaminergic neurones. Nature 264:654-656.
    • (1976) Nature , vol.264 , pp. 654-656
    • Ross, R.A.1    Judd, A.B.2    Pickel, V.M.3    Job, T.H.4    Reis, D.J.5
  • 41
    • 0024355065 scopus 로고
    • Development and death of external granular layer cells in the weaver mouse cerebellum: A quantitative study
    • Smeyne RJ, Goldowitz D (1989) Development and death of external granular layer cells in the weaver mouse cerebellum: a quantitative study. J Neurosci 9:1608-1620.
    • (1989) J Neurosci , vol.9 , pp. 1608-1620
    • Smeyne, R.J.1    Goldowitz, D.2
  • 42
    • 0025056632 scopus 로고
    • Purkinje cell loss is due to a direct action of the weaver gene in Purkinje cells: Evidence from chimeric mice
    • Smeyne RJ, Goldowitz D (1990) Purkinje cell loss is due to a direct action of the weaver gene in Purkinje cells: evidence from chimeric mice. Dev Brain Res 52:211-218.
    • (1990) Dev Brain Res , vol.52 , pp. 211-218
    • Smeyne, R.J.1    Goldowitz, D.2
  • 43
    • 0025234597 scopus 로고
    • Cell loss and class distribution of TH-I cells in the substantia nigra of the neurological mutant, weaver
    • Smith III MW, Cooper TR, Joh TH, Smith DE (1990) Cell loss and class distribution of TH-I cells in the substantia nigra of the neurological mutant, weaver. Brain Res 510:242-250.
    • (1990) Brain Res , vol.510 , pp. 242-250
    • Smith III, M.W.1    Cooper, T.R.2    Joh, T.H.3    Smith, D.E.4
  • 44
    • 0016412956 scopus 로고
    • Dendritic abnormalities of Purkinje cells in the cerebellum of neurologic mutant mice (weaver and staggerer)
    • Sotelo C (1975) Dendritic abnormalities of Purkinje cells in the cerebellum of neurologic mutant mice (weaver and staggerer). Adv Neurol 12:335-351.
    • (1975) Adv Neurol , vol.12 , pp. 335-351
    • Sotelo, C.1
  • 45
    • 0016152484 scopus 로고
    • Bergmann fibers and granular cell migration in the cerebellum of homozygous weaver mutant mouse
    • Sotelo C, Changeux JP (1974) Bergmann fibers and granular cell migration in the cerebellum of homozygous weaver mutant mouse. Brain Res 77:484-491.
    • (1974) Brain Res , vol.77 , pp. 484-491
    • Sotelo, C.1    Changeux, J.P.2
  • 46
    • 0019411826 scopus 로고
    • Light-microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. I. Early ontogeny
    • Specht LA, Pickel VM, Joh TH, Reis DJ (1981) Light-microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. I. Early ontogeny. J Comp Neurol 199:233-253.
    • (1981) J Comp Neurol , vol.199 , pp. 233-253
    • Specht, L.A.1    Pickel, V.M.2    Joh, T.H.3    Reis, D.J.4
  • 48
    • 0015775446 scopus 로고
    • Time of origin of neurons in the brain stem of the mouse
    • Taber Pierce E (1973) Time of origin of neurons in the brain stem of the mouse. Prog Brain Res 40:53-65.
    • (1973) Prog Brain Res , vol.40 , pp. 53-65
    • Taber Pierce, E.1
  • 49
    • 0024429285 scopus 로고
    • The dendritic dopamine projection of the substantia nigra: Phenotypic denominator of weaver gene action in hetero- and homozygosity
    • Triarhou LC, Ghetti B (1989) The dendritic dopamine projection of the substantia nigra: phenotypic denominator of weaver gene action in hetero- and homozygosity. Brain Res 501:373-381.
    • (1989) Brain Res , vol.501 , pp. 373-381
    • Triarhou, L.C.1    Ghetti, B.2
  • 50
    • 0023944083 scopus 로고
    • Mesencephalic dopamine cell deficit involves areas A8, A9, and A10 in weaver mutant mice
    • Triarhou LC, Norton J, Ghetti B (1988) Mesencephalic dopamine cell deficit involves areas A8, A9, and A10 in weaver mutant mice. Exp Brain Res 70:256-265.
    • (1988) Exp Brain Res , vol.70 , pp. 256-265
    • Triarhou, L.C.1    Norton, J.2    Ghetti, B.3
  • 51
    • 0027731052 scopus 로고
    • Hypospermatogenesis in the cause of infertility in the male weaver mutant mouse
    • Vogelweid CM, Verma T, Norton J, Harruff R, Ghetti B (1993) Hypospermatogenesis in the cause of infertility in the male weaver mutant mouse. J Neurogenet 9:89-104.
    • (1993) J Neurogenet , vol.9 , pp. 89-104
    • Vogelweid, C.M.1    Verma, T.2    Norton, J.3    Harruff, R.4    Ghetti, B.5
  • 52
    • 0027172322 scopus 로고
    • Molecular regulation of apoptosis: Genetic controls on cell death
    • Williams GT, Smith CA (1993) Molecular regulation of apoptosis: genetic controls on cell death. Cell 74:777-779.
    • (1993) Cell , vol.74 , pp. 777-779
    • Williams, G.T.1    Smith, C.A.2
  • 53
    • 0021912141 scopus 로고
    • Effect of the weaver (wv) mutation on cerebellar neuron differentiation. I. Qualitative observations of neuron behavior in culture
    • Willinger M, Margolis DM (1985a) Effect of the weaver (wv) mutation on cerebellar neuron differentiation. I. Qualitative observations of neuron behavior in culture. Dev Biol 107:156-172.
    • (1985) Dev Biol , vol.107 , pp. 156-172
    • Willinger, M.1    Margolis, D.M.2
  • 54
    • 0021992157 scopus 로고
    • Effect of the weaver (wv) mutation on cerebellar neuron differentiation. II. Quantitation of neuron behavior in culture
    • Willinger M, Margolis DM (1985b) Effect of the weaver (wv) mutation on cerebellar neuron differentiation. II. Quantitation of neuron behavior in culture. Dev Biol 107:173-179.
    • (1985) Dev Biol , vol.107 , pp. 173-179
    • Willinger, M.1    Margolis, D.M.2
  • 55
    • 0023491915 scopus 로고
    • Apoptosis: Cell death in tissue regulation
    • Wyllie AH (1987) Apoptosis: cell death in tissue regulation. J Pathol 153:313-316.
    • (1987) J Pathol , vol.153 , pp. 313-316
    • Wyllie, A.H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.