Transgenic mice expressing mutated full-length HD cDNA: A paradigm for locomotor changes and selective neuronal loss in Huntington's disease

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 354, Issue 1386, 1999, Pages 1035-1045

  Reddy, P Hemachandra ^a   Charles, Vinod ^a   Williams, Maya ^a   Miller, Georgina ^b   Whetsell Jr , William O ^c   Tagle, Danilo A ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Huntington's disease; Inclusion bodies; Neurodegeneration; Polyglutamine expansions; Trinucleotide repeat disorder

Indexed keywords

APOPTOSIS; BEHAVIOR; COMPLEMENTARY DNA; DENSITOMETRY; DISEASE MODEL; GENE EXPRESSION; GENE MUTATION; HUNTINGTIN; HUNTINGTON CHOREA; NERVE CELL; PATHOGENESIS; PHENOTYPE; POLYGLUTAMINE; PROMOTER REGION; PROTEIN AGGREGATION; REPETITIVE DNA; SOUTHERN BLOTTING; TRANSGENE; TRANSGENIC MOUSE; WESTERN BLOTTING;

ANIMALIA; CYTOMEGALOVIRUS; MUS MUSCULUS;

EID: 0033614772     PISSN: 09628436     EISSN: None     Source Type: Journal    
DOI: 10.1098/rstb.1999.0456     Document Type: Article

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