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Volumn 79, Issue 1, 2016, Pages 7-16

Learning from animal models of obsessive-compulsive disorder

Author keywords

Animal models; Basal ganglia; CSTC; Obsessive compulsive disorder; OCD; Striatum; Synapse

Indexed keywords

BEHAVIOR; BRAIN CORTEX; CORPUS STRIATUM; EAAC1 GENE; EXPERIMENTAL MODEL; GENE; GENETICS; HOXB8 GENE; HUMAN; HYPERACTIVITY; LEARNING; NEUROPHYSIOLOGY; NONHUMAN; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL; REVIEW; SAPAP GENE; SLC1A1 GENE; SLITRK GENE; THALAMOCORTICAL TRACT; ANIMAL; BRAIN; DISEASE MODEL; PATHOPHYSIOLOGY;

EID: 84948456977     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2015.04.020     Document Type: Review
Times cited : (63)

References (110)
  • 2
    • 72949084907 scopus 로고    scopus 로고
    • The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication
    • A. Ruscio, D. Stein, W. Chiu, and R. Kessler The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication Mol Psychiatry 15 2010 53 63
    • (2010) Mol Psychiatry , vol.15 , pp. 53-63
    • Ruscio, A.1    Stein, D.2    Chiu, W.3    Kessler, R.4
  • 3
    • 15244351436 scopus 로고    scopus 로고
    • Evidence-based pharmacotherapy of obsessive-compulsive disorder
    • N.A. Fineberg, and T.M. Gale Evidence-based pharmacotherapy of obsessive-compulsive disorder Int J Neuropsychopharmacol 8 2005 107 129
    • (2005) Int J Neuropsychopharmacol , vol.8 , pp. 107-129
    • Fineberg, N.A.1    Gale, T.M.2
  • 4
    • 84896719236 scopus 로고    scopus 로고
    • Pharmacological, experimental therapeutic, and transcranial magnetic stimulation treatments for compulsivity and impulsivity
    • S. Pallanti, and E. Hollander Pharmacological, experimental therapeutic, and transcranial magnetic stimulation treatments for compulsivity and impulsivity CNS Spectr 19 2014 50 61
    • (2014) CNS Spectr , vol.19 , pp. 50-61
    • Pallanti, S.1    Hollander, E.2
  • 5
    • 76849110186 scopus 로고    scopus 로고
    • Deep brain stimulation for intractable obsessive compulsive disorder: Pilot study using a blinded, staggered-onset design
    • W.K. Goodman, K.D. Foote, B.D. Greenberg, N. Ricciuti, R. Bauer, H. Ward, and et al. Deep brain stimulation for intractable obsessive compulsive disorder: Pilot study using a blinded, staggered-onset design Biol Psychiatry 67 2010 535 542
    • (2010) Biol Psychiatry , vol.67 , pp. 535-542
    • Goodman, W.K.1    Foote, K.D.2    Greenberg, B.D.3    Ricciuti, N.4    Bauer, R.5    Ward, H.6
  • 6
    • 72949086717 scopus 로고    scopus 로고
    • Deep brain stimulation of the ventral internal capsule/ventral striatum for obsessive-compulsive disorder: Worldwide experience
    • B.D. Greenberg, L.A. Gabriels, D.A. Malone, A.R. Rezai, G.M. Friehs, M.S. Okun, and et al. Deep brain stimulation of the ventral internal capsule/ventral striatum for obsessive-compulsive disorder: Worldwide experience Mol Psychiatry 15 2010 64 79
    • (2010) Mol Psychiatry , vol.15 , pp. 64-79
    • Greenberg, B.D.1    Gabriels, L.A.2    Malone, D.A.3    Rezai, A.R.4    Friehs, G.M.5    Okun, M.S.6
  • 8
    • 80054967901 scopus 로고    scopus 로고
    • Glutamate abnormalities in obsessive compulsive disorder: Neurobiology, pathophysiology, and treatment
    • C. Pittenger, M.H. Bloch, and K. Williams Glutamate abnormalities in obsessive compulsive disorder: Neurobiology, pathophysiology, and treatment Pharmacol Ther 132 2011 314 332
    • (2011) Pharmacol Ther , vol.132 , pp. 314-332
    • Pittenger, C.1    Bloch, M.H.2    Williams, K.3
  • 9
    • 0033855659 scopus 로고    scopus 로고
    • Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder
    • S. Saxena, and S.L. Rauch Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder Psychiatr Clin North Am 23 2000 563 586
    • (2000) Psychiatr Clin North Am , vol.23 , pp. 563-586
    • Saxena, S.1    Rauch, S.L.2
  • 10
    • 84855483229 scopus 로고    scopus 로고
    • Neurobiology of obsessive-compulsive disorder: Insights into neural circuitry dysfunction through mouse genetics
    • J.T. Ting, and G. Feng Neurobiology of obsessive-compulsive disorder: Insights into neural circuitry dysfunction through mouse genetics Curr Opin Neurobiol 21 2011 842 848
    • (2011) Curr Opin Neurobiol , vol.21 , pp. 842-848
    • Ting, J.T.1    Feng, G.2
  • 12
    • 0033636505 scopus 로고    scopus 로고
    • Toward a neurobiology of obsessive-compulsive disorder
    • A.M. Graybiel, and S.L. Rauch Toward a neurobiology of obsessive-compulsive disorder Neuron 28 2000 343 347
    • (2000) Neuron , vol.28 , pp. 343-347
    • Graybiel, A.M.1    Rauch, S.L.2
  • 13
    • 0031846547 scopus 로고    scopus 로고
    • Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder
    • S. Saxena, A.L. Brody, J.M. Schwartz, and L.R. Baxter Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder Br J Psychiatry 173 1998 26 37
    • (1998) Br J Psychiatry , vol.173 , pp. 26-37
    • Saxena, S.1    Brody, A.L.2    Schwartz, J.M.3    Baxter, L.R.4
  • 14
    • 8844286003 scopus 로고    scopus 로고
    • Prefrontal executive and cognitive functions in rodents: Neural and neurochemical substrates
    • J.W. Dalley, R.N. Cardinal, and T.W. Robbins Prefrontal executive and cognitive functions in rodents: Neural and neurochemical substrates Neurosci Biobehav Rev 28 2004 771 784
    • (2004) Neurosci Biobehav Rev , vol.28 , pp. 771-784
    • Dalley, J.W.1    Cardinal, R.N.2    Robbins, T.W.3
  • 15
    • 33745760564 scopus 로고    scopus 로고
    • The role of the basal ganglia in habit formation
    • H.H. Yin, and B.J. Knowlton The role of the basal ganglia in habit formation Nat Rev Neurosci 7 2006 464 476
    • (2006) Nat Rev Neurosci , vol.7 , pp. 464-476
    • Yin, H.H.1    Knowlton, B.J.2
  • 18
    • 23244452169 scopus 로고    scopus 로고
    • The role of the dorsomedial striatum in instrumental conditioning
    • H.H. Yin, S.B. Ostlund, B.J. Knowlton, and B.W. Balleine The role of the dorsomedial striatum in instrumental conditioning Eur J Neurosci 22 2005 513 523
    • (2005) Eur J Neurosci , vol.22 , pp. 513-523
    • Yin, H.H.1    Ostlund, S.B.2    Knowlton, B.J.3    Balleine, B.W.4
  • 19
    • 0034973745 scopus 로고    scopus 로고
    • The prefrontal cortex - An update - Time is of the essence
    • J. Fuster The prefrontal cortex - an update - time is of the essence Neuron 30 2001 319 333
    • (2001) Neuron , vol.30 , pp. 319-333
    • Fuster, J.1
  • 20
    • 84871399321 scopus 로고    scopus 로고
    • The role of medial prefrontal cortex in memory and decision making
    • D.R. Euston, A.J. Gruber, and B.L. McNaughton The role of medial prefrontal cortex in memory and decision making Neuron 76 2012 1057 1070
    • (2012) Neuron , vol.76 , pp. 1057-1070
    • Euston, D.R.1    Gruber, A.J.2    McNaughton, B.L.3
  • 21
    • 4344576360 scopus 로고    scopus 로고
    • Behavioural disorders induced by external globus pallidus dysfunction in primates: I. Behavioural study
    • D. Grabli, K. McCairn, E.C. Hirsch, Y. Agid, J. Féger, C. François, and L. Tremblay Behavioural disorders induced by external globus pallidus dysfunction in primates: I. Behavioural study Brain 127 2004 2039 2054
    • (2004) Brain , vol.127 , pp. 2039-2054
    • Grabli, D.1    McCairn, K.2    Hirsch, E.C.3    Agid, Y.4    Féger, J.5    François, C.6    Tremblay, L.7
  • 22
    • 0030294556 scopus 로고    scopus 로고
    • The basal ganglia: Focused selection and inhibition of competing motor programs
    • J.W. Mink The basal ganglia: Focused selection and inhibition of competing motor programs Prog Neurobiol 50 1996 381 425
    • (1996) Prog Neurobiol , vol.50 , pp. 381-425
    • Mink, J.W.1
  • 23
    • 0025207342 scopus 로고
    • Comparative fine structure of action: Rules of form and sequence in the grooming patterns of six rodent species
    • K.C. Berridge Comparative fine structure of action: Rules of form and sequence in the grooming patterns of six rodent species Behaviour 113 1990 21 56
    • (1990) Behaviour , vol.113 , pp. 21-56
    • Berridge, K.C.1
  • 24
    • 0032053432 scopus 로고    scopus 로고
    • Coding of serial order by neostriatal neurons: A "natural action" approach to movement sequence
    • J.W. Aldridge, and K.C. Berridge Coding of serial order by neostriatal neurons: A "natural action" approach to movement sequence J Neurosci 18 1998 2777 2787
    • (1998) J Neurosci , vol.18 , pp. 2777-2787
    • Aldridge, J.W.1    Berridge, K.C.2
  • 25
    • 27544468773 scopus 로고    scopus 로고
    • Sequential super-stereotypy of an instinctive fixed action pattern in hyper-dopaminergic mutant mice: A model of obsessive compulsive disorder and Tourette's
    • K.C. Berridge, J.W. Aldridge, K.R. Houchard, and X. Zhuang Sequential super-stereotypy of an instinctive fixed action pattern in hyper-dopaminergic mutant mice: A model of obsessive compulsive disorder and Tourette's BMC Biol 3 2005 4
    • (2005) BMC Biol , vol.3 , pp. 4
    • Berridge, K.C.1    Aldridge, J.W.2    Houchard, K.R.3    Zhuang, X.4
  • 26
    • 0021210550 scopus 로고
    • Dissociable effects of 6-OHDA-induced lesions of neostriatum on anorexia, locomotor activity and stereotypy: The role of behavioural competition
    • E.M. Joyce, and S.D. Iversen Dissociable effects of 6-OHDA-induced lesions of neostriatum on anorexia, locomotor activity and stereotypy: The role of behavioural competition Psychopharmacology (Berl) 83 1984 363 366
    • (1984) Psychopharmacology (Berl) , vol.83 , pp. 363-366
    • Joyce, E.M.1    Iversen, S.D.2
  • 27
    • 77952243965 scopus 로고    scopus 로고
    • Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice
    • S.V. Shmelkov, A. Hormigo, D. Jing, C.C. Proenca, K.G. Bath, T. Milde, and et al. Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice Nat Med 16 2010 598 602
    • (2010) Nat Med , vol.16 , pp. 598-602
    • Shmelkov, S.V.1    Hormigo, A.2    Jing, D.3    Proenca, C.C.4    Bath, K.G.5    Milde, T.6
  • 28
    • 34548147472 scopus 로고    scopus 로고
    • Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice
    • J.M. Welch, J. Lu, R.M. Rodriguiz, N.C. Trotta, J. Peca, J.-D. Ding, and et al. Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice Nature 448 2007 894 900
    • (2007) Nature , vol.448 , pp. 894-900
    • Welch, J.M.1    Lu, J.2    Rodriguiz, R.M.3    Trotta, N.C.4    Peca, J.5    Ding, J.-D.6
  • 29
    • 84859338188 scopus 로고    scopus 로고
    • Different dorsal striatum circuits mediate action discrimination and action generalization
    • M. Hilario, T. Holloway, X. Jin, and R.M. Costa Different dorsal striatum circuits mediate action discrimination and action generalization Eur J Neurosci 35 2012 1105 1114
    • (2012) Eur J Neurosci , vol.35 , pp. 1105-1114
    • Hilario, M.1    Holloway, T.2    Jin, X.3    Costa, R.M.4
  • 30
    • 1642580578 scopus 로고    scopus 로고
    • Lesions of dorsolateral striatum preserve outcome expectancy but disrupt habit formation in instrumental learning
    • H.H. Yin, B.J. Knowlton, and B.W. Balleine Lesions of dorsolateral striatum preserve outcome expectancy but disrupt habit formation in instrumental learning Eur J Neurosci 19 2004 181 189
    • (2004) Eur J Neurosci , vol.19 , pp. 181-189
    • Yin, H.H.1    Knowlton, B.J.2    Balleine, B.W.3
  • 31
    • 28944442093 scopus 로고    scopus 로고
    • Inactivation of dorsolateral striatum enhances sensitivity to changes in the action-outcome contingency in instrumental conditioning
    • H.H. Yin, B.J. Knowlton, and B.W. Balleine Inactivation of dorsolateral striatum enhances sensitivity to changes in the action-outcome contingency in instrumental conditioning Behav Brain Res 166 2006 189 196
    • (2006) Behav Brain Res , vol.166 , pp. 189-196
    • Yin, H.H.1    Knowlton, B.J.2    Balleine, B.W.3
  • 32
    • 4043144491 scopus 로고    scopus 로고
    • Contributions of striatal subregions to place and response learning
    • H.H. Yin, and B.J. Knowlton Contributions of striatal subregions to place and response learning Learn Mem 11 2004 459 463
    • (2004) Learn Mem , vol.11 , pp. 459-463
    • Yin, H.H.1    Knowlton, B.J.2
  • 33
    • 84894064742 scopus 로고    scopus 로고
    • Investigating habits: Strategies, technologies and models
    • K.S. Smith, and A.M. Graybiel Investigating habits: Strategies, technologies and models Front Behav Neurosci 8 2014 39
    • (2014) Front Behav Neurosci , vol.8 , pp. 39
    • Smith, K.S.1    Graybiel, A.M.2
  • 34
    • 77953675717 scopus 로고    scopus 로고
    • Differential dynamics of activity changes in dorsolateral and dorsomedial striatal loops during learning
    • C.A. Thorn, H. Atallah, M. Howe, and A.M. Graybiel Differential dynamics of activity changes in dorsolateral and dorsomedial striatal loops during learning Neuron 66 2010 781 795
    • (2010) Neuron , vol.66 , pp. 781-795
    • Thorn, C.A.1    Atallah, H.2    Howe, M.3    Graybiel, A.M.4
  • 36
    • 56349143278 scopus 로고    scopus 로고
    • Striatal plasticity and basal ganglia circuit function
    • A.C. Kreitzer, and R.C. Malenka Striatal plasticity and basal ganglia circuit function Neuron 60 2008 543 554
    • (2008) Neuron , vol.60 , pp. 543-554
    • Kreitzer, A.C.1    Malenka, R.C.2
  • 37
    • 67651017881 scopus 로고    scopus 로고
    • Physiology and pharmacology of striatal neurons
    • A.C. Kreitzer Physiology and pharmacology of striatal neurons Annu Rev Neurosci 32 2009 127 147
    • (2009) Annu Rev Neurosci , vol.32 , pp. 127-147
    • Kreitzer, A.C.1
  • 38
    • 0025298139 scopus 로고
    • Primate models of movement disorders of basal ganglia origin
    • M.R. DeLong Primate models of movement disorders of basal ganglia origin Trends Neurosci 13 1990 281 285
    • (1990) Trends Neurosci , vol.13 , pp. 281-285
    • DeLong, M.R.1
  • 39
    • 0025321039 scopus 로고
    • Functional architecture of basal ganglia circuits: Neural substrates of parallel processing
    • G.E. Alexander, and M.D. Crutcher Functional architecture of basal ganglia circuits: Neural substrates of parallel processing Trends Neurosci 13 1990 266 271
    • (1990) Trends Neurosci , vol.13 , pp. 266-271
    • Alexander, G.E.1    Crutcher, M.D.2
  • 40
    • 0024450903 scopus 로고
    • The functional anatomy of basal ganglia disorders
    • R. Albin, A. Young, and J. Penney The functional anatomy of basal ganglia disorders Trends Neurosci 12 1989 366 375
    • (1989) Trends Neurosci , vol.12 , pp. 366-375
    • Albin, R.1    Young, A.2    Penney, J.3
  • 41
    • 33846077467 scopus 로고    scopus 로고
    • Circuits and circuit disorders of the basal ganglia
    • M.R. DeLong, and T. Wichmann Circuits and circuit disorders of the basal ganglia Arch Neurol 64 2007 20 24
    • (2007) Arch Neurol , vol.64 , pp. 20-24
    • DeLong, M.R.1    Wichmann, T.2
  • 42
    • 84873733797 scopus 로고    scopus 로고
    • Concurrent activation of striatal direct and indirect pathways during action initiation
    • G. Cui, S.B. Jun, X. Jin, M.D. Pham, S.S. Vogel, D.M. Lovinger, and R.M. Costa Concurrent activation of striatal direct and indirect pathways during action initiation Nature 494 2013 238 242
    • (2013) Nature , vol.494 , pp. 238-242
    • Cui, G.1    Jun, S.B.2    Jin, X.3    Pham, M.D.4    Vogel, S.S.5    Lovinger, D.M.6    Costa, R.M.7
  • 44
    • 0034668915 scopus 로고    scopus 로고
    • Intrinsic membrane properties underlying spontaneous tonic firing in neostriatal cholinergic interneurons
    • B.D. Bennett, J.C. Callaway, and C.J. Wilson Intrinsic membrane properties underlying spontaneous tonic firing in neostriatal cholinergic interneurons J Neurosci 20 2000 8493 8503
    • (2000) J Neurosci , vol.20 , pp. 8493-8503
    • Bennett, B.D.1    Callaway, J.C.2    Wilson, C.J.3
  • 45
    • 76649130165 scopus 로고    scopus 로고
    • Distinct roles of GABAergic interneurons in the regulation of striatal output pathways
    • A.H. Gittis, A.B. Nelson, M.T. Thwin, J.J. Palop, and A.C. Kreitzer Distinct roles of GABAergic interneurons in the regulation of striatal output pathways J Neurosci 30 2010 2223 2234
    • (2010) J Neurosci , vol.30 , pp. 2223-2234
    • Gittis, A.H.1    Nelson, A.B.2    Thwin, M.T.3    Palop, J.J.4    Kreitzer, A.C.5
  • 46
    • 5044224808 scopus 로고    scopus 로고
    • GABAergic microcircuits in the neostriatum
    • J.M. Tepper, T. Koós, and C.J. Wilson GABAergic microcircuits in the neostriatum Trends Neurosci 27 2004 662 669
    • (2004) Trends Neurosci , vol.27 , pp. 662-669
    • Tepper, J.M.1    Koós, T.2    Wilson, C.J.3
  • 47
    • 24944572973 scopus 로고    scopus 로고
    • Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome
    • P.S.A. Kalanithi, W. Zheng, Y. Kataoka, M. DiFiglia, H. Grantz, C.B. Saper, and et al. Altered parvalbumin-positive neuron distribution in basal ganglia of individuals with Tourette syndrome Proc Natl Acad Sci U S A 102 2005 13307 13312
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13307-13312
    • Kalanithi, P.S.A.1    Zheng, W.2    Kataoka, Y.3    DiFiglia, M.4    Grantz, H.5    Saper, C.B.6
  • 48
    • 77649251721 scopus 로고    scopus 로고
    • Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome
    • Y. Kataoka, P. Kalanithi, H. Grantz, M.L. Schwartz, C. Saper, J.F. Leckman, and F.M. Vaccarino Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome J Comp Neurol 518 2010 277 291
    • (2010) J Comp Neurol , vol.518 , pp. 277-291
    • Kataoka, Y.1    Kalanithi, P.2    Grantz, H.3    Schwartz, M.L.4    Saper, C.5    Leckman, J.F.6    Vaccarino, F.M.7
  • 49
    • 84878750990 scopus 로고    scopus 로고
    • Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors
    • E. Burguière, P. Monteiro, G. Feng, and A.M. Graybiel Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors Science 340 2013 1243 1246
    • (2013) Science , vol.340 , pp. 1243-1246
    • Burguière, E.1    Monteiro, P.2    Feng, G.3    Graybiel, A.M.4
  • 50
    • 84858662491 scopus 로고    scopus 로고
    • Optogenetic investigation of neural circuits underlying brain disease in animal models
    • K.M. Tye, and K. Deisseroth Optogenetic investigation of neural circuits underlying brain disease in animal models Nat Rev Neurosci 13 2012 251 266
    • (2012) Nat Rev Neurosci , vol.13 , pp. 251-266
    • Tye, K.M.1    Deisseroth, K.2
  • 51
    • 33749020262 scopus 로고    scopus 로고
    • Channelrhodopsin-2 and optical control of excitable cells
    • F. Zhang, L. Wang, E.S. Boyden, and K. Deisseroth Channelrhodopsin-2 and optical control of excitable cells Nat Methods 3 2006 785 792
    • (2006) Nat Methods , vol.3 , pp. 785-792
    • Zhang, F.1    Wang, L.2    Boyden, E.S.3    Deisseroth, K.4
  • 53
    • 0035949351 scopus 로고    scopus 로고
    • DeltaFosB: A sustained molecular switch for addiction
    • E.J. Nestler, M. Barrot, and D.W. Self DeltaFosB: A sustained molecular switch for addiction Proc Natl Acad Sci U S A 98 2001 11042 11046
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 11042-11046
    • Nestler, E.J.1    Barrot, M.2    Self, D.W.3
  • 54
    • 0027051872 scopus 로고
    • Neurobiology of obsessive compulsive disorder
    • T.R. Insel, and J.T. Winslow Neurobiology of obsessive compulsive disorder Psychiatr Clin North Am 15 1992 813 824
    • (1992) Psychiatr Clin North Am , vol.15 , pp. 813-824
    • Insel, T.R.1    Winslow, J.T.2
  • 55
    • 84904004407 scopus 로고    scopus 로고
    • Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors
    • P.E. Rothwell, M.V. Fuccillo, S. Maxeiner, S.J. Hayton, O. Gokce, B.K. Lim, and et al. Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors Cell 15 2014 198 212
    • (2014) Cell , vol.15 , pp. 198-212
    • Rothwell, P.E.1    Fuccillo, M.V.2    Maxeiner, S.3    Hayton, S.J.4    Gokce, O.5    Lim, B.K.6
  • 56
    • 84901029710 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder: An integrative genetic and neurobiological perspective
    • D.L. Pauls, A. Abramovitch, S.L. Rauch, and D.A. Geller Obsessive-compulsive disorder: An integrative genetic and neurobiological perspective Nat Rev Neurosci 15 2014 410 424
    • (2014) Nat Rev Neurosci , vol.15 , pp. 410-424
    • Pauls, D.L.1    Abramovitch, A.2    Rauch, S.L.3    Geller, D.A.4
  • 57
    • 84856289525 scopus 로고    scopus 로고
    • When too much is not enough: Obsessive-compulsive disorder as a pathology of stopping, rather than starting
    • A.L. Hinds, E.Z. Woody, M. Van Ameringen, L.A. Schmidt, and H. Szechtman When too much is not enough: Obsessive-compulsive disorder as a pathology of stopping, rather than starting PLoS One 7 2012 e30586
    • (2012) PLoS One , vol.7 , pp. e30586
    • Hinds, A.L.1    Woody, E.Z.2    Van Ameringen, M.3    Schmidt, L.A.4    Szechtman, H.5
  • 59
    • 84855312031 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder: Beyond segregated cortico-striatal pathways
    • M.R. Milad, and S.L. Rauch Obsessive-compulsive disorder: Beyond segregated cortico-striatal pathways Trends Cogn Sci 16 2012 43 51
    • (2012) Trends Cogn Sci , vol.16 , pp. 43-51
    • Milad, M.R.1    Rauch, S.L.2
  • 62
    • 0141592297 scopus 로고    scopus 로고
    • Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth
    • J. Aruga, and K. Mikoshiba Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth Mol Cell Neurosci 24 2003 117 129
    • (2003) Mol Cell Neurosci , vol.24 , pp. 117-129
    • Aruga, J.1    Mikoshiba, K.2
  • 63
    • 0021739656 scopus 로고
    • Genetic and environmental influences on obsessional traits and symptoms
    • C.A. Clifford, R.M. Murray, and D.W. Fulker Genetic and environmental influences on obsessional traits and symptoms Psychol Med 14 1984 791 800
    • (1984) Psychol Med , vol.14 , pp. 791-800
    • Clifford, C.A.1    Murray, R.M.2    Fulker, D.W.3
  • 64
    • 84878127194 scopus 로고    scopus 로고
    • Obsessive-compulsive disorder and obsessive-compulsive spectrum disorders: Diagnostic and dimensional issues
    • E. Hollander, S. Kim, S. Khanna, and S. Pallanti Obsessive-compulsive disorder and obsessive-compulsive spectrum disorders: Diagnostic and dimensional issues CNS Spectr 12 suppl 3 2007 5 13
    • (2007) CNS Spectr , vol.12 , pp. 5-13
    • Hollander, E.1    Kim, S.2    Khanna, S.3    Pallanti, S.4
  • 69
    • 64849109213 scopus 로고    scopus 로고
    • A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder
    • J.R. Wendland, P.R. Moya, K.R. Timpano, A.P. Anavitarte, M.R. Kruse, M.G. Wheaton, and et al. A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder Arch Gen Psychiatry 66 2009 408 416
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 408-416
    • Wendland, J.R.1    Moya, P.R.2    Timpano, K.R.3    Anavitarte, A.P.4    Kruse, M.R.5    Wheaton, M.G.6
  • 71
    • 0030976929 scopus 로고    scopus 로고
    • Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration
    • P. Peghini, J. Janzen, and W. Stoffel Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration EMBO J 16 1997 3822 3832
    • (1997) EMBO J , vol.16 , pp. 3822-3832
    • Peghini, P.1    Janzen, J.2    Stoffel, W.3
  • 72
    • 29444459269 scopus 로고    scopus 로고
    • Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse
    • K. Aoyama, S.W. Suh, A.M. Hamby, J. Liu, W.Y. Chan, Y. Chen, and R.A. Swanson Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse Nat Neurosci 9 2006 119 126
    • (2006) Nat Neurosci , vol.9 , pp. 119-126
    • Aoyama, K.1    Suh, S.W.2    Hamby, A.M.3    Liu, J.4    Chan, W.Y.5    Chen, Y.6    Swanson, R.A.7
  • 73
    • 84855562649 scopus 로고    scopus 로고
    • The role of glutamate signaling in the pathogenesis and treatment of obsessive-compulsive disorder
    • K. Wu, G. Hanna, D. Rosenberg, and P. Arnold The role of glutamate signaling in the pathogenesis and treatment of obsessive-compulsive disorder Pharmacol Biochem Behav 100 2012 726 735
    • (2012) Pharmacol Biochem Behav , vol.100 , pp. 726-735
    • Wu, K.1    Hanna, G.2    Rosenberg, D.3    Arnold, P.4
  • 74
    • 84878263397 scopus 로고    scopus 로고
    • Association between SLC1A1 gene and early-onset OCD in the han Chinese population: A case-control study
    • H. Wu, X. Wang, Z. Xiao, S. Yu, L. Zhu, D. Wang, and et al. Association between SLC1A1 gene and early-onset OCD in the han chinese population: A case-control study J Mol Neurosci 50 2013 353 359
    • (2013) J Mol Neurosci , vol.50 , pp. 353-359
    • Wu, H.1    Wang, X.2    Xiao, Z.3    Yu, S.4    Zhu, L.5    Wang, D.6
  • 76
    • 81255211947 scopus 로고    scopus 로고
    • Sapap3 deletion causes mGluR5-dependent silencing of AMPAR synapses
    • Y. Wan, G. Feng, and N. Calakos Sapap3 deletion causes mGluR5-dependent silencing of AMPAR synapses J Neurosci 31 2011 16685 16691
    • (2011) J Neurosci , vol.31 , pp. 16685-16691
    • Wan, Y.1    Feng, G.2    Calakos, N.3
  • 77
    • 84897107762 scopus 로고    scopus 로고
    • Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder
    • Y. Wan, K.K. Ade, Z. Caffall, M. Ilcim Ozlu, C. Eroglu, G. Feng, and N. Calakos Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder Biol Psychiatry 75 2014 623 630
    • (2014) Biol Psychiatry , vol.75 , pp. 623-630
    • Wan, Y.1    Ade, K.K.2    Caffall, Z.3    Ilcim Ozlu, M.4    Eroglu, C.5    Feng, G.6    Calakos, N.7
  • 78
    • 79959943160 scopus 로고    scopus 로고
    • Sapap3 deletion anomalously activates short-term endocannabinoid-mediated synaptic plasticity
    • M. Chen, Y. Wan, K. Ade, J. Ting, G. Feng, and N. Calakos Sapap3 deletion anomalously activates short-term endocannabinoid-mediated synaptic plasticity J Neurosci 31 2011 9563 9573
    • (2011) J Neurosci , vol.31 , pp. 9563-9573
    • Chen, M.1    Wan, Y.2    Ade, K.3    Ting, J.4    Feng, G.5    Calakos, N.6
  • 81
    • 79551600821 scopus 로고    scopus 로고
    • Investigating SAPAP3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population
    • L. Boardman, L. Van Der Merwe, C. Lochner, C.J. Kinnear, S. Seedat, D.J. Stein, and et al. Investigating SAPAP3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population Compr Psychiatry 52 2011 181 187
    • (2011) Compr Psychiatry , vol.52 , pp. 181-187
    • Boardman, L.1    Van Der Merwe, L.2    Lochner, C.3    Kinnear, C.J.4    Seedat, S.5    Stein, D.J.6
  • 83
    • 79952252418 scopus 로고    scopus 로고
    • Slitrks as emerging candidate genes involved in neuropsychiatric disorders
    • C. Proenca, K. Gao, S. Shmelkov, S. Rafii, and F.S. Lee Slitrks as emerging candidate genes involved in neuropsychiatric disorders Trends Neurosci 34 2011 143 153
    • (2011) Trends Neurosci , vol.34 , pp. 143-153
    • Proenca, C.1    Gao, K.2    Shmelkov, S.3    Rafii, S.4    Lee, F.S.5
  • 86
    • 0037121261 scopus 로고    scopus 로고
    • Tourette's syndrome
    • J.F. Leckman Tourette's syndrome Lancet 360 2002 1577 1586
    • (2002) Lancet , vol.360 , pp. 1577-1586
    • Leckman, J.F.1
  • 87
    • 0141483178 scopus 로고    scopus 로고
    • Human SLITRK family genes: Genomic organization and expression profiling in normal brain and brain tumor tissue
    • J. Aruga, N. Yokota, and K. Mikoshiba Human SLITRK family genes: Genomic organization and expression profiling in normal brain and brain tumor tissue Gene 315 2003 87 94
    • (2003) Gene , vol.315 , pp. 87-94
    • Aruga, J.1    Yokota, N.2    Mikoshiba, K.3
  • 88
    • 0037012082 scopus 로고    scopus 로고
    • Hoxb8 is required for normal grooming behavior in mice
    • J.M. Greer, and M.R. Capecchi Hoxb8 is required for normal grooming behavior in mice Neuron 33 2002 23 34
    • (2002) Neuron , vol.33 , pp. 23-34
    • Greer, J.M.1    Capecchi, M.R.2
  • 90
    • 84860338445 scopus 로고    scopus 로고
    • The complement system: An unexpected role in synaptic pruning during development and disease
    • A.H. Stephan, B.A. Barres, and B. Stevens The complement system: An unexpected role in synaptic pruning during development and disease Annu Rev Neurosci 35 2012 369 389
    • (2012) Annu Rev Neurosci , vol.35 , pp. 369-389
    • Stephan, A.H.1    Barres, B.A.2    Stevens, B.3
  • 92
    • 77956419151 scopus 로고    scopus 로고
    • The immunobiology of Tourette's disorder, pediatric autoimmune neuropsychiatric disorders associated with Streptococcus, and related disorders: A way forward
    • T.K. Murphy, R. Kurlan, and J. Leckman The immunobiology of Tourette's disorder, pediatric autoimmune neuropsychiatric disorders associated with Streptococcus, and related disorders: A way forward J Child Adolesc Psychopharmacol 20 2010 317 331
    • (2010) J Child Adolesc Psychopharmacol , vol.20 , pp. 317-331
    • Murphy, T.K.1    Kurlan, R.2    Leckman, J.3
  • 93
    • 41549167783 scopus 로고    scopus 로고
    • Serotoninergic mechanisms in the treatment of obsessive-compulsive disorder
    • A.W. Goddard, A. Shekhar, A.F. Whiteman, and C.J. McDougle Serotoninergic mechanisms in the treatment of obsessive-compulsive disorder Drug Discov Today 13 2008 325 332
    • (2008) Drug Discov Today , vol.13 , pp. 325-332
    • Goddard, A.W.1    Shekhar, A.2    Whiteman, A.F.3    McDougle, C.J.4
  • 95
    • 67649321877 scopus 로고    scopus 로고
    • Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function
    • L. Abdallah, S.J. Bonasera, F.W. Hopf, L. O'Dell, M. Giorgetti, M. Jongsma, and et al. Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function J Neurosci 29 2009 8156 8165
    • (2009) J Neurosci , vol.29 , pp. 8156-8165
    • Abdallah, L.1    Bonasera, S.J.2    Hopf, F.W.3    O'Dell, L.4    Giorgetti, M.5    Jongsma, M.6
  • 96
    • 1642285042 scopus 로고    scopus 로고
    • Contributions of 5-HT2C receptors to multiple actions of central serotonin systems
    • M. Giorgetti, and L.H. Tecott Contributions of 5-HT2C receptors to multiple actions of central serotonin systems Eur J Pharmacol 488 2004 1 9
    • (2004) Eur J Pharmacol , vol.488 , pp. 1-9
    • Giorgetti, M.1    Tecott, L.H.2
  • 98
    • 84896449195 scopus 로고    scopus 로고
    • Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder
    • R. Tang, H. Noh, D. Wang, S. Sigurdsson, R. Swofford, M. Perloski, and et al. Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder Genome Biol 15 2014 R25
    • (2014) Genome Biol , vol.15 , pp. R25
    • Tang, R.1    Noh, H.2    Wang, D.3    Sigurdsson, S.4    Swofford, R.5    Perloski, M.6
  • 99
    • 84873119870 scopus 로고    scopus 로고
    • Asymmetric N-cadherin expression results in synapse dysfunction, synapse elimination, and axon retraction in cultured mouse neurons
    • K.N. Pielarski, B. van Stegen, A. Andreyeva, K. Nieweg, K. Jüngling, C. Redies, and K. Gottmann Asymmetric N-cadherin expression results in synapse dysfunction, synapse elimination, and axon retraction in cultured mouse neurons PLoS One 8 2013 e54105
    • (2013) PLoS One , vol.8 , pp. e54105
    • Pielarski, K.N.1    Van Stegen, B.2    Andreyeva, A.3    Nieweg, K.4    Jüngling, K.5    Redies, C.6    Gottmann, K.7
  • 101
    • 0022930826 scopus 로고
    • Parallel organization of functionally segregated circuits linking basal ganglia and cortex
    • G. Alexander, M.R. DeLong, and P. Strick Parallel organization of functionally segregated circuits linking basal ganglia and cortex Annu Rev Neurosci 9 1986 357 381
    • (1986) Annu Rev Neurosci , vol.9 , pp. 357-381
    • Alexander, G.1    DeLong, M.R.2    Strick, P.3
  • 102
    • 0037107159 scopus 로고    scopus 로고
    • Synaptic convergence of motor and somatosensory cortical afferents onto GABAergic interneurons in the rat striatum
    • S. Ramanathan, J.J. Hanley, J.-M. Deniau, and J.P. Bolam Synaptic convergence of motor and somatosensory cortical afferents onto GABAergic interneurons in the rat striatum J Neurosci 22 2002 8158 8169
    • (2002) J Neurosci , vol.22 , pp. 8158-8169
    • Ramanathan, S.1    Hanley, J.J.2    Deniau, J.-M.3    Bolam, J.P.4
  • 103
    • 80955145185 scopus 로고    scopus 로고
    • Functional properties of striatal fast-spiking interneurons
    • J.D. Berke Functional properties of striatal fast-spiking interneurons Front Syst Neurosci 5 2011 45
    • (2011) Front Syst Neurosci , vol.5 , pp. 45
    • Berke, J.D.1
  • 104
    • 0028113346 scopus 로고
    • Synaptic input and output of parvalbumin-immunoreactive neurons in the neostriatum of the rat
    • B. Bennett, and J. Bolam Synaptic input and output of parvalbumin-immunoreactive neurons in the neostriatum of the rat Neuroscience 62 1994 707 719
    • (1994) Neuroscience , vol.62 , pp. 707-719
    • Bennett, B.1    Bolam, J.2
  • 105
    • 0038744836 scopus 로고    scopus 로고
    • Inhibitory control of neostriatal projection neurons by GABAergic interneurons
    • T. Koós, and J.M. Tepper Inhibitory control of neostriatal projection neurons by GABAergic interneurons Nat Neurosci 2 1999 467 472
    • (1999) Nat Neurosci , vol.2 , pp. 467-472
    • Koós, T.1    Tepper, J.M.2
  • 106
    • 34247885788 scopus 로고    scopus 로고
    • GABAergic inhibition in the neostriatum
    • C.J. Wilson GABAergic inhibition in the neostriatum Prog Brain Res 160 2007 91 110
    • (2007) Prog Brain Res , vol.160 , pp. 91-110
    • Wilson, C.J.1
  • 107
    • 0023853933 scopus 로고
    • Cholinergic synaptic input to different parts of spiny striatonigral neurons in the rat
    • P.N. Izzo, and J.P. Bolam Cholinergic synaptic input to different parts of spiny striatonigral neurons in the rat J Comp Neurol 269 1988 219 234
    • (1988) J Comp Neurol , vol.269 , pp. 219-234
    • Izzo, P.N.1    Bolam, J.P.2
  • 108
    • 0037080161 scopus 로고    scopus 로고
    • Dual cholinergic control of fast-spiking interneurons in the neostriatum
    • T. Koós, and J.M. Tepper Dual cholinergic control of fast-spiking interneurons in the neostriatum J Neurosci 22 2002 529 535
    • (2002) J Neurosci , vol.22 , pp. 529-535
    • Koós, T.1    Tepper, J.M.2
  • 109
    • 49649099562 scopus 로고    scopus 로고
    • Feedforward and feedback inhibition in neostriatal GABAergic spiny neurons
    • J.M. Tepper, C.J. Wilson, and T. Koós Feedforward and feedback inhibition in neostriatal GABAergic spiny neurons Brain Res Rev 58 2008 272 281
    • (2008) Brain Res Rev , vol.58 , pp. 272-281
    • Tepper, J.M.1    Wilson, C.J.2    Koós, T.3
  • 110
    • 58149166933 scopus 로고    scopus 로고
    • Dichotomous anatomical properties of adult striatal medium spiny neurons
    • T.S. Gertler, C.S. Chan, and D.J. Surmeier Dichotomous anatomical properties of adult striatal medium spiny neurons J Neurosci 28 2008 10814 10824
    • (2008) J Neurosci , vol.28 , pp. 10814-10824
    • Gertler, T.S.1    Chan, C.S.2    Surmeier, D.J.3


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