Loss of glutamic acid decarboxylase (Gad67) in Gpr88-expressing neurons induces learning and social behavior deficits in mice

Neuroscience

Volumn 275, Issue , 2014, Pages 238-247

  Zhang, K ^a   Hill, K ^a   Labak, S ^a   Blatt, G J ^a,b   Soghomonian, J J ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Hussman Institute for Autism   (United States)

Author keywords

Conditional knockout; GABA; Glutamic acid decarboxylase; Learning; Social behavior; Striatum

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 88; GLUTAMATE DECARBOXYLASE 67; UNCLASSIFIED DRUG; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 1; GPR88 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTISOCIAL PERSONALITY DISORDER; ANXIETY; ARTICLE; BEHAVIOR CHANGE; CONTROLLED STUDY; DISEASE ACTIVITY; FUNCTIONAL ASSESSMENT; LEARNING DISORDER; MALE; MOLECULAR PATHOLOGY; MOTOR PERFORMANCE; MOUSE; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SMELLING; SOCIAL INTERACTION; SPATIAL LEARNING; VISUAL MEMORY; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CORPUS STRIATUM; DEFICIENCY; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MAZE TEST; METABOLISM; NERVE CELL; PHYSIOLOGY; SOCIAL BEHAVIOR; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CORPUS STRIATUM; GLUTAMATE DECARBOXYLASE; IMMUNOHISTOCHEMISTRY; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; RECEPTORS, G-PROTEIN-COUPLED; SOCIAL BEHAVIOR;

EID: 84903770145     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.06.020     Document Type: Article

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