Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice

Nature Medicine

Volumn 16, Issue 5, 2010, Pages 598-602

  Shmelkov, Sergey V ^a   Hormigo, Adília ^a,b,c   Jing, Deqiang ^c   Proenca, Catia C ^c,d   Bath, Kevin G ^c   Milde, Till ^a   Shmelkov, Evgeny ^a   Kushner, Jared S ^a   Baljevic, Muhamed ^a   Dincheva, Iva ^c   Murphy, Andrew J ^e   Valenzuela, David M ^e   Gale, Nicholas W ^e   Yancopoulos, George D ^e   Ninan, Ipe ^f   Lee, Francis S ^c   Rafii, Shahin ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

^e REGENERON PHARMACEUTICALS INC   (United States)

^f NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUOXETINE; GLUTAMATE RECEPTOR; MEMBRANE PROTEIN; PROTEIN SLITRK5; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BRAIN METABOLISM; CELL STRUCTURE; MOUSE; NEUROTRANSMISSION; NONHUMAN; OBSESSIVE COMPULSIVE DISORDER; ORBITAL CORTEX; PRIORITY JOURNAL; PROTEIN DEFICIENCY; STRIATE CORTEX;

ANIMALS; BEHAVIOR, ANIMAL; COMPULSIVE BEHAVIOR; GROOMING; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NEOSTRIATUM; NERVE TISSUE PROTEINS; OBSESSIVE-COMPULSIVE DISORDER; SYNAPSES; SYNAPTIC TRANSMISSION;

MUS;

EID: 77952243965     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2125     Document Type: Article

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