Protective effects of 3-alkyl luteolin derivatives are mediated by Nrf2 transcriptional activity and decreased oxidative stress in Huntington's disease mouse striatal cells

Neurochemistry International

Volumn 91, Issue , 2015, Pages 1-12

  Oliveira, Ana M ^a,c   Cardoso, Susana M ^a,b   Ribeiro, Márcio ^c   Seixas, Raquel S G R ^a   Silva, Artur M S ^a   Rego, A Cristina ^c,d  

^a UNIVERSITY OF AVEIRO   (Portugal)

^b POLYTECHNIC INSTITUTE OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Glutamate cysteine ligase catalytic subunit; Huntington's disease; Luteolin; Nuclear factor (erythroid derived 2) like 2; Oxidative stress; Superoxide dismutase

Indexed keywords

3 ALKYL LUTEOLIN DERIVATIVE; CASPASE 3; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTAMATE CYSTEINE LIGASE; LUTEOLIN; MESSENGER RNA; MUTANT PROTEIN; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; CASP3 PROTEIN, MOUSE; NFE2L2 PROTEIN, MOUSE; SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, MOUSE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN CELL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFECT; ENZYME ACTIVITY; HUNTINGTON CHOREA; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; ANIMAL; BIOSYNTHESIS; CELL LINE; DRUG EFFECTS; GENE TARGETING; GENETICS; HUNTINGTON DISEASE; METABOLISM; NEOSTRIATUM; NERVE CELL;

ANIMALS; CASPASE 3; CELL LINE; GENE KNOCK-IN TECHNIQUES; GLUTAMATE-CYSTEINE LIGASE; HUNTINGTON DISEASE; LUTEOLIN; MICE; NEOSTRIATUM; NEURONS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SUPEROXIDE DISMUTASE;

EID: 84950980628     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2015.10.004     Document Type: Article

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