Luteolin modulates 6-hydroxydopamine-induced transcriptional changes of stress response pathways in PC12 cells

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Hu, Ling Wei ^a   Yen, Jui Hung ^b   Shen, Yi Ting ^a   Wu, Kuan Yi ^a   Wu, Ming Jiuan ^a  

^a CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^b TZU CHI UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CASPASE 3; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; LUTEOLIN; MESSENGER RNA; OXIDOPAMINE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; ACTIVATING TRANSCRIPTION FACTOR 6; HEAT SHOCK PROTEIN; HSPA5 PROTEIN, RAT; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ARTICLE; ATF4 GENE; BIM GENE; CELL CYCLE ARREST; CELLULAR STRESS RESPONSE; CHOP GENE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; GADD34 GENE; GADD45ALPHA GENE; GENE; GENE EXPRESSION; GRP78 GENE; NONHUMAN; P21 GENE; P53 GENE; PC12 CELL LINE; PROTEIN PHOSPHORYLATION; PUMA GENE; RAT; TRANSCRIPTION INITIATION; TRB3 GENE; UNFOLDED PROTEIN RESPONSE; ANIMAL; APOPTOSIS; CELL CYCLE CHECKPOINT; CELL SURVIVAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHYSIOLOGICAL STRESS; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL SURVIVAL; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; LUTEOLIN; NF-E2-RELATED FACTOR 2; OXIDOPAMINE; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84901328510     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097880     Document Type: Article

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