The effect and role of carbon atoms in Poly(β-amino ester)s for DNA binding and gene delivery

Journal of the American Chemical Society

Volumn 135, Issue 18, 2013, Pages 6951-6957

  Bishop, Corey J ^a   Ketola, Tiia Maaria ^b   Tzeng, Stephany Y ^a   Sunshine, Joel C ^a   Urtti, Arto ^c   Lemmetyinen, Helge ^b   Vuorimaa Laukkanen, Elina ^b   Yliperttula, Marjo ^c   Green, Jordan J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING CONSTANT; CLINICAL APPLICATION; GENE DELIVERY; HUMAN BREAST; OPTIMAL VALUES; POLYMER MOLECULAR WEIGHT; RATIONAL DESIGN; STRUCTURE-FUNCTION RELATIONSHIP;

BIOLOGICAL MATERIALS; CELL CULTURE; ESTERIFICATION; ESTERS; GENE TRANSFER; MOLECULAR BIOLOGY; RATIONAL FUNCTIONS;

POLYMERS;

CARBON; DNA; ESTER DERIVATIVE; POLY(BETA AMINO ESTER); POLYMER; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; BRAIN CANCER; BREAST CANCER; CANCER CELL CULTURE; CHEMICAL BINDING; CHEMICAL STRUCTURE; CONTROLLED STUDY; DNA BINDING; DRUG CYTOTOXICITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; ZETA POTENTIAL;

ANTINEOPLASTIC AGENTS; BINDING SITES; CARBON; CELL LINE, TUMOR; CELL PROLIFERATION; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; POLYMERS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84877302522     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja4002376     Document Type: Article

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