Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery

ACS Nano

Volumn 6, Issue 9, 2012, Pages 8041-8051

  Demuth, Peter C ^a   Moon, James J ^a   Suh, Heikyung ^a,c   Hammond, Paula T ^a,b   Irvine, Darrell J ^a,b,c  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

biodegradable; layer by layer; microneedles; polymer assembly; transcutaneous delivery; vaccine

Indexed keywords

BIODEGRADABLE; LAYER-BY-LAYERS; MICRONEEDLES; POLYMER ASSEMBLIES; TRANSCUTANEOUS DELIVERY;

ANTIGENS; BIODEGRADABLE POLYMERS; CROSSLINKING; DRUG DELIVERY; IMMUNOLOGY; MULTILAYER FILMS; NANOCAPSULES; PROTEINS; TISSUE; VACCINES;

NEEDLES;

LIPID; NANOCAPSULE; VACCINE;

ANIMAL; ARTICLE; C57BL MOUSE; CHEMISTRY; DELAYED RELEASE FORMULATION; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FEMALE; INSTRUMENTATION; METHODOLOGY; MICROINJECTION; MOUSE; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; DELAYED-ACTION PREPARATIONS; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FEMALE; INJECTIONS, SUBCUTANEOUS; LIPIDS; MICE; MICE, INBRED C57BL; MICROINJECTIONS; NANOCAPSULES; VACCINES;

EID: 84866670385     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn302639r     Document Type: Article

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