메뉴 건너뛰기




Volumn 6, Issue 11, 2006, Pages 2622-2635

The role of hyaluronan degradation products as innate alloimmune agonists

Author keywords

Dendritic cell; Toll like receptor

Indexed keywords

CHEMOKINE RECEPTOR CCR7; GLYCOSAMINOGLYCAN; HYALURONIC ACID; HYALURONIC ACID DERIVATIVE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR ALPHA;

EID: 33750024480     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2006.01537.x     Document Type: Article
Times cited : (176)

References (58)
  • 1
    • 0035838984 scopus 로고    scopus 로고
    • Dendritic cells: Specialized and regulated antigen processing machines
    • Mellman I, Steinman RM. Dendritic cells: Specialized and regulated antigen processing machines. Cell 2001; 106: 255-258.
    • (2001) Cell , vol.106 , pp. 255-258
    • Mellman, I.1    Steinman, R.M.2
  • 2
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S, Takeda K. Toll-like receptor signalling. Nat Rev Immunol 2004; 4: 499-511.
    • (2004) Nat Rev Immunol , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 3
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki A, Medzhitov R. Toll-like receptor control of the adaptive immune responses. Nat Immunol 2004; 5: 987-995.
    • (2004) Nat Immunol , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 4
    • 0037505362 scopus 로고    scopus 로고
    • The Toll-IL-1 receptor adaptor family grows to five members
    • O'Neill LAJ, Fitzgerald KA, Bowie AG. The Toll-IL-1 receptor adaptor family grows to five members. Trends Immunol 2003; 24: 286-289.
    • (2003) Trends Immunol , vol.24 , pp. 286-289
    • O'Neill, L.A.J.1    Fitzgerald, K.A.2    Bowie, A.G.3
  • 5
    • 0037153191 scopus 로고    scopus 로고
    • Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
    • Yamamoto M, Sato S, Hemmi H et al. Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 2002; 420: 324-329.
    • (2002) Nature , vol.420 , pp. 324-329
    • Yamamoto, M.1    Sato, S.2    Hemmi, H.3
  • 6
    • 0037153130 scopus 로고    scopus 로고
    • The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
    • Horng T, Barton GM, Flavell RA, Medzhitov R. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 2002; 420: 329-333.
    • (2002) Nature , vol.420 , pp. 329-333
    • Horng, T.1    Barton, G.M.2    Flavell, R.A.3    Medzhitov, R.4
  • 7
    • 33646908228 scopus 로고    scopus 로고
    • Phosphoinositide-mediated adaptor recruitment controls toll-like receptor signaling
    • Kagan JC, Medzhitov R. Phosphoinositide-mediated adaptor recruitment controls toll-like receptor signaling. Cell 2006; 125: 943.
    • (2006) Cell , vol.125 , pp. 943
    • Kagan, J.C.1    Medzhitov, R.2
  • 8
    • 0043176281 scopus 로고    scopus 로고
    • Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
    • Yamamoto M, Sato S, Hemmi H et al. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 2003; 301: 640-643.
    • (2003) Science , vol.301 , pp. 640-643
    • Yamamoto, M.1    Sato, S.2    Hemmi, H.3
  • 9
    • 0042679529 scopus 로고    scopus 로고
    • Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
    • Hoebe K, Du X, Georgel P et al. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 2003; 424: 743-748.
    • (2003) Nature , vol.424 , pp. 743-748
    • Hoebe, K.1    Du, X.2    Georgel, P.3
  • 10
    • 0347146027 scopus 로고    scopus 로고
    • Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways
    • Hoebe K, Janssen EM, Kim SO et al. Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways. Nat Immunol 2003; 4: 1223-1229.
    • (2003) Nat Immunol , vol.4 , pp. 1223-1229
    • Hoebe, K.1    Janssen, E.M.2    Kim, S.O.3
  • 11
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001; 1: 135-145.
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 12
    • 0037094084 scopus 로고    scopus 로고
    • Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by toll-like receptor 4
    • Johnson GB, Brunn GJ, Kodaira Y, Platt JL. Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by toll-like receptor 4. J Immunol 2002; 168: 5233-5239.
    • (2002) J Immunol , vol.168 , pp. 5233-5239
    • Johnson, G.B.1    Brunn, G.J.2    Kodaira, Y.3    Platt, J.L.4
  • 13
    • 0037033364 scopus 로고    scopus 로고
    • Oligosaccharides of hyaluronan activate dendritic cells via toll-like receptor 4
    • Termeer C, Benedix F, Sleeman J et al. Oligosaccharides of hyaluronan activate dendritic cells via toll-like receptor 4. J Exp Med 2002; 195: 99-111.
    • (2002) J Exp Med , vol.195 , pp. 99-111
    • Termeer, C.1    Benedix, F.2    Sleeman, J.3
  • 14
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • Shi Y, Evans J, Rock K. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 2003; 425: 516-521.
    • (2003) Nature , vol.425 , pp. 516-521
    • Shi, Y.1    Evans, J.2    Rock, K.3
  • 16
    • 0034650427 scopus 로고    scopus 로고
    • Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
    • Ohashi K, Burkart V, Flohe S, Kolb H. Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 2000; 164: 558-561.
    • (2000) J Immunol , vol.164 , pp. 558-561
    • Ohashi, K.1    Burkart, V.2    Flohe, S.3    Kolb, H.4
  • 17
    • 23844482773 scopus 로고    scopus 로고
    • Heat shock proteins as endogenous adjuvants in sterile and septic inflammation
    • Quintana FJ, Cohen IR. Heat shock proteins as endogenous adjuvants in sterile and septic inflammation. J Immunol 2005; 175: 2777-2782.
    • (2005) J Immunol , vol.175 , pp. 2777-2782
    • Quintana, F.J.1    Cohen, I.R.2
  • 18
    • 0037097672 scopus 로고    scopus 로고
    • Cutting edge: The immunostimulatory activity of the lung surfactant protein-A involves toll-like receptor 4
    • Guillot L, Balloy V, McCormack FX, Golenbock DT, Chignard M, Si-Tahar M. Cutting edge: The immunostimulatory activity of the lung surfactant protein-A involves toll-like receptor 4. J Immunol 2002; 168: 5989-5992.
    • (2002) J Immunol , vol.168 , pp. 5989-5992
    • Guillot, L.1    Balloy, V.2    McCormack, F.X.3    Golenbock, D.T.4    Chignard, M.5    Si-Tahar, M.6
  • 19
    • 0343773922 scopus 로고    scopus 로고
    • Dendritic cells in transplantation - Friend or foe?
    • Lechler R, Ng WF, Steinman RM. Dendritic cells in transplantation - friend or foe? Immunity 2001; 14: 357-368.
    • (2001) Immunity , vol.14 , pp. 357-368
    • Lechler, R.1    Ng, W.F.2    Steinman, R.M.3
  • 20
    • 0037974914 scopus 로고    scopus 로고
    • Critical role of the toll-like receptor signal adaptor protein MyD88 in acute allograft rejection
    • Goldstein DR, Tesar BM, Akira S, Lakkis FG. Critical role of the toll-like receptor signal adaptor protein MyD88 in acute allograft rejection. J Clin Invest 2003; 111: 1571-1578.
    • (2003) J Clin Invest , vol.111 , pp. 1571-1578
    • Goldstein, D.R.1    Tesar, B.M.2    Akira, S.3    Lakkis, F.G.4
  • 21
    • 4344703413 scopus 로고    scopus 로고
    • TH1 immune responses to fully mhc mismatched allografts are diminished in the absence of myd88, a toll like receptor signal adaptor protein
    • Tesar BM, Zhang J, Li Q, Goldstein DR. TH1 immune responses to fully mhc mismatched allografts are diminished in the absence of myd88, a toll like receptor signal adaptor protein. Am J Transplant 2004; 4: 1429-1439.
    • (2004) Am J Transplant , vol.4 , pp. 1429-1439
    • Tesar, B.M.1    Zhang, J.2    Li, Q.3    Goldstein, D.R.4
  • 23
    • 0025313915 scopus 로고
    • Hyaluronic acid accumulation and redistribution in rejecting rat kidney graft
    • Hallgren R, Gerdin B, Tufverson T. Hyaluronic acid accumulation and redistribution in rejecting rat kidney graft. J Exp Med 1990; 171: 2063-2076.
    • (1990) J Exp Med , vol.171 , pp. 2063-2076
    • Hallgren, R.1    Gerdin, B.2    Tufverson, T.3
  • 24
    • 0029047394 scopus 로고
    • Expression of stress proteins and lymphocyte reactivity in heterotopic cardiac allografts undergoing cellular rejection
    • Qian J, Moliterno R, Donovan-Peluso MA et al. Expression of stress proteins and lymphocyte reactivity in heterotopic cardiac allografts undergoing cellular rejection. Transpl Immunol 1995; 3: 114-123.
    • (1995) Transpl Immunol , vol.3 , pp. 114-123
    • Qian, J.1    Moliterno, R.2    Donovan-Peluso, M.A.3
  • 25
    • 0033608987 scopus 로고    scopus 로고
    • The 60-kDa heat shock protein modulates allograft rejection
    • Birk OS, Gur SL, Elias D et al. The 60-kDa heat shock protein modulates allograft rejection. Proc Natl Acad Sci U S A 1999; 96: 5159-5163.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5159-5163
    • Birk, O.S.1    Gur, S.L.2    Elias, D.3
  • 26
    • 0033200301 scopus 로고    scopus 로고
    • Synthesis and selective cytotoxicity of a hyaluronic acid-antitumor bioconjugate
    • Luo Y, Preswitch GD. Synthesis and selective cytotoxicity of a hyaluronic acid-antitumor bioconjugate. Bioconjug Chem 1999; 103: 755-756.
    • (1999) Bioconjug Chem , vol.103 , pp. 755-756
    • Luo, Y.1    Preswitch, G.D.2
  • 27
    • 4644257453 scopus 로고    scopus 로고
    • Direct antigen presentation by a xenograft induces immunity independently of secondary lymphoid organs
    • Tesar BM, Chalasani G, Smith-Diggs L, Baddoura FK, Lakkis FG, Goldstein DR. Direct antigen presentation by a xenograft induces immunity independently of secondary lymphoid organs. J Immunol 2004; 173: 4377-4386.
    • (2004) J Immunol , vol.173 , pp. 4377-4386
    • Tesar, B.M.1    Chalasani, G.2    Smith-Diggs, L.3    Baddoura, F.K.4    Lakkis, F.G.5    Goldstein, D.R.6
  • 29
    • 0027428721 scopus 로고
    • A working formulation for the standardization of nomenclature and for clinical staging of chronic dysfunction in lung allografts
    • International Society for Heart and Lung Transplantation
    • Cooper JDBM, Egan T, Hertz MI et al. A working formulation for the standardization of nomenclature and for clinical staging of chronic dysfunction in lung allografts. International Society for Heart and Lung Transplantation. J Heart Lung Transplant 1993; 12: 713-716.
    • (1993) J Heart Lung Transplant , vol.12 , pp. 713-716
    • Cooper, J.D.B.M.1    Egan, T.2    Hertz, M.I.3
  • 30
    • 0037023364 scopus 로고    scopus 로고
    • Resolution of lung inflammation by CD44
    • Teder P, Vandivier RW, Jiang D et al. Resolution of lung inflammation by CD44. Science 2002; 296: 155-158.
    • (2002) Science , vol.296 , pp. 155-158
    • Teder, P.1    Vandivier, R.W.2    Jiang, D.3
  • 31
    • 0036467505 scopus 로고    scopus 로고
    • The role of chemokines in linking innate and adaptive immunity
    • Luster AD. The role of chemokines in linking innate and adaptive immunity. Curr Opin Immunol 2002; 14: 129-135.
    • (2002) Curr Opin Immunol , vol.14 , pp. 129-135
    • Luster, A.D.1
  • 32
    • 30744462300 scopus 로고    scopus 로고
    • Regulation of lung injury and repair by toll-like receptors and hyaluronan
    • Jiang D, Liang J, Fan J et al. Regulation of lung injury and repair by toll-like receptors and hyaluronan. Nat Med 2005; 11: 1173-1179.
    • (2005) Nat Med , vol.11 , pp. 1173-1179
    • Jiang, D.1    Liang, J.2    Fan, J.3
  • 33
    • 0141506128 scopus 로고    scopus 로고
    • The role of innate immunity in acute allograft rejection after lung transplantation
    • Palmer SM, Burch LH, Davis RD et al. The role of innate immunity in acute allograft rejection after lung transplantation. Am J Respir Crit Care Med 2003; 168: 628-632.
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 628-632
    • Palmer, S.M.1    Burch, L.H.2    Davis, R.D.3
  • 34
    • 0037080938 scopus 로고    scopus 로고
    • Manipulation of dendritic cells for tolerance induction in transplantation and autoimmune disease
    • Lu L, Thomson AW. Manipulation of dendritic cells for tolerance induction in transplantation and autoimmune disease. Transplantation 2002; 73 (1 Suppl): S19-S22.
    • (2002) Transplantation , vol.73 , Issue.1 SUPPL.
    • Lu, L.1    Thomson, A.W.2
  • 35
    • 20944443148 scopus 로고    scopus 로고
    • Organ transplantation - How much of the promise has been realized?
    • Lechler R, Sykes M, Thomson A, Turka L. Organ transplantation - how much of the promise has been realized? Nat Med 2005; 11: 605-613.
    • (2005) Nat Med , vol.11 , pp. 605-613
    • Lechler, R.1    Sykes, M.2    Thomson, A.3    Turka, L.4
  • 36
    • 19344364971 scopus 로고    scopus 로고
    • Decay-accelerating factor modulates induction of T cell immunity
    • Heeger PS, Lalli PN, Lin F et al. Decay-accelerating factor modulates induction of T cell immunity. J Exp Med 2005; 201: 1523-1530.
    • (2005) J Exp Med , vol.201 , pp. 1523-1530
    • Heeger, P.S.1    Lalli, P.N.2    Lin, F.3
  • 38
    • 0033608809 scopus 로고    scopus 로고
    • Immunomodulatory functions of hyaluronate in the LEW-to-F344 model of chronic cardiac allograft rejection
    • Knoflach A, Magee C, Denton MD et al. Immunomodulatory functions of hyaluronate in the LEW-to-F344 model of chronic cardiac allograft rejection. Transplantation 1999; 67: 909-914.
    • (1999) Transplantation , vol.67 , pp. 909-914
    • Knoflach, A.1    Magee, C.2    Denton, M.D.3
  • 39
    • 0035875835 scopus 로고    scopus 로고
    • Heat shock proteins, anti-heat shock protein reactivity and allograft rejection
    • Pockley AG. Heat shock proteins, anti-heat shock protein reactivity and allograft rejection. Transplantation 2001; 71: 1503-1507.
    • (2001) Transplantation , vol.71 , pp. 1503-1507
    • Pockley, A.G.1
  • 40
    • 0031900572 scopus 로고    scopus 로고
    • Increased expression of HDJ-2 (heat shock protein 40) and heat shock protein 70 in biopsy specimens of transplanted human lungs
    • Rizzo M, Alevy YG, Sundaresan S et al. Increased expression of HDJ-2 (heat shock protein 40) and heat shock protein 70 in biopsy specimens of transplanted human lungs. J Heart Lung Transplant 1998; 17: 241-249.
    • (1998) J Heart Lung Transplant , vol.17 , pp. 241-249
    • Rizzo, M.1    Alevy, Y.G.2    Sundaresan, S.3
  • 41
    • 0031194532 scopus 로고    scopus 로고
    • Heat shock protein 70 expression in native and heterotopically transplanted rat hearts
    • Mehta NK, Carroll M, Sykes DE et al. Heat shock protein 70 expression in native and heterotopically transplanted rat hearts. J Surg Res 1997; 70: 151-155.
    • (1997) J Surg Res , vol.70 , pp. 151-155
    • Mehta, N.K.1    Carroll, M.2    Sykes, D.E.3
  • 42
    • 0034054218 scopus 로고    scopus 로고
    • Blocking of CD44-hyaluronic acid interaction prolongs rat allograft survival
    • Zhang W, Gao L, Qi S et al. Blocking of CD44-hyaluronic acid interaction prolongs rat allograft survival. Transplantation 2000; 27: 665-667.
    • (2000) Transplantation , vol.27 , pp. 665-667
    • Zhang, W.1    Gao, L.2    Qi, S.3
  • 44
    • 0346024195 scopus 로고    scopus 로고
    • Role of CD44 and hyaluronic acid (HA) in activation of alloreactive and antigen-specific T cells by bone marrow-derived dendritic cells
    • Do Y, Nagarkatti PS, Nagarkatti M. Role of CD44 and hyaluronic acid (HA) in activation of alloreactive and antigen-specific T cells by bone marrow-derived dendritic cells. J Immunother 2004; 27: 1-12.
    • (2004) J Immunother , vol.27 , pp. 1-12
    • Do, Y.1    Nagarkatti, P.S.2    Nagarkatti, M.3
  • 45
    • 0038299308 scopus 로고    scopus 로고
    • HSP70.1 and 70.3 are required for late-phase protection induced by ischemic preconditioning of mouse hearts
    • Hampton CR, Shimamoto A, Rothnie CL et al. HSP70.1 and 70.3 are required for late-phase protection induced by ischemic preconditioning of mouse hearts. Am J Physiol Heart Circ Physiol 2003; 285: H866-H874.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Hampton, C.R.1    Shimamoto, A.2    Rothnie, C.L.3
  • 46
    • 0034254204 scopus 로고    scopus 로고
    • Phenotypic and functional maturation of dendritic cells mediated by heparan sulfate
    • Kodaira Y, Nair SK, Wrenshall LE, Gilboa E, Platt JL. Phenotypic and functional maturation of dendritic cells mediated by heparan sulfate. J Immunol 2000; 165: 1599-1604.
    • (2000) J Immunol , vol.165 , pp. 1599-1604
    • Kodaira, Y.1    Nair, S.K.2    Wrenshall, L.E.3    Gilboa, E.4    Platt, J.L.5
  • 47
    • 0034663808 scopus 로고    scopus 로고
    • Oligosaccharides of hyaluronan are potent activators of dendritic cells
    • Termeer CC, Hennies J, Voith U et al. Oligosaccharides of hyaluronan are potent activators of dendritic cells. J Immunol 2000; 165 (4): 1863-1870.
    • (2000) J Immunol , vol.165 , Issue.4 , pp. 1863-1870
    • Termeer, C.C.1    Hennies, J.2    Voith, U.3
  • 48
    • 0029952227 scopus 로고    scopus 로고
    • Hyaluronan fragments activate an NF-kappa B/I-kappa B alpha autoregulatory loop in murine macrophages
    • Noble PW, McKee CM, Cowman M, Shin HS. Hyaluronan fragments activate an NF-kappa B/I-kappa B alpha autoregulatory loop in murine macrophages. J Exp Med 1996; 183: 2373-2378.
    • (1996) J Exp Med , vol.183 , pp. 2373-2378
    • Noble, P.W.1    McKee, C.M.2    Cowman, M.3    Shin, H.S.4
  • 49
    • 23944489407 scopus 로고    scopus 로고
    • Selected toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
    • Napolitani G, Rinaldi A, Bertoni F, Sallusto F, Lanzavecchia A. Selected toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat Immunol 2005; 6: 769-776.
    • (2005) Nat Immunol , vol.6 , pp. 769-776
    • Napolitani, G.1    Rinaldi, A.2    Bertoni, F.3    Sallusto, F.4    Lanzavecchia, A.5
  • 50
    • 0034654349 scopus 로고    scopus 로고
    • Vigorous allograft rejection in the absence of danger
    • Bingaman AW, Ha J, Waitze S-Y et al. Vigorous allograft rejection in the absence of danger. J Immunol 2000; 164: 3065-3071.
    • (2000) J Immunol , vol.164 , pp. 3065-3071
    • Bingaman, A.W.1    Ha, J.2    Waitze, S.-Y.3
  • 51
    • 2942530583 scopus 로고    scopus 로고
    • The allograft defines the type of rejection (acute versus chronic) in the face of an established effector immune response
    • Chalasani G, Li Q, Konieczny BT et al. The allograft defines the type of rejection (acute versus chronic) in the face of an established effector immune response. J Immunol 2004; 172: 7813-7820.
    • (2004) J Immunol , vol.172 , pp. 7813-7820
    • Chalasani, G.1    Li, Q.2    Konieczny, B.T.3
  • 53
    • 0017313785 scopus 로고
    • Listeria sepsis immediately preceding renal transplant rejection
    • Finkelstein FO, Bastl C, Schiff M, Siegel NJ. Listeria sepsis immediately preceding renal transplant rejection. JAMA 1976; 235: 844-845.
    • (1976) JAMA , vol.235 , pp. 844-845
    • Finkelstein, F.O.1    Bastl, C.2    Schiff, M.3    Siegel, N.J.4
  • 54
    • 0017255482 scopus 로고
    • Virus infections and acute renal transplant rejection
    • Gabriel R, Selwyn S, Brown D et al. Virus infections and acute renal transplant rejection. Nephron 1976; 16: 282-286.
    • (1976) Nephron , vol.16 , pp. 282-286
    • Gabriel, R.1    Selwyn, S.2    Brown, D.3
  • 55
    • 0015263590 scopus 로고
    • The survival of skin allografts and xenografts in germ-free mice
    • Smith C, Pilgrim H, Steinmuller D. The survival of skin allografts and xenografts in germ-free mice. Transplantation 1972; 13: 38-41.
    • (1972) Transplantation , vol.13 , pp. 38-41
    • Smith, C.1    Pilgrim, H.2    Steinmuller, D.3
  • 56
    • 33644782017 scopus 로고    scopus 로고
    • New cellular and molecular immune pathways in ischemia/reperfusion injury
    • Boros P, Bromberg JS. New cellular and molecular immune pathways in ischemia/reperfusion injury. Am J Transplant 2006; 6: 652-658.
    • (2006) Am J Transplant , vol.6 , pp. 652-658
    • Boros, P.1    Bromberg, J.S.2
  • 57
    • 10344264453 scopus 로고    scopus 로고
    • Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via ifn regulatory factor 3-dependent myd88-independent pathway
    • Zhai Y, Shen X-D, O'Connell R et al. Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via ifn regulatory factor 3-dependent myd88-independent pathway. J Immunol 2004; 173: 7115-7119.
    • (2004) J Immunol , vol.173 , pp. 7115-7119
    • Zhai, Y.1    Shen, X.-D.2    O'Connell, R.3
  • 58
    • 0242624622 scopus 로고    scopus 로고
    • TRAM is specifically involved in the toll-like receptor 4-mediated MyD88-independent signaling pathway
    • Yamamoto M, Sato S, Hemmi H et al. TRAM is specifically involved in the toll-like receptor 4-mediated MyD88-independent signaling pathway. Nat Immunol 2003; 4: 1144-1150.
    • (2003) Nat Immunol , vol.4 , pp. 1144-1150
    • Yamamoto, M.1    Sato, S.2    Hemmi, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.