Indoleamine-2,3-Dioxygenase/Kynurenine Pathway as a Potential Pharmacological Target to Treat Depression Associated with Diabetes

Molecular Neurobiology

Volumn 53, Issue 10, 2016, Pages 6997-7009

  da Silva Dias, Isabella Caroline ^a   Carabelli, Bruno ^a   Ishii, Daniela Kaori ^a   de Morais, Helen ^a   de Carvalho, Milene Cristina ^b   Rizzo de Souza, Luiz E ^a   Zanata, Silvio M ^a   Brandão, Marcus Lira ^b   Cunha, Thiago Mattar ^b   Ferraz, Anete Curte ^a   Cunha, Joice Maria ^a   Zanoveli, Janaina Menezes ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Depression; Hippocampus; Indoleamine 2,3 dioxygenase inflammation; Serotonin; Streptozotocin

Indexed keywords

1 METHYLTRYPTOPHAN; ANTIDEPRESSANT AGENT; BRAIN PROTEIN; FLUOXETINE; IBUPROFEN; INDOLEAMINE 2,3 DIOXYGENASE; INDOLEAMINE 2,3 DIOXYGENASE INHIBITOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; KYNURENINE; MINOCYCLINE; NORADRENALIN; SEROTONIN; TRYPTOPHAN DERIVATIVE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; 1-METHYLTRYPTOPHAN; AUTACOID; CYTOKINE; ENZYME INHIBITOR; TRYPTOPHAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPRESSION; DIABETES MELLITUS; DISEASE ASSOCIATION; DRUG EFFECT; DRUG TARGETING; FORCED SWIM TEST; HIPPOCAMPUS; MALE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; ANIMAL BEHAVIOR; ANTAGONISTS AND INHIBITORS; BLOOD; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; GLUCOSE BLOOD LEVEL; METABOLISM; MOLECULARLY TARGETED THERAPY; MOTOR ACTIVITY; PATHOLOGY; PSYCHOLOGY; SWIMMING; WEIGHT GAIN; WISTAR RAT;

ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; BLOOD GLUCOSE; CYTOKINES; DEPRESSION; DIABETES MELLITUS, EXPERIMENTAL; ENZYME INHIBITORS; FLUOXETINE; HIPPOCAMPUS; IBUPROFEN; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INFLAMMATION MEDIATORS; KYNURENINE; MALE; MINOCYCLINE; MOLECULAR TARGETED THERAPY; MOTOR ACTIVITY; NOREPINEPHRINE; RATS, WISTAR; SEROTONIN; SWIMMING; TRYPTOPHAN; WEIGHT GAIN;

EID: 84949960938     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9617-0     Document Type: Article

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