Effects of aspirin on immobile behavior and endocrine and immune changes in the forced swimming test: Comparison to fluoxetine and imipramine

Pharmacology Biochemistry and Behavior

Volumn 124, Issue , 2014, Pages 361-366

  Guan, Xi Ting ^a,b   Shao, Feng ^c   Xie, Xi ^a,b   Chen, Lin ^d   Wang, Weiwen ^b  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^b INSTITUTE OF PSYCHOLOGY   (China)

^c PEKING UNIVERSITY   (China)

^d UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Antidepressant; Aspirin; Corticosterone; Forced swimming test; IL 6; TNF

Indexed keywords

ACETYLSALICYLIC ACID; CORTICOSTERONE; FLUOXETINE; IMIPRAMINE; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; ANTIDEPRESSANT AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DEPRESSION; DRUG EFFECT; DRUG MEGADOSE; ENDOCRINE SYSTEM; ENZYME LINKED IMMUNOSORBENT ASSAY; FORCED SWIM TEST; IMMOBILITY; IMMUNE SYSTEM; LOCOMOTION; LOW DRUG DOSE; MALE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; ANIMAL; ANIMAL BEHAVIOR; BLOOD; COMPARATIVE STUDY; DRUG EFFECTS; ENDOCRINE GLAND; SPRAGUE DAWLEY RAT; SWIMMING;

ANIMALS; ANTIDEPRESSIVE AGENTS; ASPIRIN; BEHAVIOR, ANIMAL; CORTICOSTERONE; ENDOCRINE GLANDS; FLUOXETINE; IMIPRAMINE; IMMUNE SYSTEM; INTERLEUKIN-6; MALE; RATS; RATS, SPRAGUE-DAWLEY; SWIMMING; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84904868880     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2014.07.002     Document Type: Article

References (75)

1. O.M. Abdel-Salam, S.M. Nofal, and S.M. El-Shenawy Evaluation of the anti-inflammatory and anti-nociceptive effects of different antidepressants in the rat Pharmacol Res 48 2 2003 157 165 (Pubitemid 36683164)
2. O.M. Abdel-Salam, A.R. Baiuomy, and M.S. Arbid Studies on the anti-inflammatory effect of fluoxetine in the rat Pharmacol Res 49 2 2004 119 131 (Pubitemid 37485709)
3. R. Amann, and B.A. Peskar Anti-inflammatory effects of aspirin and sodium salicylate Eur J Pharmacol 447 1 2002 1 9 (Pubitemid 34775215)
4. H. Anisman, A.V. Ravindran, J. Griffiths, and Z. Merali Endocrine and cytokine correlates of major depression and dysthymia with typical or atypical features Mol Psychiatry 4 2 1999 182 188 (Pubitemid 29163982)
5. F. Borsini, and A. Meli Is the forced swimming test a suitable model for revealing antidepressant activity? Psychopharmacology (Berl) 94 2 1988 147 160 (Pubitemid 18040687)
6. N. Brunello, S. Alboni, G. Capone, C. Benatti, J.M. Blom, and F. Tascedda et al. Acetylsalicylic acid accelerates the antidepressant effect of fluoxetine in the chronic escape deficit model of depression Int Clin Psychopharmacol 21 4 2006 219 225 (Pubitemid 43740299)
7. N. Castanon, B.E. Leonard, P.J. Neveu, and R. Yirmiya Effects of antidepressants on cytokine production and actions Brain Behav Immun 16 5 2002 569 574 (Pubitemid 35333736)
8. F. Cavagnini, A. Di Landro, C. Maraschini, C. Invitti, and M.L. Pinto Effect of two prostaglandin synthesis inhibitors, indomethacin and acetylsalicylic acid, on plasma ACTH and cortisol levels in man Acta Endocrinol (Copenh) 91 4 1979 666 673 (Pubitemid 10225456)
9. B.G. Charlton A model for self-treatment of four sub-types of symptomatic 'depression' using non-prescription agents: neuroticism (anxiety and emotional instability); malaise (fatigue and painful symptoms); demotivation (anhedonia) and seasonal affective disorder 'SAD' Med Hypotheses 72 1 2009 1 7
10. S. Chourbaji, A. Urani, I. Inta, C. Sanchis-Segura, C. Brandwein, and M. Zink et al. IL-6 knockout mice exhibit resistance to stress-induced development of depression-like behaviors Neurobiol Dis 23 3 2006 587 594 (Pubitemid 44234095)
11. A.S. Clarke, G.W. Kraemer, and D.J. Kupfer Effects of rearing condition on HPA axis response to fluoxetine and desipramine treatment over repeated social separations in young rhesus monkeys Psychiatry Res 79 2 1998 91 104 (Pubitemid 28308483)
12. J.F. Coetzee, R. Gehring, A.C. Bettenhausen, B.V. Lubbers, S.E. Toerber, and D.U. Thomson et al. Attenuation of acute plasma cortisol response in calves following intravenous sodium salicylate administration prior to castration J Vet Pharmacol Ther 30 4 2007 305 313 (Pubitemid 47024879)
13. T.J. Connor, J.P. Kelly, and B.E. Leonard Forced swim test-induced neurochemical endocrine, and immune changes in the rat Pharmacol Biochem Behav 58 4 1997 961 967 (Pubitemid 28108203)
14. T.J. Connor, J.P. Kelly, and B.E. Leonard Forced swim test-induced endocrine and immune changes in the rat: effect of subacute desipramine treatment Pharmacol Biochem Behav 59 1 1998 171 177 (Pubitemid 28053695)
15. T.J. Connor, P. Kelliher, Y. Shen, A. Harkin, J.P. Kelly, and B.E. Leonard Effect of subchronic antidepressant treatments on behavioral, neurochemical, and endocrine changes in the forced-swim test Pharmacol Biochem Behav 65 4 2000 591 597 (Pubitemid 30182501)
16. J.F. Cryan, A. Markou, and I. Lucki Assessing antidepressant activity in rodents: recent developments and future needs Trends Pharmacol Sci 23 5 2002 238 245 (Pubitemid 34465544)
17. J.F. Cryan, R.J. Valentino, and I. Lucki Assessing substrates underlying the behavioral effects of antidepressants using the modified rat forced swimming test Neurosci Biobehav Rev 29 4-5 2005 547 569 (Pubitemid 40755456)
18. J. De Cristobal, J.L. Madrigal, I. Lizasoain, P. Lorenzo, J.C. Leza, and M.A. Moro Aspirin inhibits stress-induced increase in plasma glutamate, brain oxidative damage and ATP fall in rats Neuroreport 13 2 2002 217 221 (Pubitemid 34169595)
19. M.J. Detke, M. Rickels, and I. Lucki Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants Psychopharmacology (Berl) 121 1 1995 66 72
20. G.E. Duncan, D.J. Knapp, S.W. Carson, and G.R. Breese Differential effects of chronic antidepressant treatment on swim stress- and fluoxetine-induced secretion of corticosterone and progesterone J Pharmacol Exp Ther 285 2 1998 579 587 (Pubitemid 28237436)
21. S.H. Ferreira, S. Moncada, and J.R. Vane Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs Br J Pharmacol 49 1 1973 86 97
22. A. Flugy, M. Gagliano, C. Cannizzaro, V. Novara, and G. Cannizzaro Antidepressant and anxiolytic effects of alprazolam versus the conventional antidepressant desipramine and the anxiolytic diazepam in the forced swim test in rats Eur J Pharmacol 214 2-3 1992 233 238
23. U.H. Frommberger, J. Bauer, P. Haselbauer, A. Fraulin, D. Riemann, and M. Berger Interleukin-6-(IL-6) plasma levels in depression and schizophrenia: comparison between the acute state and after remission Eur Arch Psychiatry Clin Neurosci 247 4 1997 228 233 (Pubitemid 27399827)
24. X.R. Gao, C.M. Adhikari, L.Y. Peng, X.G. Guo, Y.S. Zhai, and X.Y. He et al. Efficacy of different doses of aspirin in decreasing blood levels of inflammatory markers in patients with cardiovascular metabolic syndrome J Pharm Pharmacol 61 11 2009 1505 1510
25. A.G. Gutierrez-Garcia, and C.M. Contreras Stressors can affect immobility time and response to imipramine in the rat forced swim test Pharmacol Biochem Behav 91 4 2009 542 548
26. J.B. Halter, and S.A. Metz Sodium salicylate augments the plasma adrenocorticotropin and cortisol responses to insulin hypoglycemia in man J Clin Endocrinol Metab 54 1 1982 120 127
27. C. Hartel, J. von Puttkamer, F. Gallner, T. Strunk, and C. Schultz Dose-dependent immunomodulatory effects of acetylsalicylic acid and indomethacin in human whole blood: potential role of cyclooxygenase-2 inhibition Scand J Immunol 60 4 2004 412 420 (Pubitemid 39331497)
28. G.I. Hockings, J.E. Grice, G.V. Crosbie, M.M. Walters, A.J. Jackson, and R.V. Jackson Aspirin increases the human hypothalamic-pituitary-adrenal axis response to naloxone stimulation J Clin Endocrinol Metab 77 2 1993 404 408 (Pubitemid 23230048)
29. I. Ikonomidis, F. Andreotti, E. Economou, C. Stefanadis, P. Toutouzas, and P. Nihoyannopoulos Increased proinflammatory cytokines in patients with chronic stable angina and their reduction by aspirin Circulation 100 8 1999 793 798 (Pubitemid 29398875)
30. S.A. Johnson, N.M. Fournier, and L.E. Kalynchuk Effect of different doses of corticosterone on depression-like behavior and HPA axis responses to a novel stressor Behav Brain Res 168 2 2006 280 288 (Pubitemid 43201945)
31. A.M. Joussen, V. Poulaki, N. Mitsiades, B. Kirchhof, K. Koizumi, and S. Döhmen et al. Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-α suppression FASEB J 16 3 2002 438 440
32. E.M. Jutkiewicz, S.K. Wood, H. Houshyar, L.W. Hsin, K.C. Rice, and J.H. Woods The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919, in the forced swim test and on swim-induced increases in adrenocorticotropin in rats Psychopharmacology (Berl) 180 2 2005 215 223 (Pubitemid 40909666)
33. M.P. Kaster, V.M. Gadotti, J.B. Calixto, A.R. Santos, and A.L. Rodrigues Depressive-like behavior induced by tumor necrosis factor-alpha in mice Neuropharmacology 62 1 2012 419 426
34. P. Kelliher, J.P. Kelly, B.E. Leonard, and C. Sánchez Effects of acute and chronic administration of selective monoamine re-uptake inhibitors in the rat forced swim test Psychoneuroendocrinology 28 3 2003 332 347 (Pubitemid 36164952)
35. J.G. Kelton, J. Hirsh, C.J. Carter, and M.R. Buchanan Thrombogenic effect of high-dose aspirin in rabbits. Relationship to inhibition of vessel wall synthesis of prostaglandin I2-like activity J Clin Invest 62 4 1978 892 895 (Pubitemid 9032272)
36. M.W. Ketterer, J. Brymer, K. Rhoads, P. Kraft, and W.R. Lovallo Is aspirin, as used for antithrombosis, an emotion-modulating agent? J Psychosom Res 40 1 1996 53 58 (Pubitemid 26059538)
37. S.K. Kulkarni, and A. Dhir Effect of various classes of antidepressants in behavioral paradigms of despair Prog Neuropsychopharmacol Biol Psychiatry 31 6 2007 1248 1254 (Pubitemid 47081311)
38. J. Liu, X. Li, L. Wang, Y. Dong, H. Han, and G. Liu Effects of salicylate on serotoninergic activities in rat inferior colliculus and auditory cortex Hear Res 175 1-2 2003 45 53
39. I. Lucki The forced swimming test as a model for core and component behavioral effects of antidepressant drugs Behav Pharmacol 8 6-7 1997 523 532 (Pubitemid 27504702)
40. M. Maes Evidence for an immune response in major depression: a review and hypothesis Prog Neuropsychopharmacol Biol Psychiatry 19 1 1995 11 38
41. M. Maes Major depression and activation of the inflammatory response system Adv Exp Med Biol 461 1999 25 46
42. S. Mastbergen, F. Lafeber, and J. Bijlsma Selective COX-2 inhibition prevents proinflammatory cytokine-induced cartilage damage Rheumatology 41 7 2002 801 808 (Pubitemid 34822964)
43. J. Mendlewicz, P. Kriwin, P. Oswald, D. Souery, S. Alboni, and N. Brunello Shortened onset of action of antidepressants in major depression using acetylsalicylic acid augmentation: a pilot open-label study Int Clin Psychopharmacol 21 4 2006 227 231 (Pubitemid 43740300)
44. C. Michel, P. Frankham, and M. Cabanac Salicylate as a partial inhibitor of emotional fever and body weight set-point in rats: behavioral and neuroendocrine study Physiol Behav 78 3 2003 357 363 (Pubitemid 36369708)
45. D. Michelson, E. Galliven, L. Hill, M. Demitrack, G. Chrousos, and P. Gold Chronic imipramine is associated with diminished hypothalamic-pituitary- adrenal axis responsivity in healthy humans J Clin Endocrinol Metab 82 8 1997 2601 2606 (Pubitemid 27337880)
46. S.J. Motivala, A. Sarfatti, L. Olmos, and M.R. Irwin Inflammatory markers and sleep disturbance in major depression Psychosom Med 67 2 2005 187 194 (Pubitemid 40410952)
47. E.J. Nye, G.I. Hockings, J.E. Grice, D.J. Torpy, M.M. Walters, and G.V. Crosbie et al. Aspirin inhibits vasopressin-induced hypothalamic-pituitary- adrenal activity in normal humans J Clin Endocrinol Metab 82 3 1997 812 817 (Pubitemid 27106593)
48. T.W. Pace, F. Hu, and A.H. Miller Cytokine-effects on glucocorticoid receptor function: relevance to glucocorticoid resistance and the pathophysiology and treatment of major depression Brain Behav Immun 21 1 2007 9 19 (Pubitemid 44872932)
49. J.A. Pasco, F.N. Jacka, L.J. Williams, M.J. Henry, G.C. Nicholson, and M.A. Kotowicz et al. Clinical implications of the cytokine hypothesis of depression: the association between use of statins and aspirin and the risk of major depression Psychother Psychosom 79 5 2010 323 325
50. J.L. Pike, and M.R. Irwin Dissociation of inflammatory markers and natural killer cell activity in major depressive disorder Brain Behav Immun 20 2 2006 169 174 (Pubitemid 43202082)
51. R.D. Porsolt, M. Le Pichon, and M. Jalfre Depression: a new animal model sensitive to antidepressant treatments Nature 266 5604 1977 730 732 (Pubitemid 8073804)
52. J. Przybylowski, K. Obodynski, C. Lewicki, J. Kuzniar, S. Zaborniak, and S. Drozd et al. The influence of aspirin on exercise-induced changes in adrenocorticotrophic hormone (ACTH), cortisol and aldosterone (ALD) concentrations Eur J Appl Physiol 89 2 2003 177 183 (Pubitemid 36747974)
53. X. Qi, W. Lin, J. Li, Y. Pan, and W. Wang The depressive-like behaviors are correlated with decreased phosphorylation of mitogen-activated protein kinases in rat brain following chronic forced swim stress Behav Brain Res 175 2 2006 233 240 (Pubitemid 44750226)
54. J.P. Reneric, and I. Lucki Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test Psychopharmacology (Berl) 136 2 1998 190 197 (Pubitemid 28137959)
55. J.P. Reneric, M. Bouvard, and L. Stinus In the rat forced swimming test, chronic but not subacute administration of dual 5-HT/NA antidepressant treatments may produce greater effects than selective drugs Behav Brain Res 136 2 2002 521 532 (Pubitemid 35333268)
56. J.M. Reul, I. Stec, M. Soder, and F. Holsboer Chronic treatment of rats with the antidepressant amitriptyline attenuates the activity of the hypothalamic-pituitary-adrenocortical system Endocrinology 133 1 1993 312 320 (Pubitemid 23206409)
57. J.M. Reul, M.S. Labeur, D.E. Grigoriadis, E.B. De Souza, and F. Holsboer Hypothalamic-pituitary-adrenocortical axis changes in the rat after long-term treatment with the reversible monoamine oxidase-A inhibitor moclobemide Neuroendocrinology 60 5 1994 509 519
58. J. Reynolds, T. Ignatowski, R. Sud, and R. Spengler An antidepressant mechanism of desipramine is to decrease tumor necrosis factor-[alpha] production culminating in increases in noradrenergic neurotransmission Neuroscience 133 2 2005 519 531 (Pubitemid 40726218)
59. G.J. Roth, and P.W. Majerus The mechanism of the effect of aspirin on human platelets. I. Acetylation of a particulate fraction protein J Clin Invest 56 3 1975 624 632
60. B. Sakic, J. Gauldie, J.A. Denburg, and H. Szechtman Behavioral effects of infection with IL-6 adenovector Brain Behav Immun 15 1 2001 25 42 (Pubitemid 33070867)
61. S. Sarkar, R.K. Chadda, N. Kumar, and R. Narang Anxiety and depression in patients with myocardial infarction: findings from a centre in India Gen Hosp Psychiatry 34 2 2011 160 166
62. F. Shao, J. Jin, Q. Meng, M. Liu, X. Xie, and W. Lin et al. Pubertal isolation alters latent inhibition and DA in nucleus accumbens of adult rats Physiol Behav 98 3 2009 251 257
63. B.B. Simen, C.H. Duman, A.A. Simen, and R.S. Duman TNFalpha signaling in depression and anxiety: behavioral consequences of individual receptor targeting Biol Psychiatry 59 9 2006 775 785
64. F. Tronche, C. Kellendonk, O. Kretz, P. Gass, K. Anlag, and P.C. Orban et al. Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety Nat Genet 23 1 1999 99 103 (Pubitemid 29418797)
65. J.R. Vane, and R.M. Botting The mechanism of action of aspirin Thromb Res 110 5-6 2003 255 258 (Pubitemid 37329821)
66. R. von Känel, B.M. Kudielka, P. Metzenthin, S. Helfricht, D. Preckel, and A. Haeberli et al. Aspirin, but not propranolol, attenuates the acute stress-induced increase in circulating levels of interleukin-6: a randomized, double-blind, placebo-controlled study Brain Behav Immun 22 2 2008 150 157 (Pubitemid 350299803)
67. Y. Wang, F. Yang, Y.F. Liu, F. Gao, and W. Jiang Acetylsalicylic acid as an augmentation agent in fluoxetine treatment resistant depressive rats Neurosci Lett 499 2 2011 74 79
68. J.L. Warner-Schmidt, K.E. Vanover, E.Y. Chen, J.J. Marshall, and P. Greengard Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans Proc Natl Acad Sci U S A 108 22 2011 9262 9267
69. S. Watson, K. Horton, S. Bulmer, J. Carlile, C. Corcoran, and P. Gallagher et al. Effect of aspirin on hypothalamic-pituitary-adrenal function and on neuropsychological performance in healthy adults: a pilot study Psychopharmacology (Berl) 205 1 2009 151 155
70. T.H. Wu, and C.H. Lin IL-6 mediated alterations on immobile behavior of rats in the forced swim test via ERK1/2 activation in specific brain regions Behav Brain Res 193 2 2008 183 191
71. Z. Xia, J.W. Depierre, and L. Nässberger Tricyclic antidepressants inhibit IL-6, IL-1 [beta] and TNF-[alpha] release in human blood monocytes and IL-2 and interferon-[gamma] in T cells Immunopharmacology 34 1 1996 27 37 (Pubitemid 26284175)
72. K. Yamada, R. Iida, Y. Miyamoto, K. Saito, K. Sekikawa, and M. Seishima et al. Neurobehavioral alterations in mice with a targeted deletion of the tumor necrosis factor-alpha gene: implications for emotional behavior J Neuroimmunol 111 1-2 2000 131 138
73. R. Yirmiya, Y. Pollak, M. Morag, A. Reichenberg, O. Barak, and R. Avitsur et al. Illness, cytokines, and depression Ann N Y Acad Sci 917 2000 478 487
74. E.A. Young, M. Altemus, J.F. Lopez, J.H. Kocsis, A.F. Schatzberg, and C. DeBattista et al. HPA axis activation in major depression and response to fluoxetine: a pilot study Psychoneuroendocrinology 29 9 2004 1198 1204 (Pubitemid 38829182)
75. E.P. Zorrilla, L. Luborsky, J.R. McKay, R. Rosenthal, A. Houldin, and A. Tax et al. The relationship of depression and stressors to immunological assays: a meta-analytic review Brain Behav Immun 15 3 2001 199 226 (Pubitemid 33070955)