Structural Changes and Aggregation Mechanisms for Anti-Streptavidin IgG1 at Elevated Concentration

Journal of Physical Chemistry B

Volumn 119, Issue 49, 2015, Pages 15150-15163

  Barnett, Gregory V ^a   Qi, Wei ^b   Amin, Samiul ^b   Lewis, E Neil ^b   Razinkov, Vladimir I ^c   Kerwin, Bruce A ^c   Liu, Yun ^a,d   Roberts, Christopher J ^a  

^a UNIVERSITY OF DELAWARE   (United States)

^b Malvern Biosciences Inc   (United States)

^c AMGEN INC   (United States)

^d NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGREGATES; CIRCULAR DICHROISM SPECTROSCOPY; DICHROISM; LIGHT SCATTERING; NEUTRON SCATTERING; PROTEINS; SUGAR (SUCROSE); ULTRAVIOLET SPECTROSCOPY;

DILUTE CONCENTRATIONS; ELECTROSTATIC REPULSION; ELEVATED CONCENTRATIONS; HIGHER-ORDER STRUCTURE; PROTEIN CONCENTRATIONS; PROTEIN-PROTEIN INTERACTIONS; STRUCTURAL PERTURBATION; UV CIRCULAR DICHROISM;

AGGLOMERATION;

IMMUNOGLOBULIN G; STREPTAVIDIN;

CHEMISTRY; CIRCULAR DICHROISM; IMMUNOLOGY; KINETICS; PROTEIN CONFORMATION; RAMAN SPECTROMETRY; ULTRAVIOLET SPECTROPHOTOMETRY;

CIRCULAR DICHROISM; IMMUNOGLOBULIN G; KINETICS; PROTEIN CONFORMATION; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTRUM ANALYSIS, RAMAN; STREPTAVIDIN;

EID: 84949568378     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/acs.jpcb.5b08748     Document Type: Article

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