메뉴 건너뛰기




Volumn 6, Issue NOV, 2015, Pages

Cytoglobin as a marker of hepatic stellate cell-derived myofibroblasts

Author keywords

Cytoglobin; Hypoxia; Liver fibrosis; Myofibroblast; Stellate cell

Indexed keywords

ALPHA CRYSTALLIN; ALPHA SMOOTH MUSCLE ACTIN; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CELL MARKER; CYTOGLOBIN; ELASTIN; FIBULIN; FIBULIN 2; GLIAL FIBRILLARY ACIDIC PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 84949564336     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2015.00329     Document Type: Review
Times cited : (22)

References (70)
  • 1
    • 77649168237 scopus 로고    scopus 로고
    • Distinct proteomic features of two fibrogenic liver cell populations: hepatic stellate cells and portal myofibroblasts
    • Bosselut, N., Housset, C., Marcelo, P., Rey, C., Burmester, T., Vinh, J., et al. (2010). Distinct proteomic features of two fibrogenic liver cell populations: hepatic stellate cells and portal myofibroblasts. Proteomics 10, 1017-1028. doi: 10.1002/pmic.200900257.
    • (2010) Proteomics , vol.10 , pp. 1017-1028
    • Bosselut, N.1    Housset, C.2    Marcelo, P.3    Rey, C.4    Burmester, T.5    Vinh, J.6
  • 2
    • 0036219963 scopus 로고    scopus 로고
    • Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues
    • Burmester, T., Ebner, B., Weich, B., and Hankeln, T. (2002). Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues. Mol. Biol. Evol. 19, 416-421. doi: 10.1093/oxfordjournals.molbev.a004096.
    • (2002) Mol. Biol. Evol , vol.19 , pp. 416-421
    • Burmester, T.1    Ebner, B.2    Weich, B.3    Hankeln, T.4
  • 3
    • 84902348270 scopus 로고    scopus 로고
    • Function and evolution of vertebrate globins
    • Burmester, T., and Hankeln, T. (2014). Function and evolution of vertebrate globins. Acta Physiol. 211, 501-514. doi: 10.1111/apha.12312.
    • (2014) Acta Physiol , vol.211 , pp. 501-514
    • Burmester, T.1    Hankeln, T.2
  • 4
    • 0036166579 scopus 로고    scopus 로고
    • Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers
    • Cassiman, D., Libbrecht, L., Desmet, V., Denef, C., and Roskams, T. (2002). Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers. J. Hepatol. 36, 200-209. doi: 10.1016/S0168-8278(01)00260-4.
    • (2002) J. Hepatol , vol.36 , pp. 200-209
    • Cassiman, D.1    Libbrecht, L.2    Desmet, V.3    Denef, C.4    Roskams, T.5
  • 5
    • 84904963044 scopus 로고    scopus 로고
    • Expression and biological role of cytoglobin in human ovarian cancer
    • Chen, H., Zhao, X., and Meng, T. (2014). Expression and biological role of cytoglobin in human ovarian cancer. Tumour Biol. 35, 6933-6939. doi: 10.1007/s13277-014-1941-x.
    • (2014) Tumour Biol , vol.35 , pp. 6933-6939
    • Chen, H.1    Zhao, X.2    Meng, T.3
  • 6
    • 78449240951 scopus 로고    scopus 로고
    • Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway
    • Choi, S. S., Syn, W. K., Karaca, G. F., Omenetti, A., Moylan, C. A., Witek, R. P., et al. (2010). Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway. J. Biol. Chem. 285, 36551-35560. doi: 10.1074/jbc. M110.168542.
    • (2010) J. Biol. Chem , vol.285 , pp. 36551-35560
    • Choi, S.S.1    Syn, W.K.2    Karaca, G.F.3    Omenetti, A.4    Moylan, C.A.5    Witek, R.P.6
  • 7
    • 84861147161 scopus 로고    scopus 로고
    • Hepatocyte-stellate cell cross-talk in the liver engenders a permissive inflammatory microenvironment that drives progression in hepatocellular carcinoma
    • Coulouarn, C., Corlu, A., Glaise, D., Guénon, I., Thorgeirsson, S. S., and Clément, B. (2012). Hepatocyte-stellate cell cross-talk in the liver engenders a permissive inflammatory microenvironment that drives progression in hepatocellular carcinoma. Cancer Res. 72, 2533-2542. doi: 10.1158/0008-5472.CAN-11-3317.
    • (2012) Cancer Res , vol.72 , pp. 2533-2542
    • Coulouarn, C.1    Corlu, A.2    Glaise, D.3    Guénon, I.4    Thorgeirsson, S.S.5    Clément, B.6
  • 8
    • 84865539649 scopus 로고    scopus 로고
    • Inhibition of the activation of hepatic stellate cells by arundic acid via the induction of cytoglobin
    • Cui, W., Wang, M., Maegawa, H., Teranishi, Y., and Kawada, N. (2012). Inhibition of the activation of hepatic stellate cells by arundic acid via the induction of cytoglobin. Biochem. Biophys. Res. Commun. 425, 642-648. doi: 10.1016/j.bbrc.2012.07.126.
    • (2012) Biochem. Biophys. Res. Commun , vol.425 , pp. 642-648
    • Cui, W.1    Wang, M.2    Maegawa, H.3    Teranishi, Y.4    Kawada, N.5
  • 9
    • 84926293598 scopus 로고    scopus 로고
    • Establishment and characterization of rat portal myofibroblast cell lines
    • Fausther, M., Goree, J. R., Lavoie, É. G., Graham, A. L., Sévigny, J., and Dranoff, J. A. (2015). Establishment and characterization of rat portal myofibroblast cell lines. PLoS ONE 10:e0121161. doi: 10.1371/journal.pone.0121161.
    • (2015) PLoS ONE , vol.10
    • Fausther, M.1    Goree, J.R.2    Lavoie, É.G.3    Graham, A.L.4    Sévigny, J.5    Dranoff, J.A.6
  • 10
    • 33750705253 scopus 로고    scopus 로고
    • Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death
    • Fordel, E., Thijs, L., Martinet, W., Lenjou, M., Laufs, T., Van Bockstaele, D., et al. (2006). Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death. Neurosci. Lett. 410, 146-151. doi: 10.1016/j.neulet.2006.09.027.
    • (2006) Neurosci. Lett , vol.410 , pp. 146-151
    • Fordel, E.1    Thijs, L.2    Martinet, W.3    Lenjou, M.4    Laufs, T.5    Van Bockstaele, D.6
  • 11
    • 33846968462 scopus 로고    scopus 로고
    • Neuroglobin and cytoglobin expression in mice. Evidence for a correlation with reactive oxygen species scavenging
    • Fordel, E., Thijs, L., Moens, L., and Dewilde, S. (2007). Neuroglobin and cytoglobin expression in mice. Evidence for a correlation with reactive oxygen species scavenging. FEBS J. 274, 1312-1317. doi: 10.1111/j.1742-4658.2007.05679.x.
    • (2007) FEBS J , vol.274 , pp. 1312-1317
    • Fordel, E.1    Thijs, L.2    Moens, L.3    Dewilde, S.4
  • 12
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver
    • Friedman, S. L. (2008). Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol. Rev. 88, 125-172. doi: 10.1152/physrev.00013.2007.
    • (2008) Physiol. Rev , vol.88 , pp. 125-172
    • Friedman, S.L.1
  • 13
    • 84899545002 scopus 로고    scopus 로고
    • Melanoma transition is frequently accompanied by a loss of cytoglobin expression in melanocytes: a novel expression site of cytoglobin
    • Fujita, Y., Koinuma, S., De Velasco, M. A., Bolz, J., Togashi, Y., Terashima, M., et al. (2014). Melanoma transition is frequently accompanied by a loss of cytoglobin expression in melanocytes: a novel expression site of cytoglobin. PLoS ONE 9:e94772. doi: 10.1371/journal.pone.0094772.
    • (2014) PLoS ONE , vol.9
    • Fujita, Y.1    Koinuma, S.2    De Velasco, M.A.3    Bolz, J.4    Togashi, Y.5    Terashima, M.6
  • 14
    • 0015225464 scopus 로고
    • Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction
    • Gabbiani, G., Ryan, G. B., and Majno, G. (1971). Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Experientia 27, 549-550. doi: 10.1007/BF02147594.
    • (1971) Experientia , vol.27 , pp. 549-550
    • Gabbiani, G.1    Ryan, G.B.2    Majno, G.3
  • 15
    • 33947143078 scopus 로고    scopus 로고
    • Gene expression during chemically induced liver fibrosis: effect of halofuginone on TGF-beta signaling
    • Gnainsky, Y., Kushnirsky, Z., Bilu, G., Hagai, Y., Genina, O., Volpin, H., et al. (2007). Gene expression during chemically induced liver fibrosis: effect of halofuginone on TGF-beta signaling. Cell Tissue Res. 328, 153-166. doi: 10.1007/s00441-006-0330-1.
    • (2007) Cell Tissue Res , vol.328 , pp. 153-166
    • Gnainsky, Y.1    Kushnirsky, Z.2    Bilu, G.3    Hagai, Y.4    Genina, O.5    Volpin, H.6
  • 16
    • 0017644132 scopus 로고
    • Myofibroblasts in hepatic schistosomal fibrosis
    • Grimaud, J. A., and Borojevic, R. (1977). Myofibroblasts in hepatic schistosomal fibrosis. Experientia 33, 890-892. doi: 10.1007/BF01951264.
    • (1977) Experientia , vol.33 , pp. 890-892
    • Grimaud, J.A.1    Borojevic, R.2
  • 17
    • 35348964146 scopus 로고    scopus 로고
    • Study of the hypoxia-dependent regulation of human CYGB gene
    • Guo, X., Philipsen, S., and Tan-Un, K. C. (2007). Study of the hypoxia-dependent regulation of human CYGB gene. Biochem. Biophys. Res. Commun. 364, 145-150. doi: 10.1016/j.bbrc.2007.09.108.
    • (2007) Biochem. Biophys. Res. Commun , vol.364 , pp. 145-150
    • Guo, X.1    Philipsen, S.2    Tan-Un, K.C.3
  • 18
    • 33745919556 scopus 로고    scopus 로고
    • Characterization of human cytoglobin gene promoter region
    • Guo, X., Philipsen, S., and Tan-Un, K. C. (2006). Characterization of human cytoglobin gene promoter region. Biochim. Biophys. Acta 1759, 208-215. doi: 10.1016/j.bbaexp.2006.04.002.
    • (2006) Biochim. Biophys. Acta , vol.1759 , pp. 208-215
    • Guo, X.1    Philipsen, S.2    Tan-Un, K.C.3
  • 19
    • 81155133936 scopus 로고    scopus 로고
    • Cytoglobin exhibits anti-fibrosis activity on liver in vivo and in vitro
    • He, X., Lv, R., Wang, K., Huang, X., Wu, W., Yin, L., et al. (2011). Cytoglobin exhibits anti-fibrosis activity on liver in vivo and in vitro. Protein J. 30, 437-446. doi: 10.1007/s10930-011-9340-2.
    • (2011) Protein J , vol.30 , pp. 437-446
    • He, X.1    Lv, R.2    Wang, K.3    Huang, X.4    Wu, W.5    Yin, L.6
  • 20
    • 84899478253 scopus 로고    scopus 로고
    • Methylation analysis in spontaneous sputum for lung cancer diagnosis
    • Hubers, A. J., van der Drift, M. A., Prinsen, C. F., Witte, B. I., Wang, Y., Shivapurkar, N., et al. (2014). Methylation analysis in spontaneous sputum for lung cancer diagnosis. Lung Cancer 84, 127-133. doi: 10.1016/j.lungcan.2014.01.019.
    • (2014) Lung Cancer , vol.84 , pp. 127-133
    • Hubers, A.J.1    van der Drift, M.A.2    Prinsen, C.F.3    Witte, B.I.4    Wang, Y.5    Shivapurkar, N.6
  • 22
    • 20744441669 scopus 로고    scopus 로고
    • Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2
    • Jhandier, M. N., Kruglov, E. A., Lavoie, E. G., Sévigny, J., and Dranoff, J. A. (2005). Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2. J. Biol. Chem. 280, 22986-22992. doi: 10.1074/jbc. M412371200.
    • (2005) J. Biol. Chem , vol.280 , pp. 22986-22992
    • Jhandier, M.N.1    Kruglov, E.A.2    Lavoie, E.G.3    Sévigny, J.4    Dranoff, J.A.5
  • 23
    • 0035816696 scopus 로고    scopus 로고
    • Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells
    • Kawada, N., Kristensen, D. B., Asahina, K., Nakatani, K., Minamiyama, Y., Seki, S., et al. (2001). Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells. J. Biol. Chem. 276, 25318-25323. doi: 10.1074/jbc. M102630200.
    • (2001) J. Biol. Chem , vol.276 , pp. 25318-25323
    • Kawada, N.1    Kristensen, D.B.2    Asahina, K.3    Nakatani, K.4    Minamiyama, Y.5    Seki, S.6
  • 24
    • 0027190038 scopus 로고
    • The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus
    • Kawada, N., Tran-Thi, T. A., Klein, H., and Decker, K. (1993). The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus. Eur. J. Biochem. 213, 815-823.
    • (1993) Eur. J. Biochem , vol.213 , pp. 815-823
    • Kawada, N.1    Tran-Thi, T.A.2    Klein, H.3    Decker, K.4
  • 25
    • 0032742051 scopus 로고    scopus 로고
    • Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential
    • Knittel, T., Kobold, D., Saile, B., Grundmann, A., Neubauer, K., Piscaglia, F., et al. (1999). Rat liver myofibroblasts and hepatic stellate cells: different cell populations of the fibroblast lineage with fibrogenic potential. Gastroenterology 117, 1205-1221. doi: 10.1016/S0016-5085(99)70407-5.
    • (1999) Gastroenterology , vol.117 , pp. 1205-1221
    • Knittel, T.1    Kobold, D.2    Saile, B.3    Grundmann, A.4    Neubauer, K.5    Piscaglia, F.6
  • 26
    • 84932087603 scopus 로고    scopus 로고
    • ΔNp63 targets cytoglobin to inhibit oxidative stress-induced apoptosis in keratinocytes and lung cancer
    • [Epub ahead of print]
    • Latina, A., Viticchiè, G., Lena, A. M., Piro, M. C., Annicchiarico-Petruzzelli, M., Melino, G., et al. (2015). ΔNp63 targets cytoglobin to inhibit oxidative stress-induced apoptosis in keratinocytes and lung cancer. Oncogene. doi: 10.1038/onc.2015.222. [Epub ahead of print].
    • (2015) Oncogene
    • Latina, A.1    Viticchiè, G.2    Lena, A.M.3    Piro, M.C.4    Annicchiarico-Petruzzelli, M.5    Melino, G.6
  • 27
    • 84928898387 scopus 로고    scopus 로고
    • Pathobiology of liver fibrosis: a translational success story
    • Lee, Y. A., Wallace, M. C., and Friedman, S. L. (2015). Pathobiology of liver fibrosis: a translational success story. Gut 64, 830-841. doi: 10.1136/gutjnl-2014-306842.
    • (2015) Gut , vol.64 , pp. 830-841
    • Lee, Y.A.1    Wallace, M.C.2    Friedman, S.L.3
  • 28
    • 84923398507 scopus 로고    scopus 로고
    • Portal myofibroblasts promote vascular remodeling underlying cirrhosis formation through the release of microparticles
    • Lemoinne, S., Cadoret, A., Rautou, P. E., El Mourabit, H., Ratziu, V., Corpechot, C., et al. (2015). Portal myofibroblasts promote vascular remodeling underlying cirrhosis formation through the release of microparticles. Hepatology 61, 1041-1055. doi: 10.1002/hep.27318.
    • (2015) Hepatology , vol.61 , pp. 1041-1055
    • Lemoinne, S.1    Cadoret, A.2    Rautou, P.E.3    El Mourabit, H.4    Ratziu, V.5    Corpechot, C.6
  • 29
    • 34250861281 scopus 로고    scopus 로고
    • Cytoglobin up-regulated by hydrogen peroxide plays a protective role in oxidative stress
    • Li, D., Chen, X. Q., Li, W. J., Yang, Y. H., Wang, J. Z., and Yu, A. C. (2007). Cytoglobin up-regulated by hydrogen peroxide plays a protective role in oxidative stress. Neurochem. Res. 32, 1375-1380. doi: 10.1007/s11064-007-9317-x.
    • (2007) Neurochem. Res , vol.32 , pp. 1375-1380
    • Li, D.1    Chen, X.Q.2    Li, W.J.3    Yang, Y.H.4    Wang, J.Z.5    Yu, A.C.6
  • 30
    • 84873461095 scopus 로고    scopus 로고
    • Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury
    • Li, Y., Wang, J., and Asahina, K. (2013). Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury. Proc. Natl. Acad. Sci. U.S.A. 110, 2324-2329. doi: 10.1073/pnas.1214136110.
    • (2013) Proc. Natl. Acad. Sci. U.S.A , vol.110 , pp. 2324-2329
    • Li, Y.1    Wang, J.2    Asahina, K.3
  • 31
    • 84862845350 scopus 로고    scopus 로고
    • Characterization of the function of cytoglobin as an oxygen-dependent regulator of nitric oxide concentration
    • Liu, X., Follmer, D., Zweier, J. R., Huang, X., Hemann, C., Liu, K., et al. (2012). Characterization of the function of cytoglobin as an oxygen-dependent regulator of nitric oxide concentration. Biochemistry 51, 5072-5082. doi: 10.1021/bi300291h.
    • (2012) Biochemistry , vol.51 , pp. 5072-5082
    • Liu, X.1    Follmer, D.2    Zweier, J.R.3    Huang, X.4    Hemann, C.5    Liu, K.6
  • 32
    • 84904673615 scopus 로고    scopus 로고
    • GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis
    • Lopez-Sanchez, I., Dunkel, Y., Roh, Y. S., Mittal, Y., De Minicis, S., Muranyi, A., et al. (2014). GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis. Nat. Commun. 5, 4451. doi: 10.1038/ncomms5451.
    • (2014) Nat. Commun , vol.5 , pp. 4451
    • Lopez-Sanchez, I.1    Dunkel, Y.2    Roh, Y.S.3    Mittal, Y.4    De Minicis, S.5    Muranyi, A.6
  • 33
    • 84903266958 scopus 로고    scopus 로고
    • Mesodermal mesenchymal cells give rise to myofibroblasts, but not epithelial cells, in mouse liver injury
    • Lua, I., James, D., Wang, J., Wang, K. S., and Asahina, K. (2014). Mesodermal mesenchymal cells give rise to myofibroblasts, but not epithelial cells, in mouse liver injury. Hepatology 60, 311-322. doi: 10.1002/hep.27035.
    • (2014) Hepatology , vol.60 , pp. 311-322
    • Lua, I.1    James, D.2    Wang, J.3    Wang, K.S.4    Asahina, K.5
  • 34
    • 79952487366 scopus 로고    scopus 로고
    • Crystal structure of the carbon monoxide complex of human cytoglobin
    • Makino, M., Sawai, H., Shiro, Y., and Sugimoto, H. (2011). Crystal structure of the carbon monoxide complex of human cytoglobin. Proteins 79, 1143-1153. doi: 10.1002/prot.22950.
    • (2011) Proteins , vol.79 , pp. 1143-1153
    • Makino, M.1    Sawai, H.2    Shiro, Y.3    Sugimoto, H.4
  • 35
    • 33744468238 scopus 로고    scopus 로고
    • High-resolution structure of human cytoglobin: identification of extra N-and C-termini and a new dimerization mode
    • Makino, M., Sugimoto, H., Sawai, H., Kawada, N., Yoshizato, K., and Shiro, Y. (2006). High-resolution structure of human cytoglobin: identification of extra N-and C-termini and a new dimerization mode. Acta Crystallogr. D Biol. Crystallogr. 62, 671-677. doi: 10.1107/S0907444906013813.
    • (2006) Acta Crystallogr. D Biol. Crystallogr , vol.62 , pp. 671-677
    • Makino, M.1    Sugimoto, H.2    Sawai, H.3    Kawada, N.4    Yoshizato, K.5    Shiro, Y.6
  • 36
    • 56549090632 scopus 로고    scopus 로고
    • Localization and expression pattern of cytoglobin in carbon tetrachloride-induced liver fibrosis
    • Man, K. N., Philipsen, S., and Tan-Un, K. C. (2008). Localization and expression pattern of cytoglobin in carbon tetrachloride-induced liver fibrosis. Toxicol. Lett. 183, 36-44. doi: 10.1016/j.toxlet.2008.09.015.
    • (2008) Toxicol. Lett , vol.183 , pp. 36-44
    • Man, K.N.1    Philipsen, S.2    Tan-Un, K.C.3
  • 37
    • 0036107548 scopus 로고    scopus 로고
    • Transcriptional regulation of hepatic stellate cell activation
    • Mann, D. A., and Smart, D. E. (2002). Transcriptional regulation of hepatic stellate cell activation. Gut 50, 891-896. doi: 10.1136/gut.50.6.891.
    • (2002) Gut , vol.50 , pp. 891-896
    • Mann, D.A.1    Smart, D.E.2
  • 38
    • 84888339170 scopus 로고    scopus 로고
    • Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology
    • Mederacke, I., Hsu, C. C., Troeger, J. S., Huebener, P., Mu, X., Dapito, D. H., et al. (2013). Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology. Nat. Commun. 4, 2823. doi: 10.1038/ncomms3823.
    • (2013) Nat. Commun , vol.4 , pp. 2823
    • Mederacke, I.1    Hsu, C.C.2    Troeger, J.S.3    Huebener, P.4    Mu, X.5    Dapito, D.H.6
  • 39
    • 84861098384 scopus 로고    scopus 로고
    • Gene expression profiles and differential cytoglobin expression in atrophy and adenocarcinoma of the prostate
    • Mogal, A. P., Watson, M. A., Ozsolak, F., Salavaggione, L., and Humphrey, P. A. (2012). Gene expression profiles and differential cytoglobin expression in atrophy and adenocarcinoma of the prostate. Prostate 72, 931-937. doi: 10.1002/pros.21494.
    • (2012) Prostate , vol.72 , pp. 931-937
    • Mogal, A.P.1    Watson, M.A.2    Ozsolak, F.3    Salavaggione, L.4    Humphrey, P.A.5
  • 40
    • 84893234732 scopus 로고    scopus 로고
    • Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver
    • Motoyama, H., Komiya, T., Thuy le, T. T., Tamori, A., Enomoto, M., Morikawa, H., et al. (2014). Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver. Lab. Invest. 94, 192-207. doi: 10.1038/labinvest.2013.135.
    • (2014) Lab. Invest , vol.94 , pp. 192-207
    • Motoyama, H.1    Komiya, T.2    Thuy le, T.T.3    Tamori, A.4    Enomoto, M.5    Morikawa, H.6
  • 41
    • 85047691361 scopus 로고    scopus 로고
    • Cytoglobin/STAP, its unique localization in splanchnic fibroblast-like cells and function in organ fibrogenesis
    • Nakatani, K., Okuyama, H., Shimahara, Y., Saeki, S., Kim, D. H., Nakajima, Y., et al. (2004). Cytoglobin/STAP, its unique localization in splanchnic fibroblast-like cells and function in organ fibrogenesis. Lab. Invest. 84, 91-101. doi: 10.1038/labinvest.3700013.
    • (2004) Lab. Invest , vol.84 , pp. 91-101
    • Nakatani, K.1    Okuyama, H.2    Shimahara, Y.3    Saeki, S.4    Kim, D.H.5    Nakajima, Y.6
  • 43
    • 84856751507 scopus 로고    scopus 로고
    • The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells
    • Novo, E., Povero, D., Busletta, C., Paternostro, C., di Bonzo, L. V., Cannito, S., et al. (2012). The biphasic nature of hypoxia-induced directional migration of activated human hepatic stellate cells. J. Pathol. 226, 588-597. doi: 10.1002/path.3005.
    • (2012) J. Pathol , vol.226 , pp. 588-597
    • Novo, E.1    Povero, D.2    Busletta, C.3    Paternostro, C.4    di Bonzo, L.V.5    Cannito, S.6
  • 44
    • 84867002762 scopus 로고    scopus 로고
    • MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis
    • Ogawa, T., Enomoto, M., Fujii, H., Sekiya, Y., Yoshizato, K., Ikeda, K., et al. (2012). MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis. Gut 61, 1600-1609. doi: 10.1136/gutjnl-2011-300717.
    • (2012) Gut , vol.61 , pp. 1600-1609
    • Ogawa, T.1    Enomoto, M.2    Fujii, H.3    Sekiya, Y.4    Yoshizato, K.5    Ikeda, K.6
  • 45
    • 33846442463 scopus 로고    scopus 로고
    • Identification of vitamin A-free cells in a stellate cell-enriched fraction of normal rat liver as myofibroblasts
    • Ogawa, T., Tateno, C., Asahina, K., Fujii, H., Kawada, N., Obara, M., et al. (2007). Identification of vitamin A-free cells in a stellate cell-enriched fraction of normal rat liver as myofibroblasts. Histochem. Cell Biol. 127, 161-174. doi: 10.1007/s00418-006-0237-7.
    • (2007) Histochem. Cell Biol , vol.127 , pp. 161-174
    • Ogawa, T.1    Tateno, C.2    Asahina, K.3    Fujii, H.4    Kawada, N.5    Obara, M.6
  • 46
    • 84881218522 scopus 로고    scopus 로고
    • Cytoglobin has bimodal: tumour suppressor and oncogene functions in lung cancer cell lines
    • Oleksiewicz, U., Liloglou, T., Tasopoulou, K. M., Daskoulidou, N., Bryan, J., Gosney, J. R., et al. (2013). Cytoglobin has bimodal: tumour suppressor and oncogene functions in lung cancer cell lines. Hum. Mol. Genet. 22, 3207-3217. doi: 10.1093/hmg/ddt174.
    • (2013) Hum. Mol. Genet , vol.22 , pp. 3207-3217
    • Oleksiewicz, U.1    Liloglou, T.2    Tasopoulou, K.M.3    Daskoulidou, N.4    Bryan, J.5    Gosney, J.R.6
  • 47
    • 84896806249 scopus 로고    scopus 로고
    • Liver fibrosis and repair: immune regulation of wound healing in a solid organ
    • Pellicoro, A., Ramachandran, P., Iredale, J. P., and Fallowfield, J. A. (2014). Liver fibrosis and repair: immune regulation of wound healing in a solid organ. Nat. Rev. Immunol. 14, 181-194. doi: 10.1038/nri3623.
    • (2014) Nat. Rev. Immunol , vol.14 , pp. 181-194
    • Pellicoro, A.1    Ramachandran, P.2    Iredale, J.P.3    Fallowfield, J.A.4
  • 48
    • 84878235678 scopus 로고    scopus 로고
    • Hepatic stellate cells and portal fibroblasts are the major cellular sources of collagens and lysyl oxidases in normal liver and early after injury
    • Perepelyuk, M., Terajima, M., Wang, A. Y., Georges, P. C., Janmey, P. A., Yamauchi, M., et al. (2013). Hepatic stellate cells and portal fibroblasts are the major cellular sources of collagens and lysyl oxidases in normal liver and early after injury. Am. J. Physiol. Gastrointest. Liver Physiol. 304, G605-G614. doi: 10.1152/ajpgi.00222.2012.
    • (2013) Am. J. Physiol. Gastrointest. Liver Physiol , vol.304 , pp. G605-G614
    • Perepelyuk, M.1    Terajima, M.2    Wang, A.Y.3    Georges, P.C.4    Janmey, P.A.5    Yamauchi, M.6
  • 49
    • 84874488611 scopus 로고    scopus 로고
    • Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptor-induced TIMP-1 gene transcription in hepatic stellate cells in mice
    • Perugorria, M. J., Murphy, L. B., Fullard, N., Chakraborty, J. B., Vyrla, D., Wilson, C. L., et al. (2013). Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptor-induced TIMP-1 gene transcription in hepatic stellate cells in mice. Hepatology 57, 1238-1249. doi: 10.1002/hep.26108.
    • (2013) Hepatology , vol.57 , pp. 1238-1249
    • Perugorria, M.J.1    Murphy, L.B.2    Fullard, N.3    Chakraborty, J.B.4    Vyrla, D.5    Wilson, C.L.6
  • 50
    • 0018419977 scopus 로고
    • Contractile fibroblasts in chronic alcoholic cirrhosis
    • Rudolph, R., McClure, W. J., and Woodward, M. (1979). Contractile fibroblasts in chronic alcoholic cirrhosis. Gastroenterology 76, 704-709.
    • (1979) Gastroenterology , vol.76 , pp. 704-709
    • Rudolph, R.1    McClure, W.J.2    Woodward, M.3
  • 51
    • 10744220623 scopus 로고    scopus 로고
    • Cytoglobin is a respiratory protein in connective tissue and neurons, which is up-regulated by hypoxia
    • Schmidt, M., Gerlach, F., Avivi, A., Laufs, T., Wystub, S., Simpson, J. C., et al. (2004). Cytoglobin is a respiratory protein in connective tissue and neurons, which is up-regulated by hypoxia. J. Biol. Chem. 279, 8063-8069. doi: 10.1074/jbc. M310540200.
    • (2004) J. Biol. Chem , vol.279 , pp. 8063-8069
    • Schmidt, M.1    Gerlach, F.2    Avivi, A.3    Laufs, T.4    Wystub, S.5    Simpson, J.C.6
  • 52
    • 0025821563 scopus 로고
    • Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers
    • Schmitt-Gräff, A., Krüger, S., Bochard, F., Gabbiani, G., and Denk, H. (1991). Modulation of alpha smooth muscle actin and desmin expression in perisinusoidal cells of normal and diseased human livers. Am. J. Pathol. 138, 1233-1242.
    • (1991) Am. J. Pathol , vol.138 , pp. 1233-1242
    • Schmitt-Gräff, A.1    Krüger, S.2    Bochard, F.3    Gabbiani, G.4    Denk, H.5
  • 53
    • 77956158103 scopus 로고    scopus 로고
    • Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice
    • Scholten, D., Osterreicher, C. H., Scholten, A., Iwaisako, K., Gu, G., Brenner, D. A., et al. (2010). Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice. Gastroenterology 139, 987-998. doi: 10.1053/j.gastro.2010.05.005.
    • (2010) Gastroenterology , vol.139 , pp. 987-998
    • Scholten, D.1    Osterreicher, C.H.2    Scholten, A.3    Iwaisako, K.4    Gu, G.5    Brenner, D.A.6
  • 54
    • 84877141184 scopus 로고    scopus 로고
    • Evolving therapies for liver fibrosis
    • Schuppan, D., and Kim, Y. O. (2013). Evolving therapies for liver fibrosis. J. Clin. Invest. 123, 1887-1901. doi: 10.1172/JCI66028.
    • (2013) J. Clin. Invest , vol.123 , pp. 1887-1901
    • Schuppan, D.1    Kim, Y.O.2
  • 55
    • 80051784270 scopus 로고    scopus 로고
    • Suppression of hepatic stellate cell activation by microRNA-29b
    • Sekiya, Y., Ogawa, T., Yoshizato, K., Ikeda, K., and Kawada, N. (2011). Suppression of hepatic stellate cell activation by microRNA-29b. Biochem. Biophys. Res. Commun. 412, 74-79. doi: 10.1016/j.bbrc.2011.07.041.
    • (2011) Biochem. Biophys. Res. Commun , vol.412 , pp. 74-79
    • Sekiya, Y.1    Ogawa, T.2    Yoshizato, K.3    Ikeda, K.4    Kawada, N.5
  • 56
    • 67649863684 scopus 로고    scopus 로고
    • Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer
    • Shaw, R. J., Omar, M. M., Rokadiya, S., Kogera, F. A., Lowe, D., Hall, G. L., et al. (2009). Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer. Br. J. Cancer 101, 139-144. doi: 10.1038/sj.bjc.6605121.
    • (2009) Br. J. Cancer , vol.101 , pp. 139-144
    • Shaw, R.J.1    Omar, M.M.2    Rokadiya, S.3    Kogera, F.A.4    Lowe, D.5    Hall, G.L.6
  • 57
    • 54749135818 scopus 로고    scopus 로고
    • Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene
    • Shivapurkar, N., Stastny, V., Okumura, N., Girard, L., Xie, Y., Prinsen, C., et al. (2008). Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene. Cancer Res. 68, 7448-7456. doi: 10.1158/0008-5472.CAN-08-0565.
    • (2008) Cancer Res , vol.68 , pp. 7448-7456
    • Shivapurkar, N.1    Stastny, V.2    Okumura, N.3    Girard, L.4    Xie, Y.5    Prinsen, C.6
  • 58
    • 84939513415 scopus 로고    scopus 로고
    • Cytoglobin expression in the hepatic stellate cell line HSC-T6 is regulated by extracellular matrix proteins dependent on FAK-signalling
    • Stone, L. C., Thorne, L. S., Weston, C. J., Graham, M., and Hodges, N. J. (2015). Cytoglobin expression in the hepatic stellate cell line HSC-T6 is regulated by extracellular matrix proteins dependent on FAK-signalling. Fibrogenesis Tissue Repair 8, 15. doi: 10.1186/s13069-015-0032-y.
    • (2015) Fibrogenesis Tissue Repair , vol.8 , pp. 15
    • Stone, L.C.1    Thorne, L.S.2    Weston, C.J.3    Graham, M.4    Hodges, N.J.5
  • 59
    • 84865262157 scopus 로고    scopus 로고
    • a1-and a5-containing laminins regulate the development of bile ducts via ß1 integrin signals
    • Tanimizu, N., Kikkawa, Y., Mitaka, T., and Miyajima, A. (2012). a1-and a5-containing laminins regulate the development of bile ducts via ß1 integrin signals. J. Biol. Chem. 287, 28586-28597. doi: 10.1074/jbc. M112.350488.
    • (2012) J. Biol. Chem , vol.287 , pp. 28586-28597
    • Tanimizu, N.1    Kikkawa, Y.2    Mitaka, T.3    Miyajima, A.4
  • 60
    • 4043086346 scopus 로고    scopus 로고
    • Typing of hepatic nonparenchymal cells using fibulin-2 and cytoglobin/STAP as liver fibrogenesis-related markers
    • Tateaki, Y., Ogawa, T., Kawada, N., Kohashi, T., Arihiro, K., Tateno, C., et al. (2004). Typing of hepatic nonparenchymal cells using fibulin-2 and cytoglobin/STAP as liver fibrogenesis-related markers. Histochem. Cell Biol. 122, 41-49. doi: 10.1007/s00418-004-0666-0.
    • (2004) Histochem. Cell Biol , vol.122 , pp. 41-49
    • Tateaki, Y.1    Ogawa, T.2    Kawada, N.3    Kohashi, T.4    Arihiro, K.5    Tateno, C.6
  • 61
    • 84925308488 scopus 로고    scopus 로고
    • Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway
    • Thuy le, T. T., Matsumoto, Y., Thuy, T. T., Hai, H., Suoh, M., Urahara, Y., et al. (2015). Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway. Am. J. Pathol. 185, 1045-1060. doi: 10.1016/j.ajpath.2014.12.017.
    • (2015) Am. J. Pathol , vol.185 , pp. 1045-1060
    • Thuy le, T.T.1    Matsumoto, Y.2    Thuy, T.T.3    Hai, H.4    Suoh, M.5    Urahara, Y.6
  • 62
    • 80052494651 scopus 로고    scopus 로고
    • Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice
    • Thuy le, T. T., Morita, T., Yoshida, K., Wakasa, K., Iizuka, M., Ogawa, T., et al. (2011). Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice. Am. J. Pathol. 179, 1050-1060. doi: 10.1016/j.ajpath.2011.05.006.
    • (2011) Am. J. Pathol , vol.179 , pp. 1050-1060
    • Thuy le, T.T.1    Morita, T.2    Yoshida, K.3    Wakasa, K.4    Iizuka, M.5    Ogawa, T.6
  • 63
    • 0037205447 scopus 로고    scopus 로고
    • A ubiquitously expressed human hexacoordinate hemoglobin
    • Trent, J. T. III, and Hargrove, M. S. (2002). A ubiquitously expressed human hexacoordinate hemoglobin. J. Biol. Chem. 277, 19538-19545. doi: 10.1074/jbc. M201934200.
    • (2002) J. Biol. Chem , vol.277 , pp. 19538-19545
    • Trent, J.T.1    Hargrove, M.S.2
  • 64
    • 0019230284 scopus 로고
    • Perisinusoidal stellate cells (fat-storing cells, interstitial cells, lipocytes), their related structure in and around the liver sinusoids, and vitamin A-storing cells in extrahepatic organs
    • Wake, K. (1980). Perisinusoidal stellate cells (fat-storing cells, interstitial cells, lipocytes), their related structure in and around the liver sinusoids, and vitamin A-storing cells in extrahepatic organs. Int. Rev. Cytol. 66, 303-353. doi: 10.1016/S0074-7696(08)61977-4.
    • (1980) Int. Rev. Cytol , vol.66 , pp. 303-353
    • Wake, K.1
  • 65
    • 84902985947 scopus 로고    scopus 로고
    • The portal fibroblast: not just a poor man's stellate cell
    • Wells, R. G. (2014). The portal fibroblast: not just a poor man's stellate cell. Gastroenterology 147, 41-47. doi: 10.1053/j.gastro.2014.05.001.
    • (2014) Gastroenterology , vol.147 , pp. 41-47
    • Wells, R.G.1
  • 66
    • 84861766061 scopus 로고    scopus 로고
    • Chromosome 17q25 genes, RHBDF2 and CYGB, in ovarian cancer
    • Wojnarowicz, P. M., Provencher, D. M., Mes-Masson, A. M., and Tonin, P. N. (2012). Chromosome 17q25 genes, RHBDF2 and CYGB, in ovarian cancer. Int. J. Oncol. 40, 1865-1880. doi: 10.3892/ijo.2012.1371.
    • (2012) Int. J. Oncol , vol.40 , pp. 1865-1880
    • Wojnarowicz, P.M.1    Provencher, D.M.2    Mes-Masson, A.M.3    Tonin, P.N.4
  • 67
    • 84896709837 scopus 로고    scopus 로고
    • NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice
    • Wree, A., Eguchi, A., McGeough, M. D., Pena, C. A., Johnson, C. D., Canbay, A., et al. (2014). NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice. Hepatology 59, 898-910. doi: 10.1002/hep.26592.
    • (2014) Hepatology , vol.59 , pp. 898-910
    • Wree, A.1    Eguchi, A.2    McGeough, M.D.3    Pena, C.A.4    Johnson, C.D.5    Canbay, A.6
  • 68
    • 33646888232 scopus 로고    scopus 로고
    • Cytoglobin overexpression protects against damage-induced fibrosis
    • Xu, R., Harrison, P. M., Chen, M., Li, L., Tsui, T. Y., Fung, P. C., et al. (2006). Cytoglobin overexpression protects against damage-induced fibrosis. Mol. Ther. 13, 1093-1100. doi: 10.1016/j.ymthe.2005.11.027.
    • (2006) Mol. Ther , vol.13 , pp. 1093-1100
    • Xu, R.1    Harrison, P.M.2    Chen, M.3    Li, L.4    Tsui, T.Y.5    Fung, P.C.6
  • 69
    • 84877139427 scopus 로고    scopus 로고
    • Hepatic stellate cells in liver development, regeneration, and cancer
    • Yin, C., Evason, K. J., Asahina, K., and Stainier, D. Y. (2013). Hepatic stellate cells in liver development, regeneration, and cancer. J. Clin. Invest. 123, 1902-1910. doi: 10.1172/JCI66369.
    • (2013) J. Clin. Invest , vol.123 , pp. 1902-1910
    • Yin, C.1    Evason, K.J.2    Asahina, K.3    Stainier, D.Y.4
  • 70
    • 84879888338 scopus 로고    scopus 로고
    • Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
    • Yoshimoto, S., Loo, T. M., Atarashi, K., Kanda, H., Sato, S., Oyadomari, S., et al. (2013). Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome. Nature 499, 97-101. doi: 10.1038/nature12347.
    • (2013) Nature , vol.499 , pp. 97-101
    • Yoshimoto, S.1    Loo, T.M.2    Atarashi, K.3    Kanda, H.4    Sato, S.5    Oyadomari, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.