Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer

British Journal of Cancer

Volumn 101, Issue 1, 2009, Pages 139-144

  Shaw, R J ^a,b   Omar, M M ^a   Rokadiya, S ^a   Kogera, F A ^a   Lowe, D ^b   Hall, G L ^a   Woolgar, J A ^a   Homer, J ^c   Liloglou, T ^a   Field, J K ^a   Risk, J M ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY HOSPITAL AINTREE   (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

CYGB; Head and neck squamous cell carcinoma; HIF1 a; Hypoxia; Methylation

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CYTOGLOBIN; MESSENGER RNA; GLOBIN; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

ARTICLE; CANCER CELL CULTURE; CELL HYPOXIA; CLINICAL ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEAD AND NECK CANCER; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIC CELL; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; SQUAMOUS CELL CARCINOMA; UPREGULATION; BIOSYNTHESIS; DNA METHYLATION; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HELA CELL; METABOLISM; MOUTH TUMOR; OROPHARYNX TUMOR; TUMOR CELL LINE;

CARCINOMA, SQUAMOUS CELL; CELL HYPOXIA; CELL LINE, TUMOR; DNA METHYLATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GLOBINS; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MOUTH NEOPLASMS; OROPHARYNGEAL NEOPLASMS; PROMOTER REGIONS, GENETIC; RNA, MESSENGER; UP-REGULATION;

EID: 67649863684     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6605121     Document Type: Article

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