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Volumn 8, Issue 1, 2015, Pages

Cytoglobin expression in the hepatic stellate cell line HSC-T6 is regulated by extracellular matrix proteins dependent on FAK-signalling

Author keywords

Cytoglobin; Fibrosis; Focal adhesion kinase; Hepatic stellate cell; Liver

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ALPHA2 INTEGRIN; COLLAGEN TYPE 1; CYTOGLOBIN; FOCAL ADHESION KINASE; GELATIN; LAMININ; REACTIVE OXYGEN METABOLITE; RETINOIC ACID; SCLEROPROTEIN;

EID: 84939513415     PISSN: None     EISSN: 17551536     Source Type: Journal    
DOI: 10.1186/s13069-015-0032-y     Document Type: Article
Times cited : (11)

References (68)
  • 1
    • 0036551274 scopus 로고    scopus 로고
    • Activation of hepatic stellate cells-a key issue in liver fibrosis
    • Reeves HL, Friedman SL. Activation of hepatic stellate cells-a key issue in liver fibrosis. Front Biosci. 2002;7:D808-26. doi:10.2741/reeves.
    • (2002) Front Biosci. , vol.7 , pp. D808-D826
    • Reeves, H.L.1    Friedman, S.L.2
  • 2
    • 0037899248 scopus 로고    scopus 로고
    • Liver extracellular matrix in health and disease
    • Bedossa P, Paradis V. Liver extracellular matrix in health and disease. J Pathol. 2003;200(4):504-15. doi:10.1002/path.1397.
    • (2003) J Pathol. , vol.200 , Issue.4 , pp. 504-515
    • Bedossa, P.1    Paradis, V.2
  • 3
    • 0031882258 scopus 로고    scopus 로고
    • Computer morphometry for quantitative measurement of liver fibrosis: Comparison with Knodell's score, colorimetry and conventional description reports
    • Lin XZ, Horng MH, Sun YN, Shiesh SC, Chow NH, Guo XZ. Computer morphometry for quantitative measurement of liver fibrosis: Comparison with Knodell's score, colorimetry and conventional description reports. J Gastroenterol Hepatol. 1998;13(1):75-80. doi:10.1111/j.1440-1746.1998.tb00549.x.
    • (1998) J Gastroenterol Hepatol. , vol.13 , Issue.1 , pp. 75-80
    • Lin, X.Z.1    Horng, M.H.2    Sun, Y.N.3    Shiesh, S.C.4    Chow, N.H.5    Guo, X.Z.6
  • 4
    • 0028789311 scopus 로고
    • The extracellular matrix in hepatic regeneration
    • Martinez-Hernandez A, Amenta PS. The extracellular matrix in hepatic regeneration. FASEB J. 1995;9(14):1401-10.
    • (1995) FASEB J. , vol.9 , Issue.14 , pp. 1401-1410
    • Martinez-Hernandez, A.1    Amenta, P.S.2
  • 5
    • 56349107309 scopus 로고    scopus 로고
    • Hepatic fibrosis-overview
    • Friedman SL. Hepatic fibrosis-overview. Toxicology. 2008;254(3):120-9. doi:10.1016/j.tox.2008.06.013.
    • (2008) Toxicology. , vol.254 , Issue.3 , pp. 120-129
    • Friedman, S.L.1
  • 6
    • 84856401734 scopus 로고    scopus 로고
    • Liver fibrosis: signals leading to the amplification of the fibrogenic hepatic stellate cell
    • Gabele E, Brenner DA, Rippe RA. Liver fibrosis: signals leading to the amplification of the fibrogenic hepatic stellate cell. Front Biosci. 2003;8:d69-77.
    • (2003) Front Biosci. , vol.8 , pp. d69-d77
    • Gabele, E.1    Brenner, D.A.2    Rippe, R.A.3
  • 7
    • 35948954244 scopus 로고    scopus 로고
    • Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver
    • Friedman SL. Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver. Physiol Rev. 2008;88(1):125-72. doi:10.1152/physrev.00013.2007.
    • (2008) Physiol Rev. , vol.88 , Issue.1 , pp. 125-172
    • Friedman, S.L.1
  • 8
    • 0034100952 scopus 로고    scopus 로고
    • Is liver fibrosis reversible?
    • Benyon RC, Iredale JP. Is liver fibrosis reversible? Gut. 2000;46(4):443-6. doi:10.1136/gut.46.4.443.
    • (2000) Gut. , vol.46 , Issue.4 , pp. 443-446
    • Benyon, R.C.1    Iredale, J.P.2
  • 9
    • 42949163491 scopus 로고    scopus 로고
    • Mechanisms of hepatic fibrogenesis
    • Friedman SL. Mechanisms of hepatic fibrogenesis. Gastroenterology. 2008;134(6):1655-69. doi:10.1053/j.gastro.2008.03.003.
    • (2008) Gastroenterology. , vol.134 , Issue.6 , pp. 1655-1669
    • Friedman, S.L.1
  • 10
    • 0029913735 scopus 로고    scopus 로고
    • Expression and function of integrin receptors for collagen and laminin in cultured human hepatic stellate cells
    • Carloni V, Romanelli RG, Pinzani M, Laffi G, Gentilini P. Expression and function of integrin receptors for collagen and laminin in cultured human hepatic stellate cells. Gastroenterology. 1996;110(4):1127-36. doi:10.1053/gast.1996.v110.pm8613002.
    • (1996) Gastroenterology. , vol.110 , Issue.4 , pp. 1127-1136
    • Carloni, V.1    Romanelli, R.G.2    Pinzani, M.3    Laffi, G.4    Gentilini, P.5
  • 11
    • 61949262034 scopus 로고    scopus 로고
    • Integrins and cell-fate determination
    • Streuli CH. Integrins and cell-fate determination. J Cell Sci. 2009;122(2):171-7. doi:10.1242/jcs.018945.
    • (2009) J Cell Sci. , vol.122 , Issue.2 , pp. 171-177
    • Streuli, C.H.1
  • 12
    • 0028987936 scopus 로고
    • Integrins and signal-transduction pathways-the road taken
    • Clark EA, Brugge JS. Integrins and signal-transduction pathways-the road taken. Science. 1995;268(5208):233-9. doi:10.1126/science.7716514.
    • (1995) Science. , vol.268 , Issue.5208 , pp. 233-239
    • Clark, E.A.1    Brugge, J.S.2
  • 13
    • 16644368209 scopus 로고    scopus 로고
    • Integrin bidirectional signaling: a molecular view
    • Qin J, Vinogradova O, Plow EF. Integrin bidirectional signaling: a molecular view. PLoS Biol. 2004;2(6):726-9. doi:e169 10.1371/journal.pbio.0020169.
    • (2004) PLoS Biol. , vol.2 , Issue.6 , pp. 726-729
    • Qin, J.1    Vinogradova, O.2    Plow, E.F.3
  • 15
    • 0242596627 scopus 로고    scopus 로고
    • Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells (vol 276, pg 25318, 2001)
    • Kawada N, Kristensen DB, Asahina K, Nakatani K, Minamiyama Y, Seki S, et al. Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells (vol 276, pg 25318, 2001). J Biol Chem. 2001;276(50):47744-5.
    • (2001) J Biol Chem. , vol.276 , Issue.50 , pp. 47744-47745
    • Kawada, N.1    Kristensen, D.B.2    Asahina, K.3    Nakatani, K.4    Minamiyama, Y.5    Seki, S.6
  • 16
    • 10744220623 scopus 로고    scopus 로고
    • Cytoglobin is a respiratory protein in connective tissue and neurons, which is up-regulated by hypoxia
    • Schmidt M, Gerlach F, Avivi A, Laufs T, Wystub S, Simpson JC, et al. Cytoglobin is a respiratory protein in connective tissue and neurons, which is up-regulated by hypoxia. J Biol Chem. 2004;279(9):8063-9. doi:10.1074/jbc.M310540200.
    • (2004) J Biol Chem. , vol.279 , Issue.9 , pp. 8063-8069
    • Schmidt, M.1    Gerlach, F.2    Avivi, A.3    Laufs, T.4    Wystub, S.5    Simpson, J.C.6
  • 17
    • 56549090632 scopus 로고    scopus 로고
    • Localization and expression pattern of cytoglobin in carbon tetrachloride-induced liver fibrosis
    • Man KN, Philipsen S, Tan-Un KC. Localization and expression pattern of cytoglobin in carbon tetrachloride-induced liver fibrosis. Toxicol Lett. 2008;183(1-3):36-44. doi:10.1016/j.toxlet.2008.09.015.
    • (2008) Toxicol Lett. , vol.183 , Issue.1-3 , pp. 36-44
    • Man, K.N.1    Philipsen, S.2    Tan-Un, K.C.3
  • 19
    • 0032900608 scopus 로고    scopus 로고
    • Hemoglobin is an honorary enzyme
    • Brunori M. Hemoglobin is an honorary enzyme. Trends Biochem Sci. 1999;24(4):158-61. doi:10.1016/s0968-0004(99)01380-8.
    • (1999) Trends Biochem Sci. , vol.24 , Issue.4 , pp. 158-161
    • Brunori, M.1
  • 22
    • 0003739602 scopus 로고
    • Hemoglobin-molecular, genetic, and clinical aspects
    • Bunn FH, Forget BG. Hemoglobin-molecular, genetic, and clinical aspects. Hemoglobin Mol Gen Clin Asp. 1986;10(5):483-49.
    • (1986) Hemoglobin Mol Gen Clin Asp. , vol.10 , Issue.5 , pp. 483-490
    • Bunn, F.H.1    Forget, B.G.2
  • 23
    • 58249102180 scopus 로고    scopus 로고
    • Regulation and role of neuroglobin and cytoglobin under hypoxia
    • Roach RC, Wagner PD, Hackett PH, editors. Berlin: Springer-Verlag Berlin
    • Burmester T, Gerlach F, Hankeln T. Regulation and role of neuroglobin and cytoglobin under hypoxia. In: Roach RC, Wagner PD, Hackett PH, editors. Hypoxia and the Circulation. Advances in Experimental Medicine and Biology. Berlin: Springer-Verlag Berlin; 2007. p. 169-80.
    • (2007) Hypoxia and the Circulation: Advances in Experimental Medicine and Biology , pp. 169-180
    • Burmester, T.1    Gerlach, F.2    Hankeln, T.3
  • 24
    • 79952144810 scopus 로고    scopus 로고
    • Lipid binding to cytoglobin leads to a change in haem co-ordination: a role for cytoglobin in lipid signalling of oxidative stress
    • Reeder BJ, Svistunenko DA, Wilson MT. Lipid binding to cytoglobin leads to a change in haem co-ordination: a role for cytoglobin in lipid signalling of oxidative stress. Biochem J. 2011;434:483-92. doi:10.1042/bj20101136.
    • (2011) Biochem J. , vol.434 , pp. 483-492
    • Reeder, B.J.1    Svistunenko, D.A.2    Wilson, M.T.3
  • 25
    • 0036219963 scopus 로고    scopus 로고
    • Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues
    • Burmester T, Ebner B, Weich B, Hankeln T. Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues. Mol Biol Evol. 2002;19(4):416-21.
    • (2002) Mol Biol Evol. , vol.19 , Issue.4 , pp. 416-421
    • Burmester, T.1    Ebner, B.2    Weich, B.3    Hankeln, T.4
  • 26
    • 0038333244 scopus 로고    scopus 로고
    • Characterization of the heme environmental structure of cytoglobin, a fourth globin in humans
    • Sawai H, Kawada N, Yoshizato K, Nakajima H, Aono S, Shiro Y. Characterization of the heme environmental structure of cytoglobin, a fourth globin in humans. Biochemistry. 2003;42(17):5133-42. doi:10.1021/bi027067e.
    • (2003) Biochemistry. , vol.42 , Issue.17 , pp. 5133-5142
    • Sawai, H.1    Kawada, N.2    Yoshizato, K.3    Nakajima, H.4    Aono, S.5    Shiro, Y.6
  • 27
    • 85047691361 scopus 로고    scopus 로고
    • Cytoglobin/STAP, its unique localization in splanchnic fibroblast-like cells and function in organ fibrogenesis
    • Nakatani K, Okuyama H, Shimahara Y, Saeki S, Kim DH, Nakajima Y, et al. Cytoglobin/STAP, its unique localization in splanchnic fibroblast-like cells and function in organ fibrogenesis. Lab Invest. 2004;84(1):91-101. doi:10.1038/labinvest.3700013.
    • (2004) Lab Invest. , vol.84 , Issue.1 , pp. 91-101
    • Nakatani, K.1    Okuyama, H.2    Shimahara, Y.3    Saeki, S.4    Kim, D.H.5    Nakajima, Y.6
  • 28
    • 33646888232 scopus 로고    scopus 로고
    • Cytoglobin overexpression protects against damage-induced fibrosis
    • Xu R, Harrison PM, Chen M, Li L, Tsui TY, Fung PC, et al. Cytoglobin overexpression protects against damage-induced fibrosis. Mol Ther. 2006;13(6):1093-100. doi:10.1016/j.ymthe.2005.11.027.
    • (2006) Mol Ther. , vol.13 , Issue.6 , pp. 1093-1100
    • Xu, R.1    Harrison, P.M.2    Chen, M.3    Li, L.4    Tsui, T.Y.5    Fung, P.C.6
  • 29
    • 0842301109 scopus 로고    scopus 로고
    • Structure and function of hepatic stellate cells
    • Senoo H. Structure and function of hepatic stellate cells. Med Electron Microsc. 2004;37(1):3-15. doi:10.1007/s00795-003-0230-3.
    • (2004) Med Electron Microsc. , vol.37 , Issue.1 , pp. 3-15
    • Senoo, H.1
  • 30
    • 33846968462 scopus 로고    scopus 로고
    • Neuroglobin and cytoglobin expression in mice-evidence for a correlation with reactive oxygen species scavenging
    • Fordel E, Thijs L, Moens L, Dewilde S. Neuroglobin and cytoglobin expression in mice-evidence for a correlation with reactive oxygen species scavenging. Febs J. 2007;274(5):1312-7. doi:10.1111/j.1742-4658.2007.05679.x.
    • (2007) Febs J. , vol.274 , Issue.5 , pp. 1312-1317
    • Fordel, E.1    Thijs, L.2    Moens, L.3    Dewilde, S.4
  • 31
    • 4644255532 scopus 로고    scopus 로고
    • Hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure
    • Nangaku M. Hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. Nephron Exp Nephrol. 2004;98(1):E8-E12. doi:10.1159/000079927.
    • (2004) Nephron Exp Nephrol. , vol.98 , Issue.1 , pp. E8-E12
    • Nangaku, M.1
  • 32
    • 77955010960 scopus 로고    scopus 로고
    • Hypoxia: a Link between fibrogenesis, angiogenesis, and carcinogenesis in liver disease
    • Rosmorduc O, Housset C. Hypoxia: a Link between fibrogenesis, angiogenesis, and carcinogenesis in liver disease. Semin Liver Dis. 2010;30(3):258-70. doi:10.1055/s-0030-1255355.
    • (2010) Semin Liver Dis. , vol.30 , Issue.3 , pp. 258-270
    • Rosmorduc, O.1    Housset, C.2
  • 33
    • 27144435897 scopus 로고    scopus 로고
    • Effects of hypoxia on the alveolar epithelium
    • Jain M, Sznajder JI. Effects of hypoxia on the alveolar epithelium. Proc Am Thorac Soc. 2005;2(3):202-5. doi:10.1513/pats.200501-006AC.
    • (2005) Proc Am Thorac Soc. , vol.2 , Issue.3 , pp. 202-205
    • Jain, M.1    Sznajder, J.I.2
  • 34
    • 44349140101 scopus 로고    scopus 로고
    • Hypoxia-inducible factor signaling in the development of tissue fibrosis
    • Higgins DF, Kimura K, Iwano M, Haase VH. Hypoxia-inducible factor signaling in the development of tissue fibrosis. Cell Cycle. 2008;7(9):1128-32. doi:10.4161/cc.7.9.5804.
    • (2008) Cell Cycle. , vol.7 , Issue.9 , pp. 1128-1132
    • Higgins, D.F.1    Kimura, K.2    Iwano, M.3    Haase, V.H.4
  • 35
    • 46349108421 scopus 로고    scopus 로고
    • Cellular protection from oxidative DNA damage by over-expression of the novel globin cytoglobin in vitro
    • Hodges NJ, Innocent N, Dhanda S, Graham M. Cellular protection from oxidative DNA damage by over-expression of the novel globin cytoglobin in vitro. Mutagenesis. 2008;23(4):293-8. doi:10.1093/mutage/gen013.
    • (2008) Mutagenesis. , vol.23 , Issue.4 , pp. 293-298
    • Hodges, N.J.1    Innocent, N.2    Dhanda, S.3    Graham, M.4
  • 36
  • 37
    • 79251520307 scopus 로고    scopus 로고
    • Cytoglobin, a novel member of the globin family, protects kidney fibroblasts against oxidative stress under ischemic conditions
    • Nishi H, Inagi R, Kawada N, Yoshizato K, Mimura I, Fujita T, et al. Cytoglobin, a novel member of the globin family, protects kidney fibroblasts against oxidative stress under ischemic conditions. Am J Pathol. 2011;178(1):128-39. doi:10.1016/j.ajpath.2010.11.011.
    • (2011) Am J Pathol. , vol.178 , Issue.1 , pp. 128-139
    • Nishi, H.1    Inagi, R.2    Kawada, N.3    Yoshizato, K.4    Mimura, I.5    Fujita, T.6
  • 38
    • 84857136158 scopus 로고    scopus 로고
    • Protection from intracellular oxidative stress by cytoglobin in normal and cancerous oesophageal cells
    • McRonald FE, Risk JM, Hodges NJ. Protection from intracellular oxidative stress by cytoglobin in normal and cancerous oesophageal cells. PLoS One. 2012;7(2):e30587. doi:10.1371/journal.pone.0030587.
    • (2012) PLoS One. , vol.7 , Issue.2
    • McRonald, F.E.1    Risk, J.M.2    Hodges, N.J.3
  • 40
    • 0024314801 scopus 로고
    • Maintenance of differentiated phenotype of cultured rat hepatic lipocytes by basement-membrane matrix
    • Friedman SL, Roll FJ, Boyles J, Arenson DM, Bissell DM. Maintenance of differentiated phenotype of cultured rat hepatic lipocytes by basement-membrane matrix. J Biol Chem. 1989;264(18):10756-62.
    • (1989) J Biol Chem. , vol.264 , Issue.18 , pp. 10756-10762
    • Friedman, S.L.1    Roll, F.J.2    Boyles, J.3    Arenson, D.M.4    Bissell, D.M.5
  • 41
    • 14244257340 scopus 로고    scopus 로고
    • Adipogenic transcriptional regulation of hepatic stellate cells
    • She HY, Xiong SG, Hazra S, Tsukamoto H. Adipogenic transcriptional regulation of hepatic stellate cells. J Biol Chem. 2005;280(6):4959-67. doi:10.1074/jbc.M410078200.
    • (2005) J Biol Chem. , vol.280 , Issue.6 , pp. 4959-4967
    • She, H.Y.1    Xiong, S.G.2    Hazra, S.3    Tsukamoto, H.4
  • 42
    • 55449126714 scopus 로고    scopus 로고
    • Cell survival, activation and apoptosis of hepatic stellate cells: modulation by extracellular matrix proteins
    • Priya S, Sudhakaran PR. Cell survival, activation and apoptosis of hepatic stellate cells: modulation by extracellular matrix proteins. Hepatol Res. 2008;38(12):1221-32. doi:10.1111/j.1872-034X.2008.00394.x.
    • (2008) Hepatol Res. , vol.38 , Issue.12 , pp. 1221-1232
    • Priya, S.1    Sudhakaran, P.R.2
  • 43
    • 0033921113 scopus 로고    scopus 로고
    • An immortalized rat liver stellate cell line (HSC-T6): a new cell model for the study of retinoid metabolism in vitro
    • Vogel S, Piantedosi R, Frank J, Lalazar A, Rockey DC, Friedman SL, et al. An immortalized rat liver stellate cell line (HSC-T6): a new cell model for the study of retinoid metabolism in vitro. J Lipid Res. 2000;41(6):882-93.
    • (2000) J Lipid Res. , vol.41 , Issue.6 , pp. 882-893
    • Vogel, S.1    Piantedosi, R.2    Frank, J.3    Lalazar, A.4    Rockey, D.C.5    Friedman, S.L.6
  • 44
    • 84862195154 scopus 로고    scopus 로고
    • Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis
    • Kisseleva T, Cong M, Paik Y, Scholten D, Jiang CY, Benner C, et al. Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci U S A. 2012;109(24):9448-53. doi:10.1073/pnas.1201840109.
    • (2012) Proc Natl Acad Sci U S A. , vol.109 , Issue.24 , pp. 9448-9453
    • Kisseleva, T.1    Cong, M.2    Paik, Y.3    Scholten, D.4    Jiang, C.Y.5    Benner, C.6
  • 45
    • 84867119109 scopus 로고    scopus 로고
    • Liver fibrosis: a bidirectional model of fibrogenesis and resolution
    • Ramachandran P, Iredale JP. Liver fibrosis: a bidirectional model of fibrogenesis and resolution. QJM. 2012. doi:hcs069 [pii]10.1093/qjmed/hcs069.
    • (2012) QJM
    • Ramachandran, P.1    Iredale, J.P.2
  • 46
    • 33646341752 scopus 로고    scopus 로고
    • Sensing extracellular matrix: an update on discoidin domain receptor function
    • Vogel WF, Abdulhussein R, Ford CE. Sensing extracellular matrix: an update on discoidin domain receptor function. Cell Signal. 2006;18(8):1108-16. doi:10.1016/j.cellsig.2006.02.012.
    • (2006) Cell Signal. , vol.18 , Issue.8 , pp. 1108-1116
    • Vogel, W.F.1    Abdulhussein, R.2    Ford, C.E.3
  • 47
  • 48
    • 0034254009 scopus 로고    scopus 로고
    • The collagen receptor integrins have distinct ligand recognition and signaling functions
    • Heino J. The collagen receptor integrins have distinct ligand recognition and signaling functions. Matrix Biol. 2000;19(4):319-23.
    • (2000) Matrix Biol. , vol.19 , Issue.4 , pp. 319-323
    • Heino, J.1
  • 49
    • 80054036560 scopus 로고    scopus 로고
    • Transmembrane collagen receptors
    • Leitinger B. Transmembrane collagen receptors. Annu Rev Cell Dev Biol. 2011;27:265-90. doi:10.1146/annurev-cellbio-092910-154013.
    • (2011) Annu Rev Cell Dev Biol. , vol.27 , pp. 265-290
    • Leitinger, B.1
  • 50
    • 84898478868 scopus 로고    scopus 로고
    • Redox-relevant aspects of the extracellular matrix and its cellular contacts via integrins
    • Eble JA, de Rezende FF. Redox-relevant aspects of the extracellular matrix and its cellular contacts via integrins. Antioxid Redox Signal. 2014;20(13):1977-93. doi:10.1089/ars.2013.5294.
    • (2014) Antioxid Redox Signal. , vol.20 , Issue.13 , pp. 1977-1993
    • Eble, J.A.1    de Rezende, F.F.2
  • 51
    • 84870319857 scopus 로고    scopus 로고
    • Focal adhesion kinase and reactive oxygen species contribute to the persistent fibrotic phenotype of lesional scleroderma fibroblasts
    • Shi-wen X, Thompson K, Khan K, Liu S, Murphy-Marshman H, Baron M, et al. Focal adhesion kinase and reactive oxygen species contribute to the persistent fibrotic phenotype of lesional scleroderma fibroblasts. Rheumatology (Oxford). 2012;51(12):2146-54. doi:10.1093/rheumatology/kes234.
    • (2012) Rheumatology (Oxford). , vol.51 , Issue.12 , pp. 2146-2154
    • Shi-wen, X.1    Thompson, K.2    Khan, K.3    Liu, S.4    Murphy-Marshman, H.5    Baron, M.6
  • 52
    • 84878117509 scopus 로고    scopus 로고
    • Integrin-linked kinase mediates the hydrogen peroxide-dependent transforming growth factor-beta1 up-regulation
    • Gonzalez-Ramos M, de Frutos S, Griera M, Luengo A, Olmos G, Rodriguez-Puyol D, et al. Integrin-linked kinase mediates the hydrogen peroxide-dependent transforming growth factor-beta1 up-regulation. Free Radic Biol Med. 2013;61:416-27. doi:10.1016/j.freeradbiomed.2013.04.029.
    • (2013) Free Radic Biol Med. , vol.61 , pp. 416-427
    • Gonzalez-Ramos, M.1    de Frutos, S.2    Griera, M.3    Luengo, A.4    Olmos, G.5    Rodriguez-Puyol, D.6
  • 53
    • 84931837035 scopus 로고    scopus 로고
    • EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-beta/Smad and ROS signaling
    • Park SA, Kim MJ, Park SY, Kim JS, Lee SJ,Woo HA, et al. EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-beta/Smad and ROS signaling. Cell Mol Life Sci. 2015;72(10):2023-39. doi:10.1007/s00018-014-1798-6.
    • (2015) Cell Mol Life Sci. , vol.72 , Issue.10 , pp. 2023-2039
    • Park, S.A.1    Kim, M.J.2    Park, S.Y.3    Kim, J.S.4    Lee, S.J.5    Woo, H.A.6
  • 54
    • 33751003841 scopus 로고    scopus 로고
    • Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice
    • Choi SS, Sicklick JK, Ma Q, Yang L, Huang J, Qi Y, et al. Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice. Hepatology. 2006;44(5):1267-77. doi:10.1002/hep.21375.
    • (2006) Hepatology. , vol.44 , Issue.5 , pp. 1267-1277
    • Choi, S.S.1    Sicklick, J.K.2    Ma, Q.3    Yang, L.4    Huang, J.5    Qi, Y.6
  • 55
    • 33750705253 scopus 로고    scopus 로고
    • Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death
    • Fordel E, Thijs L, Martinet W, Lenjou M, Laufs T, Van Bockstaele D, et al. Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death. Neurosci Lett. 2006;410(2):146-51. doi:10.1016/j.neulet.2006.09.027.
    • (2006) Neurosci Lett. , vol.410 , Issue.2 , pp. 146-151
    • Fordel, E.1    Thijs, L.2    Martinet, W.3    Lenjou, M.4    Laufs, T.5    Van Bockstaele, D.6
  • 56
    • 79961040632 scopus 로고    scopus 로고
    • Knockdown of cytoglobin expression sensitizes human glioma cells to radiation and oxidative stress
    • Fang J, Ma I, Allalunis-Turner J. Knockdown of cytoglobin expression sensitizes human glioma cells to radiation and oxidative stress. Radiat Res. 2011;176(2):198-207.
    • (2011) Radiat Res. , vol.176 , Issue.2 , pp. 198-207
    • Fang, J.1    Ma, I.2    Allalunis-Turner, J.3
  • 57
    • 80555155985 scopus 로고    scopus 로고
    • Role of cytoglobin in protecting hepatic stellate cells against oxidation induced damage
    • Lu Y, Wang Q, Li Z, Diao Y, Xu R. Role of cytoglobin in protecting hepatic stellate cells against oxidation induced damage. Sheng Wu Gong Cheng Xue Bao. 2011;27(8):1174-82.
    • (2011) Sheng Wu Gong Cheng Xue Bao. , vol.27 , Issue.8 , pp. 1174-1182
    • Lu, Y.1    Wang, Q.2    Li, Z.3    Diao, Y.4    Xu, R.5
  • 58
    • 84925308488 scopus 로고    scopus 로고
    • Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway
    • le Thuy TT, Matsumoto Y, Thuy TT, Hai H, Suoh M, Urahara Y, et al. Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway. Am J Pathol. 2015;185(4):1045-60. doi:10.1016/j.ajpath.2014.12.017.
    • (2015) Am J Pathol. , vol.185 , Issue.4 , pp. 1045-1060
    • le Thuy, T.T.1    Matsumoto, Y.2    Thuy, T.T.3    Hai, H.4    Suoh, M.5    Urahara, Y.6
  • 59
    • 84908025562 scopus 로고    scopus 로고
    • TGF-β1-elevated TRPM7 channel regulates collagen expression in hepatic stellate cells via TGF-β1/ Smad pathway
    • Fang L, Huang C, Meng X, Wu B, Ma T, Liu X, et al. TGF-β1-elevated TRPM7 channel regulates collagen expression in hepatic stellate cells via TGF-β1/ Smad pathway. Toxicol Appl Pharmacol. 2014;280(2):335-44. doi:10.1016/j.taap.2014.08.006.
    • (2014) Toxicol Appl Pharmacol. , vol.280 , Issue.2 , pp. 335-344
    • Fang, L.1    Huang, C.2    Meng, X.3    Wu, B.4    Ma, T.5    Liu, X.6
  • 60
    • 84859050434 scopus 로고    scopus 로고
    • Notch3 regulates the activation of hepatic stellate cells
    • Chen Y-XX, Weng Z-HH, Zhang S-LL. Notch3 regulates the activation of hepatic stellate cells. World J Gastroenterol. 2012;18(12):1397-403. doi:10.3748/wjg.v18.i12.1397.
    • (2012) World J Gastroenterol. , vol.18 , Issue.12 , pp. 1397-1403
    • Chen, Y.-X.X.1    Weng, Z.-H.H.2    Zhang, S.-L.L.3
  • 62
    • 84865539649 scopus 로고    scopus 로고
    • Inhibition of the activation of hepatic stellate cells by arundic acid via the induction of cytoglobin
    • Cui WH, Wang M, Maegawa H, Teranishi Y, Kawada N. Inhibition of the activation of hepatic stellate cells by arundic acid via the induction of cytoglobin. Biochem Biophys Res Commun. 2012;425(3):642-8. doi:10.1016/j.bbrc.2012.07.126.
    • (2012) Biochem Biophys Res Commun. , vol.425 , Issue.3 , pp. 642-648
    • Cui, W.H.1    Wang, M.2    Maegawa, H.3    Teranishi, Y.4    Kawada, N.5
  • 63
    • 84989169447 scopus 로고    scopus 로고
    • Cytoglobin deficiency promotes live fibrosis and liver cancer development in mice with steatohepatitis throughout activating oxidative stress pathway
    • Le TT, Suoh M, Matsumoto Y, Shimada M, Hirano Y, Motoyama H, et al. Cytoglobin deficiency promotes live fibrosis and liver cancer development in mice with steatohepatitis throughout activating oxidative stress pathway. Hepatology. 2012;56:865A-A.
    • (2012) Hepatology. , vol.56 , pp. 865A-A
    • Le, T.T.1    Suoh, M.2    Matsumoto, Y.3    Shimada, M.4    Hirano, Y.5    Motoyama, H.6
  • 65
    • 10844242987 scopus 로고    scopus 로고
    • Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis
    • Xu L, Hui AY, Albanis E, Arthur MJ, O'Byrne SM, Blaner WS, et al. Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis. Gut. 2005;54(1):142-51. doi:10.1136/gut.2004.042127.
    • (2005) Gut. , vol.54 , Issue.1 , pp. 142-151
    • Xu, L.1    Hui, A.Y.2    Albanis, E.3    Arthur, M.J.4    O'Byrne, S.M.5    Blaner, W.S.6
  • 66
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-54.
    • (1976) Anal Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 67
    • 0027531682 scopus 로고
    • A new approach for measurement of cytotoxicity using colorimetric assay
    • Hussain RF, Nouri AM, Oliver RT. A new approach for measurement of cytotoxicity using colorimetric assay. J Immunol Methods. 1993;160(1):89-96.
    • (1993) J Immunol Methods. , vol.160 , Issue.1 , pp. 89-96
    • Hussain, R.F.1    Nouri, A.M.2    Oliver, R.T.3
  • 68
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001;29:9. doi:10.1093/nar/29.9.e45.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 9
    • Pfaffl, M.W.1


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