Inhibition of the activation of hepatic stellate cells by arundic acid via the induction of cytoglobin

Biochemical and Biophysical Research Communications

Volumn 425, Issue 3, 2012, Pages 642-648

  Cui, Wenhao ^a   Wang, Miao ^b   Maegawa, Hitoshi ^c   Teranishi, Yuga ^a   Kawada, Norifumi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c ONO PHARMACEUTICAL CO   (Japan)

Author keywords

Smooth muscle actin; Chronic hepatitis; Collagen; Cytoglobin; Liver fibrosis

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ARUNDIC ACID; COLLAGEN TYPE 1; COLLAGEN TYPE 1ALPHA1; CYTOGLOBIN; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL LINE; CELL STRUCTURE; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; STELLATE CELL;

ANIMALS; CAPRYLATES; CELLS, CULTURED; COLLAGEN TYPE I; GENE EXPRESSION; GLOBINS; HEPATIC STELLATE CELLS; LIVER CIRRHOSIS; MALE; RATS; RATS, WISTAR;

MAMMALIA; RATTUS;

EID: 84865539649     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.07.126     Document Type: Article

References (26)

1. Friedman S.L. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J. Biol. Chem. 2000, 275:2247-2250.
2. Bataller R., Brenner D.A. Liver fibrosis. J. Clin. Invest. 2005, 115:209-218.
3. Tateishi N., Mori T., Kagamiishi Y., Satoh S., Katsube N., Morikawa E., Morimoto T., Matsui T., Asano T., et al. Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part II: suppression of astrocytic activation by a novel agent (R)-(-)-2-propyloctanoic acid (ONO-2506) leads to mitigation of delayed infarct expansion and early improvement of neurologic deficits. J. Cereb. Blood Flow Metab. 2002, 22:723-734.
4. Mori T., Town T., Tan J., et al. Arundic acid ameliorates cerebral amyloidosis and gliosis in Alzheimer transgenic mice. J. Pharmacol. Exp. Ther. 2006, 318:71-78.
5. Schachtrup C., Le Moan N., Passino M.A., et al. Hepatic stellate cells and astrocytes: stars of scar formation and tissue repair. Cell Cycle 2011, 10:1764-1771.
6. Buniatian G.H., Hartmann H.J., Traub P., et al. Acquisition of blood-tissue barrier-supporting features by hepatic stellate cells and astrocytes of myofibroblastic phenotype. Inverse dynamics of metallothionein and glial fibrillary acidic protein expression. Neurochem. Int. 2001, 38:373-383.
7. Kawada N., Kristensen D.B., Asahina K., et al. Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells. J. Biol. Chem. 2001, 276:25318-25323.
8. Oleksiewicz U., Liloglou T., Field J.K., et al. Cytoglobin: biochemical, functional and clinical perspective of the newest member of the globin family. Cell Mol. Life Sci. 2011, 68:3869-3883.
9. Thuy le T.T., Morita T., Yoshida K., et al. Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice. Am. J. Pathol. 2011, 179:1050-1060.
10. He X., Lv R., Wang K., et al. Cytoglobin exhibits anti-fibrosis activity on liver in vivo and in vitro. Protein J. 2011, 30:437-446.
11. Kristensen D.B., Kawada N., Imamura K., et al. Proteome analysis of rat hepatic stellate cells. Hepatology 2000, 32:268-277.
12. Xu L., Hui A.Y., Albanis E., et al. Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis. Gut 2005, 54:142-151.
13. Asano T., Mori T., Shimoda T., et al. Arundic acid (ONO-2506) ameliorates delayed ischemic brain damage by preventing astrocytic overproduction of S100B. Curr. Drug Targets CNS Neurol. Disord. 2005, 4:127-142.
14. Ishibashi H., Pettigrew L.C., Funakoshi Y., et al. Pharmacokinetics of arundic acid, an astrocyte modulating agent, in acute ischemic stroke. J. Clin. Pharmacol. 2007, 47:445-452.
15. Pettigrew L.C., Kasner S.E., Albers G.W., et al. Safety and tolerability of arundic acid in acute ischemic stroke. J. Neurol. Sci. 2006, 251:50-56.
16. Cui W., Matsuno K., Iwata K., et al. NOX1/nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) oxidase promotes proliferation of stellate cells and aggravates liver fibrosis induced by bile duct ligation. Hepatology 2011, 54:949-958.
17. Fordel E., Thijs L., Martinet W., et al. Neuroglobin and cytoglobin overexpression protects human SH-SY5Y neuroblastoma cells against oxidative stress-induced cell death. Neurosci. Lett. 2006, 410:146-151.
18. Nishi H., Inagi R., Kawada N., et al. Cytoglobin, a novel member of the globin family, protects kidney fibroblasts against oxidative stress under ischemic conditions. Am. J. Pathol. 2011, 178:128-139.
19. Svegliati Baroni G., D'Ambrosio L., Ferretti G., et al. Fibrogenic effect of oxidative stress on rat hepatic stellate cells. Hepatology 1998, 27:720-726.
20. Galli A., Svegliati-Baroni G., Ceni E., et al. Oxidative stress stimulates proliferation and invasiveness of hepatic stellate cells via a MMP2-mediated mechanism. Hepatology 2005, 41:1074-1084.
21. Takenaga K., Nakamura Y., Sakiyama S. Expression of antisense RNA to S100A4 gene encoding an S100-related calcium-binding protein suppresses metastatic potential of high-metastatic Lewis lung carcinoma cells. Oncogene 1997, 14:331-337.
22. Lloyd B.H., Platt-Higgins A., Rudland P.S., et al. Human S100A4 (p9Ka) induces the metastatic phenotype upon benign tumour cells. Oncogene 1998, 17:465-473.
23. Sack U., Walther W., Scudiero D., et al. S100A4-induced cell motility and metastasis is restricted by the Wnt/beta-catenin pathway inhibitor calcimycin in colon cancer cells. Mol. Biol. Cell 2011, 22:3344-3354.
24. Cunningham M.F., Docherty N.G., Burke J.P., et al. S100A4 expression is increased in stricture fibroblasts from patients with fibrostenosing Crohn's disease and promotes intestinal fibroblast migration. Am. J. Physiol. Gastrointest. Liver Physiol. 2010, 299:G457-466.
25. Matsuura I., Lai C.Y., Chiang K.N. Functional interaction between Smad3 and S100A4 (metastatin-1) for TGF-beta-mediated cancer cell invasiveness. Biochem. J. 2010, 426:327-335.
26. Osterreicher C.H., Penz-Osterreicher M., Grivennikov S.I., et al. Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver. Proc. Natl. Acad. Sci. USA 2011, 108:308-313.