Mesothelial cells give rise to hepatic stellate cells and myofibroblasts via mesothelial-mesenchymal transition in liver injury

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 6, 2013, Pages 2324-2329

  Li, Yuchang ^a   Wang, Jiaohong ^a   Asahina, Kinji ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Alpha smooth muscle actin; Epithelial mesenchymal transition; Fibrosis; Glisson's capsule; Podoplanin

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LINEAGE; CELL POLARITY; CELL TRANSDIFFERENTIATION; CELL TRANSFORMATION; CONTROLLED STUDY; EMBRYO; FIBROGENESIS; LIVER INJURY; MESENCHYME CELL; MESOTHELIAL MESENCHYMAL TRANSITION; MESOTHELIUM CELL; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STELLATE CELL; UPREGULATION;

ANIMALS; BILIARY TRACT; CARBON TETRACHLORIDE; CELL LINEAGE; CELL TRANSDIFFERENTIATION; CELLS, CULTURED; DRUG-INDUCED LIVER INJURY; EPITHELIUM; GENE EXPRESSION; HEPATIC STELLATE CELLS; LIVER; LIVER CIRRHOSIS; LIVER REGENERATION; MEMBRANE GLYCOPROTEINS; MESODERM; MICE; MICE, TRANSGENIC; MYOFIBROBLASTS; NERVE TISSUE PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; WT1 PROTEINS;

EID: 84873461095     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1214136110     Document Type: Article

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