Nutrient deprivation induces α-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathway

Frontiers in Aging Neuroscience

Volumn 6, Issue OCT, 2014, Pages

  Jiang, Peizhou ^a   Gan, Ming ^a   Lin, Wen Lang ^a   Yen, Shu Hui C ^a  

^a MAYO CLINIC   (United States)

Author keywords

Aggregation; Autophagy; ER stress; Nutrient deprivation; Parkinson's disease; SREBP2; synuclein

Indexed keywords

ALPHA SYNUCLEIN; MEVINOLIN; POLYGLUTAMINE; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TETRACYCLINE;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL VIABILITY; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MOUSE; NERVE CELL; NONHUMAN; NUTRIENT; NUTRIENT DEPRIVATION; PARKINSON DISEASE; PROTEIN AGGREGATION;

EID: 84949115685     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2014.00268     Document Type: Article

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