Endoplasmic reticulum stress leads to lipid accumulation through upregulation of SREBP-1c in normal hepatic and hepatoma cells

Molecular and Cellular Biochemistry

Volumn 381, Issue 1-2, 2013, Pages 127-137

  Fang, Dian Liang ^a   Wan, Ying ^a   Shen, Wei ^a   Cao, Jie ^a   Sun, Zhong Xin ^a   Yu, Hui Hong ^a   Zhang, Qin ^a,b   Cheng, Wen Hui ^a   Chen, Juan ^a   Ning, Bo ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b Department of Gynaecology and Obstetrics   (China)

Author keywords

Endoplasmic reticulum stress; Hepatic steatosis; SREBP 1c

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACETYL COENZYME A CARBOXYLASE 1; FATTY ACID SYNTHASE; GLUCOSE REGULATED PROTEIN 78; LIVER X RECEPTOR; MESSENGER RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM STRESS; FATTY LIVER; HEPATOBLASTOMA; HUMAN; HUMAN CELL; LIPID STORAGE; LIVER CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RIBOSOME; ROUGH ENDOPLASMIC RETICULUM; UPREGULATION; WESTERN BLOTTING;

ACETYL-COA CARBOXYLASE; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL SURVIVAL; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FATTY ACID SYNTHASES; FATTY LIVER; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HEAT-SHOCK PROTEINS; HUMANS; LIPID METABOLISM; LIVER; LIVER NEOPLASMS; ORPHAN NUCLEAR RECEPTORS; PROTEOLYSIS; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SULFONES; THAPSIGARGIN; TRIGLYCERIDES; UP-REGULATION;

EID: 84882577354     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1694-7     Document Type: Article

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