Stabilization of α-synuclein protein with aging and familial Parkinson's disease-linked A53T mutation

Journal of Neuroscience

Volumn 24, Issue 33, 2004, Pages 7400-7409

  Li, Wenxue ^a   Lesuisse, Christian ^a   Xu, Yanqun ^a   Troncoso, Juan C ^a   Price, Donald L ^a   Lee, Michael K ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Metabolism; Oxidative stress; Parkinson's disease; Synuclein; Synucleinopathy

Indexed keywords

ALPHA SYNUCLEIN; BETA SYNUCLEIN; MESSENGER RNA; PROTEASOME; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; MULTIENZYME COMPLEX; NERVE PROTEIN; SNCA PROTEIN, HUMAN; SNCA PROTEIN, MOUSE; SYNUCLEIN;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; CONTROLLED STUDY; GENE MUTATION; GENETIC LINKAGE; MOUSE; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN MODIFICATION; PROTEIN STABILITY; SUBSTANTIA NIGRA; ANIMAL; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; LYSOSOME; METABOLISM; OXIDATION REDUCTION REACTION; POINT MUTATION; PROTEIN PROCESSING; TRANSGENIC MOUSE;

AGING; ALPHA-SYNUCLEIN; ANIMALS; BRAIN; CELL DIFFERENTIATION; CELL LINE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; HUMANS; LYSOSOMES; MICE; MICE, TRANSGENIC; MULTIENZYME COMPLEXES; NERVE TISSUE PROTEINS; NEURONS; OXIDATION-REDUCTION; PARKINSON DISEASE; POINT MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA, MESSENGER; SYNUCLEINS;

EID: 7244243876     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1370-04.2004     Document Type: Article

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