Azithromycin drives alternative macrophage activation and improves recovery and tissue sparing in contusion spinal cord injury

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Zhang, Bei ^a   Bailey, William M ^a   Kopper, Timothy J ^a   Orr, Michael B ^a   Feola, David J ^b   Gensel, John C ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b University of Kentucky   (United States)

Author keywords

Alternatively activated; Azithromycin; M1; M2; Macrolide antibiotic; Macrophage; Microglia; Spinal cord injury

Indexed keywords

AZITHROMYCIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CONTUSION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; IN VITRO STUDY; LOCOMOTION; MACROPHAGE ACTIVATION; MICROGLIA; MONOCYTE; MOUSE; NEUTROPHIL; NONHUMAN; PHENOTYPE; REAL TIME POLYMERASE CHAIN REACTION; SPINAL CORD INJURY; ANIMAL; C57BL MOUSE; CELL CULTURE; CONVALESCENCE; DOSE RESPONSE; DRUG EFFECTS; MACROPHAGE; METABOLISM; PHYSIOLOGY; SPINAL CORD INJURIES; TUMOR CELL LINE;

ANIMALS; AZITHROMYCIN; CELL LINE, TUMOR; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; MACROPHAGES; MICE; MICE, INBRED C57BL; RECOVERY OF FUNCTION; SPINAL CORD INJURIES;

EID: 84949105474     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0440-3     Document Type: Article

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