Anti-inflammatory mechanism of action of azithromycin in LPS-stimulated J774A.1 cells

Pharmacological Research

Volumn 66, Issue 4, 2012, Pages 357-362

  Banjanac, Mihailo ^a,b   Munić Kos, Vesna ^a   Nujić, Krunoslav ^a   Vrančić, Mila ^a   Belamarić, Daniela ^a   Crnković, Slaven ^a   Hlevnjak, Mario ^a   Eraković Haber, Vesna ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b Galapagos Istraživački Centar Doo ^*  (Croatia)

Author keywords

Azithromycin; Cytosolic phospholipase A2; Inflammation; J774A.1 cells; LPS

Indexed keywords

ARACHIDONIC ACID; AZITHROMYCIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYTOSOLIC PHOSPHOLIPASE A2; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; ICOSANOID; INDOMETACIN; INTERLEUKIN 12P40; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROSTAGLANDIN E2;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME INHIBITION; ENZYME SUBSTRATE; FATTY ACID SYNTHESIS; INHIBITION KINETICS; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROTEIN EXPRESSION; PROTEIN INTERACTION;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARACHIDONIC ACID; AZITHROMYCIN; CELL LINE; DINOPROSTONE; EICOSANOIDS; GROUP IV PHOSPHOLIPASES A2; INDOMETHACIN; INTERLEUKIN-12 SUBUNIT P40; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84864978893     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2012.06.011     Document Type: Article

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