Azithromycin drives in vitro GM-CSF/IL-4- induced differentiation of human blood monocytes toward dendritic-like cells with regulatory properties

Journal of Leukocyte Biology

Volumn 91, Issue 2, 2012, Pages 229-243

  Polančec, Darija Stupin ^a   Kos, Vesna Munić ^a   Banjanac, Mihailo ^a   Vrančić, Mila ^a   Čužić, Snježana ^a   Belamarić, Daniela ^a   Parnham, Michael J ^b   Polančec, Denis ^a,c   Haber, Vesna Eraković ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

^b Croatia   (Croatia)

^c Galapagos Research Center   (Croatia)

Author keywords

Cytokine release; Macrolide; Phagocytosis; Phenotype; Surface marker expression

Indexed keywords

AZITHROMYCIN; CD14 ANTIGEN; CD209 ANTIGEN; CD40 ANTIGEN; CD71 ANTIGEN; CD86 ANTIGEN; COLONY STIMULATING FACTOR 1; CXCL11 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 4; INTERLEUKIN 6; MACROPHAGE DERIVED CHEMOKINE; MONOCYTE CHEMOTACTIC PROTEIN 1; T6 ANTIGEN;

ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; PERIPHERAL BLOOD MONONUCLEAR CELL; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION;

APOPTOSIS; AUTOPHAGY; AZITHROMYCIN; CELL DIFFERENTIATION; CELL SEPARATION; CELLS, CULTURED; DENDRITIC CELLS; GENE EXPRESSION REGULATION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMMUNOPHENOTYPING; INTERLEUKIN-4; JURKAT CELLS; LYMPHOCYTE CULTURE TEST, MIXED; MACROPHAGE COLONY-STIMULATING FACTOR; MONOCYTES; PHAGOCYTOSIS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; T-LYMPHOCYTES;

EID: 84856477292     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1210655     Document Type: Article

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